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fa596599 | 1 | ;;; GNU Guix --- Functional package management for GNU |
f8f181ae | 2 | ;;; Copyright © 2016, 2017, 2018, 2019, 2020 Ricardo Wurmus <rekado@elephly.net> |
6aa896d8 | 3 | ;;; Copyright © 2016, 2017, 2018 Roel Janssen <roel@gnu.org> |
61242625 | 4 | ;;; Copyright © 2017, 2018, 2019 Tobias Geerinckx-Rice <me@tobias.gr> |
16e2e4f2 | 5 | ;;; Copyright © 2019 Simon Tournier <zimon.toutoune@gmail.com> |
fa596599 RW |
6 | ;;; |
7 | ;;; This file is part of GNU Guix. | |
8 | ;;; | |
9 | ;;; GNU Guix is free software; you can redistribute it and/or modify it | |
10 | ;;; under the terms of the GNU General Public License as published by | |
11 | ;;; the Free Software Foundation; either version 3 of the License, or (at | |
12 | ;;; your option) any later version. | |
13 | ;;; | |
14 | ;;; GNU Guix is distributed in the hope that it will be useful, but | |
15 | ;;; WITHOUT ANY WARRANTY; without even the implied warranty of | |
16 | ;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the | |
17 | ;;; GNU General Public License for more details. | |
18 | ;;; | |
19 | ;;; You should have received a copy of the GNU General Public License | |
20 | ;;; along with GNU Guix. If not, see <http://www.gnu.org/licenses/>. | |
21 | ||
22 | (define-module (gnu packages bioconductor) | |
23 | #:use-module ((guix licenses) #:prefix license:) | |
24 | #:use-module (guix packages) | |
25 | #:use-module (guix download) | |
b2dce6b5 | 26 | #:use-module (guix git-download) |
fa596599 | 27 | #:use-module (guix build-system r) |
183ce988 | 28 | #:use-module (gnu packages) |
58656064 | 29 | #:use-module (gnu packages base) |
cf9a29b2 | 30 | #:use-module (gnu packages bioinformatics) |
a5b56a53 RJ |
31 | #:use-module (gnu packages cran) |
32 | #:use-module (gnu packages compression) | |
c18dccff | 33 | #:use-module (gnu packages gcc) |
cf9a29b2 | 34 | #:use-module (gnu packages graph) |
5aef09bd | 35 | #:use-module (gnu packages graphviz) |
dddbc90c | 36 | #:use-module (gnu packages haskell-xyz) |
5cfa4bff | 37 | #:use-module (gnu packages image) |
b64ce4b7 | 38 | #:use-module (gnu packages maths) |
6b12f213 RW |
39 | #:use-module (gnu packages netpbm) |
40 | #:use-module (gnu packages perl) | |
2cb71d81 | 41 | #:use-module (gnu packages pkg-config) |
f4235c0e | 42 | #:use-module (gnu packages statistics) |
14bb1c48 | 43 | #:use-module (gnu packages web) |
7a62d5e0 | 44 | #:use-module (gnu packages xml) |
14bb1c48 | 45 | #:use-module (srfi srfi-1)) |
fa596599 | 46 | |
557a1089 RW |
47 | \f |
48 | ;;; Annotations | |
49 | ||
6f15ea24 RW |
50 | (define-public r-reactome-db |
51 | (package | |
52 | (name "r-reactome-db") | |
53 | (version "1.70.0") | |
54 | (source | |
55 | (origin | |
56 | (method url-fetch) | |
57 | (uri (bioconductor-uri "reactome.db" version 'annotation)) | |
58 | (sha256 | |
59 | (base32 | |
60 | "05wc4fp0faq6h3kq5rwafnips043as31yq11mrjngfxvf5i10srg")))) | |
61 | (properties `((upstream-name . "reactome.db"))) | |
62 | (build-system r-build-system) | |
63 | (propagated-inputs | |
64 | `(("r-annotationdbi" ,r-annotationdbi))) | |
65 | (home-page "https://bioconductor.org/packages/reactome.db/") | |
66 | (synopsis "Annotation maps for reactome") | |
67 | (description | |
68 | "This package provides a set of annotation maps for the REACTOME | |
69 | database, assembled using data from REACTOME.") | |
70 | (license license:cc-by4.0))) | |
71 | ||
b7d93cf5 RW |
72 | (define-public r-bsgenome-celegans-ucsc-ce6 |
73 | (package | |
74 | (name "r-bsgenome-celegans-ucsc-ce6") | |
75 | (version "1.4.0") | |
76 | (source (origin | |
77 | (method url-fetch) | |
86ced7b2 RW |
78 | (uri (bioconductor-uri "BSgenome.Celegans.UCSC.ce6" |
79 | version 'annotation)) | |
b7d93cf5 RW |
80 | (sha256 |
81 | (base32 | |
82 | "0mqzb353xv2c3m3vkb315dkmnxkgczp7ndnknyhpgjlybyf715v9")))) | |
83 | (properties | |
84 | `((upstream-name . "BSgenome.Celegans.UCSC.ce6"))) | |
85 | (build-system r-build-system) | |
b7d93cf5 RW |
86 | (propagated-inputs |
87 | `(("r-bsgenome" ,r-bsgenome))) | |
88 | (home-page | |
89 | "https://www.bioconductor.org/packages/BSgenome.Celegans.UCSC.ce6/") | |
90 | (synopsis "Full genome sequences for Worm") | |
91 | (description | |
92 | "This package provides full genome sequences for Caenorhabditis | |
93 | elegans (Worm) as provided by UCSC (ce6, May 2008) and stored in Biostrings | |
0c792ffb RW |
94 | objects.") |
95 | (license license:artistic2.0))) | |
96 | ||
97 | (define-public r-bsgenome-celegans-ucsc-ce10 | |
98 | (package | |
99 | (name "r-bsgenome-celegans-ucsc-ce10") | |
100 | (version "1.4.0") | |
101 | (source (origin | |
102 | (method url-fetch) | |
6998ecba RW |
103 | (uri (bioconductor-uri "BSgenome.Celegans.UCSC.ce10" |
104 | version 'annotation)) | |
0c792ffb RW |
105 | (sha256 |
106 | (base32 | |
107 | "1zaym97jk4npxk14ifvwz2rvhm4zx9xgs33r9vvx9rlynp0gydrk")))) | |
108 | (properties | |
109 | `((upstream-name . "BSgenome.Celegans.UCSC.ce10"))) | |
110 | (build-system r-build-system) | |
0c792ffb RW |
111 | (propagated-inputs |
112 | `(("r-bsgenome" ,r-bsgenome))) | |
113 | (home-page | |
114 | "https://www.bioconductor.org/packages/BSgenome.Celegans.UCSC.ce10/") | |
115 | (synopsis "Full genome sequences for Worm") | |
116 | (description | |
117 | "This package provides full genome sequences for Caenorhabditis | |
118 | elegans (Worm) as provided by UCSC (ce10, Oct 2010) and stored in Biostrings | |
b7d93cf5 RW |
119 | objects.") |
120 | (license license:artistic2.0))) | |
121 | ||
183db725 RW |
122 | (define-public r-bsgenome-dmelanogaster-ucsc-dm6 |
123 | (package | |
124 | (name "r-bsgenome-dmelanogaster-ucsc-dm6") | |
125 | (version "1.4.1") | |
126 | (source (origin | |
127 | (method url-fetch) | |
149f351f RW |
128 | (uri (bioconductor-uri "BSgenome.Dmelanogaster.UCSC.dm6" |
129 | version 'annotation)) | |
183db725 RW |
130 | (sha256 |
131 | (base32 | |
132 | "1bhj0rdgf7lspw4xby9y9mf7v7jxxz8001bc8vw8kf04rjsx6060")))) | |
133 | (properties | |
134 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm6"))) | |
135 | (build-system r-build-system) | |
183db725 RW |
136 | (propagated-inputs |
137 | `(("r-bsgenome" ,r-bsgenome))) | |
138 | (home-page | |
139 | "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm6/") | |
140 | (synopsis "Full genome sequences for Fly") | |
141 | (description | |
142 | "This package provides full genome sequences for Drosophila | |
143 | melanogaster (Fly) as provided by UCSC (dm6) and stored in Biostrings | |
144 | objects.") | |
145 | (license license:artistic2.0))) | |
146 | ||
13dabd69 RW |
147 | (define-public r-bsgenome-dmelanogaster-ucsc-dm3 |
148 | (package | |
149 | (name "r-bsgenome-dmelanogaster-ucsc-dm3") | |
150 | (version "1.4.0") | |
151 | (source (origin | |
152 | (method url-fetch) | |
87073b7e RW |
153 | (uri (bioconductor-uri "BSgenome.Dmelanogaster.UCSC.dm3" |
154 | version 'annotation)) | |
13dabd69 RW |
155 | (sha256 |
156 | (base32 | |
157 | "19bm3lkhhkag3gnwp419211fh0cnr0x6fa0r1lr0ycwrikxdxsv8")))) | |
158 | (properties | |
159 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm3"))) | |
160 | (build-system r-build-system) | |
13dabd69 RW |
161 | (propagated-inputs |
162 | `(("r-bsgenome" ,r-bsgenome))) | |
163 | (home-page | |
164 | "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm3/") | |
165 | (synopsis "Full genome sequences for Fly") | |
166 | (description | |
167 | "This package provides full genome sequences for Drosophila | |
168 | melanogaster (Fly) as provided by UCSC (dm3, April 2006) and stored in | |
169 | Biostrings objects.") | |
170 | (license license:artistic2.0))) | |
171 | ||
dfac7eb9 RW |
172 | (define-public r-bsgenome-dmelanogaster-ucsc-dm3-masked |
173 | (package | |
174 | (name "r-bsgenome-dmelanogaster-ucsc-dm3-masked") | |
175 | (version "1.3.99") | |
176 | (source (origin | |
177 | (method url-fetch) | |
bf05ece1 RW |
178 | (uri (bioconductor-uri "BSgenome.Dmelanogaster.UCSC.dm3.masked" |
179 | version 'annotation)) | |
dfac7eb9 RW |
180 | (sha256 |
181 | (base32 | |
182 | "1756csb09f1br9rj1l3f08qyh4hlymdbd0cfn8x3fq39dn45m5ap")))) | |
183 | (properties | |
184 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm3.masked"))) | |
185 | (build-system r-build-system) | |
186 | (propagated-inputs | |
187 | `(("r-bsgenome" ,r-bsgenome) | |
188 | ("r-bsgenome-dmelanogaster-ucsc-dm3" | |
189 | ,r-bsgenome-dmelanogaster-ucsc-dm3))) | |
190 | (home-page "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm3.masked/") | |
191 | (synopsis "Full masked genome sequences for Fly") | |
192 | (description | |
193 | "This package provides full masked genome sequences for Drosophila | |
194 | melanogaster (Fly) as provided by UCSC (dm3, April 2006) and stored in | |
195 | Biostrings objects. The sequences are the same as in | |
196 | BSgenome.Dmelanogaster.UCSC.dm3, except that each of them has the 4 following | |
197 | masks on top: (1) the mask of assembly gaps (AGAPS mask), (2) the mask of | |
198 | intra-contig ambiguities (AMB mask), (3) the mask of repeats from | |
199 | RepeatMasker (RM mask), and (4) the mask of repeats from Tandem Repeats | |
200 | Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by default.") | |
201 | (license license:artistic2.0))) | |
202 | ||
40a65057 RW |
203 | (define-public r-bsgenome-hsapiens-1000genomes-hs37d5 |
204 | (package | |
205 | (name "r-bsgenome-hsapiens-1000genomes-hs37d5") | |
206 | (version "0.99.1") | |
207 | (source (origin | |
208 | (method url-fetch) | |
88e7c7db RW |
209 | (uri (bioconductor-uri "BSgenome.Hsapiens.1000genomes.hs37d5" |
210 | version 'annotation)) | |
40a65057 RW |
211 | (sha256 |
212 | (base32 | |
213 | "1cg0g5fqmsvwyw2p9hp2yy4ilk21jkbbrnpgqvb5c36ihjwvc7sr")))) | |
214 | (properties | |
215 | `((upstream-name . "BSgenome.Hsapiens.1000genomes.hs37d5"))) | |
216 | (build-system r-build-system) | |
40a65057 RW |
217 | (propagated-inputs |
218 | `(("r-bsgenome" ,r-bsgenome))) | |
219 | (home-page | |
220 | "https://www.bioconductor.org/packages/BSgenome.Hsapiens.1000genomes.hs37d5/") | |
221 | (synopsis "Full genome sequences for Homo sapiens") | |
222 | (description | |
223 | "This package provides full genome sequences for Homo sapiens from | |
224 | 1000genomes phase2 reference genome sequence (hs37d5), based on NCBI GRCh37.") | |
225 | (license license:artistic2.0))) | |
226 | ||
c51c0033 MIP |
227 | (define-public r-bsgenome-hsapiens-ncbi-grch38 |
228 | (package | |
229 | (name "r-bsgenome-hsapiens-ncbi-grch38") | |
230 | (version "1.3.1000") | |
231 | (source | |
232 | (origin | |
233 | (method url-fetch) | |
234 | (uri (bioconductor-uri "BSgenome.Hsapiens.NCBI.GRCh38" | |
235 | version 'annotation)) | |
236 | (sha256 | |
237 | (base32 | |
238 | "0y75qdq578fh6420vbvsbwmdw8jvr3g06qli2h3vj3pxmjykh9c1")))) | |
239 | (properties `((upstream-name . "BSgenome.Hsapiens.NCBI.GRCh38"))) | |
240 | (build-system r-build-system) | |
241 | (propagated-inputs `(("r-bsgenome" ,r-bsgenome))) | |
242 | (home-page | |
243 | "https://bioconductor.org/packages/release/data/annotation/html/\ | |
244 | BSgenome.Hsapiens.NCBI.GRCh38.html") | |
245 | (synopsis "Full genome sequences for Homo sapiens (GRCh38)") | |
246 | (description | |
247 | "This package provides full genome sequences for Homo sapiens (Human) as | |
248 | provided by NCBI (GRCh38, 2013-12-17) and stored in Biostrings objects.") | |
249 | (license license:artistic2.0))) | |
250 | ||
6fbd759b RW |
251 | (define-public r-bsgenome-hsapiens-ucsc-hg19-masked |
252 | (package | |
253 | (name "r-bsgenome-hsapiens-ucsc-hg19-masked") | |
254 | (version "1.3.99") | |
255 | (source (origin | |
256 | (method url-fetch) | |
a47646bd RW |
257 | (uri (bioconductor-uri "BSgenome.Hsapiens.UCSC.hg19.masked" |
258 | version 'annotation)) | |
6fbd759b RW |
259 | (sha256 |
260 | (base32 | |
261 | "0452pyah0kv1vsrsjbrqw4k2rm8lc2vc771dzib45gnnfz86qxrr")))) | |
262 | (properties | |
263 | `((upstream-name . "BSgenome.Hsapiens.UCSC.hg19.masked"))) | |
264 | (build-system r-build-system) | |
265 | (propagated-inputs | |
266 | `(("r-bsgenome" ,r-bsgenome) | |
267 | ("r-bsgenome-hsapiens-ucsc-hg19" | |
268 | ,r-bsgenome-hsapiens-ucsc-hg19))) | |
269 | (home-page "https://bioconductor.org/packages/BSgenome.Hsapiens.UCSC.hg19.masked/") | |
270 | (synopsis "Full masked genome sequences for Homo sapiens") | |
271 | (description | |
272 | "This package provides full genome sequences for Homo sapiens (Human) as | |
273 | provided by UCSC (hg19, Feb. 2009) and stored in Biostrings objects. The | |
274 | sequences are the same as in BSgenome.Hsapiens.UCSC.hg19, except that each of | |
275 | them has the 4 following masks on top: (1) the mask of assembly gaps (AGAPS | |
276 | mask), (2) the mask of intra-contig ambiguities (AMB mask), (3) the mask of | |
277 | repeats from RepeatMasker (RM mask), and (4) the mask of repeats from Tandem | |
278 | Repeats Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by | |
279 | default.") | |
280 | (license license:artistic2.0))) | |
281 | ||
5acb9052 RW |
282 | (define-public r-bsgenome-mmusculus-ucsc-mm9 |
283 | (package | |
284 | (name "r-bsgenome-mmusculus-ucsc-mm9") | |
285 | (version "1.4.0") | |
286 | (source (origin | |
287 | (method url-fetch) | |
21f6dae7 RW |
288 | (uri (bioconductor-uri "BSgenome.Mmusculus.UCSC.mm9" |
289 | version 'annotation)) | |
5acb9052 RW |
290 | (sha256 |
291 | (base32 | |
292 | "1birqw30g2azimxpnjfzmkphan7x131yy8b9h85lfz5fjdg7841i")))) | |
293 | (properties | |
294 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm9"))) | |
295 | (build-system r-build-system) | |
5acb9052 RW |
296 | (propagated-inputs |
297 | `(("r-bsgenome" ,r-bsgenome))) | |
298 | (home-page | |
299 | "https://www.bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9/") | |
300 | (synopsis "Full genome sequences for Mouse") | |
301 | (description | |
302 | "This package provides full genome sequences for Mus musculus (Mouse) as | |
303 | provided by UCSC (mm9, July 2007) and stored in Biostrings objects.") | |
304 | (license license:artistic2.0))) | |
305 | ||
2bece692 RW |
306 | (define-public r-bsgenome-mmusculus-ucsc-mm9-masked |
307 | (package | |
308 | (name "r-bsgenome-mmusculus-ucsc-mm9-masked") | |
309 | (version "1.3.99") | |
310 | (source (origin | |
311 | (method url-fetch) | |
51dc4a2d RW |
312 | (uri (bioconductor-uri "BSgenome.Mmusculus.UCSC.mm9.masked" |
313 | version 'annotation)) | |
2bece692 RW |
314 | (sha256 |
315 | (base32 | |
316 | "00bpbm3havqcxr4g63zhllsbpd9q6svgihks7qp7x73nm4gvq7fn")))) | |
317 | (properties | |
318 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm9.masked"))) | |
319 | (build-system r-build-system) | |
320 | (propagated-inputs | |
321 | `(("r-bsgenome" ,r-bsgenome) | |
322 | ("r-bsgenome-mmusculus-ucsc-mm9" | |
323 | ,r-bsgenome-mmusculus-ucsc-mm9))) | |
99db6db7 | 324 | (home-page "https://bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9.masked/") |
2bece692 RW |
325 | (synopsis "Full masked genome sequences for Mouse") |
326 | (description | |
327 | "This package provides full genome sequences for Mus musculus (Mouse) as | |
328 | provided by UCSC (mm9, Jul. 2007) and stored in Biostrings objects. The | |
329 | sequences are the same as in BSgenome.Mmusculus.UCSC.mm9, except that each of | |
330 | them has the 4 following masks on top: (1) the mask of assembly gaps (AGAPS | |
331 | mask), (2) the mask of intra-contig ambiguities (AMB mask), (3) the mask of | |
332 | repeats from RepeatMasker (RM mask), and (4) the mask of repeats from Tandem | |
333 | Repeats Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by | |
334 | default." ) | |
335 | (license license:artistic2.0))) | |
336 | ||
c3adc830 RW |
337 | (define-public r-bsgenome-mmusculus-ucsc-mm10 |
338 | (package | |
339 | (name "r-bsgenome-mmusculus-ucsc-mm10") | |
340 | (version "1.4.0") | |
341 | (source (origin | |
342 | (method url-fetch) | |
f83404bc RW |
343 | (uri (bioconductor-uri "BSgenome.Mmusculus.UCSC.mm10" |
344 | version 'annotation)) | |
c3adc830 RW |
345 | (sha256 |
346 | (base32 | |
347 | "12s0nm2na9brjad4rn9l7d3db2aj8qa1xvz0y1k7gk08wayb6bkf")))) | |
348 | (properties | |
349 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm10"))) | |
350 | (build-system r-build-system) | |
c3adc830 RW |
351 | (propagated-inputs |
352 | `(("r-bsgenome" ,r-bsgenome))) | |
353 | (home-page | |
354 | "https://www.bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm10/") | |
355 | (synopsis "Full genome sequences for Mouse") | |
356 | (description | |
357 | "This package provides full genome sequences for Mus | |
358 | musculus (Mouse) as provided by UCSC (mm10, December 2011) and stored | |
359 | in Biostrings objects.") | |
360 | (license license:artistic2.0))) | |
361 | ||
3a08940e RW |
362 | (define-public r-org-ce-eg-db |
363 | (package | |
364 | (name "r-org-ce-eg-db") | |
365 | (version "3.7.0") | |
366 | (source (origin | |
367 | (method url-fetch) | |
1c05e637 | 368 | (uri (bioconductor-uri "org.Ce.eg.db" version 'annotation)) |
3a08940e RW |
369 | (sha256 |
370 | (base32 | |
371 | "1w5br1ss4ha8wv4v2saj7cmbjc2jw0dyj2f2y269l078z31wcnaz")))) | |
372 | (properties | |
373 | `((upstream-name . "org.Ce.eg.db"))) | |
374 | (build-system r-build-system) | |
375 | (propagated-inputs | |
376 | `(("r-annotationdbi" ,r-annotationdbi))) | |
377 | (home-page "https://www.bioconductor.org/packages/org.Ce.eg.db/") | |
378 | (synopsis "Genome wide annotation for Worm") | |
379 | (description | |
380 | "This package provides mappings from Entrez gene identifiers to various | |
381 | annotations for the genome of the model worm Caenorhabditis elegans.") | |
382 | (license license:artistic2.0))) | |
383 | ||
f8780e96 RW |
384 | (define-public r-org-dm-eg-db |
385 | (package | |
386 | (name "r-org-dm-eg-db") | |
387 | (version "3.7.0") | |
388 | (source (origin | |
389 | (method url-fetch) | |
b0dfc79b | 390 | (uri (bioconductor-uri "org.Dm.eg.db" version 'annotation)) |
f8780e96 RW |
391 | (sha256 |
392 | (base32 | |
393 | "1pqjrzlyg72bjpy8zsxvaglc7jsv176bnyi87xdajmkvsgxpm7b3")))) | |
394 | (properties | |
395 | `((upstream-name . "org.Dm.eg.db"))) | |
396 | (build-system r-build-system) | |
397 | (propagated-inputs | |
398 | `(("r-annotationdbi" ,r-annotationdbi))) | |
399 | (home-page "https://www.bioconductor.org/packages/org.Dm.eg.db/") | |
400 | (synopsis "Genome wide annotation for Fly") | |
401 | (description | |
402 | "This package provides mappings from Entrez gene identifiers to various | |
403 | annotations for the genome of the model fruit fly Drosophila melanogaster.") | |
404 | (license license:artistic2.0))) | |
405 | ||
3dad6087 RW |
406 | (define-public r-org-dr-eg-db |
407 | (package | |
408 | (name "r-org-dr-eg-db") | |
409 | (version "3.7.0") | |
410 | (source (origin | |
411 | (method url-fetch) | |
7bb65a22 | 412 | (uri (bioconductor-uri "org.Dr.eg.db" version 'annotation)) |
3dad6087 RW |
413 | (sha256 |
414 | (base32 | |
415 | "1xs5wsbcpy0iwbjyiv7fax57djqc529ai5fk1qfsdcvlja3cpglx")))) | |
416 | (properties | |
417 | `((upstream-name . "org.Dr.eg.db"))) | |
418 | (build-system r-build-system) | |
419 | (propagated-inputs | |
420 | `(("r-annotationdbi" ,r-annotationdbi))) | |
421 | (home-page "https://www.bioconductor.org/packages/org.Dr.eg.db/") | |
422 | (synopsis "Annotation for Zebrafish") | |
423 | (description | |
424 | "This package provides genome wide annotations for Zebrafish, primarily | |
425 | based on mapping using Entrez Gene identifiers.") | |
426 | (license license:artistic2.0))) | |
427 | ||
d56df35a RW |
428 | (define-public r-org-hs-eg-db |
429 | (package | |
430 | (name "r-org-hs-eg-db") | |
431 | (version "3.7.0") | |
432 | (source (origin | |
433 | (method url-fetch) | |
f53becc6 | 434 | (uri (bioconductor-uri "org.Hs.eg.db" version 'annotation)) |
d56df35a RW |
435 | (sha256 |
436 | (base32 | |
437 | "1qxz9l80yg3qdqszs6dsscp7lrpfi1bgd0pxh9j7q34vprzwhdim")))) | |
438 | (properties | |
439 | `((upstream-name . "org.Hs.eg.db"))) | |
440 | (build-system r-build-system) | |
441 | (propagated-inputs | |
442 | `(("r-annotationdbi" ,r-annotationdbi))) | |
443 | (home-page "https://www.bioconductor.org/packages/org.Hs.eg.db/") | |
444 | (synopsis "Genome wide annotation for Human") | |
445 | (description | |
446 | "This package contains genome-wide annotations for Human, primarily based | |
447 | on mapping using Entrez Gene identifiers.") | |
448 | (license license:artistic2.0))) | |
449 | ||
8035819f RW |
450 | (define-public r-org-mm-eg-db |
451 | (package | |
452 | (name "r-org-mm-eg-db") | |
453 | (version "3.7.0") | |
454 | (source (origin | |
455 | (method url-fetch) | |
411be88b | 456 | (uri (bioconductor-uri "org.Mm.eg.db" version 'annotation)) |
8035819f RW |
457 | (sha256 |
458 | (base32 | |
459 | "1i3nvrd3wjigf1rmgxq1p5xxc3p8v02h5gwi62s30rkrsyjjfjxx")))) | |
460 | (properties | |
461 | `((upstream-name . "org.Mm.eg.db"))) | |
462 | (build-system r-build-system) | |
463 | (propagated-inputs | |
464 | `(("r-annotationdbi" ,r-annotationdbi))) | |
465 | (home-page "https://www.bioconductor.org/packages/org.Mm.eg.db/") | |
466 | (synopsis "Genome wide annotation for Mouse") | |
467 | (description | |
468 | "This package provides mappings from Entrez gene identifiers to various | |
469 | annotations for the genome of the model mouse Mus musculus.") | |
470 | (license license:artistic2.0))) | |
471 | ||
fe0b76e2 RW |
472 | (define-public r-bsgenome-hsapiens-ucsc-hg19 |
473 | (package | |
474 | (name "r-bsgenome-hsapiens-ucsc-hg19") | |
475 | (version "1.4.0") | |
476 | (source (origin | |
477 | (method url-fetch) | |
e7a8cf2e RW |
478 | (uri (bioconductor-uri "BSgenome.Hsapiens.UCSC.hg19" |
479 | version 'annotation)) | |
fe0b76e2 RW |
480 | (sha256 |
481 | (base32 | |
482 | "1y0nqpk8cw5a34sd9hmin3z4v7iqm6hf6l22cl81vlbxqbjibxc8")))) | |
483 | (properties | |
484 | `((upstream-name . "BSgenome.Hsapiens.UCSC.hg19"))) | |
485 | (build-system r-build-system) | |
fe0b76e2 RW |
486 | (propagated-inputs |
487 | `(("r-bsgenome" ,r-bsgenome))) | |
488 | (home-page | |
489 | "https://www.bioconductor.org/packages/BSgenome.Hsapiens.UCSC.hg19/") | |
490 | (synopsis "Full genome sequences for Homo sapiens") | |
491 | (description | |
492 | "This package provides full genome sequences for Homo sapiens as provided | |
493 | by UCSC (hg19, February 2009) and stored in Biostrings objects.") | |
494 | (license license:artistic2.0))) | |
495 | ||
8324e64c RW |
496 | (define-public r-ensdb-hsapiens-v75 |
497 | (package | |
498 | (name "r-ensdb-hsapiens-v75") | |
499 | (version "2.99.0") | |
500 | (source | |
501 | (origin | |
502 | (method url-fetch) | |
503 | (uri (bioconductor-uri "EnsDb.Hsapiens.v75" version 'annotation)) | |
504 | (sha256 | |
505 | (base32 | |
506 | "0jx6rf6v0j8yr07q3c1h7s121901dc400nm6xaiv4i7kb5czjn9c")))) | |
507 | (properties | |
508 | `((upstream-name . "EnsDb.Hsapiens.v75"))) | |
509 | (build-system r-build-system) | |
510 | (propagated-inputs | |
511 | `(("r-ensembldb" ,r-ensembldb))) | |
512 | (home-page "https://bioconductor.org/packages/EnsDb.Hsapiens.v75") | |
513 | (synopsis "Ensembl based annotation package") | |
514 | (description | |
515 | "This package exposes an annotation database generated from Ensembl.") | |
516 | (license license:artistic2.0))) | |
517 | ||
2cc51108 RW |
518 | (define-public r-genelendatabase |
519 | (package | |
520 | (name "r-genelendatabase") | |
daeb3cd9 | 521 | (version "1.18.0") |
2cc51108 RW |
522 | (source |
523 | (origin | |
524 | (method url-fetch) | |
717d7cda | 525 | (uri (bioconductor-uri "geneLenDataBase" version 'experiment)) |
2cc51108 RW |
526 | (sha256 |
527 | (base32 | |
daeb3cd9 | 528 | "03gm4pvsfascx7kjg0jycpf4f572mja68wwmwigs390vbmawyb4a")))) |
2cc51108 RW |
529 | (properties |
530 | `((upstream-name . "geneLenDataBase"))) | |
531 | (build-system r-build-system) | |
532 | (propagated-inputs | |
533 | `(("r-rtracklayer" ,r-rtracklayer) | |
534 | ("r-genomicfeatures" ,r-genomicfeatures))) | |
535 | (home-page "https://bioconductor.org/packages/geneLenDataBase/") | |
536 | (synopsis "Lengths of mRNA transcripts for a number of genomes") | |
537 | (description | |
538 | "This package provides the lengths of mRNA transcripts for a number of | |
539 | genomes and gene ID formats, largely based on the UCSC table browser.") | |
540 | (license license:lgpl2.0+))) | |
541 | ||
66e35ce6 RW |
542 | (define-public r-txdb-hsapiens-ucsc-hg19-knowngene |
543 | (package | |
544 | (name "r-txdb-hsapiens-ucsc-hg19-knowngene") | |
545 | (version "3.2.2") | |
546 | (source (origin | |
547 | (method url-fetch) | |
f2580a13 RW |
548 | (uri (bioconductor-uri "TxDb.Hsapiens.UCSC.hg19.knownGene" |
549 | version 'annotation)) | |
66e35ce6 RW |
550 | (sha256 |
551 | (base32 | |
552 | "1sajhcqqwazgz2lqbik7rd935i7kpnh08zxbp2ra10j72yqy4g86")))) | |
553 | (properties | |
554 | `((upstream-name . "TxDb.Hsapiens.UCSC.hg19.knownGene"))) | |
555 | (build-system r-build-system) | |
66e35ce6 RW |
556 | (propagated-inputs |
557 | `(("r-genomicfeatures" ,r-genomicfeatures))) | |
558 | (home-page | |
559 | "https://bioconductor.org/packages/TxDb.Hsapiens.UCSC.hg19.knownGene/") | |
560 | (synopsis "Annotation package for human genome in TxDb format") | |
561 | (description | |
562 | "This package provides an annotation database of Homo sapiens genome | |
563 | data. It is derived from the UCSC hg19 genome and based on the \"knownGene\" | |
798b80ce RW |
564 | track. The database is exposed as a @code{TxDb} object.") |
565 | (license license:artistic2.0))) | |
566 | ||
567 | (define-public r-txdb-hsapiens-ucsc-hg38-knowngene | |
568 | (package | |
569 | (name "r-txdb-hsapiens-ucsc-hg38-knowngene") | |
570 | (version "3.4.6") | |
571 | (source (origin | |
572 | (method url-fetch) | |
d78db088 RW |
573 | (uri (bioconductor-uri "TxDb.Hsapiens.UCSC.hg38.knownGene" |
574 | version 'annotation)) | |
798b80ce RW |
575 | (sha256 |
576 | (base32 | |
577 | "12j7rri9r129v9w1yiqadg952dx462dh092sxif3r5kk8l7bxkn9")))) | |
578 | (properties | |
579 | `((upstream-name . "TxDb.Hsapiens.UCSC.hg38.knownGene"))) | |
580 | (build-system r-build-system) | |
581 | (propagated-inputs | |
582 | `(("r-genomicfeatures" ,r-genomicfeatures))) | |
583 | (home-page | |
584 | "https://bioconductor.org/packages/TxDb.Hsapiens.UCSC.hg38.knownGene/") | |
585 | (synopsis "Annotation package for human genome in TxDb format") | |
586 | (description | |
587 | "This package provides an annotation database of Homo sapiens genome | |
588 | data. It is derived from the UCSC hg38 genome and based on the \"knownGene\" | |
66e35ce6 RW |
589 | track. The database is exposed as a @code{TxDb} object.") |
590 | (license license:artistic2.0))) | |
591 | ||
d220babf RW |
592 | (define-public r-txdb-mmusculus-ucsc-mm9-knowngene |
593 | (package | |
594 | (name "r-txdb-mmusculus-ucsc-mm9-knowngene") | |
595 | (version "3.2.2") | |
596 | (source (origin | |
597 | (method url-fetch) | |
1afdf41b RW |
598 | (uri (bioconductor-uri "TxDb.Mmusculus.UCSC.mm9.knownGene" |
599 | version 'annotation)) | |
d220babf RW |
600 | (sha256 |
601 | (base32 | |
602 | "16bjxy00363hf91ik2mqlqls86i07gia72qh92xc3l1ncch61mx2")))) | |
603 | (properties | |
604 | `((upstream-name . "TxDb.Mmusculus.UCSC.mm9.knownGene"))) | |
605 | (build-system r-build-system) | |
606 | (propagated-inputs | |
607 | `(("r-genomicfeatures" ,r-genomicfeatures) | |
608 | ("r-annotationdbi" ,r-annotationdbi))) | |
609 | (home-page | |
610 | "https://bioconductor.org/packages/TxDb.Mmusculus.UCSC.mm9.knownGene/") | |
611 | (synopsis "Annotation package for mouse genome in TxDb format") | |
612 | (description | |
613 | "This package provides an annotation database of Mouse genome data. It | |
614 | is derived from the UCSC mm9 genome and based on the \"knownGene\" track. The | |
615 | database is exposed as a @code{TxDb} object.") | |
616 | (license license:artistic2.0))) | |
617 | ||
7bc5d1b0 RW |
618 | (define-public r-txdb-mmusculus-ucsc-mm10-knowngene |
619 | (package | |
620 | (name "r-txdb-mmusculus-ucsc-mm10-knowngene") | |
b69c7703 | 621 | (version "3.10.0") |
7bc5d1b0 RW |
622 | (source (origin |
623 | (method url-fetch) | |
c271d990 RW |
624 | (uri (bioconductor-uri "TxDb.Mmusculus.UCSC.mm10.knownGene" |
625 | version 'annotation)) | |
7bc5d1b0 RW |
626 | (sha256 |
627 | (base32 | |
b69c7703 | 628 | "0xs9npnhbwll7p62hibs02y4ac23jchdcr25i6a7qwq1kms82qk9")))) |
7bc5d1b0 RW |
629 | (properties |
630 | `((upstream-name . "TxDb.Mmusculus.UCSC.mm10.knownGene"))) | |
631 | (build-system r-build-system) | |
7bc5d1b0 RW |
632 | (propagated-inputs |
633 | `(("r-bsgenome" ,r-bsgenome) | |
634 | ("r-genomicfeatures" ,r-genomicfeatures) | |
635 | ("r-annotationdbi" ,r-annotationdbi))) | |
636 | (home-page | |
637 | "https://bioconductor.org/packages/TxDb.Mmusculus.UCSC.mm10.knownGene/") | |
638 | (synopsis "Annotation package for TxDb knownGene object(s) for Mouse") | |
639 | (description | |
640 | "This package loads a TxDb object, which is an R interface to | |
641 | prefabricated databases contained in this package. This package provides | |
642 | the TxDb object of Mouse data as provided by UCSC (mm10, December 2011) | |
643 | based on the knownGene track.") | |
644 | (license license:artistic2.0))) | |
645 | ||
7cd446fd RW |
646 | (define-public r-txdb-celegans-ucsc-ce6-ensgene |
647 | (package | |
648 | (name "r-txdb-celegans-ucsc-ce6-ensgene") | |
649 | (version "3.2.2") | |
650 | (source | |
651 | (origin | |
652 | (method url-fetch) | |
653 | (uri (bioconductor-uri "TxDb.Celegans.UCSC.ce6.ensGene" | |
654 | version 'annotation)) | |
655 | (sha256 | |
656 | (base32 | |
657 | "1sgppva33cdy4isj2is8mfalj5gmmkpbkq9w1d83a4agcq31mi90")))) | |
658 | (properties | |
659 | `((upstream-name . "TxDb.Celegans.UCSC.ce6.ensGene"))) | |
660 | (build-system r-build-system) | |
661 | (propagated-inputs | |
662 | `(("r-annotationdbi" ,r-annotationdbi) | |
663 | ("r-genomicfeatures" ,r-genomicfeatures))) | |
664 | (home-page "https://bioconductor.org/packages/TxDb.Celegans.UCSC.ce6.ensGene/") | |
665 | (synopsis "Annotation package for C elegans TxDb objects") | |
666 | (description | |
667 | "This package exposes a C elegans annotation database generated from UCSC | |
668 | by exposing these as TxDb objects.") | |
669 | (license license:artistic2.0))) | |
670 | ||
0f5c9cec RW |
671 | (define-public r-fdb-infiniummethylation-hg19 |
672 | (package | |
673 | (name "r-fdb-infiniummethylation-hg19") | |
674 | (version "2.2.0") | |
675 | (source (origin | |
676 | (method url-fetch) | |
6aca4054 RW |
677 | (uri (bioconductor-uri "FDb.InfiniumMethylation.hg19" |
678 | version 'annotation)) | |
0f5c9cec RW |
679 | (sha256 |
680 | (base32 | |
681 | "0gq90fvph6kgrpjb89nvzq6hl1k24swn19rgjh5g98l86mja6nk0")))) | |
682 | (properties | |
683 | `((upstream-name . "FDb.InfiniumMethylation.hg19"))) | |
684 | (build-system r-build-system) | |
685 | (propagated-inputs | |
686 | `(("r-biostrings" ,r-biostrings) | |
687 | ("r-genomicfeatures" ,r-genomicfeatures) | |
688 | ("r-annotationdbi" ,r-annotationdbi) | |
689 | ("r-org-hs-eg-db" ,r-org-hs-eg-db) | |
690 | ("r-txdb-hsapiens-ucsc-hg19-knowngene" ,r-txdb-hsapiens-ucsc-hg19-knowngene))) | |
691 | (home-page "https://bioconductor.org/packages/FDb.InfiniumMethylation.hg19/") | |
692 | (synopsis "Compiled HumanMethylation27 and HumanMethylation450 annotations") | |
693 | (description | |
694 | "This is an annotation package for Illumina Infinium DNA methylation | |
695 | probes. It contains the compiled HumanMethylation27 and HumanMethylation450 | |
696 | annotations.") | |
697 | (license license:artistic2.0))) | |
698 | ||
9475a248 RW |
699 | (define-public r-illuminahumanmethylationepicmanifest |
700 | (package | |
701 | (name "r-illuminahumanmethylationepicmanifest") | |
702 | (version "0.3.0") | |
703 | (source (origin | |
704 | (method url-fetch) | |
25f567a8 RW |
705 | (uri (bioconductor-uri "IlluminaHumanMethylationEPICmanifest" |
706 | version 'annotation)) | |
9475a248 RW |
707 | (sha256 |
708 | (base32 | |
709 | "0alhjda5g186z8b1nsmnpfswrlj7prdz8mkwx60wkkl6hkcnk6p3")))) | |
710 | (properties | |
711 | `((upstream-name . "IlluminaHumanMethylationEPICmanifest"))) | |
712 | (build-system r-build-system) | |
713 | (propagated-inputs | |
714 | `(("r-minfi" ,r-minfi))) | |
715 | (home-page "https://bioconductor.org/packages/IlluminaHumanMethylationEPICmanifest/") | |
716 | (synopsis "Manifest for Illumina's EPIC methylation arrays") | |
717 | (description | |
718 | "This is a manifest package for Illumina's EPIC methylation arrays.") | |
719 | (license license:artistic2.0))) | |
720 | ||
a38bf7c8 RJ |
721 | ;; This is a CRAN package, but it depends on r-bsgenome-hsapiens-ucsc-hg19 |
722 | ;; from Bioconductor. | |
723 | (define-public r-deconstructsigs | |
724 | (package | |
725 | (name "r-deconstructsigs") | |
726 | (version "1.8.0") | |
727 | (source (origin | |
728 | (method url-fetch) | |
729 | (uri (cran-uri "deconstructSigs" version)) | |
730 | (sha256 | |
731 | (base32 | |
732 | "014x0nb23jb98666kaav2phkvmkr38pi38jv0dqd4jv7zp0gdf1a")))) | |
733 | (properties | |
734 | `((upstream-name . "deconstructSigs"))) | |
735 | (build-system r-build-system) | |
736 | (propagated-inputs | |
737 | `(("r-bsgenome" ,r-bsgenome) | |
738 | ("r-bsgenome-hsapiens-ucsc-hg19" ,r-bsgenome-hsapiens-ucsc-hg19) | |
739 | ("r-genomeinfodb" ,r-genomeinfodb) | |
740 | ("r-reshape2" ,r-reshape2))) | |
741 | (home-page "https://github.com/raerose01/deconstructSigs") | |
742 | (synopsis "Identifies signatures present in a tumor sample") | |
743 | (description "This package takes sample information in the form of the | |
744 | fraction of mutations in each of 96 trinucleotide contexts and identifies | |
745 | the weighted combination of published signatures that, when summed, most | |
746 | closely reconstructs the mutational profile.") | |
747 | (license license:gpl2+))) | |
748 | ||
7c9d8a5d RW |
749 | ;; This is a CRAN package, but it depends on Bioconductor packages. |
750 | (define-public r-nmf | |
751 | (package | |
752 | (name "r-nmf") | |
be1042b3 | 753 | (version "0.22.0") |
7c9d8a5d RW |
754 | (source |
755 | (origin | |
756 | (method url-fetch) | |
757 | (uri (cran-uri "NMF" version)) | |
758 | (sha256 | |
759 | (base32 | |
be1042b3 | 760 | "0b2ls3x1nkrnam45hagpys624nzxj3v7kxnp0q216yakvx5h57cq")))) |
7c9d8a5d RW |
761 | (properties `((upstream-name . "NMF"))) |
762 | (build-system r-build-system) | |
763 | (propagated-inputs | |
764 | `(("r-cluster" ,r-cluster) | |
be1042b3 RW |
765 | ("r-biobase" ,r-biobase) |
766 | ("r-biocmanager" ,r-biocmanager) | |
7c9d8a5d RW |
767 | ("r-bigmemory" ,r-bigmemory) ; suggested |
768 | ("r-synchronicity" ,r-synchronicity) ; suggested | |
769 | ("r-colorspace" ,r-colorspace) | |
770 | ("r-digest" ,r-digest) | |
771 | ("r-doparallel" ,r-doparallel) | |
772 | ("r-foreach" ,r-foreach) | |
773 | ("r-ggplot2" ,r-ggplot2) | |
774 | ("r-gridbase" ,r-gridbase) | |
775 | ("r-pkgmaker" ,r-pkgmaker) | |
776 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
777 | ("r-registry" ,r-registry) | |
778 | ("r-reshape2" ,r-reshape2) | |
779 | ("r-rngtools" ,r-rngtools) | |
780 | ("r-stringr" ,r-stringr))) | |
781 | (home-page "http://renozao.github.io/NMF") | |
782 | (synopsis "Algorithms and framework for nonnegative matrix factorization") | |
783 | (description | |
784 | "This package provides a framework to perform Non-negative Matrix | |
785 | Factorization (NMF). The package implements a set of already published | |
786 | algorithms and seeding methods, and provides a framework to test, develop and | |
787 | plug new or custom algorithms. Most of the built-in algorithms have been | |
788 | optimized in C++, and the main interface function provides an easy way of | |
789 | performing parallel computations on multicore machines.") | |
790 | (license license:gpl2+))) | |
791 | ||
f8a5af46 RW |
792 | (define-public r-do-db |
793 | (package | |
794 | (name "r-do-db") | |
795 | (version "2.9") | |
796 | (source (origin | |
797 | (method url-fetch) | |
eed2766a | 798 | (uri (bioconductor-uri "DO.db" version 'annotation)) |
f8a5af46 RW |
799 | (sha256 |
800 | (base32 | |
801 | "10bqqa124l61ivzy4mdd3z3ar9a6537qbxw23pc4y9w8a6dwnavn")))) | |
802 | (properties | |
803 | `((upstream-name . "DO.db"))) | |
804 | (build-system r-build-system) | |
805 | (propagated-inputs | |
806 | `(("r-annotationdbi" ,r-annotationdbi))) | |
807 | (home-page "https://www.bioconductor.org/packages/DO.db/") | |
808 | (synopsis "Annotation maps describing the entire Disease Ontology") | |
809 | (description | |
810 | "This package provides a set of annotation maps describing the entire | |
811 | Disease Ontology.") | |
812 | (license license:artistic2.0))) | |
813 | ||
83b42091 RW |
814 | (define-public r-pfam-db |
815 | (package | |
816 | (name "r-pfam-db") | |
817 | (version "3.8.2") | |
818 | (source | |
819 | (origin | |
820 | (method url-fetch) | |
821 | (uri (bioconductor-uri "PFAM.db" version 'annotation)) | |
822 | (sha256 | |
823 | (base32 | |
824 | "0rn1arzzcniy3yyc4yc44vn40g0cqss37dhwnvsgxpfayqq1k59s")))) | |
825 | (properties `((upstream-name . "PFAM.db"))) | |
826 | (build-system r-build-system) | |
827 | (propagated-inputs | |
828 | `(("r-annotationdbi" ,r-annotationdbi))) | |
829 | (home-page "https://bioconductor.org/packages/PFAM.db") | |
830 | (synopsis "Set of protein ID mappings for PFAM") | |
831 | (description | |
832 | "This package provides a set of protein ID mappings for PFAM, assembled | |
833 | using data from public repositories.") | |
834 | (license license:artistic2.0))) | |
835 | ||
40be965e RW |
836 | (define-public r-phastcons100way-ucsc-hg19 |
837 | (package | |
838 | (name "r-phastcons100way-ucsc-hg19") | |
839 | (version "3.7.2") | |
840 | (source | |
841 | (origin | |
842 | (method url-fetch) | |
843 | (uri (bioconductor-uri "phastCons100way.UCSC.hg19" | |
844 | version 'annotation)) | |
845 | (sha256 | |
846 | (base32 | |
847 | "1jmc4k4zgkx5vr2plnidnd9bidlwlb0kr7mjg60cqjw7dq7jl1fa")))) | |
848 | (properties | |
849 | `((upstream-name . "phastCons100way.UCSC.hg19"))) | |
850 | (build-system r-build-system) | |
851 | (propagated-inputs | |
852 | `(("r-bsgenome" ,r-bsgenome) | |
853 | ("r-genomeinfodb" ,r-genomeinfodb) | |
854 | ("r-genomicranges" ,r-genomicranges) | |
855 | ("r-genomicscores" ,r-genomicscores) | |
856 | ("r-iranges" ,r-iranges) | |
857 | ("r-s4vectors" ,r-s4vectors))) | |
858 | (home-page "https://bioconductor.org/packages/phastCons100way.UCSC.hg19") | |
859 | (synopsis "UCSC phastCons conservation scores for hg19") | |
860 | (description | |
861 | "This package provides UCSC phastCons conservation scores for the human | |
862 | genome (hg19) calculated from multiple alignments with other 99 vertebrate | |
863 | species.") | |
864 | (license license:artistic2.0))) | |
865 | ||
2cc51108 | 866 | \f |
557a1089 RW |
867 | ;;; Experiment data |
868 | ||
692bce15 RW |
869 | (define-public r-abadata |
870 | (package | |
871 | (name "r-abadata") | |
872 | (version "1.12.0") | |
873 | (source (origin | |
874 | (method url-fetch) | |
ced61edf | 875 | (uri (bioconductor-uri "ABAData" version 'experiment)) |
692bce15 RW |
876 | (sha256 |
877 | (base32 | |
878 | "1bmj341xcymlrk02gss5vvrqc4ddas0rdw39lnpsj98hq6n11p5z")))) | |
879 | (properties | |
880 | `((upstream-name . "ABAData"))) | |
881 | (build-system r-build-system) | |
882 | (propagated-inputs | |
883 | `(("r-annotationdbi" ,r-annotationdbi))) | |
884 | (home-page "https://www.bioconductor.org/packages/ABAData/") | |
885 | (synopsis "Gene expression in human brain regions from Allen Brain Atlas") | |
886 | (description | |
887 | "This package provides the data for the gene expression enrichment | |
888 | analysis conducted in the package ABAEnrichment. The package includes three | |
889 | datasets which are derived from the Allen Brain Atlas: | |
890 | ||
891 | @enumerate | |
892 | @item Gene expression data from Human Brain (adults) averaged across donors, | |
893 | @item Gene expression data from the Developing Human Brain pooled into five | |
894 | age categories and averaged across donors, and | |
895 | @item a developmental effect score based on the Developing Human Brain | |
896 | expression data. | |
897 | @end enumerate | |
898 | ||
899 | All datasets are restricted to protein coding genes.") | |
900 | (license license:gpl2+))) | |
901 | ||
b50c9660 RW |
902 | (define-public r-arrmdata |
903 | (package | |
904 | (name "r-arrmdata") | |
905 | (version "1.18.0") | |
906 | (source (origin | |
907 | (method url-fetch) | |
b86f7746 | 908 | (uri (bioconductor-uri "ARRmData" version 'experiment)) |
b50c9660 RW |
909 | (sha256 |
910 | (base32 | |
911 | "0r1y3zn7ly4k3ngx55vfavn9s6aidbddlv2fbmj7hj3hvpslmyly")))) | |
912 | (properties | |
913 | `((upstream-name . "ARRmData"))) | |
914 | (build-system r-build-system) | |
915 | (home-page "https://www.bioconductor.org/packages/ARRmData/") | |
916 | (synopsis "Example dataset for normalization of Illumina 450k methylation data") | |
917 | (description | |
918 | "This package provides raw beta values from 36 samples across 3 groups | |
919 | from Illumina 450k methylation arrays.") | |
920 | (license license:artistic2.0))) | |
921 | ||
557a1089 RW |
922 | (define-public r-hsmmsinglecell |
923 | (package | |
924 | (name "r-hsmmsinglecell") | |
925 | (version "1.2.0") | |
926 | (source (origin | |
927 | (method url-fetch) | |
545e67ac | 928 | (uri (bioconductor-uri "HSMMSingleCell" version 'experiment)) |
557a1089 RW |
929 | (sha256 |
930 | (base32 | |
931 | "1vxnr8gr6md85g39csy7g2sqqajiqgyvznys2qa9yixd2b01yph9")))) | |
932 | (properties | |
933 | `((upstream-name . "HSMMSingleCell"))) | |
934 | (build-system r-build-system) | |
935 | (home-page "https://www.bioconductor.org/packages/HSMMSingleCell/") | |
936 | (synopsis "Single-cell RNA-Seq for differentiating human skeletal muscle myoblasts (HSMM)") | |
937 | (description | |
938 | "Skeletal myoblasts undergo a well-characterized sequence of | |
939 | morphological and transcriptional changes during differentiation. In this | |
940 | experiment, primary @dfn{human skeletal muscle myoblasts} (HSMM) were expanded | |
941 | under high mitogen conditions (GM) and then differentiated by switching to | |
942 | low-mitogen media (DM). RNA-Seq libraries were sequenced from each of several | |
943 | hundred cells taken over a time-course of serum-induced differentiation. | |
944 | Between 49 and 77 cells were captured at each of four time points (0, 24, 48, | |
945 | 72 hours) following serum switch using the Fluidigm C1 microfluidic system. | |
946 | RNA from each cell was isolated and used to construct mRNA-Seq libraries, | |
947 | which were then sequenced to a depth of ~4 million reads per library, | |
948 | resulting in a complete gene expression profile for each cell.") | |
949 | (license license:artistic2.0))) | |
ad8f46c6 | 950 | |
951 | (define-public r-all | |
952 | (package | |
953 | (name "r-all") | |
954 | (version "1.26.0") | |
955 | (source (origin | |
956 | (method url-fetch) | |
41728d23 | 957 | (uri (bioconductor-uri "ALL" version 'experiment)) |
ad8f46c6 | 958 | (sha256 |
959 | (base32 | |
960 | "1z7kpjw4ndj6fkxwvhqf3gawhrn26ksrlns7j2c78qzxqmjndik9")))) | |
961 | (properties `((upstream-name . "ALL"))) | |
962 | (build-system r-build-system) | |
963 | (propagated-inputs | |
964 | `(("r-biobase" ,r-biobase))) | |
965 | (home-page "https://bioconductor.org/packages/ALL") | |
966 | (synopsis "Acute Lymphoblastic Leukemia data from the Ritz laboratory") | |
967 | (description | |
968 | "The data consist of microarrays from 128 different individuals with | |
969 | @dfn{acute lymphoblastic leukemia} (ALL). A number of additional covariates | |
970 | are available. The data have been normalized (using rma) and it is the | |
971 | jointly normalized data that are available here. The data are presented in | |
972 | the form of an @code{exprSet} object.") | |
973 | (license license:artistic2.0))) | |
557a1089 | 974 | |
53b1e10f RW |
975 | (define-public r-affydata |
976 | (package | |
977 | (name "r-affydata") | |
978 | (version "1.32.0") | |
979 | (source | |
980 | (origin | |
981 | (method url-fetch) | |
982 | (uri (bioconductor-uri "affydata" version 'experiment)) | |
983 | (sha256 | |
984 | (base32 | |
985 | "1l9qhmjqgbrdl9cmd74rlnvmvr6mslbmckb83n0211whp2i0b7h5")))) | |
986 | (properties `((upstream-name . "affydata"))) | |
987 | (build-system r-build-system) | |
988 | (propagated-inputs | |
989 | `(("r-affy" ,r-affy))) | |
990 | (home-page "https://bioconductor.org/packages/affydata/") | |
991 | (synopsis "Affymetrix data for demonstration purposes") | |
992 | (description | |
993 | "This package provides example datasets that represent 'real world | |
994 | examples' of Affymetrix data, unlike the artificial examples included in the | |
995 | package @code{affy}.") | |
996 | (license license:gpl2+))) | |
997 | ||
ff1146b9 RW |
998 | (define-public r-curatedtcgadata |
999 | (package | |
1000 | (name "r-curatedtcgadata") | |
1001 | (version "1.8.0") | |
1002 | (source | |
1003 | (origin | |
1004 | (method url-fetch) | |
1005 | (uri (bioconductor-uri "curatedTCGAData" version 'experiment)) | |
1006 | (sha256 | |
1007 | (base32 | |
1008 | "02y6cgihmsl9b4a9mmcdjjgjp06lpz04biyvxd3n5lk5gnqd9r3y")))) | |
1009 | (properties | |
1010 | `((upstream-name . "curatedTCGAData"))) | |
1011 | (build-system r-build-system) | |
1012 | (propagated-inputs | |
1013 | `(("r-annotationhub" ,r-annotationhub) | |
1014 | ("r-experimenthub" ,r-experimenthub) | |
1015 | ("r-hdf5array" ,r-hdf5array) | |
1016 | ("r-multiassayexperiment" ,r-multiassayexperiment) | |
1017 | ("r-s4vectors" ,r-s4vectors) | |
1018 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
1019 | (home-page "https://bioconductor.org/packages/curatedTCGAData/") | |
1020 | (synopsis "Curated data from The Cancer Genome Atlas") | |
1021 | (description | |
1022 | "This package provides publicly available data from The Cancer Genome | |
1023 | Atlas (TCGA) as @code{MultiAssayExperiment} objects. | |
1024 | @code{MultiAssayExperiment} integrates multiple assays (e.g., RNA-seq, copy | |
1025 | number, mutation, microRNA, protein, and others) with clinical / pathological | |
1026 | data. It also links assay barcodes with patient identifiers, enabling | |
1027 | harmonized subsetting of rows (features) and columns (patients / samples) | |
1028 | across the entire multi-'omics experiment.") | |
1029 | (license license:artistic2.0))) | |
1030 | ||
557a1089 RW |
1031 | \f |
1032 | ;;; Packages | |
1033 | ||
e5d722fb RW |
1034 | (define-public r-biocversion |
1035 | (package | |
1036 | (name "r-biocversion") | |
1037 | (version "3.10.1") | |
1038 | (source | |
1039 | (origin | |
1040 | (method url-fetch) | |
1041 | (uri (bioconductor-uri "BiocVersion" version)) | |
1042 | (sha256 | |
1043 | (base32 | |
1044 | "0mfqjqfvrwwglldq3g7nbic5hf3nwzv02nbfxnl2cfvf9gznlh5f")))) | |
1045 | (properties `((upstream-name . "BiocVersion"))) | |
1046 | (build-system r-build-system) | |
1047 | (home-page "https://bioconductor.org/packages/BiocVersion/") | |
1048 | (synopsis "Set the appropriate version of Bioconductor packages") | |
1049 | (description | |
1050 | "This package provides repository information for the appropriate version | |
1051 | of Bioconductor.") | |
1052 | (license license:artistic2.0))) | |
1053 | ||
14bba460 RW |
1054 | (define-public r-biocgenerics |
1055 | (package | |
1056 | (name "r-biocgenerics") | |
be5e4e96 | 1057 | (version "0.32.0") |
14bba460 RW |
1058 | (source (origin |
1059 | (method url-fetch) | |
1060 | (uri (bioconductor-uri "BiocGenerics" version)) | |
1061 | (sha256 | |
1062 | (base32 | |
be5e4e96 | 1063 | "1np8y442zyakm4axpinbw1qsgc6wd3zjsnirbhc8lcii4ky9j0rn")))) |
14bba460 RW |
1064 | (properties |
1065 | `((upstream-name . "BiocGenerics"))) | |
1066 | (build-system r-build-system) | |
1067 | (home-page "https://bioconductor.org/packages/BiocGenerics") | |
1068 | (synopsis "S4 generic functions for Bioconductor") | |
1069 | (description | |
1070 | "This package provides S4 generic functions needed by many Bioconductor | |
1071 | packages.") | |
1072 | (license license:artistic2.0))) | |
1073 | ||
5cf940de RW |
1074 | (define-public r-affycomp |
1075 | (package | |
1076 | (name "r-affycomp") | |
5d87f126 | 1077 | (version "1.62.0") |
5cf940de RW |
1078 | (source |
1079 | (origin | |
1080 | (method url-fetch) | |
1081 | (uri (bioconductor-uri "affycomp" version)) | |
1082 | (sha256 | |
1083 | (base32 | |
5d87f126 | 1084 | "0cl7c3m2lz2w8g2k7z7wjd0dyj0dkssvms99qpg8a1v3hx1xs6js")))) |
5cf940de RW |
1085 | (properties `((upstream-name . "affycomp"))) |
1086 | (build-system r-build-system) | |
1087 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
1088 | (home-page "https://bioconductor.org/packages/affycomp/") | |
1089 | (synopsis "Graphics toolbox for assessment of Affymetrix expression measures") | |
1090 | (description | |
1091 | "The package contains functions that can be used to compare expression | |
1092 | measures for Affymetrix Oligonucleotide Arrays.") | |
1093 | (license license:gpl2+))) | |
1094 | ||
5094aa94 RW |
1095 | (define-public r-affycompatible |
1096 | (package | |
1097 | (name "r-affycompatible") | |
c2fa63e9 | 1098 | (version "1.46.0") |
5094aa94 RW |
1099 | (source |
1100 | (origin | |
1101 | (method url-fetch) | |
1102 | (uri (bioconductor-uri "AffyCompatible" version)) | |
1103 | (sha256 | |
1104 | (base32 | |
c2fa63e9 | 1105 | "10ahrdlifp1i7rd58zb10w75y5bnigs7xp5gv4fhb5y7p7dvb0ks")))) |
5094aa94 RW |
1106 | (properties |
1107 | `((upstream-name . "AffyCompatible"))) | |
1108 | (build-system r-build-system) | |
1109 | (propagated-inputs | |
1110 | `(("r-biostrings" ,r-biostrings) | |
1111 | ("r-rcurl" ,r-rcurl) | |
1112 | ("r-xml" ,r-xml))) | |
1113 | (home-page "https://bioconductor.org/packages/AffyCompatible/") | |
1114 | (synopsis "Work with Affymetrix GeneChip files") | |
1115 | (description | |
1116 | "This package provides an interface to Affymetrix chip annotation and | |
1117 | sample attribute files. The package allows an easy way for users to download | |
1118 | and manage local data bases of Affynmetrix NetAffx annotation files. It also | |
1119 | provides access to @dfn{GeneChip Operating System} (GCOS) and @dfn{GeneChip | |
1120 | Command Console} (AGCC)-compatible sample annotation files.") | |
1121 | (license license:artistic2.0))) | |
1122 | ||
4ca2d6c1 RW |
1123 | (define-public r-affycontam |
1124 | (package | |
1125 | (name "r-affycontam") | |
f561421d | 1126 | (version "1.44.0") |
4ca2d6c1 RW |
1127 | (source |
1128 | (origin | |
1129 | (method url-fetch) | |
1130 | (uri (bioconductor-uri "affyContam" version)) | |
1131 | (sha256 | |
1132 | (base32 | |
f561421d | 1133 | "0yd1prgv5zfkg22ski73mvg96qknwz8v6ji6s4qy8p4wrqyj7b7l")))) |
4ca2d6c1 RW |
1134 | (properties `((upstream-name . "affyContam"))) |
1135 | (build-system r-build-system) | |
1136 | (propagated-inputs | |
1137 | `(("r-affy" ,r-affy) | |
1138 | ("r-affydata" ,r-affydata) | |
1139 | ("r-biobase" ,r-biobase))) | |
1140 | (home-page "https://bioconductor.org/packages/affyContam/") | |
1141 | (synopsis "Structured corruption of Affymetrix CEL file data") | |
1142 | (description | |
1143 | "Microarray quality assessment is a major concern of microarray analysts. | |
1144 | This package provides some simple approaches to in silico creation of quality | |
1145 | problems in CEL-level data to help evaluate performance of quality metrics.") | |
1146 | (license license:artistic2.0))) | |
1147 | ||
12105c6c RW |
1148 | (define-public r-affycoretools |
1149 | (package | |
1150 | (name "r-affycoretools") | |
f8f181ae | 1151 | (version "1.58.4") |
12105c6c RW |
1152 | (source |
1153 | (origin | |
1154 | (method url-fetch) | |
1155 | (uri (bioconductor-uri "affycoretools" version)) | |
1156 | (sha256 | |
1157 | (base32 | |
f8f181ae | 1158 | "1p283ysib04qzaayxmrpsmk5bq0jdq2rlky180jrlskpyg6risfw")))) |
12105c6c RW |
1159 | (properties `((upstream-name . "affycoretools"))) |
1160 | (build-system r-build-system) | |
1161 | (propagated-inputs | |
1162 | `(("r-affy" ,r-affy) | |
1163 | ("r-annotationdbi" ,r-annotationdbi) | |
1164 | ("r-biobase" ,r-biobase) | |
1165 | ("r-biocgenerics" ,r-biocgenerics) | |
1166 | ("r-dbi" ,r-dbi) | |
1167 | ("r-edger" ,r-edger) | |
1168 | ("r-gcrma" ,r-gcrma) | |
f8f181ae | 1169 | ("r-glimma" ,r-glimma) |
12105c6c RW |
1170 | ("r-ggplot2" ,r-ggplot2) |
1171 | ("r-gostats" ,r-gostats) | |
1172 | ("r-gplots" ,r-gplots) | |
1173 | ("r-hwriter" ,r-hwriter) | |
1174 | ("r-lattice" ,r-lattice) | |
1175 | ("r-limma" ,r-limma) | |
1176 | ("r-oligoclasses" ,r-oligoclasses) | |
1177 | ("r-reportingtools" ,r-reportingtools) | |
1178 | ("r-rsqlite" ,r-rsqlite) | |
1179 | ("r-s4vectors" ,r-s4vectors) | |
1180 | ("r-xtable" ,r-xtable))) | |
1181 | (home-page "https://bioconductor.org/packages/affycoretools/") | |
1182 | (synopsis "Functions for analyses with Affymetrix GeneChips") | |
1183 | (description | |
1184 | "This package provides various wrapper functions that have been written | |
1185 | to streamline the more common analyses that a Biostatistician might see.") | |
1186 | (license license:artistic2.0))) | |
1187 | ||
d6a5d9b2 RW |
1188 | (define-public r-affxparser |
1189 | (package | |
1190 | (name "r-affxparser") | |
ce5162d0 | 1191 | (version "1.58.0") |
d6a5d9b2 RW |
1192 | (source |
1193 | (origin | |
1194 | (method url-fetch) | |
1195 | (uri (bioconductor-uri "affxparser" version)) | |
1196 | (sha256 | |
1197 | (base32 | |
ce5162d0 | 1198 | "03h4lxr48p84f6i7zb2rm10ma3k4d1nmvdw5yhxcmzqbmd12lk40")))) |
d6a5d9b2 RW |
1199 | (properties `((upstream-name . "affxparser"))) |
1200 | (build-system r-build-system) | |
1201 | (home-page "https://github.com/HenrikBengtsson/affxparser") | |
1202 | (synopsis "Affymetrix File Parsing SDK") | |
1203 | (description | |
1204 | "This is a package for parsing Affymetrix files (CDF, CEL, CHP, BPMAP, | |
1205 | BAR). It provides methods for fast and memory efficient parsing of Affymetrix | |
1206 | files using the Affymetrix' Fusion SDK. Both ASCII- and binary-based files | |
1207 | are supported. Currently, there are methods for reading @dfn{chip definition | |
1208 | file} (CDF) and a @dfn{cell intensity file} (CEL). These files can be read | |
1209 | either in full or in part. For example, probe signals from a few probesets | |
1210 | can be extracted very quickly from a set of CEL files into a convenient list | |
1211 | structure.") | |
1212 | ;; The Fusion SDK contains files under GPLv2 and LGPLv2.1. The R code is | |
1213 | ;; under LGPLv2+. | |
1214 | (license (list license:lgpl2.0+ license:lgpl2.1 license:gpl2)))) | |
1215 | ||
7097c700 RW |
1216 | (define-public r-annotate |
1217 | (package | |
1218 | (name "r-annotate") | |
7a111924 | 1219 | (version "1.64.0") |
7097c700 RW |
1220 | (source |
1221 | (origin | |
1222 | (method url-fetch) | |
1223 | (uri (bioconductor-uri "annotate" version)) | |
1224 | (sha256 | |
1225 | (base32 | |
7a111924 | 1226 | "0rcmdy6hs6m4d6wxgi52c0bhdsbf2sm9f155qbcb05sn0nh8pxwy")))) |
7097c700 RW |
1227 | (build-system r-build-system) |
1228 | (propagated-inputs | |
1229 | `(("r-annotationdbi" ,r-annotationdbi) | |
1230 | ("r-biobase" ,r-biobase) | |
1231 | ("r-biocgenerics" ,r-biocgenerics) | |
1232 | ("r-dbi" ,r-dbi) | |
1233 | ("r-rcurl" ,r-rcurl) | |
1234 | ("r-xml" ,r-xml) | |
1235 | ("r-xtable" ,r-xtable))) | |
1236 | (home-page | |
1237 | "https://bioconductor.org/packages/annotate") | |
1238 | (synopsis "Annotation for microarrays") | |
1239 | (description "This package provides R environments for the annotation of | |
1240 | microarrays.") | |
1241 | (license license:artistic2.0))) | |
1242 | ||
fa596599 RW |
1243 | (define-public r-hpar |
1244 | (package | |
1245 | (name "r-hpar") | |
ddd36739 | 1246 | (version "1.28.0") |
fa596599 RW |
1247 | (source |
1248 | (origin | |
1249 | (method url-fetch) | |
1250 | (uri (bioconductor-uri "hpar" version)) | |
1251 | (sha256 | |
1252 | (base32 | |
ddd36739 | 1253 | "1yhay1ryrgj9cqa1x136cw40ca93afyvg0sarm30jsbj8nc1rm5m")))) |
fa596599 RW |
1254 | (build-system r-build-system) |
1255 | (home-page "https://bioconductor.org/packages/hpar/") | |
1256 | (synopsis "Human Protein Atlas in R") | |
1257 | (description "This package provides a simple interface to and data from | |
1258 | the Human Protein Atlas project.") | |
1259 | (license license:artistic2.0))) | |
183ce988 RJ |
1260 | |
1261 | (define-public r-regioner | |
1262 | (package | |
1263 | (name "r-regioner") | |
7a8fcdac | 1264 | (version "1.18.1") |
183ce988 RJ |
1265 | (source |
1266 | (origin | |
1267 | (method url-fetch) | |
1268 | (uri (bioconductor-uri "regioneR" version)) | |
1269 | (sha256 | |
1270 | (base32 | |
7a8fcdac | 1271 | "0if7r6njz3ahm545383z5mzmzw8fdvw80a9lfz160j5pcgpx2dq9")))) |
183ce988 RJ |
1272 | (properties `((upstream-name . "regioneR"))) |
1273 | (build-system r-build-system) | |
1274 | (propagated-inputs | |
d639d888 | 1275 | `(("r-biostrings" ,r-biostrings) |
183ce988 | 1276 | ("r-bsgenome" ,r-bsgenome) |
183ce988 | 1277 | ("r-genomeinfodb" ,r-genomeinfodb) |
d639d888 | 1278 | ("r-genomicranges" ,r-genomicranges) |
72427c72 | 1279 | ("r-iranges" ,r-iranges) |
d639d888 RW |
1280 | ("r-memoise" ,r-memoise) |
1281 | ("r-rtracklayer" ,r-rtracklayer) | |
72427c72 | 1282 | ("r-s4vectors" ,r-s4vectors))) |
183ce988 RJ |
1283 | (home-page "https://bioconductor.org/packages/regioneR/") |
1284 | (synopsis "Association analysis of genomic regions") | |
1285 | (description "This package offers a statistical framework based on | |
1286 | customizable permutation tests to assess the association between genomic | |
1287 | region sets and other genomic features.") | |
1288 | (license license:artistic2.0))) | |
a5b56a53 | 1289 | |
15184fb3 RW |
1290 | (define-public r-reportingtools |
1291 | (package | |
1292 | (name "r-reportingtools") | |
7ccbaf1b | 1293 | (version "2.26.0") |
15184fb3 RW |
1294 | (source |
1295 | (origin | |
1296 | (method url-fetch) | |
1297 | (uri (bioconductor-uri "ReportingTools" version)) | |
1298 | (sha256 | |
1299 | (base32 | |
7ccbaf1b | 1300 | "0wmi2219wydyzc07rz3azsrksa7wiacfh9pr5x2fsmj9f0w3n15w")))) |
15184fb3 RW |
1301 | (properties |
1302 | `((upstream-name . "ReportingTools"))) | |
1303 | (build-system r-build-system) | |
1304 | (propagated-inputs | |
1305 | `(("r-annotate" ,r-annotate) | |
1306 | ("r-annotationdbi" ,r-annotationdbi) | |
1307 | ("r-biobase" ,r-biobase) | |
1308 | ("r-biocgenerics" ,r-biocgenerics) | |
1309 | ("r-category" ,r-category) | |
1310 | ("r-deseq2" ,r-deseq2) | |
1311 | ("r-edger" ,r-edger) | |
1312 | ("r-ggbio" ,r-ggbio) | |
1313 | ("r-ggplot2" ,r-ggplot2) | |
1314 | ("r-gostats" ,r-gostats) | |
1315 | ("r-gseabase" ,r-gseabase) | |
1316 | ("r-hwriter" ,r-hwriter) | |
1317 | ("r-iranges" ,r-iranges) | |
1318 | ("r-knitr" ,r-knitr) | |
1319 | ("r-lattice" ,r-lattice) | |
1320 | ("r-limma" ,r-limma) | |
1321 | ("r-pfam-db" ,r-pfam-db) | |
1322 | ("r-r-utils" ,r-r-utils) | |
1323 | ("r-xml" ,r-xml))) | |
1324 | (home-page "https://bioconductor.org/packages/ReportingTools/") | |
1325 | (synopsis "Tools for making reports in various formats") | |
1326 | (description | |
1327 | "The ReportingTools package enables users to easily display reports of | |
1328 | analysis results generated from sources such as microarray and sequencing | |
1329 | data. The package allows users to create HTML pages that may be viewed on a | |
1330 | web browser, or in other formats. Users can generate tables with sortable and | |
1331 | filterable columns, make and display plots, and link table entries to other | |
1332 | data sources such as NCBI or larger plots within the HTML page. Using the | |
1333 | package, users can also produce a table of contents page to link various | |
1334 | reports together for a particular project that can be viewed in a web | |
1335 | browser.") | |
1336 | (license license:artistic2.0))) | |
1337 | ||
bfb93b48 RW |
1338 | (define-public r-geneplotter |
1339 | (package | |
1340 | (name "r-geneplotter") | |
7778e91a | 1341 | (version "1.64.0") |
bfb93b48 RW |
1342 | (source |
1343 | (origin | |
1344 | (method url-fetch) | |
1345 | (uri (bioconductor-uri "geneplotter" version)) | |
1346 | (sha256 | |
1347 | (base32 | |
7778e91a | 1348 | "1k6780fn1kkghpm1prhhsyw621441a3bmnqfl9ns0zbc1zdq39nx")))) |
bfb93b48 RW |
1349 | (build-system r-build-system) |
1350 | (propagated-inputs | |
1351 | `(("r-annotate" ,r-annotate) | |
1352 | ("r-annotationdbi" ,r-annotationdbi) | |
1353 | ("r-biobase" ,r-biobase) | |
1354 | ("r-biocgenerics" ,r-biocgenerics) | |
1355 | ("r-lattice" ,r-lattice) | |
1356 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
1357 | (home-page "https://bioconductor.org/packages/geneplotter") | |
1358 | (synopsis "Graphics functions for genomic data") | |
1359 | (description | |
1360 | "This package provides functions for plotting genomic data.") | |
1361 | (license license:artistic2.0))) | |
1362 | ||
01c7ba99 RW |
1363 | (define-public r-oligoclasses |
1364 | (package | |
1365 | (name "r-oligoclasses") | |
79820b9f | 1366 | (version "1.48.0") |
01c7ba99 RW |
1367 | (source |
1368 | (origin | |
1369 | (method url-fetch) | |
1370 | (uri (bioconductor-uri "oligoClasses" version)) | |
1371 | (sha256 | |
1372 | (base32 | |
79820b9f | 1373 | "02m1m3dkiyywalphw3i5n6y3bs8zp24xh59v9cz6jgjpah811skf")))) |
01c7ba99 RW |
1374 | (properties `((upstream-name . "oligoClasses"))) |
1375 | (build-system r-build-system) | |
1376 | (propagated-inputs | |
1377 | `(("r-affyio" ,r-affyio) | |
1378 | ("r-biobase" ,r-biobase) | |
1379 | ("r-biocgenerics" ,r-biocgenerics) | |
1380 | ("r-biocmanager" ,r-biocmanager) | |
1381 | ("r-biostrings" ,r-biostrings) | |
1382 | ("r-dbi" ,r-dbi) | |
1383 | ("r-ff" ,r-ff) | |
1384 | ("r-foreach" ,r-foreach) | |
1385 | ("r-genomicranges" ,r-genomicranges) | |
1386 | ("r-iranges" ,r-iranges) | |
1387 | ("r-rsqlite" ,r-rsqlite) | |
1388 | ("r-s4vectors" ,r-s4vectors) | |
1389 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
1390 | (home-page "https://bioconductor.org/packages/oligoClasses/") | |
1391 | (synopsis "Classes for high-throughput arrays") | |
1392 | (description | |
1393 | "This package contains class definitions, validity checks, and | |
1394 | initialization methods for classes used by the @code{oligo} and @code{crlmm} | |
1395 | packages.") | |
1396 | (license license:gpl2+))) | |
1397 | ||
4c63eeb8 RW |
1398 | (define-public r-oligo |
1399 | (package | |
1400 | (name "r-oligo") | |
084c651c | 1401 | (version "1.50.0") |
4c63eeb8 RW |
1402 | (source |
1403 | (origin | |
1404 | (method url-fetch) | |
1405 | (uri (bioconductor-uri "oligo" version)) | |
1406 | (sha256 | |
1407 | (base32 | |
084c651c | 1408 | "01icfyy82f9k0m7ngrppz1ckq3wpq7zp6kgf8ppc55j6582c5jh3")))) |
4c63eeb8 RW |
1409 | (properties `((upstream-name . "oligo"))) |
1410 | (build-system r-build-system) | |
1411 | (inputs `(("zlib" ,zlib))) | |
1412 | (propagated-inputs | |
1413 | `(("r-affxparser" ,r-affxparser) | |
1414 | ("r-affyio" ,r-affyio) | |
1415 | ("r-biobase" ,r-biobase) | |
1416 | ("r-biocgenerics" ,r-biocgenerics) | |
1417 | ("r-biostrings" ,r-biostrings) | |
1418 | ("r-dbi" ,r-dbi) | |
1419 | ("r-ff" ,r-ff) | |
1420 | ("r-oligoclasses" ,r-oligoclasses) | |
1421 | ("r-preprocesscore" ,r-preprocesscore) | |
1422 | ("r-rsqlite" ,r-rsqlite) | |
1423 | ("r-zlibbioc" ,r-zlibbioc))) | |
1424 | (home-page "https://bioconductor.org/packages/oligo/") | |
1425 | (synopsis "Preprocessing tools for oligonucleotide arrays") | |
1426 | (description | |
1427 | "This package provides a package to analyze oligonucleotide | |
1428 | arrays (expression/SNP/tiling/exon) at probe-level. It currently supports | |
1429 | Affymetrix (CEL files) and NimbleGen arrays (XYS files).") | |
1430 | (license license:lgpl2.0+))) | |
1431 | ||
4dc2ecc2 RW |
1432 | (define-public r-qvalue |
1433 | (package | |
1434 | (name "r-qvalue") | |
bcf711b5 | 1435 | (version "2.18.0") |
4dc2ecc2 RW |
1436 | (source |
1437 | (origin | |
1438 | (method url-fetch) | |
1439 | (uri (bioconductor-uri "qvalue" version)) | |
1440 | (sha256 | |
1441 | (base32 | |
bcf711b5 | 1442 | "0njnidyncm3g3712mnp77cs4kghn596ss1pz6fhp1cr0wxcayp6j")))) |
4dc2ecc2 RW |
1443 | (build-system r-build-system) |
1444 | (propagated-inputs | |
1445 | `(("r-ggplot2" ,r-ggplot2) | |
1446 | ("r-reshape2" ,r-reshape2))) | |
1447 | (home-page "http://github.com/jdstorey/qvalue") | |
1448 | (synopsis "Q-value estimation for false discovery rate control") | |
1449 | (description | |
1450 | "This package takes a list of p-values resulting from the simultaneous | |
1451 | testing of many hypotheses and estimates their q-values and local @dfn{false | |
1452 | discovery rate} (FDR) values. The q-value of a test measures the proportion | |
1453 | of false positives incurred when that particular test is called significant. | |
1454 | The local FDR measures the posterior probability the null hypothesis is true | |
1455 | given the test's p-value. Various plots are automatically generated, allowing | |
1456 | one to make sensible significance cut-offs. The software can be applied to | |
1457 | problems in genomics, brain imaging, astrophysics, and data mining.") | |
1458 | ;; Any version of the LGPL. | |
1459 | (license license:lgpl3+))) | |
1460 | ||
a5b56a53 RJ |
1461 | (define-public r-diffbind |
1462 | (package | |
1463 | (name "r-diffbind") | |
73883f0f | 1464 | (version "2.14.0") |
a5b56a53 RJ |
1465 | (source |
1466 | (origin | |
1467 | (method url-fetch) | |
1468 | (uri (bioconductor-uri "DiffBind" version)) | |
1469 | (sha256 | |
1470 | (base32 | |
73883f0f | 1471 | "1729wyi2l4480yrkp5wg3ryirrmlk0j3njqs1qyckq3c8bjk12h2")))) |
a5b56a53 RJ |
1472 | (properties `((upstream-name . "DiffBind"))) |
1473 | (build-system r-build-system) | |
1474 | (inputs | |
1475 | `(("zlib" ,zlib))) | |
1476 | (propagated-inputs | |
1477 | `(("r-amap" ,r-amap) | |
1478 | ("r-biocparallel" ,r-biocparallel) | |
1479 | ("r-deseq2" ,r-deseq2) | |
1480 | ("r-dplyr" ,r-dplyr) | |
1481 | ("r-edger" ,r-edger) | |
1482 | ("r-genomicalignments" ,r-genomicalignments) | |
45bbccf4 RW |
1483 | ("r-genomicranges" ,r-genomicranges) |
1484 | ("r-ggplot2" ,r-ggplot2) | |
a5b56a53 RJ |
1485 | ("r-ggrepel" ,r-ggrepel) |
1486 | ("r-gplots" ,r-gplots) | |
1487 | ("r-iranges" ,r-iranges) | |
1488 | ("r-lattice" ,r-lattice) | |
1489 | ("r-limma" ,r-limma) | |
1490 | ("r-locfit" ,r-locfit) | |
1491 | ("r-rcolorbrewer" , r-rcolorbrewer) | |
1492 | ("r-rcpp" ,r-rcpp) | |
4c221b3b | 1493 | ("r-rhtslib" ,r-rhtslib) |
a5b56a53 RJ |
1494 | ("r-rsamtools" ,r-rsamtools) |
1495 | ("r-s4vectors" ,r-s4vectors) | |
45bbccf4 | 1496 | ("r-summarizedexperiment" ,r-summarizedexperiment) |
4c221b3b | 1497 | ("r-systempiper" ,r-systempiper))) |
99db6db7 | 1498 | (home-page "https://bioconductor.org/packages/DiffBind") |
a5b56a53 RJ |
1499 | (synopsis "Differential binding analysis of ChIP-Seq peak data") |
1500 | (description | |
1501 | "This package computes differentially bound sites from multiple | |
1502 | ChIP-seq experiments using affinity (quantitative) data. Also enables | |
1503 | occupancy (overlap) analysis and plotting functions.") | |
1504 | (license license:artistic2.0))) | |
6d94bf6b RJ |
1505 | |
1506 | (define-public r-ripseeker | |
1507 | (package | |
1508 | (name "r-ripseeker") | |
ba74434f | 1509 | (version "1.26.0") |
6d94bf6b RJ |
1510 | (source |
1511 | (origin | |
1512 | (method url-fetch) | |
1513 | (uri (bioconductor-uri "RIPSeeker" version)) | |
1514 | (sha256 | |
1515 | (base32 | |
ba74434f | 1516 | "1wyv9mfrbxzklysfjcnwb8yils71janyyxa982jn0zxx4p9cl3vs")))) |
6d94bf6b RJ |
1517 | (properties `((upstream-name . "RIPSeeker"))) |
1518 | (build-system r-build-system) | |
1519 | (propagated-inputs | |
1520 | `(("r-s4vectors" ,r-s4vectors) | |
1521 | ("r-iranges" ,r-iranges) | |
1522 | ("r-genomicranges" ,r-genomicranges) | |
1523 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
1524 | ("r-rsamtools" ,r-rsamtools) | |
1525 | ("r-genomicalignments" ,r-genomicalignments) | |
1526 | ("r-rtracklayer" ,r-rtracklayer))) | |
99db6db7 | 1527 | (home-page "https://bioconductor.org/packages/RIPSeeker") |
6d94bf6b RJ |
1528 | (synopsis |
1529 | "Identifying protein-associated transcripts from RIP-seq experiments") | |
1530 | (description | |
1531 | "This package infers and discriminates RIP peaks from RIP-seq alignments | |
1532 | using two-state HMM with negative binomial emission probability. While | |
1533 | RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides | |
1534 | a suite of bioinformatics tools integrated within this self-contained software | |
1535 | package comprehensively addressing issues ranging from post-alignments | |
1536 | processing to visualization and annotation.") | |
1537 | (license license:gpl2))) | |
a6ae9ffd RJ |
1538 | |
1539 | (define-public r-multtest | |
1540 | (package | |
1541 | (name "r-multtest") | |
16d49c2a | 1542 | (version "2.42.0") |
a6ae9ffd RJ |
1543 | (source |
1544 | (origin | |
1545 | (method url-fetch) | |
1546 | (uri (bioconductor-uri "multtest" version)) | |
1547 | (sha256 | |
1548 | (base32 | |
16d49c2a | 1549 | "0qna9lx76ldsfy8qf5xmhl4ymqfkj29m1gdqhph06s470c8mwari")))) |
a6ae9ffd RJ |
1550 | (build-system r-build-system) |
1551 | (propagated-inputs | |
1552 | `(("r-survival" ,r-survival) | |
1553 | ("r-biocgenerics" ,r-biocgenerics) | |
1554 | ("r-biobase" ,r-biobase) | |
1555 | ("r-mass" ,r-mass))) | |
99db6db7 | 1556 | (home-page "https://bioconductor.org/packages/multtest") |
a6ae9ffd RJ |
1557 | (synopsis "Resampling-based multiple hypothesis testing") |
1558 | (description | |
1559 | "This package can do non-parametric bootstrap and permutation | |
1560 | resampling-based multiple testing procedures (including empirical Bayes | |
1561 | methods) for controlling the family-wise error rate (FWER), generalized | |
1562 | family-wise error rate (gFWER), tail probability of the proportion of | |
1563 | false positives (TPPFP), and false discovery rate (FDR). Several choices | |
1564 | of bootstrap-based null distribution are implemented (centered, centered | |
1565 | and scaled, quantile-transformed). Single-step and step-wise methods are | |
1566 | available. Tests based on a variety of T- and F-statistics (including | |
1567 | T-statistics based on regression parameters from linear and survival models | |
1568 | as well as those based on correlation parameters) are included. When probing | |
1569 | hypotheses with T-statistics, users may also select a potentially faster null | |
1570 | distribution which is multivariate normal with mean zero and variance | |
1571 | covariance matrix derived from the vector influence function. Results are | |
1572 | reported in terms of adjusted P-values, confidence regions and test statistic | |
1573 | cutoffs. The procedures are directly applicable to identifying differentially | |
1574 | expressed genes in DNA microarray experiments.") | |
1575 | (license license:lgpl3))) | |
793f83ef | 1576 | |
5dfe4912 RW |
1577 | (define-public r-graph |
1578 | (package | |
1579 | (name "r-graph") | |
70eb483a | 1580 | (version "1.64.0") |
5dfe4912 RW |
1581 | (source (origin |
1582 | (method url-fetch) | |
1583 | (uri (bioconductor-uri "graph" version)) | |
1584 | (sha256 | |
1585 | (base32 | |
70eb483a | 1586 | "1ivf59k7k552m7zd8g3wwazd71dq3xmgmhcq435738i02h0fqnyc")))) |
5dfe4912 RW |
1587 | (build-system r-build-system) |
1588 | (propagated-inputs | |
1589 | `(("r-biocgenerics" ,r-biocgenerics))) | |
1590 | (home-page "https://bioconductor.org/packages/graph") | |
1591 | (synopsis "Handle graph data structures in R") | |
1592 | (description | |
1593 | "This package implements some simple graph handling capabilities for R.") | |
1594 | (license license:artistic2.0))) | |
1595 | ||
8017eb0a RW |
1596 | ;; This is a CRAN package, but it depends on a Bioconductor package. |
1597 | (define-public r-ggm | |
1598 | (package | |
1599 | (name "r-ggm") | |
1600 | (version "2.5") | |
1601 | (source | |
1602 | (origin | |
1603 | (method url-fetch) | |
1604 | (uri (cran-uri "ggm" version)) | |
1605 | (sha256 | |
1606 | (base32 | |
1607 | "11wc6k2kj2ydy0dyks5mbvbhxm1r43id87anl1jg6dn0yv4m78di")))) | |
1608 | (properties `((upstream-name . "ggm"))) | |
1609 | (build-system r-build-system) | |
1610 | (propagated-inputs | |
1611 | `(("r-graph" ,r-graph) | |
1612 | ("r-igraph" ,r-igraph))) | |
1613 | (home-page "https://cran.r-project.org/package=ggm") | |
1614 | (synopsis "Functions for graphical Markov models") | |
1615 | (description | |
1616 | "This package provides functions and datasets for maximum likelihood | |
1617 | fitting of some classes of graphical Markov models.") | |
1618 | (license license:gpl2+))) | |
1619 | ||
a207bca2 RW |
1620 | (define-public r-codedepends |
1621 | (package | |
1622 | (name "r-codedepends") | |
1623 | (version "0.6.5") | |
1624 | (source | |
1625 | (origin | |
1626 | (method url-fetch) | |
1627 | (uri (cran-uri "CodeDepends" version)) | |
1628 | (sha256 | |
1629 | (base32 | |
1630 | "0l7kiv3awx50glf5cs841b4zzsff1ml90f0zr868ygvwsr4ps1hq")))) | |
1631 | (properties `((upstream-name . "CodeDepends"))) | |
1632 | (build-system r-build-system) | |
1633 | (propagated-inputs | |
1634 | `(("r-codetools" ,r-codetools) | |
1635 | ("r-graph" ,r-graph) | |
1636 | ("r-xml" ,r-xml))) | |
5e1f2362 | 1637 | (home-page "https://cran.r-project.org/web/packages/CodeDepends") |
a207bca2 RW |
1638 | (synopsis "Analysis of R code for reproducible research and code comprehension") |
1639 | (description | |
1640 | "This package provides tools for analyzing R expressions or blocks of | |
1641 | code and determining the dependencies between them. It focuses on R scripts, | |
1642 | but can be used on the bodies of functions. There are many facilities | |
1643 | including the ability to summarize or get a high-level view of code, | |
1644 | determining dependencies between variables, code improvement suggestions.") | |
1645 | ;; Any version of the GPL | |
1646 | (license (list license:gpl2+ license:gpl3+)))) | |
1647 | ||
793f83ef RJ |
1648 | (define-public r-chippeakanno |
1649 | (package | |
1650 | (name "r-chippeakanno") | |
8351faae | 1651 | (version "3.20.1") |
793f83ef RJ |
1652 | (source |
1653 | (origin | |
1654 | (method url-fetch) | |
1655 | (uri (bioconductor-uri "ChIPpeakAnno" version)) | |
1656 | (sha256 | |
1657 | (base32 | |
8351faae | 1658 | "0kmfha4vprbi0z6n7v9w28xfrqcx5qad7yfr0b316j5aj8v9f4hc")))) |
793f83ef RJ |
1659 | (properties `((upstream-name . "ChIPpeakAnno"))) |
1660 | (build-system r-build-system) | |
1661 | (propagated-inputs | |
85c1d20f RW |
1662 | `(("r-annotationdbi" ,r-annotationdbi) |
1663 | ("r-biobase" ,r-biobase) | |
1664 | ("r-biocgenerics" ,r-biocgenerics) | |
57d2fcd9 | 1665 | ("r-biocmanager" ,r-biocmanager) |
793f83ef | 1666 | ("r-biomart" ,r-biomart) |
85c1d20f | 1667 | ("r-biostrings" ,r-biostrings) |
793f83ef | 1668 | ("r-bsgenome" ,r-bsgenome) |
85c1d20f RW |
1669 | ("r-dbi" ,r-dbi) |
1670 | ("r-delayedarray" ,r-delayedarray) | |
1671 | ("r-ensembldb" ,r-ensembldb) | |
1672 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1673 | ("r-genomicalignments" ,r-genomicalignments) | |
793f83ef | 1674 | ("r-genomicfeatures" ,r-genomicfeatures) |
f794e85d | 1675 | ("r-genomicranges" ,r-genomicranges) |
85c1d20f RW |
1676 | ("r-go-db" ,r-go-db) |
1677 | ("r-graph" ,r-graph) | |
1678 | ("r-idr" ,r-idr) | |
f794e85d | 1679 | ("r-iranges" ,r-iranges) |
793f83ef | 1680 | ("r-limma" ,r-limma) |
85c1d20f | 1681 | ("r-matrixstats" ,r-matrixstats) |
793f83ef RJ |
1682 | ("r-multtest" ,r-multtest) |
1683 | ("r-rbgl" ,r-rbgl) | |
793f83ef | 1684 | ("r-regioner" ,r-regioner) |
85c1d20f RW |
1685 | ("r-rsamtools" ,r-rsamtools) |
1686 | ("r-rtracklayer" ,r-rtracklayer) | |
f794e85d | 1687 | ("r-s4vectors" ,r-s4vectors) |
793f83ef | 1688 | ("r-seqinr" ,r-seqinr) |
793f83ef | 1689 | ("r-summarizedexperiment" ,r-summarizedexperiment) |
793f83ef | 1690 | ("r-venndiagram" ,r-venndiagram))) |
99db6db7 | 1691 | (home-page "https://bioconductor.org/packages/ChIPpeakAnno") |
793f83ef RJ |
1692 | (synopsis "Peaks annotation from ChIP-seq and ChIP-chip experiments") |
1693 | (description | |
1694 | "The package includes functions to retrieve the sequences around the peak, | |
1695 | obtain enriched Gene Ontology (GO) terms, find the nearest gene, exon, miRNA or | |
1696 | custom features such as most conserved elements and other transcription factor | |
1697 | binding sites supplied by users. Starting 2.0.5, new functions have been added | |
1698 | for finding the peaks with bi-directional promoters with summary statistics | |
1699 | (peaksNearBDP), for summarizing the occurrence of motifs in peaks | |
1700 | (summarizePatternInPeaks) and for adding other IDs to annotated peaks or | |
1701 | enrichedGO (addGeneIDs).") | |
1702 | (license license:gpl2+))) | |
164502d8 RJ |
1703 | |
1704 | (define-public r-marray | |
1705 | (package | |
1706 | (name "r-marray") | |
b6c2f098 | 1707 | (version "1.64.0") |
164502d8 RJ |
1708 | (source (origin |
1709 | (method url-fetch) | |
1710 | (uri (bioconductor-uri "marray" version)) | |
1711 | (sha256 | |
b6c2f098 | 1712 | (base32 "1mbs9rk279hnm9yz34za3xz3hb88ll1d0abw4m2pgjgbh4kkhdrl")))) |
164502d8 RJ |
1713 | (build-system r-build-system) |
1714 | (propagated-inputs | |
67487088 | 1715 | `(("r-limma" ,r-limma))) |
99db6db7 | 1716 | (home-page "https://bioconductor.org/packages/marray") |
164502d8 RJ |
1717 | (synopsis "Exploratory analysis for two-color spotted microarray data") |
1718 | (description "This package contains class definitions for two-color spotted | |
ab8979fc | 1719 | microarray data. It also includes functions for data input, diagnostic plots, |
164502d8 RJ |
1720 | normalization and quality checking.") |
1721 | (license license:lgpl2.0+))) | |
0416a0d4 RJ |
1722 | |
1723 | (define-public r-cghbase | |
1724 | (package | |
1725 | (name "r-cghbase") | |
8341f706 | 1726 | (version "1.46.0") |
0416a0d4 RJ |
1727 | (source (origin |
1728 | (method url-fetch) | |
1729 | (uri (bioconductor-uri "CGHbase" version)) | |
1730 | (sha256 | |
8341f706 | 1731 | (base32 "0136pk6pfwpiiy9vca4pgg4wh74jfb5ssglpdszzhamljpvg765x")))) |
0416a0d4 RJ |
1732 | (properties `((upstream-name . "CGHbase"))) |
1733 | (build-system r-build-system) | |
1734 | (propagated-inputs | |
1735 | `(("r-biobase" ,r-biobase) | |
1736 | ("r-marray" ,r-marray))) | |
99db6db7 | 1737 | (home-page "https://bioconductor.org/packages/CGHbase") |
0416a0d4 RJ |
1738 | (synopsis "Base functions and classes for arrayCGH data analysis") |
1739 | (description "This package contains functions and classes that are needed by | |
1740 | the @code{arrayCGH} packages.") | |
1741 | (license license:gpl2+))) | |
67ee83d6 RJ |
1742 | |
1743 | (define-public r-cghcall | |
1744 | (package | |
1745 | (name "r-cghcall") | |
8f2a4ea1 | 1746 | (version "2.48.0") |
67ee83d6 RJ |
1747 | (source (origin |
1748 | (method url-fetch) | |
1749 | (uri (bioconductor-uri "CGHcall" version)) | |
1750 | (sha256 | |
8f2a4ea1 | 1751 | (base32 "1x8pz7zhw2nabik1vgdhlivndqvil3s7vnl5070k493v6gza0p3s")))) |
67ee83d6 RJ |
1752 | (properties `((upstream-name . "CGHcall"))) |
1753 | (build-system r-build-system) | |
1754 | (propagated-inputs | |
1755 | `(("r-biobase" ,r-biobase) | |
1756 | ("r-cghbase" ,r-cghbase) | |
1757 | ("r-impute" ,r-impute) | |
1758 | ("r-dnacopy" ,r-dnacopy) | |
1759 | ("r-snowfall" ,r-snowfall))) | |
99db6db7 | 1760 | (home-page "https://bioconductor.org/packages/CGHcall") |
67ee83d6 RJ |
1761 | (synopsis "Base functions and classes for arrayCGH data analysis") |
1762 | (description "This package contains functions and classes that are needed by | |
1763 | @code{arrayCGH} packages.") | |
1764 | (license license:gpl2+))) | |
0ef8cc9c RJ |
1765 | |
1766 | (define-public r-qdnaseq | |
1767 | (package | |
1768 | (name "r-qdnaseq") | |
23ce5ad1 | 1769 | (version "1.22.0") |
0ef8cc9c RJ |
1770 | (source (origin |
1771 | (method url-fetch) | |
1772 | (uri (bioconductor-uri "QDNAseq" version)) | |
1773 | (sha256 | |
23ce5ad1 | 1774 | (base32 "0xcqdpv9a47zpxx0q9sif5y4s1yzx3pig0kywy961kh5xgl5bcrq")))) |
0ef8cc9c RJ |
1775 | (properties `((upstream-name . "QDNAseq"))) |
1776 | (build-system r-build-system) | |
1777 | (propagated-inputs | |
1778 | `(("r-biobase" ,r-biobase) | |
1779 | ("r-cghbase" ,r-cghbase) | |
1780 | ("r-cghcall" ,r-cghcall) | |
1781 | ("r-dnacopy" ,r-dnacopy) | |
23ce5ad1 RW |
1782 | ("r-future" ,r-future) |
1783 | ("r-future-apply" ,r-future-apply) | |
0ef8cc9c RJ |
1784 | ("r-genomicranges" ,r-genomicranges) |
1785 | ("r-iranges" ,r-iranges) | |
1786 | ("r-matrixstats" ,r-matrixstats) | |
1787 | ("r-r-utils" ,r-r-utils) | |
1788 | ("r-rsamtools" ,r-rsamtools))) | |
99db6db7 | 1789 | (home-page "https://bioconductor.org/packages/QDNAseq") |
0ef8cc9c RJ |
1790 | (synopsis "Quantitative DNA sequencing for chromosomal aberrations") |
1791 | (description "The genome is divided into non-overlapping fixed-sized bins, | |
1792 | number of sequence reads in each counted, adjusted with a simultaneous | |
1793 | two-dimensional loess correction for sequence mappability and GC content, and | |
1794 | filtered to remove spurious regions in the genome. Downstream steps of | |
1795 | segmentation and calling are also implemented via packages DNAcopy and CGHcall, | |
1796 | respectively.") | |
1797 | (license license:gpl2+))) | |
bb15b581 RW |
1798 | |
1799 | (define-public r-bayseq | |
1800 | (package | |
1801 | (name "r-bayseq") | |
d7722823 | 1802 | (version "2.20.0") |
bb15b581 RW |
1803 | (source |
1804 | (origin | |
1805 | (method url-fetch) | |
1806 | (uri (bioconductor-uri "baySeq" version)) | |
1807 | (sha256 | |
1808 | (base32 | |
d7722823 | 1809 | "040s1d3756spyzblkyx2vcy7bn3vf87mhsp3is35yxkj55n3myjk")))) |
bb15b581 RW |
1810 | (properties `((upstream-name . "baySeq"))) |
1811 | (build-system r-build-system) | |
1812 | (propagated-inputs | |
1813 | `(("r-abind" ,r-abind) | |
1814 | ("r-edger" ,r-edger) | |
1815 | ("r-genomicranges" ,r-genomicranges))) | |
1816 | (home-page "https://bioconductor.org/packages/baySeq/") | |
1817 | (synopsis "Bayesian analysis of differential expression patterns in count data") | |
1818 | (description | |
1819 | "This package identifies differential expression in high-throughput count | |
1820 | data, such as that derived from next-generation sequencing machines, | |
1821 | calculating estimated posterior likelihoods of differential expression (or | |
1822 | more complex hypotheses) via empirical Bayesian methods.") | |
1823 | (license license:gpl3))) | |
609f4ad1 RW |
1824 | |
1825 | (define-public r-chipcomp | |
1826 | (package | |
1827 | (name "r-chipcomp") | |
b0897fbf | 1828 | (version "1.16.0") |
609f4ad1 RW |
1829 | (source |
1830 | (origin | |
1831 | (method url-fetch) | |
1832 | (uri (bioconductor-uri "ChIPComp" version)) | |
1833 | (sha256 | |
1834 | (base32 | |
b0897fbf | 1835 | "0wk0vvg6dk9wk60lzbadrnqar75dppvyr4hiwrhv9rhhah2mg2mg")))) |
609f4ad1 RW |
1836 | (properties `((upstream-name . "ChIPComp"))) |
1837 | (build-system r-build-system) | |
1838 | (propagated-inputs | |
1839 | `(("r-biocgenerics" ,r-biocgenerics) | |
1840 | ("r-bsgenome-hsapiens-ucsc-hg19" ,r-bsgenome-hsapiens-ucsc-hg19) | |
1841 | ("r-bsgenome-mmusculus-ucsc-mm9" ,r-bsgenome-mmusculus-ucsc-mm9) | |
1842 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1843 | ("r-genomicranges" ,r-genomicranges) | |
1844 | ("r-iranges" ,r-iranges) | |
1845 | ("r-limma" ,r-limma) | |
1846 | ("r-rsamtools" ,r-rsamtools) | |
1847 | ("r-rtracklayer" ,r-rtracklayer) | |
1848 | ("r-s4vectors" ,r-s4vectors))) | |
1849 | (home-page "https://bioconductor.org/packages/ChIPComp") | |
1850 | (synopsis "Quantitative comparison of multiple ChIP-seq datasets") | |
1851 | (description | |
1852 | "ChIPComp implements a statistical method for quantitative comparison of | |
1853 | multiple ChIP-seq datasets. It detects differentially bound sharp binding | |
1854 | sites across multiple conditions considering matching control in ChIP-seq | |
1855 | datasets.") | |
1856 | ;; Any version of the GPL. | |
1857 | (license license:gpl3+))) | |
0490f9de RW |
1858 | |
1859 | (define-public r-riboprofiling | |
1860 | (package | |
1861 | (name "r-riboprofiling") | |
88af7049 | 1862 | (version "1.16.0") |
0490f9de RW |
1863 | (source |
1864 | (origin | |
1865 | (method url-fetch) | |
1866 | (uri (bioconductor-uri "RiboProfiling" version)) | |
1867 | (sha256 | |
1868 | (base32 | |
88af7049 | 1869 | "0nfzyiq7cd6fs5agzl1zyfg8s631wi7kjngiyvd3vxlhi8wsjicx")))) |
0490f9de RW |
1870 | (properties `((upstream-name . "RiboProfiling"))) |
1871 | (build-system r-build-system) | |
1872 | (propagated-inputs | |
1873 | `(("r-biocgenerics" ,r-biocgenerics) | |
1874 | ("r-biostrings" ,r-biostrings) | |
1875 | ("r-data-table" ,r-data-table) | |
1876 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1877 | ("r-genomicalignments" ,r-genomicalignments) | |
1878 | ("r-genomicfeatures" ,r-genomicfeatures) | |
1879 | ("r-genomicranges" ,r-genomicranges) | |
1880 | ("r-ggbio" ,r-ggbio) | |
1881 | ("r-ggplot2" ,r-ggplot2) | |
1882 | ("r-iranges" ,r-iranges) | |
1883 | ("r-plyr" ,r-plyr) | |
1884 | ("r-reshape2" ,r-reshape2) | |
1885 | ("r-rsamtools" ,r-rsamtools) | |
1886 | ("r-rtracklayer" ,r-rtracklayer) | |
1887 | ("r-s4vectors" ,r-s4vectors) | |
1888 | ("r-sqldf" ,r-sqldf))) | |
1889 | (home-page "https://bioconductor.org/packages/RiboProfiling/") | |
1890 | (synopsis "Ribosome profiling data analysis") | |
1891 | (description "Starting with a BAM file, this package provides the | |
1892 | necessary functions for quality assessment, read start position recalibration, | |
1893 | the counting of genomic sequence reads on CDS, 3'UTR, and 5'UTR, and plotting | |
1894 | of count data: pairs, log fold-change, codon frequency and coverage | |
1895 | assessment, principal component analysis on codon coverage.") | |
1896 | (license license:gpl3))) | |
6ffdfe6a RW |
1897 | |
1898 | (define-public r-riboseqr | |
1899 | (package | |
1900 | (name "r-riboseqr") | |
595b6c9a | 1901 | (version "1.20.0") |
6ffdfe6a RW |
1902 | (source |
1903 | (origin | |
1904 | (method url-fetch) | |
1905 | (uri (bioconductor-uri "riboSeqR" version)) | |
1906 | (sha256 | |
1907 | (base32 | |
595b6c9a | 1908 | "1jr7h64hyhyf9gf15lah6iqwyljfc8mraf9kya4lql6lcjjkjiqm")))) |
6ffdfe6a RW |
1909 | (properties `((upstream-name . "riboSeqR"))) |
1910 | (build-system r-build-system) | |
1911 | (propagated-inputs | |
1912 | `(("r-abind" ,r-abind) | |
1913 | ("r-bayseq" ,r-bayseq) | |
1914 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1915 | ("r-genomicranges" ,r-genomicranges) | |
1916 | ("r-iranges" ,r-iranges) | |
1917 | ("r-rsamtools" ,r-rsamtools) | |
1918 | ("r-seqlogo" ,r-seqlogo))) | |
1919 | (home-page "https://bioconductor.org/packages/riboSeqR/") | |
1920 | (synopsis "Analysis of sequencing data from ribosome profiling experiments") | |
1921 | (description | |
1922 | "This package provides plotting functions, frameshift detection and | |
1923 | parsing of genetic sequencing data from ribosome profiling experiments.") | |
1924 | (license license:gpl3))) | |
a32279ff RW |
1925 | |
1926 | (define-public r-interactionset | |
1927 | (package | |
1928 | (name "r-interactionset") | |
bb841742 | 1929 | (version "1.14.0") |
a32279ff RW |
1930 | (source |
1931 | (origin | |
1932 | (method url-fetch) | |
1933 | (uri (bioconductor-uri "InteractionSet" version)) | |
1934 | (sha256 | |
1935 | (base32 | |
bb841742 | 1936 | "0n2l95h56x5g68p10cap8p4x3a6vaph2hjlk09vmi3j48lrzb2kh")))) |
a32279ff RW |
1937 | (properties |
1938 | `((upstream-name . "InteractionSet"))) | |
1939 | (build-system r-build-system) | |
1940 | (propagated-inputs | |
1941 | `(("r-biocgenerics" ,r-biocgenerics) | |
1942 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1943 | ("r-genomicranges" ,r-genomicranges) | |
1944 | ("r-iranges" ,r-iranges) | |
1945 | ("r-matrix" ,r-matrix) | |
1946 | ("r-rcpp" ,r-rcpp) | |
1947 | ("r-s4vectors" ,r-s4vectors) | |
1948 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
1949 | (home-page "https://bioconductor.org/packages/InteractionSet") | |
1950 | (synopsis "Base classes for storing genomic interaction data") | |
1951 | (description | |
02fe0976 | 1952 | "This package provides the @code{GInteractions}, |
a32279ff RW |
1953 | @code{InteractionSet} and @code{ContactMatrix} objects and associated methods |
1954 | for storing and manipulating genomic interaction data from Hi-C and ChIA-PET | |
1955 | experiments.") | |
1956 | (license license:gpl3))) | |
cf9a29b2 RW |
1957 | |
1958 | (define-public r-genomicinteractions | |
1959 | (package | |
1960 | (name "r-genomicinteractions") | |
5bf71022 | 1961 | (version "1.20.1") |
cf9a29b2 RW |
1962 | (source |
1963 | (origin | |
1964 | (method url-fetch) | |
1965 | (uri (bioconductor-uri "GenomicInteractions" version)) | |
1966 | (sha256 | |
1967 | (base32 | |
5bf71022 | 1968 | "140bp7c8p079xh5wwxmrq3a73pm6mdc9czq5w2gzjml7dgrca38a")))) |
cf9a29b2 RW |
1969 | (properties |
1970 | `((upstream-name . "GenomicInteractions"))) | |
1971 | (build-system r-build-system) | |
1972 | (propagated-inputs | |
1973 | `(("r-biobase" ,r-biobase) | |
1974 | ("r-biocgenerics" ,r-biocgenerics) | |
1975 | ("r-data-table" ,r-data-table) | |
1976 | ("r-dplyr" ,r-dplyr) | |
1977 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1978 | ("r-genomicranges" ,r-genomicranges) | |
1979 | ("r-ggplot2" ,r-ggplot2) | |
1980 | ("r-gridextra" ,r-gridextra) | |
1981 | ("r-gviz" ,r-gviz) | |
1982 | ("r-igraph" ,r-igraph) | |
1983 | ("r-interactionset" ,r-interactionset) | |
1984 | ("r-iranges" ,r-iranges) | |
1985 | ("r-rsamtools" ,r-rsamtools) | |
1986 | ("r-rtracklayer" ,r-rtracklayer) | |
1987 | ("r-s4vectors" ,r-s4vectors) | |
1988 | ("r-stringr" ,r-stringr))) | |
1989 | (home-page "https://github.com/ComputationalRegulatoryGenomicsICL/GenomicInteractions/") | |
1990 | (synopsis "R package for handling genomic interaction data") | |
1991 | (description | |
1992 | "This R package provides tools for handling genomic interaction data, | |
1993 | such as ChIA-PET/Hi-C, annotating genomic features with interaction | |
1994 | information and producing various plots and statistics.") | |
1995 | (license license:gpl3))) | |
27c51606 RW |
1996 | |
1997 | (define-public r-ctc | |
1998 | (package | |
1999 | (name "r-ctc") | |
b2b5b031 | 2000 | (version "1.60.0") |
27c51606 RW |
2001 | (source |
2002 | (origin | |
2003 | (method url-fetch) | |
2004 | (uri (bioconductor-uri "ctc" version)) | |
2005 | (sha256 | |
2006 | (base32 | |
b2b5b031 | 2007 | "0wh27izkyr1j26nznisw654mb5c94xpwjjkx7r6bhwg9ihxxcl6d")))) |
27c51606 RW |
2008 | (build-system r-build-system) |
2009 | (propagated-inputs `(("r-amap" ,r-amap))) | |
2010 | (home-page "https://bioconductor.org/packages/ctc/") | |
2011 | (synopsis "Cluster and tree conversion") | |
2012 | (description | |
2013 | "This package provides tools for exporting and importing classification | |
2014 | trees and clusters to other programs.") | |
2015 | (license license:gpl2))) | |
5da0e142 RW |
2016 | |
2017 | (define-public r-goseq | |
2018 | (package | |
2019 | (name "r-goseq") | |
ab7f3cbb | 2020 | (version "1.38.0") |
5da0e142 RW |
2021 | (source |
2022 | (origin | |
2023 | (method url-fetch) | |
2024 | (uri (bioconductor-uri "goseq" version)) | |
2025 | (sha256 | |
2026 | (base32 | |
ab7f3cbb | 2027 | "11ypa41qv1nx3cncxlwlbhdxqlwq95rb9byv2z3crrf9nfp24byv")))) |
5da0e142 RW |
2028 | (build-system r-build-system) |
2029 | (propagated-inputs | |
2030 | `(("r-annotationdbi" ,r-annotationdbi) | |
2031 | ("r-biasedurn" ,r-biasedurn) | |
2032 | ("r-biocgenerics" ,r-biocgenerics) | |
2033 | ("r-genelendatabase" ,r-genelendatabase) | |
2034 | ("r-go-db" ,r-go-db) | |
2035 | ("r-mgcv" ,r-mgcv))) | |
2036 | (home-page "https://bioconductor.org/packages/goseq/") | |
2037 | (synopsis "Gene Ontology analyser for RNA-seq and other length biased data") | |
2038 | (description | |
2039 | "This package provides tools to detect Gene Ontology and/or other user | |
2040 | defined categories which are over/under represented in RNA-seq data.") | |
2041 | (license license:lgpl2.0+))) | |
f4235c0e RW |
2042 | |
2043 | (define-public r-glimma | |
2044 | (package | |
2045 | (name "r-glimma") | |
728571fb | 2046 | (version "1.14.0") |
f4235c0e RW |
2047 | (source |
2048 | (origin | |
2049 | (method url-fetch) | |
2050 | (uri (bioconductor-uri "Glimma" version)) | |
2051 | (sha256 | |
2052 | (base32 | |
728571fb | 2053 | "1rjrqgl96iz4b3xqpc174wgz7bqmc8gbm9ljag0y27kz29fwng8r")))) |
f4235c0e RW |
2054 | (properties `((upstream-name . "Glimma"))) |
2055 | (build-system r-build-system) | |
2056 | (propagated-inputs | |
2057 | `(("r-edger" ,r-edger) | |
2058 | ("r-jsonlite" ,r-jsonlite) | |
2059 | ("r-s4vectors" ,r-s4vectors))) | |
2060 | (home-page "https://github.com/Shians/Glimma") | |
2061 | (synopsis "Interactive HTML graphics") | |
2062 | (description | |
2063 | "This package generates interactive visualisations for analysis of | |
2064 | RNA-sequencing data using output from limma, edgeR or DESeq2 packages in an | |
2065 | HTML page. The interactions are built on top of the popular static | |
2066 | representations of analysis results in order to provide additional | |
2067 | information.") | |
2068 | (license license:lgpl3))) | |
aa388dc7 RW |
2069 | |
2070 | (define-public r-rots | |
2071 | (package | |
2072 | (name "r-rots") | |
9c071144 | 2073 | (version "1.14.0") |
aa388dc7 RW |
2074 | (source |
2075 | (origin | |
2076 | (method url-fetch) | |
2077 | (uri (bioconductor-uri "ROTS" version)) | |
2078 | (sha256 | |
2079 | (base32 | |
9c071144 | 2080 | "08mwlb0lpprys2b7vif8aj5bnprmn09mm79zz158gbhrv9j9d1qm")))) |
aa388dc7 RW |
2081 | (properties `((upstream-name . "ROTS"))) |
2082 | (build-system r-build-system) | |
2083 | (propagated-inputs | |
2084 | `(("r-biobase" ,r-biobase) | |
2085 | ("r-rcpp" ,r-rcpp))) | |
2086 | (home-page "https://bioconductor.org/packages/ROTS/") | |
2087 | (synopsis "Reproducibility-Optimized Test Statistic") | |
2088 | (description | |
2089 | "This package provides tools for calculating the | |
2090 | @dfn{Reproducibility-Optimized Test Statistic} (ROTS) for differential testing | |
2091 | in omics data.") | |
2092 | (license license:gpl2+))) | |
b64ce4b7 | 2093 | |
cad6fb2d RW |
2094 | (define-public r-plgem |
2095 | (package | |
2096 | (name "r-plgem") | |
565bb84b | 2097 | (version "1.58.0") |
cad6fb2d RW |
2098 | (source |
2099 | (origin | |
2100 | (method url-fetch) | |
2101 | (uri (bioconductor-uri "plgem" version)) | |
2102 | (sha256 | |
2103 | (base32 | |
565bb84b | 2104 | "0fkyvcw2qxp4g527s9rzia45yapi0r6gbij7svisil8rbgfdp45v")))) |
cad6fb2d RW |
2105 | (build-system r-build-system) |
2106 | (propagated-inputs | |
2107 | `(("r-biobase" ,r-biobase) | |
2108 | ("r-mass" ,r-mass))) | |
2109 | (home-page "http://www.genopolis.it") | |
2110 | (synopsis "Detect differential expression in microarray and proteomics datasets") | |
2111 | (description | |
2112 | "The Power Law Global Error Model (PLGEM) has been shown to faithfully | |
2113 | model the variance-versus-mean dependence that exists in a variety of | |
2114 | genome-wide datasets, including microarray and proteomics data. The use of | |
2115 | PLGEM has been shown to improve the detection of differentially expressed | |
2116 | genes or proteins in these datasets.") | |
2117 | (license license:gpl2))) | |
2118 | ||
b64ce4b7 RW |
2119 | (define-public r-inspect |
2120 | (package | |
2121 | (name "r-inspect") | |
b7e86efd | 2122 | (version "1.16.3") |
b64ce4b7 RW |
2123 | (source |
2124 | (origin | |
2125 | (method url-fetch) | |
2126 | (uri (bioconductor-uri "INSPEcT" version)) | |
2127 | (sha256 | |
2128 | (base32 | |
b7e86efd | 2129 | "0y4gpvrbmcipdnyz9lz9ywn0317xnpcriiisqvxygin05vgcpilp")))) |
b64ce4b7 RW |
2130 | (properties `((upstream-name . "INSPEcT"))) |
2131 | (build-system r-build-system) | |
2132 | (propagated-inputs | |
2133 | `(("r-biobase" ,r-biobase) | |
2134 | ("r-biocgenerics" ,r-biocgenerics) | |
2135 | ("r-biocparallel" ,r-biocparallel) | |
c86fc969 | 2136 | ("r-deseq2" ,r-deseq2) |
b64ce4b7 | 2137 | ("r-desolve" ,r-desolve) |
bd824de3 | 2138 | ("r-gdata" ,r-gdata) |
74bb4cdf | 2139 | ("r-genomeinfodb" ,r-genomeinfodb) |
b64ce4b7 RW |
2140 | ("r-genomicalignments" ,r-genomicalignments) |
2141 | ("r-genomicfeatures" ,r-genomicfeatures) | |
2142 | ("r-genomicranges" ,r-genomicranges) | |
2143 | ("r-iranges" ,r-iranges) | |
74bb4cdf | 2144 | ("r-kernsmooth" ,r-kernsmooth) |
c86fc969 | 2145 | ("r-plgem" ,r-plgem) |
b64ce4b7 RW |
2146 | ("r-proc" ,r-proc) |
2147 | ("r-rootsolve" ,r-rootsolve) | |
2148 | ("r-rsamtools" ,r-rsamtools) | |
c86fc969 RW |
2149 | ("r-s4vectors" ,r-s4vectors) |
2150 | ("r-shiny" ,r-shiny) | |
2151 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
2152 | ("r-txdb-mmusculus-ucsc-mm9-knowngene" | |
2153 | ,r-txdb-mmusculus-ucsc-mm9-knowngene))) | |
b64ce4b7 RW |
2154 | (home-page "https://bioconductor.org/packages/INSPEcT") |
2155 | (synopsis "Analysis of 4sU-seq and RNA-seq time-course data") | |
2156 | (description | |
2157 | "INSPEcT (INference of Synthesis, Processing and dEgradation rates in | |
2158 | Time-Course experiments) analyses 4sU-seq and RNA-seq time-course data in | |
2159 | order to evaluate synthesis, processing and degradation rates and assess via | |
2160 | modeling the rates that determines changes in mature mRNA levels.") | |
2161 | (license license:gpl2))) | |
f6e99763 RW |
2162 | |
2163 | (define-public r-dnabarcodes | |
2164 | (package | |
2165 | (name "r-dnabarcodes") | |
2d86dc20 | 2166 | (version "1.16.0") |
f6e99763 RW |
2167 | (source |
2168 | (origin | |
2169 | (method url-fetch) | |
2170 | (uri (bioconductor-uri "DNABarcodes" version)) | |
2171 | (sha256 | |
2172 | (base32 | |
2d86dc20 | 2173 | "0r2r9qc2qvf7rfl1h5ynvv3xd7n444zbc697s85qxqdpr4sxqmfd")))) |
f6e99763 RW |
2174 | (properties `((upstream-name . "DNABarcodes"))) |
2175 | (build-system r-build-system) | |
2176 | (propagated-inputs | |
2177 | `(("r-bh" ,r-bh) | |
2178 | ("r-matrix" ,r-matrix) | |
2179 | ("r-rcpp" ,r-rcpp))) | |
2180 | (home-page "https://bioconductor.org/packages/DNABarcodes") | |
2181 | (synopsis "Create and analyze DNA barcodes") | |
2182 | (description | |
2183 | "This package offers tools to create DNA barcode sets capable of | |
2184 | correcting insertion, deletion, and substitution errors. Existing barcodes | |
2185 | can be analyzed regarding their minimal, maximal and average distances between | |
2186 | barcodes. Finally, reads that start with a (possibly mutated) barcode can be | |
2187 | demultiplexed, i.e. assigned to their original reference barcode.") | |
2188 | (license license:gpl2))) | |
09aa3d06 RW |
2189 | |
2190 | (define-public r-ruvseq | |
2191 | (package | |
2192 | (name "r-ruvseq") | |
efd09347 | 2193 | (version "1.20.0") |
09aa3d06 RW |
2194 | (source |
2195 | (origin | |
2196 | (method url-fetch) | |
2197 | (uri (bioconductor-uri "RUVSeq" version)) | |
2198 | (sha256 | |
2199 | (base32 | |
efd09347 | 2200 | "1ipbbzpngx988lsmwqv7vbmqm65m43xvsmipayfppkrr6jipzxrj")))) |
09aa3d06 RW |
2201 | (properties `((upstream-name . "RUVSeq"))) |
2202 | (build-system r-build-system) | |
2203 | (propagated-inputs | |
2204 | `(("r-biobase" ,r-biobase) | |
2205 | ("r-edaseq" ,r-edaseq) | |
2206 | ("r-edger" ,r-edger) | |
2207 | ("r-mass" ,r-mass))) | |
2208 | (home-page "https://github.com/drisso/RUVSeq") | |
2209 | (synopsis "Remove unwanted variation from RNA-Seq data") | |
2210 | (description | |
2211 | "This package implements methods to @dfn{remove unwanted variation} (RUV) | |
2212 | of Risso et al. (2014) for the normalization of RNA-Seq read counts between | |
2213 | samples.") | |
2214 | (license license:artistic2.0))) | |
286157dc RW |
2215 | |
2216 | (define-public r-biocneighbors | |
2217 | (package | |
2218 | (name "r-biocneighbors") | |
aece78fe | 2219 | (version "1.4.2") |
286157dc RW |
2220 | (source |
2221 | (origin | |
2222 | (method url-fetch) | |
2223 | (uri (bioconductor-uri "BiocNeighbors" version)) | |
2224 | (sha256 | |
2225 | (base32 | |
aece78fe | 2226 | "1bx7i5pifj8w89fnhfgcfgcar2ik2ad8wqs2rix7yks90vz185i6")))) |
286157dc RW |
2227 | (properties `((upstream-name . "BiocNeighbors"))) |
2228 | (build-system r-build-system) | |
2229 | (propagated-inputs | |
12e2aa96 RW |
2230 | `(("r-biocparallel" ,r-biocparallel) |
2231 | ("r-matrix" ,r-matrix) | |
286157dc RW |
2232 | ("r-rcpp" ,r-rcpp) |
2233 | ("r-rcppannoy" ,r-rcppannoy) | |
6fc161fc | 2234 | ("r-rcpphnsw" ,r-rcpphnsw) |
286157dc RW |
2235 | ("r-s4vectors" ,r-s4vectors))) |
2236 | (home-page "https://bioconductor.org/packages/BiocNeighbors") | |
2237 | (synopsis "Nearest Neighbor Detection for Bioconductor packages") | |
2238 | (description | |
2239 | "This package implements exact and approximate methods for nearest | |
2240 | neighbor detection, in a framework that allows them to be easily switched | |
2241 | within Bioconductor packages or workflows. The exact algorithm is implemented | |
2242 | using pre-clustering with the k-means algorithm. Functions are also provided | |
2243 | to search for all neighbors within a given distance. Parallelization is | |
2244 | achieved for all methods using the BiocParallel framework.") | |
2245 | (license license:gpl3))) | |
8a587c89 | 2246 | |
99391290 RW |
2247 | (define-public r-biocsingular |
2248 | (package | |
2249 | (name "r-biocsingular") | |
effbf7d9 | 2250 | (version "1.2.2") |
99391290 RW |
2251 | (source |
2252 | (origin | |
2253 | (method url-fetch) | |
2254 | (uri (bioconductor-uri "BiocSingular" version)) | |
2255 | (sha256 | |
2256 | (base32 | |
effbf7d9 | 2257 | "1282fdwxrpga87y8xflr0sl8ajwawgn2i9i65my8mbg5vrixs407")))) |
99391290 RW |
2258 | (properties `((upstream-name . "BiocSingular"))) |
2259 | (build-system r-build-system) | |
2260 | (propagated-inputs | |
2261 | `(("r-beachmat" ,r-beachmat) | |
2262 | ("r-biocgenerics" ,r-biocgenerics) | |
2263 | ("r-biocparallel" ,r-biocparallel) | |
2264 | ("r-delayedarray" ,r-delayedarray) | |
2265 | ("r-irlba" ,r-irlba) | |
2266 | ("r-matrix" ,r-matrix) | |
2267 | ("r-rcpp" ,r-rcpp) | |
2268 | ("r-rsvd" ,r-rsvd) | |
2269 | ("r-s4vectors" ,r-s4vectors))) | |
2270 | (home-page "https://github.com/LTLA/BiocSingular") | |
2271 | (synopsis "Singular value decomposition for Bioconductor packages") | |
2272 | (description | |
2273 | "This package implements exact and approximate methods for singular value | |
2274 | decomposition and principal components analysis, in a framework that allows | |
2275 | them to be easily switched within Bioconductor packages or workflows. Where | |
2276 | possible, parallelization is achieved using the BiocParallel framework.") | |
2277 | (license license:gpl3))) | |
2278 | ||
a961ae46 RW |
2279 | (define-public r-destiny |
2280 | (package | |
2281 | (name "r-destiny") | |
062cbc4f | 2282 | (version "3.0.1") |
a961ae46 RW |
2283 | (source |
2284 | (origin | |
2285 | (method url-fetch) | |
2286 | (uri (bioconductor-uri "destiny" version)) | |
2287 | (sha256 | |
2288 | (base32 | |
062cbc4f | 2289 | "1hzg53p1cz21bvnfyyz40bpvjhg89zi3rahlqf0c4w85iwc1i4vi")))) |
a961ae46 RW |
2290 | (build-system r-build-system) |
2291 | (propagated-inputs | |
2292 | `(("r-biobase" ,r-biobase) | |
2293 | ("r-biocgenerics" ,r-biocgenerics) | |
6e10ac07 | 2294 | ("r-ggplot-multistats" ,r-ggplot-multistats) |
0aa72f2d | 2295 | ("r-ggplot2" ,r-ggplot2) |
a961ae46 | 2296 | ("r-ggthemes" ,r-ggthemes) |
6e10ac07 RW |
2297 | ("r-irlba" ,r-irlba) |
2298 | ("r-knn-covertree" ,r-knn-covertree) | |
a961ae46 | 2299 | ("r-matrix" ,r-matrix) |
6e10ac07 | 2300 | ("r-pcamethods" ,r-pcamethods) |
a961ae46 RW |
2301 | ("r-proxy" ,r-proxy) |
2302 | ("r-rcpp" ,r-rcpp) | |
2303 | ("r-rcppeigen" ,r-rcppeigen) | |
6e10ac07 RW |
2304 | ("r-rcpphnsw" ,r-rcpphnsw) |
2305 | ("r-rspectra" ,r-rspectra) | |
a961ae46 RW |
2306 | ("r-scales" ,r-scales) |
2307 | ("r-scatterplot3d" ,r-scatterplot3d) | |
6e10ac07 | 2308 | ("r-singlecellexperiment" ,r-singlecellexperiment) |
a961ae46 RW |
2309 | ("r-smoother" ,r-smoother) |
2310 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
6e10ac07 RW |
2311 | ("r-tidyr" ,r-tidyr) |
2312 | ("r-tidyselect" ,r-tidyselect) | |
a961ae46 RW |
2313 | ("r-vim" ,r-vim))) |
2314 | (home-page "https://bioconductor.org/packages/destiny/") | |
2315 | (synopsis "Create and plot diffusion maps") | |
2316 | (description "This package provides tools to create and plot diffusion | |
2317 | maps.") | |
2318 | ;; Any version of the GPL | |
2319 | (license license:gpl3+))) | |
2320 | ||
8a587c89 RW |
2321 | (define-public r-savr |
2322 | (package | |
2323 | (name "r-savr") | |
2e17cbd7 | 2324 | (version "1.24.0") |
8a587c89 RW |
2325 | (source |
2326 | (origin | |
2327 | (method url-fetch) | |
2328 | (uri (bioconductor-uri "savR" version)) | |
2329 | (sha256 | |
2330 | (base32 | |
2e17cbd7 | 2331 | "1lsnqjl6qxbj0wai05qb2wrxrhxq5iarv2livmvwiwv70iigqygf")))) |
8a587c89 RW |
2332 | (properties `((upstream-name . "savR"))) |
2333 | (build-system r-build-system) | |
2334 | (propagated-inputs | |
2335 | `(("r-ggplot2" ,r-ggplot2) | |
2336 | ("r-gridextra" ,r-gridextra) | |
2337 | ("r-reshape2" ,r-reshape2) | |
2338 | ("r-scales" ,r-scales) | |
2339 | ("r-xml" ,r-xml))) | |
2340 | (home-page "https://github.com/bcalder/savR") | |
2341 | (synopsis "Parse and analyze Illumina SAV files") | |
2342 | (description | |
2343 | "This package provides tools to parse Illumina Sequence Analysis | |
2344 | Viewer (SAV) files, access data, and generate QC plots.") | |
2345 | (license license:agpl3+))) | |
41ffc214 RW |
2346 | |
2347 | (define-public r-chipexoqual | |
2348 | (package | |
2349 | (name "r-chipexoqual") | |
84825e55 | 2350 | (version "1.10.0") |
41ffc214 RW |
2351 | (source |
2352 | (origin | |
2353 | (method url-fetch) | |
2354 | (uri (bioconductor-uri "ChIPexoQual" version)) | |
2355 | (sha256 | |
2356 | (base32 | |
84825e55 | 2357 | "044n6kn16qczpdhp0w0z5x8xpr0rfs9s8q70rafgnvj7a2q1xdd0")))) |
41ffc214 RW |
2358 | (properties `((upstream-name . "ChIPexoQual"))) |
2359 | (build-system r-build-system) | |
2360 | (propagated-inputs | |
2361 | `(("r-biocparallel" ,r-biocparallel) | |
2362 | ("r-biovizbase" ,r-biovizbase) | |
2363 | ("r-broom" ,r-broom) | |
2364 | ("r-data-table" ,r-data-table) | |
2365 | ("r-dplyr" ,r-dplyr) | |
2366 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2367 | ("r-genomicalignments" ,r-genomicalignments) | |
2368 | ("r-genomicranges" ,r-genomicranges) | |
2369 | ("r-ggplot2" ,r-ggplot2) | |
2370 | ("r-hexbin" ,r-hexbin) | |
2371 | ("r-iranges" ,r-iranges) | |
2372 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
2373 | ("r-rmarkdown" ,r-rmarkdown) | |
2374 | ("r-rsamtools" ,r-rsamtools) | |
2375 | ("r-s4vectors" ,r-s4vectors) | |
2376 | ("r-scales" ,r-scales) | |
2377 | ("r-viridis" ,r-viridis))) | |
2378 | (home-page "https://github.com/keleslab/ChIPexoQual") | |
2379 | (synopsis "Quality control pipeline for ChIP-exo/nexus data") | |
2380 | (description | |
2381 | "This package provides a quality control pipeline for ChIP-exo/nexus | |
2382 | sequencing data.") | |
2383 | (license license:gpl2+))) | |
c18dccff | 2384 | |
3d13b448 RW |
2385 | (define-public r-copynumber |
2386 | (package | |
2387 | (name "r-copynumber") | |
eb3fd382 | 2388 | (version "1.26.0") |
3d13b448 RW |
2389 | (source (origin |
2390 | (method url-fetch) | |
2391 | (uri (bioconductor-uri "copynumber" version)) | |
2392 | (sha256 | |
2393 | (base32 | |
eb3fd382 | 2394 | "0r6r1adj20x3ckm0dlipxlf1rzngr92xsxxpy81mqxf4jpmyr8gj")))) |
3d13b448 RW |
2395 | (build-system r-build-system) |
2396 | (propagated-inputs | |
2397 | `(("r-s4vectors" ,r-s4vectors) | |
2398 | ("r-iranges" ,r-iranges) | |
2399 | ("r-genomicranges" ,r-genomicranges) | |
2400 | ("r-biocgenerics" ,r-biocgenerics))) | |
2401 | (home-page "https://bioconductor.org/packages/copynumber") | |
2402 | (synopsis "Segmentation of single- and multi-track copy number data") | |
2403 | (description | |
2404 | "This package segments single- and multi-track copy number data by a | |
2405 | penalized least squares regression method.") | |
2406 | (license license:artistic2.0))) | |
2407 | ||
c18dccff RW |
2408 | (define-public r-dnacopy |
2409 | (package | |
2410 | (name "r-dnacopy") | |
bba70cda | 2411 | (version "1.60.0") |
c18dccff RW |
2412 | (source |
2413 | (origin | |
2414 | (method url-fetch) | |
2415 | (uri (bioconductor-uri "DNAcopy" version)) | |
2416 | (sha256 | |
2417 | (base32 | |
bba70cda | 2418 | "119z5lqhhw9ppg6s4dvbxk1kxf3wc55ibpm9b88c91s04yd7m9yw")))) |
c18dccff RW |
2419 | (properties `((upstream-name . "DNAcopy"))) |
2420 | (build-system r-build-system) | |
2421 | (native-inputs `(("gfortran" ,gfortran))) | |
2422 | (home-page "https://bioconductor.org/packages/DNAcopy") | |
2423 | (synopsis "DNA copy number data analysis") | |
2424 | (description | |
2425 | "This package implements the @dfn{circular binary segmentation} (CBS) | |
2426 | algorithm to segment DNA copy number data and identify genomic regions with | |
2427 | abnormal copy number.") | |
2428 | (license license:gpl2+))) | |
3a0babac RW |
2429 | |
2430 | ;; This is a CRAN package, but it uncharacteristically depends on a | |
2431 | ;; Bioconductor package. | |
2432 | (define-public r-htscluster | |
2433 | (package | |
2434 | (name "r-htscluster") | |
2435 | (version "2.0.8") | |
2436 | (source | |
2437 | (origin | |
2438 | (method url-fetch) | |
2439 | (uri (cran-uri "HTSCluster" version)) | |
2440 | (sha256 | |
2441 | (base32 | |
2442 | "0wnbfh6hdx8692jilgmv8sys1zm6fqc6mim7vvjhyqlmpm8gm0kg")))) | |
2443 | (properties `((upstream-name . "HTSCluster"))) | |
2444 | (build-system r-build-system) | |
2445 | (propagated-inputs | |
2446 | `(("r-capushe" ,r-capushe) | |
2447 | ("r-edger" ,r-edger) | |
2448 | ("r-plotrix" ,r-plotrix))) | |
2449 | (home-page "https://cran.r-project.org/web/packages/HTSCluster") | |
2450 | (synopsis "Clustering high-throughput transcriptome sequencing (HTS) data") | |
2451 | (description | |
2452 | "This package provides a Poisson mixture model is implemented to cluster | |
2453 | genes from high-throughput transcriptome sequencing (RNA-seq) data. Parameter | |
2454 | estimation is performed using either the EM or CEM algorithm, and the slope | |
2455 | heuristics are used for model selection (i.e., to choose the number of | |
2456 | clusters).") | |
2457 | (license license:gpl3+))) | |
173c9960 RW |
2458 | |
2459 | (define-public r-deds | |
2460 | (package | |
2461 | (name "r-deds") | |
96030bf7 | 2462 | (version "1.60.0") |
173c9960 RW |
2463 | (source |
2464 | (origin | |
2465 | (method url-fetch) | |
2466 | (uri (bioconductor-uri "DEDS" version)) | |
2467 | (sha256 | |
2468 | (base32 | |
96030bf7 | 2469 | "0vzsmah2lhxf8k6n4d0i4j609sbvygmb6ii2ridg9z3nskwkrhp8")))) |
173c9960 RW |
2470 | (properties `((upstream-name . "DEDS"))) |
2471 | (build-system r-build-system) | |
2472 | (home-page "https://bioconductor.org/packages/DEDS/") | |
2473 | (synopsis "Differential expression via distance summary for microarray data") | |
2474 | (description | |
2475 | "This library contains functions that calculate various statistics of | |
2476 | differential expression for microarray data, including t statistics, fold | |
2477 | change, F statistics, SAM, moderated t and F statistics and B statistics. It | |
2478 | also implements a new methodology called DEDS (Differential Expression via | |
2479 | Distance Summary), which selects differentially expressed genes by integrating | |
2480 | and summarizing a set of statistics using a weighted distance approach.") | |
2481 | ;; Any version of the LGPL. | |
2482 | (license license:lgpl3+))) | |
7ed869f7 RW |
2483 | |
2484 | ;; This is a CRAN package, but since it depends on a Bioconductor package we | |
2485 | ;; put it here. | |
2486 | (define-public r-nbpseq | |
2487 | (package | |
2488 | (name "r-nbpseq") | |
2489 | (version "0.3.0") | |
2490 | (source | |
2491 | (origin | |
2492 | (method url-fetch) | |
2493 | (uri (cran-uri "NBPSeq" version)) | |
2494 | (sha256 | |
2495 | (base32 | |
2496 | "0l4ylxhs2k9ww21jjqs67fygk92avdchhx2y1ixzl7yr2yh1y9by")))) | |
2497 | (properties `((upstream-name . "NBPSeq"))) | |
2498 | (build-system r-build-system) | |
2499 | (propagated-inputs | |
2500 | `(("r-qvalue" ,r-qvalue))) | |
2501 | (home-page "https://cran.r-project.org/web/packages/NBPSeq") | |
2502 | (synopsis "Negative binomial models for RNA-Seq data") | |
2503 | (description | |
2504 | "This package provides negative binomial models for two-group comparisons | |
2505 | and regression inferences from RNA-sequencing data.") | |
2506 | (license license:gpl2))) | |
3087a2f3 RW |
2507 | |
2508 | (define-public r-ebseq | |
2509 | (package | |
2510 | (name "r-ebseq") | |
a9649c41 | 2511 | (version "1.26.0") |
3087a2f3 RW |
2512 | (source |
2513 | (origin | |
2514 | (method url-fetch) | |
2515 | (uri (bioconductor-uri "EBSeq" version)) | |
2516 | (sha256 | |
2517 | (base32 | |
a9649c41 | 2518 | "0ay1vcccpc29r3vinlnwp9256345bfb346kg2y11kib4bnrabjb6")))) |
3087a2f3 RW |
2519 | (properties `((upstream-name . "EBSeq"))) |
2520 | (build-system r-build-system) | |
2521 | (propagated-inputs | |
2522 | `(("r-blockmodeling" ,r-blockmodeling) | |
2523 | ("r-gplots" ,r-gplots) | |
2524 | ("r-testthat" ,r-testthat))) | |
2525 | (home-page "https://bioconductor.org/packages/EBSeq") | |
2526 | (synopsis "Differential expression analysis of RNA-seq data") | |
2527 | (description | |
2528 | "This package provides tools for differential expression analysis at both | |
2529 | gene and isoform level using RNA-seq data") | |
2530 | (license license:artistic2.0))) | |
2cb71d81 RW |
2531 | |
2532 | (define-public r-lpsymphony | |
2533 | (package | |
2534 | (name "r-lpsymphony") | |
153dc51b | 2535 | (version "1.14.0") |
2cb71d81 RW |
2536 | (source |
2537 | (origin | |
2538 | (method url-fetch) | |
2539 | (uri (bioconductor-uri "lpsymphony" version)) | |
2540 | (sha256 | |
2541 | (base32 | |
153dc51b | 2542 | "0j5j9kggh3l61vp6hpnqf45d5kzifksaj0sqhvs1zahmx2c1gfdv")))) |
2cb71d81 RW |
2543 | (build-system r-build-system) |
2544 | (inputs | |
2545 | `(("gfortran" ,gfortran) | |
2546 | ("zlib" ,zlib))) | |
2547 | (native-inputs | |
2548 | `(("pkg-config" ,pkg-config))) | |
c756328e | 2549 | (home-page "https://r-forge.r-project.org/projects/rsymphony") |
2cb71d81 RW |
2550 | (synopsis "Symphony integer linear programming solver in R") |
2551 | (description | |
2552 | "This package was derived from Rsymphony. The package provides an R | |
2553 | interface to SYMPHONY, a linear programming solver written in C++. The main | |
2554 | difference between this package and Rsymphony is that it includes the solver | |
2555 | source code, while Rsymphony expects to find header and library files on the | |
2556 | users' system. Thus the intention of @code{lpsymphony} is to provide an easy | |
2557 | to install interface to SYMPHONY.") | |
2558 | ;; Symphony 5.4 or later is distributed under the terms of the EPL 1.0. | |
2559 | ;; lpsimphony is released under the same terms. | |
2560 | (license license:epl1.0))) | |
704de8f5 RW |
2561 | |
2562 | (define-public r-ihw | |
2563 | (package | |
2564 | (name "r-ihw") | |
0383bd05 | 2565 | (version "1.14.0") |
704de8f5 RW |
2566 | (source |
2567 | (origin | |
2568 | (method url-fetch) | |
2569 | (uri (bioconductor-uri "IHW" version)) | |
2570 | (sha256 | |
2571 | (base32 | |
0383bd05 | 2572 | "0rnw7r9pylpj3a5graavcpiqv2v67rv2a4dlcynkf4ihpxs4bg8x")))) |
704de8f5 RW |
2573 | (properties `((upstream-name . "IHW"))) |
2574 | (build-system r-build-system) | |
2575 | (propagated-inputs | |
2576 | `(("r-biocgenerics" ,r-biocgenerics) | |
2577 | ("r-fdrtool" ,r-fdrtool) | |
2578 | ("r-lpsymphony" ,r-lpsymphony) | |
2579 | ("r-slam" ,r-slam))) | |
2580 | (home-page "https://bioconductor.org/packages/IHW") | |
2581 | (synopsis "Independent hypothesis weighting") | |
2582 | (description | |
2583 | "@dfn{Independent hypothesis weighting} (IHW) is a multiple testing | |
2584 | procedure that increases power compared to the method of Benjamini and | |
2585 | Hochberg by assigning data-driven weights to each hypothesis. The input to | |
2586 | IHW is a two-column table of p-values and covariates. The covariate can be | |
2587 | any continuous-valued or categorical variable that is thought to be | |
2588 | informative on the statistical properties of each hypothesis test, while it is | |
2589 | independent of the p-value under the null hypothesis.") | |
2590 | (license license:artistic2.0))) | |
251e0830 RW |
2591 | |
2592 | (define-public r-icobra | |
2593 | (package | |
2594 | (name "r-icobra") | |
a5cc1f10 | 2595 | (version "1.14.0") |
251e0830 RW |
2596 | (source |
2597 | (origin | |
2598 | (method url-fetch) | |
2599 | (uri (bioconductor-uri "iCOBRA" version)) | |
2600 | (sha256 | |
2601 | (base32 | |
a5cc1f10 | 2602 | "1l0yr2grpwmr3pc5h50p1j4nxyb1ddmc55l7rhxpp4igh4fq1avz")))) |
251e0830 RW |
2603 | (properties `((upstream-name . "iCOBRA"))) |
2604 | (build-system r-build-system) | |
2605 | (propagated-inputs | |
2606 | `(("r-dplyr" ,r-dplyr) | |
2607 | ("r-dt" ,r-dt) | |
2608 | ("r-ggplot2" ,r-ggplot2) | |
2609 | ("r-limma" ,r-limma) | |
2610 | ("r-reshape2" ,r-reshape2) | |
2611 | ("r-rocr" ,r-rocr) | |
2612 | ("r-scales" ,r-scales) | |
2613 | ("r-shiny" ,r-shiny) | |
2614 | ("r-shinybs" ,r-shinybs) | |
2615 | ("r-shinydashboard" ,r-shinydashboard) | |
2616 | ("r-upsetr" ,r-upsetr))) | |
2617 | (home-page "https://bioconductor.org/packages/iCOBRA") | |
2618 | (synopsis "Comparison and visualization of ranking and assignment methods") | |
2619 | (description | |
2620 | "This package provides functions for calculation and visualization of | |
2621 | performance metrics for evaluation of ranking and binary | |
2622 | classification (assignment) methods. It also contains a Shiny application for | |
2623 | interactive exploration of results.") | |
2624 | (license license:gpl2+))) | |
925fcdbb RW |
2625 | |
2626 | (define-public r-mast | |
2627 | (package | |
2628 | (name "r-mast") | |
dc5237f8 | 2629 | (version "1.12.0") |
925fcdbb RW |
2630 | (source |
2631 | (origin | |
2632 | (method url-fetch) | |
2633 | (uri (bioconductor-uri "MAST" version)) | |
2634 | (sha256 | |
2635 | (base32 | |
dc5237f8 | 2636 | "1l78rrwkzyswpj6pgc9z8290fqrk4akba76invkkazpyh91r8gga")))) |
925fcdbb RW |
2637 | (properties `((upstream-name . "MAST"))) |
2638 | (build-system r-build-system) | |
2639 | (propagated-inputs | |
2640 | `(("r-abind" ,r-abind) | |
2641 | ("r-biobase" ,r-biobase) | |
2642 | ("r-biocgenerics" ,r-biocgenerics) | |
2643 | ("r-data-table" ,r-data-table) | |
2644 | ("r-ggplot2" ,r-ggplot2) | |
2645 | ("r-plyr" ,r-plyr) | |
2646 | ("r-progress" ,r-progress) | |
2647 | ("r-reshape2" ,r-reshape2) | |
2648 | ("r-s4vectors" ,r-s4vectors) | |
2649 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2650 | ("r-stringr" ,r-stringr) | |
2651 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2652 | (home-page "https://github.com/RGLab/MAST/") | |
2653 | (synopsis "Model-based analysis of single cell transcriptomics") | |
2654 | (description | |
2655 | "This package provides methods and models for handling zero-inflated | |
2656 | single cell assay data.") | |
2657 | (license license:gpl2+))) | |
2d7627cf RW |
2658 | |
2659 | (define-public r-monocle | |
2660 | (package | |
2661 | (name "r-monocle") | |
9732e690 | 2662 | (version "2.14.0") |
2d7627cf RW |
2663 | (source |
2664 | (origin | |
2665 | (method url-fetch) | |
2666 | (uri (bioconductor-uri "monocle" version)) | |
2667 | (sha256 | |
2668 | (base32 | |
9732e690 | 2669 | "18b9y592q48mbcp5w095qs1kaklq64v6dcnlpqhv3rwxvywygsz2")))) |
2d7627cf RW |
2670 | (build-system r-build-system) |
2671 | (propagated-inputs | |
2672 | `(("r-biobase" ,r-biobase) | |
2673 | ("r-biocgenerics" ,r-biocgenerics) | |
2674 | ("r-biocviews" ,r-biocviews) | |
2675 | ("r-cluster" ,r-cluster) | |
2676 | ("r-combinat" ,r-combinat) | |
2677 | ("r-ddrtree" ,r-ddrtree) | |
2678 | ("r-densityclust" ,r-densityclust) | |
2679 | ("r-dplyr" ,r-dplyr) | |
2680 | ("r-fastica" ,r-fastica) | |
2681 | ("r-ggplot2" ,r-ggplot2) | |
2682 | ("r-hsmmsinglecell" ,r-hsmmsinglecell) | |
2683 | ("r-igraph" ,r-igraph) | |
2684 | ("r-irlba" ,r-irlba) | |
2685 | ("r-limma" ,r-limma) | |
2686 | ("r-mass" ,r-mass) | |
2687 | ("r-matrix" ,r-matrix) | |
2688 | ("r-matrixstats" ,r-matrixstats) | |
2689 | ("r-pheatmap" ,r-pheatmap) | |
2690 | ("r-plyr" ,r-plyr) | |
2691 | ("r-proxy" ,r-proxy) | |
2692 | ("r-qlcmatrix" ,r-qlcmatrix) | |
2693 | ("r-rann" ,r-rann) | |
2694 | ("r-rcpp" ,r-rcpp) | |
2695 | ("r-reshape2" ,r-reshape2) | |
2696 | ("r-rtsne" ,r-rtsne) | |
2697 | ("r-slam" ,r-slam) | |
2698 | ("r-stringr" ,r-stringr) | |
2699 | ("r-tibble" ,r-tibble) | |
2700 | ("r-vgam" ,r-vgam) | |
2701 | ("r-viridis" ,r-viridis))) | |
2702 | (home-page "https://bioconductor.org/packages/monocle") | |
2703 | (synopsis "Clustering, differential expression, and trajectory analysis for single-cell RNA-Seq") | |
2704 | (description | |
2705 | "Monocle performs differential expression and time-series analysis for | |
2706 | single-cell expression experiments. It orders individual cells according to | |
2707 | progress through a biological process, without knowing ahead of time which | |
2708 | genes define progress through that process. Monocle also performs | |
2709 | differential expression analysis, clustering, visualization, and other useful | |
2710 | tasks on single cell expression data. It is designed to work with RNA-Seq and | |
2711 | qPCR data, but could be used with other types as well.") | |
2712 | (license license:artistic2.0))) | |
6213e441 | 2713 | |
b2dce6b5 RW |
2714 | (define-public r-monocle3 |
2715 | (package | |
2716 | (name "r-monocle3") | |
2717 | (version "0.1.2") | |
2718 | (source | |
2719 | (origin | |
2720 | (method git-fetch) | |
2721 | (uri (git-reference | |
2722 | (url "https://github.com/cole-trapnell-lab/monocle3.git") | |
2723 | (commit version))) | |
2724 | (file-name (git-file-name name version)) | |
2725 | (sha256 | |
2726 | (base32 | |
2727 | "1cjxqfw3qvy269hsf5v80d4kshl932wrl949iayas02saj6f70ls")))) | |
2728 | (build-system r-build-system) | |
2729 | (propagated-inputs | |
2730 | `(("r-biobase" ,r-biobase) | |
2731 | ("r-biocgenerics" ,r-biocgenerics) | |
2732 | ("r-delayedmatrixstats" ,r-delayedmatrixstats) | |
2733 | ("r-dplyr" ,r-dplyr) | |
2734 | ("r-ggplot2" ,r-ggplot2) | |
2735 | ("r-ggrepel" ,r-ggrepel) | |
2736 | ("r-grr" ,r-grr) | |
2737 | ("r-htmlwidgets" ,r-htmlwidgets) | |
2738 | ("r-igraph" ,r-igraph) | |
2739 | ("r-irlba" ,r-irlba) | |
2740 | ("r-limma" ,r-limma) | |
2741 | ("r-lmtest" ,r-lmtest) | |
2742 | ("r-mass" ,r-mass) | |
2743 | ("r-matrix" ,r-matrix) | |
2744 | ("r-matrix-utils" ,r-matrix-utils) | |
2745 | ("r-pbapply" ,r-pbapply) | |
2746 | ("r-pbmcapply" ,r-pbmcapply) | |
2747 | ("r-pheatmap" ,r-pheatmap) | |
2748 | ("r-plotly" ,r-plotly) | |
2749 | ("r-pryr" ,r-pryr) | |
2750 | ("r-proxy" ,r-proxy) | |
2751 | ("r-pscl" ,r-pscl) | |
2752 | ("r-purrr" ,r-purrr) | |
2753 | ("r-rann" ,r-rann) | |
2754 | ("r-rcpp" ,r-rcpp) | |
2755 | ("r-rcppparallel" ,r-rcppparallel) | |
2756 | ("r-reshape2" ,r-reshape2) | |
2757 | ("r-reticulate" ,r-reticulate) | |
2758 | ("r-rhpcblasctl" ,r-rhpcblasctl) | |
2759 | ("r-rtsne" ,r-rtsne) | |
2760 | ("r-shiny" ,r-shiny) | |
2761 | ("r-slam" ,r-slam) | |
2762 | ("r-spdep" ,r-spdep) | |
2763 | ("r-speedglm" ,r-speedglm) | |
2764 | ("r-stringr" ,r-stringr) | |
2765 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2766 | ("r-tibble" ,r-tibble) | |
2767 | ("r-tidyr" ,r-tidyr) | |
2768 | ("r-uwot" ,r-uwot) | |
2769 | ("r-viridis" ,r-viridis))) | |
2770 | (home-page "https://github.com/cole-trapnell-lab/monocle3") | |
2771 | (synopsis "Analysis toolkit for single-cell RNA-Seq data") | |
2772 | (description | |
2773 | "Monocle 3 is an analysis toolkit for single-cell RNA-Seq experiments.") | |
2774 | (license license:expat))) | |
2775 | ||
6213e441 RW |
2776 | (define-public r-noiseq |
2777 | (package | |
2778 | (name "r-noiseq") | |
81a125cd | 2779 | (version "2.30.0") |
6213e441 RW |
2780 | (source |
2781 | (origin | |
2782 | (method url-fetch) | |
2783 | (uri (bioconductor-uri "NOISeq" version)) | |
2784 | (sha256 | |
2785 | (base32 | |
81a125cd | 2786 | "1a8p66hhnwmay0rjabwq7356wr93yn33nqgr9rr7whpp9nls1hg4")))) |
6213e441 RW |
2787 | (properties `((upstream-name . "NOISeq"))) |
2788 | (build-system r-build-system) | |
2789 | (propagated-inputs | |
2790 | `(("r-biobase" ,r-biobase) | |
2791 | ("r-matrix" ,r-matrix))) | |
2792 | (home-page "https://bioconductor.org/packages/NOISeq") | |
2793 | (synopsis "Exploratory analysis and differential expression for RNA-seq data") | |
2794 | (description | |
2795 | "This package provides tools to support the analysis of RNA-seq | |
2796 | expression data or other similar kind of data. It provides exploratory plots | |
2797 | to evaluate saturation, count distribution, expression per chromosome, type of | |
2798 | detected features, features length, etc. It also supports the analysis of | |
2799 | differential expression between two experimental conditions with no parametric | |
2800 | assumptions.") | |
2801 | (license license:artistic2.0))) | |
b409c357 RW |
2802 | |
2803 | (define-public r-scdd | |
2804 | (package | |
2805 | (name "r-scdd") | |
2f223b21 | 2806 | (version "1.10.0") |
b409c357 RW |
2807 | (source |
2808 | (origin | |
2809 | (method url-fetch) | |
2810 | (uri (bioconductor-uri "scDD" version)) | |
2811 | (sha256 | |
2812 | (base32 | |
2f223b21 | 2813 | "0nk0qq664zs7dnlcamdkrrhvll01p7f96jj3igbxxlzj3dvr58w4")))) |
b409c357 RW |
2814 | (properties `((upstream-name . "scDD"))) |
2815 | (build-system r-build-system) | |
2816 | (propagated-inputs | |
2817 | `(("r-arm" ,r-arm) | |
2818 | ("r-biocparallel" ,r-biocparallel) | |
2819 | ("r-ebseq" ,r-ebseq) | |
2820 | ("r-fields" ,r-fields) | |
2821 | ("r-ggplot2" ,r-ggplot2) | |
2822 | ("r-mclust" ,r-mclust) | |
2823 | ("r-outliers" ,r-outliers) | |
2824 | ("r-s4vectors" ,r-s4vectors) | |
2825 | ("r-scran" ,r-scran) | |
2826 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2827 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2828 | (home-page "https://github.com/kdkorthauer/scDD") | |
2829 | (synopsis "Mixture modeling of single-cell RNA-seq data") | |
2830 | (description | |
2831 | "This package implements a method to analyze single-cell RNA-seq data | |
2832 | utilizing flexible Dirichlet Process mixture models. Genes with differential | |
2833 | distributions of expression are classified into several interesting patterns | |
2834 | of differences between two conditions. The package also includes functions | |
2835 | for simulating data with these patterns from negative binomial | |
2836 | distributions.") | |
2837 | (license license:gpl2))) | |
f0887757 RW |
2838 | |
2839 | (define-public r-scone | |
2840 | (package | |
2841 | (name "r-scone") | |
048a43d6 | 2842 | (version "1.10.0") |
f0887757 RW |
2843 | (source |
2844 | (origin | |
2845 | (method url-fetch) | |
2846 | (uri (bioconductor-uri "scone" version)) | |
2847 | (sha256 | |
2848 | (base32 | |
048a43d6 | 2849 | "1hfsbnix0y9ad6bj0d8q2aw13pb3vjcaa0dfwxxapzl90zwbsjhp")))) |
f0887757 RW |
2850 | (build-system r-build-system) |
2851 | (propagated-inputs | |
2852 | `(("r-aroma-light" ,r-aroma-light) | |
2853 | ("r-biocparallel" ,r-biocparallel) | |
2854 | ("r-boot" ,r-boot) | |
2855 | ("r-class" ,r-class) | |
2856 | ("r-cluster" ,r-cluster) | |
2857 | ("r-compositions" ,r-compositions) | |
2858 | ("r-diptest" ,r-diptest) | |
2859 | ("r-edger" ,r-edger) | |
2860 | ("r-fpc" ,r-fpc) | |
2861 | ("r-gplots" ,r-gplots) | |
2862 | ("r-hexbin" ,r-hexbin) | |
2863 | ("r-limma" ,r-limma) | |
2864 | ("r-matrixstats" ,r-matrixstats) | |
2865 | ("r-mixtools" ,r-mixtools) | |
2866 | ("r-rarpack" ,r-rarpack) | |
2867 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
2868 | ("r-rhdf5" ,r-rhdf5) | |
2869 | ("r-ruvseq" ,r-ruvseq) | |
2870 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2871 | (home-page "https://bioconductor.org/packages/scone") | |
2872 | (synopsis "Single cell overview of normalized expression data") | |
2873 | (description | |
2874 | "SCONE is an R package for comparing and ranking the performance of | |
2875 | different normalization schemes for single-cell RNA-seq and other | |
2876 | high-throughput analyses.") | |
2877 | (license license:artistic2.0))) | |
f9201d67 RW |
2878 | |
2879 | (define-public r-geoquery | |
2880 | (package | |
2881 | (name "r-geoquery") | |
db85744e | 2882 | (version "2.54.1") |
f9201d67 RW |
2883 | (source |
2884 | (origin | |
2885 | (method url-fetch) | |
2886 | (uri (bioconductor-uri "GEOquery" version)) | |
2887 | (sha256 | |
2888 | (base32 | |
db85744e | 2889 | "0j8mlldy7dc38fx5zwj6z6l4b9bhvrn8sil3z8asnd4ic7w9ifx5")))) |
f9201d67 RW |
2890 | (properties `((upstream-name . "GEOquery"))) |
2891 | (build-system r-build-system) | |
2892 | (propagated-inputs | |
2893 | `(("r-biobase" ,r-biobase) | |
2894 | ("r-dplyr" ,r-dplyr) | |
2895 | ("r-httr" ,r-httr) | |
2896 | ("r-limma" ,r-limma) | |
2897 | ("r-magrittr" ,r-magrittr) | |
2898 | ("r-readr" ,r-readr) | |
2899 | ("r-tidyr" ,r-tidyr) | |
2900 | ("r-xml2" ,r-xml2))) | |
2901 | (home-page "https://github.com/seandavi/GEOquery/") | |
2902 | (synopsis "Get data from NCBI Gene Expression Omnibus (GEO)") | |
2903 | (description | |
2904 | "The NCBI Gene Expression Omnibus (GEO) is a public repository of | |
2905 | microarray data. Given the rich and varied nature of this resource, it is | |
2906 | only natural to want to apply BioConductor tools to these data. GEOquery is | |
2907 | the bridge between GEO and BioConductor.") | |
2908 | (license license:gpl2))) | |
eed6ff03 RW |
2909 | |
2910 | (define-public r-illuminaio | |
2911 | (package | |
2912 | (name "r-illuminaio") | |
418d7214 | 2913 | (version "0.28.0") |
eed6ff03 RW |
2914 | (source |
2915 | (origin | |
2916 | (method url-fetch) | |
2917 | (uri (bioconductor-uri "illuminaio" version)) | |
2918 | (sha256 | |
2919 | (base32 | |
418d7214 | 2920 | "1psza8jq6h8fv2rm91ah67dgjlnj1l80yracwgdl1agd0ycv90sh")))) |
eed6ff03 RW |
2921 | (build-system r-build-system) |
2922 | (propagated-inputs | |
2923 | `(("r-base64" ,r-base64))) | |
2924 | (home-page "https://github.com/HenrikBengtsson/illuminaio/") | |
2925 | (synopsis "Parse Illumina microarray output files") | |
2926 | (description | |
2927 | "This package provides tools for parsing Illumina's microarray output | |
2928 | files, including IDAT.") | |
2929 | (license license:gpl2))) | |
f4eac096 RW |
2930 | |
2931 | (define-public r-siggenes | |
2932 | (package | |
2933 | (name "r-siggenes") | |
b4ee4148 | 2934 | (version "1.60.0") |
f4eac096 RW |
2935 | (source |
2936 | (origin | |
2937 | (method url-fetch) | |
2938 | (uri (bioconductor-uri "siggenes" version)) | |
2939 | (sha256 | |
2940 | (base32 | |
b4ee4148 | 2941 | "03lmq3hqprwps4miynl2vhqi3v4als5vqmz4lb19lk5a4zja72b4")))) |
f4eac096 RW |
2942 | (build-system r-build-system) |
2943 | (propagated-inputs | |
2944 | `(("r-biobase" ,r-biobase) | |
409f4dd6 RW |
2945 | ("r-multtest" ,r-multtest) |
2946 | ("r-scrime" ,r-scrime))) | |
f4eac096 RW |
2947 | (home-page "https://bioconductor.org/packages/siggenes/") |
2948 | (synopsis | |
2949 | "Multiple testing using SAM and Efron's empirical Bayes approaches") | |
2950 | (description | |
2951 | "This package provides tools for the identification of differentially | |
2952 | expressed genes and estimation of the @dfn{False Discovery Rate} (FDR) using | |
2953 | both the Significance Analysis of Microarrays (SAM) and the @dfn{Empirical | |
2954 | Bayes Analyses of Microarrays} (EBAM).") | |
2955 | (license license:lgpl2.0+))) | |
34a24f95 RW |
2956 | |
2957 | (define-public r-bumphunter | |
2958 | (package | |
2959 | (name "r-bumphunter") | |
4efdac56 | 2960 | (version "1.28.0") |
34a24f95 RW |
2961 | (source |
2962 | (origin | |
2963 | (method url-fetch) | |
2964 | (uri (bioconductor-uri "bumphunter" version)) | |
2965 | (sha256 | |
2966 | (base32 | |
4efdac56 | 2967 | "1p3gwb954zns61d1pwgkplxnvgk2lixrl93kkkf439wa3vlgsnjv")))) |
34a24f95 RW |
2968 | (build-system r-build-system) |
2969 | (propagated-inputs | |
2970 | `(("r-annotationdbi" ,r-annotationdbi) | |
2971 | ("r-biocgenerics" ,r-biocgenerics) | |
2972 | ("r-dorng" ,r-dorng) | |
2973 | ("r-foreach" ,r-foreach) | |
2974 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2975 | ("r-genomicfeatures" ,r-genomicfeatures) | |
2976 | ("r-genomicranges" ,r-genomicranges) | |
2977 | ("r-iranges" ,r-iranges) | |
2978 | ("r-iterators" ,r-iterators) | |
2979 | ("r-limma" ,r-limma) | |
2980 | ("r-locfit" ,r-locfit) | |
2981 | ("r-matrixstats" ,r-matrixstats) | |
2982 | ("r-s4vectors" ,r-s4vectors))) | |
2983 | (home-page "https://github.com/ririzarr/bumphunter") | |
2984 | (synopsis "Find bumps in genomic data") | |
2985 | (description | |
2986 | "This package provides tools for finding bumps in genomic data in order | |
2987 | to identify differentially methylated regions in epigenetic epidemiology | |
2988 | studies.") | |
2989 | (license license:artistic2.0))) | |
0fbaf195 RW |
2990 | |
2991 | (define-public r-minfi | |
2992 | (package | |
2993 | (name "r-minfi") | |
dfd4287c | 2994 | (version "1.32.0") |
0fbaf195 RW |
2995 | (source |
2996 | (origin | |
2997 | (method url-fetch) | |
2998 | (uri (bioconductor-uri "minfi" version)) | |
2999 | (sha256 | |
3000 | (base32 | |
dfd4287c | 3001 | "177isdvcq2476xybvfbh7x11qsj5nzckgh3b6p156wlx9ap9dvl3")))) |
0fbaf195 RW |
3002 | (build-system r-build-system) |
3003 | (propagated-inputs | |
3004 | `(("r-beanplot" ,r-beanplot) | |
3005 | ("r-biobase" ,r-biobase) | |
3006 | ("r-biocgenerics" ,r-biocgenerics) | |
3007 | ("r-biocparallel" ,r-biocparallel) | |
3008 | ("r-biostrings" ,r-biostrings) | |
3009 | ("r-bumphunter" ,r-bumphunter) | |
3010 | ("r-data-table" ,r-data-table) | |
3011 | ("r-delayedarray" ,r-delayedarray) | |
3012 | ("r-delayedmatrixstats" ,r-delayedmatrixstats) | |
3013 | ("r-genefilter" ,r-genefilter) | |
3014 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3015 | ("r-genomicranges" ,r-genomicranges) | |
3016 | ("r-geoquery" ,r-geoquery) | |
3017 | ("r-hdf5array" ,r-hdf5array) | |
3018 | ("r-illuminaio" ,r-illuminaio) | |
3019 | ("r-iranges" ,r-iranges) | |
3020 | ("r-lattice" ,r-lattice) | |
3021 | ("r-limma" ,r-limma) | |
3022 | ("r-mass" ,r-mass) | |
3023 | ("r-mclust" ,r-mclust) | |
3024 | ("r-nlme" ,r-nlme) | |
3025 | ("r-nor1mix" ,r-nor1mix) | |
3026 | ("r-preprocesscore" ,r-preprocesscore) | |
3027 | ("r-quadprog" ,r-quadprog) | |
3028 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
3029 | ("r-reshape" ,r-reshape) | |
3030 | ("r-s4vectors" ,r-s4vectors) | |
3031 | ("r-siggenes" ,r-siggenes) | |
3032 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
3033 | (home-page "https://github.com/hansenlab/minfi") | |
3034 | (synopsis "Analyze Illumina Infinium DNA methylation arrays") | |
3035 | (description | |
3036 | "This package provides tools to analyze and visualize Illumina Infinium | |
3037 | methylation arrays.") | |
3038 | (license license:artistic2.0))) | |
5ec5ba02 RW |
3039 | |
3040 | (define-public r-methylumi | |
3041 | (package | |
3042 | (name "r-methylumi") | |
b57cffb9 | 3043 | (version "2.32.0") |
5ec5ba02 RW |
3044 | (source |
3045 | (origin | |
3046 | (method url-fetch) | |
3047 | (uri (bioconductor-uri "methylumi" version)) | |
3048 | (sha256 | |
3049 | (base32 | |
b57cffb9 | 3050 | "0zd4h6n37v3z0mas69z2xsf5s0naih828987m8v0g9hhq4f6hf5w")))) |
5ec5ba02 RW |
3051 | (build-system r-build-system) |
3052 | (propagated-inputs | |
3053 | `(("r-annotate" ,r-annotate) | |
3054 | ("r-annotationdbi" ,r-annotationdbi) | |
3055 | ("r-biobase" ,r-biobase) | |
3056 | ("r-biocgenerics" ,r-biocgenerics) | |
3057 | ("r-fdb-infiniummethylation-hg19" ,r-fdb-infiniummethylation-hg19) | |
3058 | ("r-genefilter" ,r-genefilter) | |
3059 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3060 | ("r-genomicranges" ,r-genomicranges) | |
3061 | ("r-ggplot2" ,r-ggplot2) | |
3062 | ("r-illuminaio" ,r-illuminaio) | |
3063 | ("r-iranges" ,r-iranges) | |
3064 | ("r-lattice" ,r-lattice) | |
3065 | ("r-matrixstats" ,r-matrixstats) | |
3066 | ("r-minfi" ,r-minfi) | |
3067 | ("r-reshape2" ,r-reshape2) | |
3068 | ("r-s4vectors" ,r-s4vectors) | |
3069 | ("r-scales" ,r-scales) | |
3070 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
3071 | (home-page "https://bioconductor.org/packages/methylumi") | |
3072 | (synopsis "Handle Illumina methylation data") | |
3073 | (description | |
3074 | "This package provides classes for holding and manipulating Illumina | |
3075 | methylation data. Based on eSet, it can contain MIAME information, sample | |
3076 | information, feature information, and multiple matrices of data. An | |
3077 | \"intelligent\" import function, methylumiR can read the Illumina text files | |
3078 | and create a MethyLumiSet. methylumIDAT can directly read raw IDAT files from | |
3079 | HumanMethylation27 and HumanMethylation450 microarrays. Normalization, | |
3080 | background correction, and quality control features for GoldenGate, Infinium, | |
3081 | and Infinium HD arrays are also included.") | |
3082 | (license license:gpl2))) | |
09605cb2 RW |
3083 | |
3084 | (define-public r-lumi | |
3085 | (package | |
3086 | (name "r-lumi") | |
8f7bc872 | 3087 | (version "2.38.0") |
09605cb2 RW |
3088 | (source |
3089 | (origin | |
3090 | (method url-fetch) | |
3091 | (uri (bioconductor-uri "lumi" version)) | |
3092 | (sha256 | |
3093 | (base32 | |
8f7bc872 | 3094 | "0lgrqbdvp7ykcafc0bpnbcsf396na3jj5c35x9ysf5bpcas23nmm")))) |
09605cb2 RW |
3095 | (build-system r-build-system) |
3096 | (propagated-inputs | |
3097 | `(("r-affy" ,r-affy) | |
3098 | ("r-annotate" ,r-annotate) | |
3099 | ("r-annotationdbi" ,r-annotationdbi) | |
3100 | ("r-biobase" ,r-biobase) | |
3101 | ("r-dbi" ,r-dbi) | |
3102 | ("r-genomicfeatures" ,r-genomicfeatures) | |
3103 | ("r-genomicranges" ,r-genomicranges) | |
3104 | ("r-kernsmooth" ,r-kernsmooth) | |
3105 | ("r-lattice" ,r-lattice) | |
3106 | ("r-mass" ,r-mass) | |
3107 | ("r-methylumi" ,r-methylumi) | |
3108 | ("r-mgcv" ,r-mgcv) | |
3109 | ("r-nleqslv" ,r-nleqslv) | |
3110 | ("r-preprocesscore" ,r-preprocesscore) | |
3111 | ("r-rsqlite" ,r-rsqlite))) | |
3112 | (home-page "https://bioconductor.org/packages/lumi") | |
3113 | (synopsis "BeadArray-specific methods for Illumina methylation and expression microarrays") | |
3114 | (description | |
3115 | "The lumi package provides an integrated solution for the Illumina | |
3116 | microarray data analysis. It includes functions of Illumina | |
3117 | BeadStudio (GenomeStudio) data input, quality control, BeadArray-specific | |
3118 | variance stabilization, normalization and gene annotation at the probe level. | |
3119 | It also includes the functions of processing Illumina methylation microarrays, | |
3120 | especially Illumina Infinium methylation microarrays.") | |
3121 | (license license:lgpl2.0+))) | |
4291f36a RW |
3122 | |
3123 | (define-public r-linnorm | |
3124 | (package | |
3125 | (name "r-linnorm") | |
a2877d69 | 3126 | (version "2.10.0") |
4291f36a RW |
3127 | (source |
3128 | (origin | |
3129 | (method url-fetch) | |
3130 | (uri (bioconductor-uri "Linnorm" version)) | |
3131 | (sha256 | |
3132 | (base32 | |
a2877d69 | 3133 | "15mhwiqmp9m65zvrdbr2hhy3x81lf4jbwgjsf75g41if2v2g8x67")))) |
4291f36a RW |
3134 | (properties `((upstream-name . "Linnorm"))) |
3135 | (build-system r-build-system) | |
3136 | (propagated-inputs | |
3137 | `(("r-amap" ,r-amap) | |
3138 | ("r-apcluster" ,r-apcluster) | |
3139 | ("r-ellipse" ,r-ellipse) | |
3140 | ("r-fastcluster" ,r-fastcluster) | |
3141 | ("r-fpc" ,r-fpc) | |
3142 | ("r-ggdendro" ,r-ggdendro) | |
3143 | ("r-ggplot2" ,r-ggplot2) | |
3144 | ("r-gmodels" ,r-gmodels) | |
3145 | ("r-igraph" ,r-igraph) | |
3146 | ("r-limma" ,r-limma) | |
3147 | ("r-mass" ,r-mass) | |
3148 | ("r-mclust" ,r-mclust) | |
3149 | ("r-rcpp" ,r-rcpp) | |
3150 | ("r-rcpparmadillo" ,r-rcpparmadillo) | |
3151 | ("r-rtsne" ,r-rtsne) | |
3152 | ("r-statmod" ,r-statmod) | |
3153 | ("r-vegan" ,r-vegan) | |
3154 | ("r-zoo" ,r-zoo))) | |
3155 | (home-page "http://www.jjwanglab.org/Linnorm/") | |
3156 | (synopsis "Linear model and normality based transformation method") | |
3157 | (description | |
3158 | "Linnorm is an R package for the analysis of RNA-seq, scRNA-seq, ChIP-seq | |
3159 | count data or any large scale count data. It transforms such datasets for | |
3160 | parametric tests. In addition to the transformtion function (@code{Linnorm}), | |
3161 | the following pipelines are implemented: | |
3162 | ||
3163 | @enumerate | |
3164 | @item Library size/batch effect normalization (@code{Linnorm.Norm}) | |
3165 | @item Cell subpopluation analysis and visualization using t-SNE or PCA K-means | |
3166 | clustering or hierarchical clustering (@code{Linnorm.tSNE}, | |
3167 | @code{Linnorm.PCA}, @code{Linnorm.HClust}) | |
3168 | @item Differential expression analysis or differential peak detection using | |
3169 | limma (@code{Linnorm.limma}) | |
3170 | @item Highly variable gene discovery and visualization (@code{Linnorm.HVar}) | |
3171 | @item Gene correlation network analysis and visualization (@code{Linnorm.Cor}) | |
3172 | @item Stable gene selection for scRNA-seq data; for users without or who do | |
3173 | not want to rely on spike-in genes (@code{Linnorm.SGenes}) | |
3174 | @item Data imputation (@code{Linnorm.DataImput}). | |
3175 | @end enumerate | |
3176 | ||
3177 | Linnorm can work with raw count, CPM, RPKM, FPKM and TPM. Additionally, the | |
3178 | @code{RnaXSim} function is included for simulating RNA-seq data for the | |
3179 | evaluation of DEG analysis methods.") | |
3180 | (license license:expat))) | |
e4a17532 RW |
3181 | |
3182 | (define-public r-ioniser | |
3183 | (package | |
3184 | (name "r-ioniser") | |
1b890c32 | 3185 | (version "2.10.0") |
e4a17532 RW |
3186 | (source |
3187 | (origin | |
3188 | (method url-fetch) | |
3189 | (uri (bioconductor-uri "IONiseR" version)) | |
3190 | (sha256 | |
3191 | (base32 | |
1b890c32 | 3192 | "1c265bzh923i9mw83mjpj0bzbkixbs6sg1h1z51y9xjkakdgg90f")))) |
e4a17532 RW |
3193 | (properties `((upstream-name . "IONiseR"))) |
3194 | (build-system r-build-system) | |
3195 | (propagated-inputs | |
3196 | `(("r-biocgenerics" ,r-biocgenerics) | |
3197 | ("r-biocparallel" ,r-biocparallel) | |
3198 | ("r-biostrings" ,r-biostrings) | |
3199 | ("r-bit64" ,r-bit64) | |
3200 | ("r-dplyr" ,r-dplyr) | |
3201 | ("r-ggplot2" ,r-ggplot2) | |
3202 | ("r-magrittr" ,r-magrittr) | |
3203 | ("r-rhdf5" ,r-rhdf5) | |
3204 | ("r-shortread" ,r-shortread) | |
3205 | ("r-stringr" ,r-stringr) | |
3206 | ("r-tibble" ,r-tibble) | |
3207 | ("r-tidyr" ,r-tidyr) | |
3208 | ("r-xvector" ,r-xvector))) | |
3209 | (home-page "https://bioconductor.org/packages/IONiseR/") | |
3210 | (synopsis "Quality assessment tools for Oxford Nanopore MinION data") | |
3211 | (description | |
3212 | "IONiseR provides tools for the quality assessment of Oxford Nanopore | |
3213 | MinION data. It extracts summary statistics from a set of fast5 files and can | |
3214 | be used either before or after base calling. In addition to standard | |
3215 | summaries of the read-types produced, it provides a number of plots for | |
3216 | visualising metrics relative to experiment run time or spatially over the | |
3217 | surface of a flowcell.") | |
3218 | (license license:expat))) | |
80eb01c7 RW |
3219 | |
3220 | ;; This is a CRAN package, but it depends on packages from Bioconductor. | |
3221 | (define-public r-gkmsvm | |
3222 | (package | |
3223 | (name "r-gkmsvm") | |
975cfe26 | 3224 | (version "0.80.0") |
80eb01c7 RW |
3225 | (source |
3226 | (origin | |
3227 | (method url-fetch) | |
3228 | (uri (cran-uri "gkmSVM" version)) | |
3229 | (sha256 | |
3230 | (base32 | |
975cfe26 | 3231 | "0ljcga246ad0ql8x3drvrdsyp0f20mgp3p6lnl79xb76qgfdnm0p")))) |
80eb01c7 RW |
3232 | (properties `((upstream-name . "gkmSVM"))) |
3233 | (build-system r-build-system) | |
3234 | (propagated-inputs | |
975cfe26 | 3235 | `(("r-kernlab" ,r-kernlab) |
80eb01c7 RW |
3236 | ("r-rcpp" ,r-rcpp) |
3237 | ("r-rocr" ,r-rocr) | |
80eb01c7 RW |
3238 | ("r-seqinr" ,r-seqinr))) |
3239 | (home-page "https://cran.r-project.org/web/packages/gkmSVM") | |
3240 | (synopsis "Gapped-kmer support vector machine") | |
3241 | (description | |
3242 | "This R package provides tools for training gapped-kmer SVM classifiers | |
3243 | for DNA and protein sequences. This package supports several sequence | |
3244 | kernels, including: gkmSVM, kmer-SVM, mismatch kernel and wildcard kernel.") | |
3245 | (license license:gpl2+))) | |
8a5460b4 | 3246 | |
f2114762 RW |
3247 | ;; This is a CRAN package, but it depends on multtest from Bioconductor. |
3248 | (define-public r-mutoss | |
3249 | (package | |
3250 | (name "r-mutoss") | |
3251 | (version "0.1-12") | |
3252 | (source | |
3253 | (origin | |
3254 | (method url-fetch) | |
3255 | (uri (cran-uri "mutoss" version)) | |
3256 | (sha256 | |
3257 | (base32 | |
3258 | "1yk7p7pb2xm38d3j19ysgwmix48lvimbhkhjjwk5jmr1a0ysx298")))) | |
3259 | (properties `((upstream-name . "mutoss"))) | |
3260 | (build-system r-build-system) | |
3261 | (propagated-inputs | |
3262 | `(("r-multcomp" ,r-multcomp) | |
3263 | ("r-multtest" ,r-multtest) | |
3264 | ("r-mvtnorm" ,r-mvtnorm) | |
3265 | ("r-plotrix" ,r-plotrix))) | |
3266 | (home-page "https://github.com/kornl/mutoss/") | |
3267 | (synopsis "Unified multiple testing procedures") | |
3268 | (description | |
3269 | "This package is designed to ease the application and comparison of | |
3270 | multiple hypothesis testing procedures for FWER, gFWER, FDR and FDX. Methods | |
3271 | are standardized and usable by the accompanying mutossGUI package.") | |
3272 | ;; Any version of the GPL. | |
3273 | (license (list license:gpl2+ license:gpl3+)))) | |
3274 | ||
bf770d92 RW |
3275 | ;; This is a CRAN package, but it depends on mutoss, which depends on multtest |
3276 | ;; from Bioconductor, so we put it here. | |
3277 | (define-public r-metap | |
3278 | (package | |
3279 | (name "r-metap") | |
fd6412cd | 3280 | (version "1.3") |
bf770d92 RW |
3281 | (source |
3282 | (origin | |
3283 | (method url-fetch) | |
3284 | (uri (cran-uri "metap" version)) | |
3285 | (sha256 | |
3286 | (base32 | |
fd6412cd | 3287 | "1jmmmmjiklaxfl604hwqil193ydaghvd5jv8xsr4bx3pzn5i9kvz")))) |
bf770d92 RW |
3288 | (build-system r-build-system) |
3289 | (propagated-inputs | |
3290 | `(("r-lattice" ,r-lattice) | |
3291 | ("r-mutoss" ,r-mutoss) | |
3292 | ("r-rdpack" ,r-rdpack) | |
3293 | ("r-tfisher" ,r-tfisher))) | |
3294 | (home-page "http://www.dewey.myzen.co.uk/meta/meta.html") | |
3295 | (synopsis "Meta-analysis of significance values") | |
3296 | (description | |
3297 | "The canonical way to perform meta-analysis involves using effect sizes. | |
3298 | When they are not available this package provides a number of methods for | |
3299 | meta-analysis of significance values including the methods of Edgington, | |
3300 | Fisher, Stouffer, Tippett, and Wilkinson; a number of data-sets to replicate | |
3301 | published results; and a routine for graphical display.") | |
3302 | (license license:gpl2))) | |
3303 | ||
8a5460b4 RW |
3304 | (define-public r-triform |
3305 | (package | |
3306 | (name "r-triform") | |
a18f325e | 3307 | (version "1.28.0") |
8a5460b4 RW |
3308 | (source |
3309 | (origin | |
3310 | (method url-fetch) | |
3311 | (uri (bioconductor-uri "triform" version)) | |
3312 | (sha256 | |
3313 | (base32 | |
a18f325e | 3314 | "12qdyrcw2mcawqdw65v0hjaghzlwa10xl6j8458izcrm5k6dlvz9")))) |
8a5460b4 RW |
3315 | (build-system r-build-system) |
3316 | (propagated-inputs | |
3317 | `(("r-biocgenerics" ,r-biocgenerics) | |
3318 | ("r-iranges" ,r-iranges) | |
3319 | ("r-yaml" ,r-yaml))) | |
3320 | (home-page "https://bioconductor.org/packages/triform/") | |
3321 | (synopsis "Find enriched regions in transcription factor ChIP-sequencing data") | |
3322 | (description | |
3323 | "The Triform algorithm uses model-free statistics to identify peak-like | |
3324 | distributions of TF ChIP sequencing reads, taking advantage of an improved | |
3325 | peak definition in combination with known profile characteristics.") | |
3326 | (license license:gpl2))) | |
c538bcdd RW |
3327 | |
3328 | (define-public r-varianttools | |
3329 | (package | |
3330 | (name "r-varianttools") | |
9b72bbf7 | 3331 | (version "1.28.0") |
c538bcdd RW |
3332 | (source |
3333 | (origin | |
3334 | (method url-fetch) | |
3335 | (uri (bioconductor-uri "VariantTools" version)) | |
3336 | (sha256 | |
3337 | (base32 | |
9b72bbf7 | 3338 | "0aafcprsqbn1xl8jqnxfl8r2d0lmzhssqpr26lam2cprh3yk0xiv")))) |
c538bcdd RW |
3339 | (properties `((upstream-name . "VariantTools"))) |
3340 | (build-system r-build-system) | |
3341 | (propagated-inputs | |
3342 | `(("r-biobase" ,r-biobase) | |
3343 | ("r-biocgenerics" ,r-biocgenerics) | |
3344 | ("r-biocparallel" ,r-biocparallel) | |
3345 | ("r-biostrings" ,r-biostrings) | |
3346 | ("r-bsgenome" ,r-bsgenome) | |
3347 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3348 | ("r-genomicfeatures" ,r-genomicfeatures) | |
3349 | ("r-genomicranges" ,r-genomicranges) | |
3350 | ("r-iranges" ,r-iranges) | |
3351 | ("r-matrix" ,r-matrix) | |
3352 | ("r-rsamtools" ,r-rsamtools) | |
3353 | ("r-rtracklayer" ,r-rtracklayer) | |
3354 | ("r-s4vectors" ,r-s4vectors) | |
3355 | ("r-variantannotation" ,r-variantannotation))) | |
3356 | (home-page "https://bioconductor.org/packages/VariantTools/") | |
3357 | (synopsis "Tools for exploratory analysis of variant calls") | |
3358 | (description | |
3359 | "Explore, diagnose, and compare variant calls using filters. The | |
3360 | VariantTools package supports a workflow for loading data, calling single | |
3361 | sample variants and tumor-specific somatic mutations or other sample-specific | |
3362 | variant types (e.g., RNA editing). Most of the functions operate on | |
3363 | alignments (BAM files) or datasets of called variants. The user is expected | |
3364 | to have already aligned the reads with a separate tool, e.g., GSNAP via | |
3365 | gmapR.") | |
3366 | (license license:artistic2.0))) | |
3e41919d RW |
3367 | |
3368 | (define-public r-heatplus | |
3369 | (package | |
3370 | (name "r-heatplus") | |
776e98fe | 3371 | (version "2.32.1") |
3e41919d RW |
3372 | (source |
3373 | (origin | |
3374 | (method url-fetch) | |
3375 | (uri (bioconductor-uri "Heatplus" version)) | |
3376 | (sha256 | |
3377 | (base32 | |
776e98fe | 3378 | "1ldxj2hasg6ysh70sc73mz2v4h3n8gf3lii09c3sqc4wmz5h7rp1")))) |
3e41919d RW |
3379 | (properties `((upstream-name . "Heatplus"))) |
3380 | (build-system r-build-system) | |
3381 | (propagated-inputs | |
3382 | `(("r-rcolorbrewer" ,r-rcolorbrewer))) | |
3383 | (home-page "https://github.com/alexploner/Heatplus") | |
3384 | (synopsis "Heatmaps with row and/or column covariates and colored clusters") | |
3385 | (description | |
3386 | "This package provides tools to display a rectangular heatmap (intensity | |
3387 | plot) of a data matrix. By default, both samples (columns) and features (row) | |
3388 | of the matrix are sorted according to a hierarchical clustering, and the | |
3389 | corresponding dendrogram is plotted. Optionally, panels with additional | |
3390 | information about samples and features can be added to the plot.") | |
3391 | (license license:gpl2+))) | |
c04f230e RW |
3392 | |
3393 | (define-public r-gosemsim | |
3394 | (package | |
3395 | (name "r-gosemsim") | |
d5951dc4 | 3396 | (version "2.12.1") |
c04f230e RW |
3397 | (source |
3398 | (origin | |
3399 | (method url-fetch) | |
3400 | (uri (bioconductor-uri "GOSemSim" version)) | |
3401 | (sha256 | |
3402 | (base32 | |
d5951dc4 | 3403 | "1r8yx6qw6d6602cp8aspzl3shi1l1zqcrc8fm9d5wg01sw1whs05")))) |
c04f230e RW |
3404 | (properties `((upstream-name . "GOSemSim"))) |
3405 | (build-system r-build-system) | |
3406 | (propagated-inputs | |
3407 | `(("r-annotationdbi" ,r-annotationdbi) | |
3408 | ("r-go-db" ,r-go-db) | |
3409 | ("r-rcpp" ,r-rcpp))) | |
d5951dc4 RW |
3410 | (native-inputs |
3411 | `(("r-knitr" ,r-knitr))) | |
c04f230e RW |
3412 | (home-page "https://guangchuangyu.github.io/software/GOSemSim") |
3413 | (synopsis "GO-terms semantic similarity measures") | |
3414 | (description | |
3415 | "The semantic comparisons of @dfn{Gene Ontology} (GO) annotations provide | |
3416 | quantitative ways to compute similarities between genes and gene groups, and | |
3417 | have became important basis for many bioinformatics analysis approaches. | |
3418 | GOSemSim is an R package for semantic similarity computation among GO terms, | |
3419 | sets of GO terms, gene products and gene clusters.") | |
3420 | (license license:artistic2.0))) | |
9d0f7942 RW |
3421 | |
3422 | (define-public r-anota | |
3423 | (package | |
3424 | (name "r-anota") | |
5ed76752 | 3425 | (version "1.34.0") |
9d0f7942 RW |
3426 | (source |
3427 | (origin | |
3428 | (method url-fetch) | |
3429 | (uri (bioconductor-uri "anota" version)) | |
3430 | (sha256 | |
3431 | (base32 | |
5ed76752 | 3432 | "1bkavzrxy1bjz0bwapwa9i3ysln7gljgziwd8c05fmg2f46j1z6m")))) |
9d0f7942 RW |
3433 | (build-system r-build-system) |
3434 | (propagated-inputs | |
3435 | `(("r-multtest" ,r-multtest) | |
3436 | ("r-qvalue" ,r-qvalue))) | |
3437 | (home-page "https://bioconductor.org/packages/anota/") | |
3438 | (synopsis "Analysis of translational activity") | |
3439 | (description | |
3440 | "Genome wide studies of translational control is emerging as a tool to | |
0cea26bd | 3441 | study various biological conditions. The output from such analysis is both |
9d0f7942 RW |
3442 | the mRNA level (e.g. cytosolic mRNA level) and the levl of mRNA actively |
3443 | involved in translation (the actively translating mRNA level) for each mRNA. | |
3444 | The standard analysis of such data strives towards identifying differential | |
3445 | translational between two or more sample classes - i.e. differences in | |
3446 | actively translated mRNA levels that are independent of underlying differences | |
3447 | in cytosolic mRNA levels. This package allows for such analysis using partial | |
3448 | variances and the random variance model. As 10s of thousands of mRNAs are | |
4f664004 | 3449 | analyzed in parallel the library performs a number of tests to assure that |
9d0f7942 RW |
3450 | the data set is suitable for such analysis.") |
3451 | (license license:gpl3))) | |
a6d867fe RW |
3452 | |
3453 | (define-public r-sigpathway | |
3454 | (package | |
3455 | (name "r-sigpathway") | |
869965df | 3456 | (version "1.54.0") |
a6d867fe RW |
3457 | (source |
3458 | (origin | |
3459 | (method url-fetch) | |
3460 | (uri (bioconductor-uri "sigPathway" version)) | |
3461 | (sha256 | |
3462 | (base32 | |
869965df | 3463 | "057qdkbfldpy6hsysk9mrs1vvsqgyl9yx2s6c2f26jz1pardkbqb")))) |
a6d867fe RW |
3464 | (properties `((upstream-name . "sigPathway"))) |
3465 | (build-system r-build-system) | |
3466 | (home-page "https://www.pnas.org/cgi/doi/10.1073/pnas.0506577102") | |
3467 | (synopsis "Pathway analysis") | |
3468 | (description | |
3469 | "This package is used to conduct pathway analysis by calculating the NT_k | |
3470 | and NE_k statistics in a statistical framework for determining whether a | |
3471 | specified group of genes for a pathway has a coordinated association with a | |
3472 | phenotype of interest.") | |
3473 | (license license:gpl2))) | |
af26c7ae RW |
3474 | |
3475 | (define-public r-fgsea | |
3476 | (package | |
3477 | (name "r-fgsea") | |
b4e1268c | 3478 | (version "1.12.0") |
af26c7ae RW |
3479 | (source |
3480 | (origin | |
3481 | (method url-fetch) | |
3482 | (uri (bioconductor-uri "fgsea" version)) | |
3483 | (sha256 | |
3484 | (base32 | |
b4e1268c | 3485 | "0pbq3g515kcbi4wvfx8m09p01h2f8vwsi1qqsyahxz4r1fasz4c1")))) |
af26c7ae RW |
3486 | (build-system r-build-system) |
3487 | (propagated-inputs | |
ebffd24c RW |
3488 | `(("r-bh" ,r-bh) |
3489 | ("r-biocparallel" ,r-biocparallel) | |
af26c7ae RW |
3490 | ("r-data-table" ,r-data-table) |
3491 | ("r-fastmatch" ,r-fastmatch) | |
3492 | ("r-ggplot2" ,r-ggplot2) | |
3493 | ("r-gridextra" ,r-gridextra) | |
3494 | ("r-matrix" ,r-matrix) | |
3495 | ("r-rcpp" ,r-rcpp))) | |
3496 | (home-page "https://github.com/ctlab/fgsea/") | |
3497 | (synopsis "Fast gene set enrichment analysis") | |
3498 | (description | |
3499 | "The package implements an algorithm for fast gene set enrichment | |
3500 | analysis. Using the fast algorithm allows to make more permutations and get | |
3501 | more fine grained p-values, which allows to use accurate stantard approaches | |
3502 | to multiple hypothesis correction.") | |
3503 | (license license:expat))) | |
305050b5 RW |
3504 | |
3505 | (define-public r-dose | |
3506 | (package | |
3507 | (name "r-dose") | |
166b3c2d | 3508 | (version "3.12.0") |
305050b5 RW |
3509 | (source |
3510 | (origin | |
3511 | (method url-fetch) | |
3512 | (uri (bioconductor-uri "DOSE" version)) | |
3513 | (sha256 | |
3514 | (base32 | |
166b3c2d | 3515 | "0ss8mr28q0vswxjmhcas0aqag5nl099jbyn5w3ypbbxqwfvf9jj5")))) |
305050b5 RW |
3516 | (properties `((upstream-name . "DOSE"))) |
3517 | (build-system r-build-system) | |
3518 | (propagated-inputs | |
3519 | `(("r-annotationdbi" ,r-annotationdbi) | |
3520 | ("r-biocparallel" ,r-biocparallel) | |
3521 | ("r-do-db" ,r-do-db) | |
3522 | ("r-fgsea" ,r-fgsea) | |
3523 | ("r-ggplot2" ,r-ggplot2) | |
3524 | ("r-gosemsim" ,r-gosemsim) | |
3525 | ("r-qvalue" ,r-qvalue) | |
3526 | ("r-reshape2" ,r-reshape2) | |
3527 | ("r-s4vectors" ,r-s4vectors))) | |
3528 | (home-page "https://guangchuangyu.github.io/software/DOSE/") | |
3529 | (synopsis "Disease ontology semantic and enrichment analysis") | |
3530 | (description | |
3531 | "This package implements five methods proposed by Resnik, Schlicker, | |
3532 | Jiang, Lin and Wang, respectively, for measuring semantic similarities among | |
3533 | @dfn{Disease ontology} (DO) terms and gene products. Enrichment analyses | |
3534 | including hypergeometric model and gene set enrichment analysis are also | |
3535 | implemented for discovering disease associations of high-throughput biological | |
3536 | data.") | |
3537 | (license license:artistic2.0))) | |
9c30cf65 RW |
3538 | |
3539 | (define-public r-enrichplot | |
3540 | (package | |
3541 | (name "r-enrichplot") | |
7621bf2d | 3542 | (version "1.6.1") |
9c30cf65 RW |
3543 | (source |
3544 | (origin | |
3545 | (method url-fetch) | |
3546 | (uri (bioconductor-uri "enrichplot" version)) | |
3547 | (sha256 | |
3548 | (base32 | |
7621bf2d | 3549 | "0707f5ll58psh7pr001cmmk5di7dprnbry1cy2mw20vn8p24nf3x")))) |
9c30cf65 RW |
3550 | (build-system r-build-system) |
3551 | (propagated-inputs | |
3552 | `(("r-annotationdbi" ,r-annotationdbi) | |
3553 | ("r-cowplot" ,r-cowplot) | |
3554 | ("r-dose" ,r-dose) | |
3555 | ("r-europepmc" ,r-europepmc) | |
3556 | ("r-ggplot2" ,r-ggplot2) | |
3557 | ("r-ggplotify" ,r-ggplotify) | |
3558 | ("r-ggraph" ,r-ggraph) | |
3559 | ("r-ggridges" ,r-ggridges) | |
3560 | ("r-gosemsim" ,r-gosemsim) | |
3561 | ("r-gridextra" ,r-gridextra) | |
3562 | ("r-igraph" ,r-igraph) | |
3563 | ("r-purrr" ,r-purrr) | |
3564 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
0654a9bc | 3565 | ("r-reshape2" ,r-reshape2))) |
9c30cf65 RW |
3566 | (home-page "https://github.com/GuangchuangYu/enrichplot") |
3567 | (synopsis "Visualization of functional enrichment result") | |
3568 | (description | |
3569 | "The enrichplot package implements several visualization methods for | |
3570 | interpreting functional enrichment results obtained from ORA or GSEA analyses. | |
3571 | All the visualization methods are developed based on ggplot2 graphics.") | |
3572 | (license license:artistic2.0))) | |
f8295ee6 RW |
3573 | |
3574 | (define-public r-clusterprofiler | |
3575 | (package | |
3576 | (name "r-clusterprofiler") | |
ac9a9c37 | 3577 | (version "3.14.3") |
f8295ee6 RW |
3578 | (source |
3579 | (origin | |
3580 | (method url-fetch) | |
3581 | (uri (bioconductor-uri "clusterProfiler" version)) | |
3582 | (sha256 | |
3583 | (base32 | |
ac9a9c37 | 3584 | "08pd7bmqmyxncj09ilz8yb9sf1pv9ni98y8b93pz2giy7pl407hg")))) |
f8295ee6 RW |
3585 | (properties |
3586 | `((upstream-name . "clusterProfiler"))) | |
3587 | (build-system r-build-system) | |
3588 | (propagated-inputs | |
3589 | `(("r-annotationdbi" ,r-annotationdbi) | |
3590 | ("r-dose" ,r-dose) | |
3591 | ("r-enrichplot" ,r-enrichplot) | |
3592 | ("r-ggplot2" ,r-ggplot2) | |
3593 | ("r-go-db" ,r-go-db) | |
3594 | ("r-gosemsim" ,r-gosemsim) | |
3595 | ("r-magrittr" ,r-magrittr) | |
3596 | ("r-plyr" ,r-plyr) | |
3597 | ("r-qvalue" ,r-qvalue) | |
3598 | ("r-rvcheck" ,r-rvcheck) | |
3599 | ("r-tidyr" ,r-tidyr))) | |
3600 | (home-page "https://guangchuangyu.github.io/software/clusterProfiler/") | |
3601 | (synopsis "Analysis and visualization of functional profiles for gene clusters") | |
3602 | (description | |
3603 | "This package implements methods to analyze and visualize functional | |
3604 | profiles (GO and KEGG) of gene and gene clusters.") | |
3605 | (license license:artistic2.0))) | |
ce77562a RW |
3606 | |
3607 | (define-public r-mlinterfaces | |
3608 | (package | |
3609 | (name "r-mlinterfaces") | |
e0061f51 | 3610 | (version "1.66.5") |
ce77562a RW |
3611 | (source |
3612 | (origin | |
3613 | (method url-fetch) | |
3614 | (uri (bioconductor-uri "MLInterfaces" version)) | |
3615 | (sha256 | |
3616 | (base32 | |
e0061f51 | 3617 | "05bg7qcrv485m03rkyq3qg5hrr1m3y7zx49bipwaivzqm3s1mbw5")))) |
ce77562a RW |
3618 | (properties `((upstream-name . "MLInterfaces"))) |
3619 | (build-system r-build-system) | |
3620 | (propagated-inputs | |
3621 | `(("r-annotate" ,r-annotate) | |
3622 | ("r-biobase" ,r-biobase) | |
3623 | ("r-biocgenerics" ,r-biocgenerics) | |
3624 | ("r-cluster" ,r-cluster) | |
3625 | ("r-fpc" ,r-fpc) | |
3626 | ("r-gbm" ,r-gbm) | |
3627 | ("r-gdata" ,r-gdata) | |
3628 | ("r-genefilter" ,r-genefilter) | |
3629 | ("r-ggvis" ,r-ggvis) | |
3630 | ("r-hwriter" ,r-hwriter) | |
3631 | ("r-mass" ,r-mass) | |
3632 | ("r-mlbench" ,r-mlbench) | |
3633 | ("r-pls" ,r-pls) | |
3634 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
ce77562a RW |
3635 | ("r-rpart" ,r-rpart) |
3636 | ("r-sfsmisc" ,r-sfsmisc) | |
3637 | ("r-shiny" ,r-shiny) | |
3638 | ("r-threejs" ,r-threejs))) | |
3639 | (home-page "https://bioconductor.org/packages/MLInterfaces/") | |
3640 | (synopsis "Interfaces to R machine learning procedures") | |
3641 | (description | |
3642 | "This package provides uniform interfaces to machine learning code for | |
3643 | data in R and Bioconductor containers.") | |
3644 | ;; Any version of the LGPL. | |
3645 | (license license:lgpl2.1+))) | |
a793e88c RW |
3646 | |
3647 | (define-public r-annaffy | |
3648 | (package | |
3649 | (name "r-annaffy") | |
fc4a9dd5 | 3650 | (version "1.58.0") |
a793e88c RW |
3651 | (source |
3652 | (origin | |
3653 | (method url-fetch) | |
3654 | (uri (bioconductor-uri "annaffy" version)) | |
3655 | (sha256 | |
3656 | (base32 | |
fc4a9dd5 | 3657 | "1jrf4bq2wky4ay1jrcy60si6hxdcn4j05w5vgs38yfb92gq77i16")))) |
a793e88c RW |
3658 | (build-system r-build-system) |
3659 | (arguments | |
3660 | `(#:phases | |
3661 | (modify-phases %standard-phases | |
3662 | (add-after 'unpack 'remove-reference-to-non-free-data | |
3663 | (lambda _ | |
3664 | (substitute* "DESCRIPTION" | |
3665 | ((", KEGG.db") "")) | |
3666 | #t))))) | |
3667 | (propagated-inputs | |
3668 | `(("r-annotationdbi" ,r-annotationdbi) | |
3669 | ("r-biobase" ,r-biobase) | |
3670 | ("r-dbi" ,r-dbi) | |
3671 | ("r-go-db" ,r-go-db))) | |
3672 | (home-page "https://bioconductor.org/packages/annaffy/") | |
3673 | (synopsis "Annotation tools for Affymetrix biological metadata") | |
3674 | (description | |
3675 | "This package provides functions for handling data from Bioconductor | |
3676 | Affymetrix annotation data packages. It produces compact HTML and text | |
3677 | reports including experimental data and URL links to many online databases. | |
3678 | It allows searching of biological metadata using various criteria.") | |
3679 | ;; Any version of the LGPL according to the DESCRIPTION file. A copy of | |
3680 | ;; the LGPL 2.1 is included. | |
3681 | (license license:lgpl2.1+))) | |
0ec0a5ec RW |
3682 | |
3683 | (define-public r-a4core | |
3684 | (package | |
3685 | (name "r-a4core") | |
4ed18ddc | 3686 | (version "1.34.0") |
0ec0a5ec RW |
3687 | (source |
3688 | (origin | |
3689 | (method url-fetch) | |
3690 | (uri (bioconductor-uri "a4Core" version)) | |
3691 | (sha256 | |
3692 | (base32 | |
4ed18ddc | 3693 | "0xcs9wl2yrprl4yc0z5s4zrkil3752k9xc1fi8fcx7zab1mm80df")))) |
0ec0a5ec RW |
3694 | (properties `((upstream-name . "a4Core"))) |
3695 | (build-system r-build-system) | |
3696 | (propagated-inputs | |
3697 | `(("r-biobase" ,r-biobase) | |
3698 | ("r-glmnet" ,r-glmnet))) | |
3699 | (home-page "https://bioconductor.org/packages/a4Core") | |
3700 | (synopsis "Automated Affymetrix array analysis core package") | |
3701 | (description | |
3702 | "This is the core package for the automated analysis of Affymetrix | |
3703 | arrays.") | |
3704 | (license license:gpl3))) | |
9ae37581 RW |
3705 | |
3706 | (define-public r-a4classif | |
3707 | (package | |
3708 | (name "r-a4classif") | |
102b982c | 3709 | (version "1.34.0") |
9ae37581 RW |
3710 | (source |
3711 | (origin | |
3712 | (method url-fetch) | |
3713 | (uri (bioconductor-uri "a4Classif" version)) | |
3714 | (sha256 | |
3715 | (base32 | |
102b982c | 3716 | "0gj3hdflfs1ybc2kshl9w1dzy0rfzppfj08hx3wa2chjsm0m9brn")))) |
9ae37581 RW |
3717 | (properties `((upstream-name . "a4Classif"))) |
3718 | (build-system r-build-system) | |
3719 | (propagated-inputs | |
3720 | `(("r-a4core" ,r-a4core) | |
3721 | ("r-a4preproc" ,r-a4preproc) | |
3722 | ("r-glmnet" ,r-glmnet) | |
3723 | ("r-mlinterfaces" ,r-mlinterfaces) | |
3724 | ("r-pamr" ,r-pamr) | |
3725 | ("r-rocr" ,r-rocr) | |
3726 | ("r-varselrf" ,r-varselrf))) | |
3727 | (home-page "https://bioconductor.org/packages/a4Classif/") | |
3728 | (synopsis "Automated Affymetrix array analysis classification package") | |
3729 | (description | |
3730 | "This is the classification package for the automated analysis of | |
3731 | Affymetrix arrays.") | |
3732 | (license license:gpl3))) | |
b8d13e2c RW |
3733 | |
3734 | (define-public r-a4preproc | |
3735 | (package | |
3736 | (name "r-a4preproc") | |
d6859c7c | 3737 | (version "1.34.0") |
b8d13e2c RW |
3738 | (source |
3739 | (origin | |
3740 | (method url-fetch) | |
3741 | (uri (bioconductor-uri "a4Preproc" version)) | |
3742 | (sha256 | |
3743 | (base32 | |
d6859c7c | 3744 | "11j5nc33gd6yis1fyagr0y39g21bzkc59kq8b8sd6b3pfc84zrjd")))) |
b8d13e2c RW |
3745 | (properties `((upstream-name . "a4Preproc"))) |
3746 | (build-system r-build-system) | |
3747 | (propagated-inputs | |
3748 | `(("r-annotationdbi" ,r-annotationdbi))) | |
3749 | (home-page "https://bioconductor.org/packages/a4Preproc/") | |
3750 | (synopsis "Automated Affymetrix array analysis preprocessing package") | |
3751 | (description | |
3752 | "This is a package for the automated analysis of Affymetrix arrays. It | |
3753 | is used for preprocessing the arrays.") | |
3754 | (license license:gpl3))) | |
8e15f861 RW |
3755 | |
3756 | (define-public r-a4reporting | |
3757 | (package | |
3758 | (name "r-a4reporting") | |
977a7802 | 3759 | (version "1.34.0") |
8e15f861 RW |
3760 | (source |
3761 | (origin | |
3762 | (method url-fetch) | |
3763 | (uri (bioconductor-uri "a4Reporting" version)) | |
3764 | (sha256 | |
3765 | (base32 | |
977a7802 | 3766 | "15nd4pa5hkdzkhinvqw5ijdqb7k5gk37v2hmk3jsg2d6m0jqphi5")))) |
8e15f861 RW |
3767 | (properties `((upstream-name . "a4Reporting"))) |
3768 | (build-system r-build-system) | |
3769 | (propagated-inputs | |
3770 | `(("r-annaffy" ,r-annaffy) | |
3771 | ("r-xtable" ,r-xtable))) | |
3772 | (home-page "https://bioconductor.org/packages/a4Reporting/") | |
3773 | (synopsis "Automated Affymetrix array analysis reporting package") | |
3774 | (description | |
3775 | "This is a package for the automated analysis of Affymetrix arrays. It | |
3776 | provides reporting features.") | |
3777 | (license license:gpl3))) | |
dbfe3375 RW |
3778 | |
3779 | (define-public r-a4base | |
3780 | (package | |
3781 | (name "r-a4base") | |
85c945aa | 3782 | (version "1.34.0") |
dbfe3375 RW |
3783 | (source |
3784 | (origin | |
3785 | (method url-fetch) | |
3786 | (uri (bioconductor-uri "a4Base" version)) | |
3787 | (sha256 | |
3788 | (base32 | |
85c945aa | 3789 | "0dgqyq4dnlcik5qqygnhxlhfr98sh6kmdcj2qllhrwyk0lmsfk01")))) |
dbfe3375 RW |
3790 | (properties `((upstream-name . "a4Base"))) |
3791 | (build-system r-build-system) | |
3792 | (propagated-inputs | |
3793 | `(("r-a4core" ,r-a4core) | |
3794 | ("r-a4preproc" ,r-a4preproc) | |
3795 | ("r-annaffy" ,r-annaffy) | |
3796 | ("r-annotationdbi" ,r-annotationdbi) | |
3797 | ("r-biobase" ,r-biobase) | |
3798 | ("r-genefilter" ,r-genefilter) | |
3799 | ("r-glmnet" ,r-glmnet) | |
3800 | ("r-gplots" ,r-gplots) | |
3801 | ("r-limma" ,r-limma) | |
3802 | ("r-mpm" ,r-mpm) | |
3803 | ("r-multtest" ,r-multtest))) | |
3804 | (home-page "https://bioconductor.org/packages/a4Base/") | |
3805 | (synopsis "Automated Affymetrix array analysis base package") | |
3806 | (description | |
3807 | "This package provides basic features for the automated analysis of | |
3808 | Affymetrix arrays.") | |
3809 | (license license:gpl3))) | |
84ad024e RW |
3810 | |
3811 | (define-public r-a4 | |
3812 | (package | |
3813 | (name "r-a4") | |
344eb4c4 | 3814 | (version "1.34.0") |
84ad024e RW |
3815 | (source |
3816 | (origin | |
3817 | (method url-fetch) | |
3818 | (uri (bioconductor-uri "a4" version)) | |
3819 | (sha256 | |
3820 | (base32 | |
344eb4c4 | 3821 | "14yipy6s2wqr9q0yp09x1mm17npknrhs6yd34i3wrb5id64ywnq4")))) |
84ad024e RW |
3822 | (build-system r-build-system) |
3823 | (propagated-inputs | |
3824 | `(("r-a4base" ,r-a4base) | |
3825 | ("r-a4classif" ,r-a4classif) | |
3826 | ("r-a4core" ,r-a4core) | |
3827 | ("r-a4preproc" ,r-a4preproc) | |
3828 | ("r-a4reporting" ,r-a4reporting))) | |
3829 | (home-page "https://bioconductor.org/packages/a4/") | |
3830 | (synopsis "Automated Affymetrix array analysis umbrella package") | |
3831 | (description | |
3832 | "This package provides a software suite for the automated analysis of | |
3833 | Affymetrix arrays.") | |
3834 | (license license:gpl3))) | |
59d331f1 RW |
3835 | |
3836 | (define-public r-abseqr | |
3837 | (package | |
3838 | (name "r-abseqr") | |
aef4b346 | 3839 | (version "1.4.0") |
59d331f1 RW |
3840 | (source |
3841 | (origin | |
3842 | (method url-fetch) | |
3843 | (uri (bioconductor-uri "abseqR" version)) | |
3844 | (sha256 | |
3845 | (base32 | |
aef4b346 | 3846 | "1n9h5qkj4njr1f8fvhg9sj9wxcd7hljnnk8m80zwswzs2n9ivppa")))) |
59d331f1 RW |
3847 | (properties `((upstream-name . "abseqR"))) |
3848 | (build-system r-build-system) | |
3849 | (inputs | |
3850 | `(("pandoc" ,ghc-pandoc))) | |
3851 | (propagated-inputs | |
3852 | `(("r-biocparallel" ,r-biocparallel) | |
3853 | ("r-biocstyle" ,r-biocstyle) | |
3854 | ("r-circlize" ,r-circlize) | |
3855 | ("r-flexdashboard" ,r-flexdashboard) | |
3856 | ("r-ggcorrplot" ,r-ggcorrplot) | |
3857 | ("r-ggdendro" ,r-ggdendro) | |
3858 | ("r-ggplot2" ,r-ggplot2) | |
3859 | ("r-gridextra" ,r-gridextra) | |
3860 | ("r-knitr" ,r-knitr) | |
3861 | ("r-plotly" ,r-plotly) | |
3862 | ("r-plyr" ,r-plyr) | |
3863 | ("r-png" ,r-png) | |
3864 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
3865 | ("r-reshape2" ,r-reshape2) | |
3866 | ("r-rmarkdown" ,r-rmarkdown) | |
3867 | ("r-stringr" ,r-stringr) | |
3868 | ("r-vegan" ,r-vegan) | |
3869 | ("r-venndiagram" ,r-venndiagram))) | |
3870 | (home-page "https://github.com/malhamdoosh/abseqR") | |
3871 | (synopsis "Reporting and data analysis for Rep-Seq datasets of antibody libraries") | |
3872 | (description | |
3873 | "AbSeq is a comprehensive bioinformatic pipeline for the analysis of | |
3874 | sequencing datasets generated from antibody libraries and abseqR is one of its | |
3875 | packages. AbseqR empowers the users of abseqPy with plotting and reporting | |
3876 | capabilities and allows them to generate interactive HTML reports for the | |
3877 | convenience of viewing and sharing with other researchers. Additionally, | |
3878 | abseqR extends abseqPy to compare multiple repertoire analyses and perform | |
3879 | further downstream analysis on its output.") | |
3880 | (license license:gpl3))) | |
41aab7d1 RW |
3881 | |
3882 | (define-public r-bacon | |
3883 | (package | |
3884 | (name "r-bacon") | |
32b471f4 | 3885 | (version "1.14.0") |
41aab7d1 RW |
3886 | (source |
3887 | (origin | |
3888 | (method url-fetch) | |
3889 | (uri (bioconductor-uri "bacon" version)) | |
3890 | (sha256 | |
3891 | (base32 | |
32b471f4 | 3892 | "1q18vm4znl47v56cnvx9y5ygrial2mdjpl8x1043jq00kyygrc86")))) |
41aab7d1 RW |
3893 | (build-system r-build-system) |
3894 | (propagated-inputs | |
3895 | `(("r-biocparallel" ,r-biocparallel) | |
3896 | ("r-ellipse" ,r-ellipse) | |
3897 | ("r-ggplot2" ,r-ggplot2))) | |
3898 | (home-page "https://bioconductor.org/packages/bacon/") | |
3899 | (synopsis "Controlling bias and inflation in association studies") | |
3900 | (description | |
3901 | "Bacon can be used to remove inflation and bias often observed in | |
3902 | epigenome- and transcriptome-wide association studies. To this end bacon | |
3903 | constructs an empirical null distribution using a Gibbs Sampling algorithm by | |
3904 | fitting a three-component normal mixture on z-scores.") | |
3905 | (license license:gpl2+))) | |
051e8e1a RW |
3906 | |
3907 | (define-public r-rgadem | |
3908 | (package | |
3909 | (name "r-rgadem") | |
07189489 | 3910 | (version "2.34.1") |
051e8e1a RW |
3911 | (source |
3912 | (origin | |
3913 | (method url-fetch) | |
3914 | (uri (bioconductor-uri "rGADEM" version)) | |
3915 | (sha256 | |
3916 | (base32 | |
07189489 | 3917 | "12xm4p4qsczf57kip8bvi6pr8sb5gvn11dnbz7lbh6sc03sx3q2h")))) |
051e8e1a RW |
3918 | (properties `((upstream-name . "rGADEM"))) |
3919 | (build-system r-build-system) | |
3920 | (propagated-inputs | |
3921 | `(("r-biostrings" ,r-biostrings) | |
3922 | ("r-bsgenome" ,r-bsgenome) | |
07189489 | 3923 | ("r-genomicranges" ,r-genomicranges) |
051e8e1a RW |
3924 | ("r-iranges" ,r-iranges) |
3925 | ("r-seqlogo" ,r-seqlogo))) | |
3926 | (home-page "https://bioconductor.org/packages/rGADEM/") | |
3927 | (synopsis "De novo sequence motif discovery") | |
3928 | (description | |
3929 | "rGADEM is an efficient de novo motif discovery tool for large-scale | |
3930 | genomic sequence data.") | |
3931 | (license license:artistic2.0))) | |
229f97c3 RW |
3932 | |
3933 | (define-public r-motiv | |
3934 | (package | |
3935 | (name "r-motiv") | |
35a1b3ec | 3936 | (version "1.42.0") |
229f97c3 RW |
3937 | (source |
3938 | (origin | |
3939 | (method url-fetch) | |
3940 | (uri (bioconductor-uri "MotIV" version)) | |
3941 | (sha256 | |
3942 | (base32 | |
35a1b3ec | 3943 | "07k4rw4nhcn4sg43psv1h7qr064gws22m2yyr7x8sy3f1i1c954k")))) |
229f97c3 RW |
3944 | (properties `((upstream-name . "MotIV"))) |
3945 | (build-system r-build-system) | |
3946 | (inputs | |
3947 | `(("gsl" ,gsl))) | |
3948 | (propagated-inputs | |
3949 | `(("r-biocgenerics" ,r-biocgenerics) | |
3950 | ("r-biostrings" ,r-biostrings) | |
35a1b3ec | 3951 | ("r-genomicranges" ,r-genomicranges) |
229f97c3 RW |
3952 | ("r-iranges" ,r-iranges) |
3953 | ("r-lattice" ,r-lattice) | |
3954 | ("r-rgadem" ,r-rgadem) | |
3955 | ("r-s4vectors" ,r-s4vectors))) | |
3956 | (home-page "https://bioconductor.org/packages/MotIV/") | |
3957 | (synopsis "Motif identification and validation") | |
3958 | (description | |
3959 | "This package is used for the identification and validation of sequence | |
3960 | motifs. It makes use of STAMP for comparing a set of motifs to a given | |
3961 | database (e.g. JASPAR). It can also be used to visualize motifs, motif | |
3962 | distributions, modules and filter motifs.") | |
3963 | (license license:gpl2))) | |
2a72ef56 RW |
3964 | |
3965 | (define-public r-motifstack | |
3966 | (package | |
3967 | (name "r-motifstack") | |
dda936ca | 3968 | (version "1.30.0") |
2a72ef56 RW |
3969 | (source |
3970 | (origin | |
3971 | (method url-fetch) | |
3972 | (uri (bioconductor-uri "motifStack" version)) | |
3973 | (sha256 | |
3974 | (base32 | |
dda936ca | 3975 | "00rafqs1gqlcxlbsdn9qnq9xb7wjphiksb3hsx76viqjbjzi14wg")))) |
2a72ef56 RW |
3976 | (properties `((upstream-name . "motifStack"))) |
3977 | (build-system r-build-system) | |
3978 | (propagated-inputs | |
3979 | `(("r-ade4" ,r-ade4) | |
3980 | ("r-biostrings" ,r-biostrings) | |
dda936ca | 3981 | ("r-ggplot2" ,r-ggplot2) |
aa0ebfd2 | 3982 | ("r-grimport2" ,r-grimport2) |
2a72ef56 RW |
3983 | ("r-htmlwidgets" ,r-htmlwidgets) |
3984 | ("r-motiv" ,r-motiv) | |
3985 | ("r-scales" ,r-scales) | |
3986 | ("r-xml" ,r-xml))) | |
3987 | (home-page "https://bioconductor.org/packages/motifStack/") | |
3988 | (synopsis "Plot stacked logos for DNA, RNA and amino acid sequences") | |
3989 | (description | |
3990 | "The motifStack package is designed for graphic representation of | |
3991 | multiple motifs with different similarity scores. It works with both DNA/RNA | |
3992 | sequence motifs and amino acid sequence motifs. In addition, it provides the | |
3993 | flexibility for users to customize the graphic parameters such as the font | |
3994 | type and symbol colors.") | |
3995 | (license license:gpl2+))) | |
e5bff307 RW |
3996 | |
3997 | (define-public r-genomicscores | |
3998 | (package | |
3999 | (name "r-genomicscores") | |
e89f16e6 | 4000 | (version "1.10.0") |
e5bff307 RW |
4001 | (source |
4002 | (origin | |
4003 | (method url-fetch) | |
4004 | (uri (bioconductor-uri "GenomicScores" version)) | |
4005 | (sha256 | |
4006 | (base32 | |
e89f16e6 | 4007 | "175iaqv7npa11yw48vmqpgx0qqs3g44c3dsya7ccwd1lg97fznkj")))) |
e5bff307 RW |
4008 | (properties `((upstream-name . "GenomicScores"))) |
4009 | (build-system r-build-system) | |
4010 | (propagated-inputs | |
4011 | `(("r-annotationhub" ,r-annotationhub) | |
4012 | ("r-biobase" ,r-biobase) | |
4013 | ("r-biocgenerics" ,r-biocgenerics) | |
4014 | ("r-biostrings" ,r-biostrings) | |
4015 | ("r-bsgenome" ,r-bsgenome) | |
4016 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4017 | ("r-genomicranges" ,r-genomicranges) | |
4018 | ("r-iranges" ,r-iranges) | |
4019 | ("r-s4vectors" ,r-s4vectors) | |
4020 | ("r-xml" ,r-xml))) | |
4021 | (home-page "https://github.com/rcastelo/GenomicScores/") | |
4022 | (synopsis "Work with genome-wide position-specific scores") | |
4023 | (description | |
4024 | "This package provides infrastructure to store and access genome-wide | |
4025 | position-specific scores within R and Bioconductor.") | |
4026 | (license license:artistic2.0))) | |
32e0f906 RW |
4027 | |
4028 | (define-public r-atacseqqc | |
4029 | (package | |
4030 | (name "r-atacseqqc") | |
dc30cc03 | 4031 | (version "1.10.3") |
32e0f906 RW |
4032 | (source |
4033 | (origin | |
4034 | (method url-fetch) | |
4035 | (uri (bioconductor-uri "ATACseqQC" version)) | |
4036 | (sha256 | |
4037 | (base32 | |
dc30cc03 | 4038 | "18zf90iksglbs13cwr4jjwsv332a19lf4bpdmy69jz8bpwrklv22")))) |
32e0f906 RW |
4039 | (properties `((upstream-name . "ATACseqQC"))) |
4040 | (build-system r-build-system) | |
4041 | (propagated-inputs | |
4042 | `(("r-biocgenerics" ,r-biocgenerics) | |
4043 | ("r-biostrings" ,r-biostrings) | |
4044 | ("r-bsgenome" ,r-bsgenome) | |
4045 | ("r-chippeakanno" ,r-chippeakanno) | |
bcc233c1 | 4046 | ("r-edger" ,r-edger) |
32e0f906 RW |
4047 | ("r-genomeinfodb" ,r-genomeinfodb) |
4048 | ("r-genomicalignments" ,r-genomicalignments) | |
4049 | ("r-genomicranges" ,r-genomicranges) | |
4050 | ("r-genomicscores" ,r-genomicscores) | |
4051 | ("r-iranges" ,r-iranges) | |
4052 | ("r-kernsmooth" ,r-kernsmooth) | |
4053 | ("r-limma" ,r-limma) | |
4054 | ("r-motifstack" ,r-motifstack) | |
4055 | ("r-preseqr" ,r-preseqr) | |
4056 | ("r-randomforest" ,r-randomforest) | |
4057 | ("r-rsamtools" ,r-rsamtools) | |
4058 | ("r-rtracklayer" ,r-rtracklayer) | |
4059 | ("r-s4vectors" ,r-s4vectors))) | |
dc30cc03 RW |
4060 | (native-inputs |
4061 | `(("r-knitr" ,r-knitr))) | |
32e0f906 RW |
4062 | (home-page "https://bioconductor.org/packages/ATACseqQC/") |
4063 | (synopsis "ATAC-seq quality control") | |
4064 | (description | |
4065 | "ATAC-seq, an assay for Transposase-Accessible Chromatin using | |
4066 | sequencing, is a rapid and sensitive method for chromatin accessibility | |
4067 | analysis. It was developed as an alternative method to MNase-seq, FAIRE-seq | |
4068 | and DNAse-seq. The ATACseqQC package was developed to help users to quickly | |
4069 | assess whether their ATAC-seq experiment is successful. It includes | |
4070 | diagnostic plots of fragment size distribution, proportion of mitochondria | |
4071 | reads, nucleosome positioning pattern, and CTCF or other Transcript Factor | |
4072 | footprints.") | |
4073 | (license license:gpl2+))) | |
3972cfce RW |
4074 | |
4075 | (define-public r-gofuncr | |
4076 | (package | |
4077 | (name "r-gofuncr") | |
4997e025 | 4078 | (version "1.6.0") |
3972cfce RW |
4079 | (source |
4080 | (origin | |
4081 | (method url-fetch) | |
4082 | (uri (bioconductor-uri "GOfuncR" version)) | |
4083 | (sha256 | |
4084 | (base32 | |
4997e025 | 4085 | "0hmi13pz923fm95asys615rih63b1i2nvynfczr1zcsc9fzn4h35")))) |
3972cfce RW |
4086 | (properties `((upstream-name . "GOfuncR"))) |
4087 | (build-system r-build-system) | |
4088 | (propagated-inputs | |
4089 | `(("r-annotationdbi" ,r-annotationdbi) | |
4090 | ("r-genomicranges" ,r-genomicranges) | |
4091 | ("r-gtools" ,r-gtools) | |
4092 | ("r-iranges" ,r-iranges) | |
4093 | ("r-mapplots" ,r-mapplots) | |
4094 | ("r-rcpp" ,r-rcpp) | |
4095 | ("r-vioplot" ,r-vioplot))) | |
4096 | (home-page "https://bioconductor.org/packages/GOfuncR/") | |
4097 | (synopsis "Gene ontology enrichment using FUNC") | |
4098 | (description | |
4099 | "GOfuncR performs a gene ontology enrichment analysis based on the | |
4100 | ontology enrichment software FUNC. GO-annotations are obtained from | |
4101 | OrganismDb or OrgDb packages (@code{Homo.sapiens} by default); the GO-graph is | |
4102 | included in the package and updated regularly. GOfuncR provides the standard | |
4103 | candidate vs background enrichment analysis using the hypergeometric test, as | |
4104 | well as three additional tests: | |
4105 | ||
4106 | @enumerate | |
4107 | @item the Wilcoxon rank-sum test that is used when genes are ranked, | |
4108 | @item a binomial test that is used when genes are associated with two counts, | |
4109 | and | |
4110 | @item a Chi-square or Fisher's exact test that is used in cases when genes are | |
4111 | associated with four counts. | |
4112 | @end enumerate | |
4113 | ||
4114 | To correct for multiple testing and interdependency of the tests, family-wise | |
4115 | error rates are computed based on random permutations of the gene-associated | |
4116 | variables. GOfuncR also provides tools for exploring the ontology graph and | |
4117 | the annotations, and options to take gene-length or spatial clustering of | |
4118 | genes into account. It is also possible to provide custom gene coordinates, | |
4119 | annotations and ontologies.") | |
4120 | (license license:gpl2+))) | |
9bf4bb19 RW |
4121 | |
4122 | (define-public r-abaenrichment | |
4123 | (package | |
4124 | (name "r-abaenrichment") | |
307667c4 | 4125 | (version "1.16.0") |
9bf4bb19 RW |
4126 | (source |
4127 | (origin | |
4128 | (method url-fetch) | |
4129 | (uri (bioconductor-uri "ABAEnrichment" version)) | |
4130 | (sha256 | |
4131 | (base32 | |
307667c4 | 4132 | "128ik28j8kmdkycffhxajv5h174zdq9sfn2gz6ai90wgkdadbzwp")))) |
9bf4bb19 RW |
4133 | (properties `((upstream-name . "ABAEnrichment"))) |
4134 | (build-system r-build-system) | |
4135 | (propagated-inputs | |
4136 | `(("r-abadata" ,r-abadata) | |
4137 | ("r-data-table" ,r-data-table) | |
4138 | ("r-gofuncr" ,r-gofuncr) | |
4139 | ("r-gplots" ,r-gplots) | |
4140 | ("r-gtools" ,r-gtools) | |
4141 | ("r-rcpp" ,r-rcpp))) | |
4142 | (home-page "https://bioconductor.org/packages/ABAEnrichment/") | |
4143 | (synopsis "Gene expression enrichment in human brain regions") | |
4144 | (description | |
4145 | "The package ABAEnrichment is designed to test for enrichment of user | |
4146 | defined candidate genes in the set of expressed genes in different human brain | |
4147 | regions. The core function @code{aba_enrich} integrates the expression of the | |
4148 | candidate gene set (averaged across donors) and the structural information of | |
4149 | the brain using an ontology, both provided by the Allen Brain Atlas project.") | |
4150 | (license license:gpl2+))) | |
0b91b7b9 RW |
4151 | |
4152 | (define-public r-annotationfuncs | |
4153 | (package | |
4154 | (name "r-annotationfuncs") | |
3a731c83 | 4155 | (version "1.36.0") |
0b91b7b9 RW |
4156 | (source |
4157 | (origin | |
4158 | (method url-fetch) | |
4159 | (uri (bioconductor-uri "AnnotationFuncs" version)) | |
4160 | (sha256 | |
4161 | (base32 | |
3a731c83 | 4162 | "0ws14b1ibqml7w8kj0gi7wdp6wd8dcdpnrmcxldjzsyawf17q0yq")))) |
0b91b7b9 RW |
4163 | (properties |
4164 | `((upstream-name . "AnnotationFuncs"))) | |
4165 | (build-system r-build-system) | |
4166 | (propagated-inputs | |
4167 | `(("r-annotationdbi" ,r-annotationdbi) | |
4168 | ("r-dbi" ,r-dbi))) | |
4169 | (home-page "https://www.iysik.com/r/annotationfuncs") | |
4170 | (synopsis "Annotation translation functions") | |
4171 | (description | |
4172 | "This package provides functions for handling translating between | |
4173 | different identifieres using the Biocore Data Team data-packages (e.g. | |
4174 | @code{org.Bt.eg.db}).") | |
4175 | (license license:gpl2))) | |
adf7d813 RW |
4176 | |
4177 | (define-public r-annotationtools | |
4178 | (package | |
4179 | (name "r-annotationtools") | |
eda49085 | 4180 | (version "1.60.0") |
adf7d813 RW |
4181 | (source |
4182 | (origin | |
4183 | (method url-fetch) | |
4184 | (uri (bioconductor-uri "annotationTools" version)) | |
4185 | (sha256 | |
4186 | (base32 | |
eda49085 | 4187 | "1cq7ayq2swp2ahlphz74nh5mb869rgyyr0kkqy1mxyilk8k2g44i")))) |
adf7d813 RW |
4188 | (properties |
4189 | `((upstream-name . "annotationTools"))) | |
4190 | (build-system r-build-system) | |
4191 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
4192 | (home-page "https://bioconductor.org/packages/annotationTools/") | |
4193 | (synopsis "Annotate microarrays and perform gene expression analyses") | |
4194 | (description | |
4195 | "This package provides functions to annotate microarrays, find orthologs, | |
4196 | and integrate heterogeneous gene expression profiles using annotation and | |
4197 | other molecular biology information available as flat file database (plain | |
4198 | text files).") | |
4199 | ;; Any version of the GPL. | |
4200 | (license (list license:gpl2+)))) | |
f31e10f8 RW |
4201 | |
4202 | (define-public r-allelicimbalance | |
4203 | (package | |
4204 | (name "r-allelicimbalance") | |
50e6f762 | 4205 | (version "1.24.0") |
f31e10f8 RW |
4206 | (source |
4207 | (origin | |
4208 | (method url-fetch) | |
4209 | (uri (bioconductor-uri "AllelicImbalance" version)) | |
4210 | (sha256 | |
4211 | (base32 | |
50e6f762 | 4212 | "0vy8w7ii2qljsmq8lr21lygkcrsshc7syyqhadlbxyj3scgi7kyc")))) |
f31e10f8 RW |
4213 | (properties |
4214 | `((upstream-name . "AllelicImbalance"))) | |
4215 | (build-system r-build-system) | |
4216 | (propagated-inputs | |
4217 | `(("r-annotationdbi" ,r-annotationdbi) | |
4218 | ("r-biocgenerics" ,r-biocgenerics) | |
4219 | ("r-biostrings" ,r-biostrings) | |
4220 | ("r-bsgenome" ,r-bsgenome) | |
4221 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4222 | ("r-genomicalignments" ,r-genomicalignments) | |
4223 | ("r-genomicfeatures" ,r-genomicfeatures) | |
4224 | ("r-genomicranges" ,r-genomicranges) | |
4225 | ("r-gridextra" ,r-gridextra) | |
4226 | ("r-gviz" ,r-gviz) | |
4227 | ("r-iranges" ,r-iranges) | |
4228 | ("r-lattice" ,r-lattice) | |
4229 | ("r-latticeextra" ,r-latticeextra) | |
4230 | ("r-nlme" ,r-nlme) | |
4231 | ("r-rsamtools" ,r-rsamtools) | |
4232 | ("r-s4vectors" ,r-s4vectors) | |
4233 | ("r-seqinr" ,r-seqinr) | |
4234 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
4235 | ("r-variantannotation" ,r-variantannotation))) | |
4236 | (home-page "https://github.com/pappewaio/AllelicImbalance") | |
4237 | (synopsis "Investigate allele-specific expression") | |
4238 | (description | |
4239 | "This package provides a framework for allele-specific expression | |
4240 | investigation using RNA-seq data.") | |
4241 | (license license:gpl3))) | |
ffe7029b RW |
4242 | |
4243 | (define-public r-aucell | |
4244 | (package | |
4245 | (name "r-aucell") | |
3a35d274 | 4246 | (version "1.8.0") |
ffe7029b RW |
4247 | (source |
4248 | (origin | |
4249 | (method url-fetch) | |
4250 | (uri (bioconductor-uri "AUCell" version)) | |
4251 | (sha256 | |
4252 | (base32 | |
3a35d274 | 4253 | "1g4mdq8z29fjxrfjng0fb3cvbph49mwds4ijsa2bn2k6f75dnzky")))) |
ffe7029b RW |
4254 | (properties `((upstream-name . "AUCell"))) |
4255 | (build-system r-build-system) | |
4256 | (propagated-inputs | |
3a35d274 RW |
4257 | `(("r-biocgenerics" ,r-biocgenerics) |
4258 | ("r-data-table" ,r-data-table) | |
ffe7029b RW |
4259 | ("r-gseabase" ,r-gseabase) |
4260 | ("r-mixtools" ,r-mixtools) | |
4261 | ("r-r-utils" ,r-r-utils) | |
3a35d274 | 4262 | ("r-s4vectors" ,r-s4vectors) |
ffe7029b RW |
4263 | ("r-shiny" ,r-shiny) |
4264 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
4265 | (home-page "https://bioconductor.org/packages/AUCell/") | |
4266 | (synopsis "Analysis of gene set activity in single-cell RNA-seq data") | |
4267 | (description | |
4268 | "AUCell allows to identify cells with active gene sets (e.g. signatures, | |
4269 | gene modules, etc) in single-cell RNA-seq data. AUCell uses the @dfn{Area | |
4270 | Under the Curve} (AUC) to calculate whether a critical subset of the input | |
4271 | gene set is enriched within the expressed genes for each cell. The | |
4272 | distribution of AUC scores across all the cells allows exploring the relative | |
4273 | expression of the signature. Since the scoring method is ranking-based, | |
4274 | AUCell is independent of the gene expression units and the normalization | |
4275 | procedure. In addition, since the cells are evaluated individually, it can | |
4276 | easily be applied to bigger datasets, subsetting the expression matrix if | |
4277 | needed.") | |
4278 | (license license:gpl3))) | |
5cfa4bff RW |
4279 | |
4280 | (define-public r-ebimage | |
4281 | (package | |
4282 | (name "r-ebimage") | |
ca7192a1 | 4283 | (version "4.28.1") |
5cfa4bff RW |
4284 | (source |
4285 | (origin | |
4286 | (method url-fetch) | |
4287 | (uri (bioconductor-uri "EBImage" version)) | |
4288 | (sha256 | |
4289 | (base32 | |
ca7192a1 | 4290 | "0q54q2nw6p1s4nrj1l8qz78m67xcysj2x82zs43my8iv2g9iifgs")))) |
5cfa4bff RW |
4291 | (properties `((upstream-name . "EBImage"))) |
4292 | (build-system r-build-system) | |
4293 | (propagated-inputs | |
4294 | `(("r-abind" ,r-abind) | |
4295 | ("r-biocgenerics" ,r-biocgenerics) | |
4296 | ("r-fftwtools" ,r-fftwtools) | |
4297 | ("r-htmltools" ,r-htmltools) | |
4298 | ("r-htmlwidgets" ,r-htmlwidgets) | |
4299 | ("r-jpeg" ,r-jpeg) | |
4300 | ("r-locfit" ,r-locfit) | |
4301 | ("r-png" ,r-png) | |
4302 | ("r-rcurl" ,r-rcurl) | |
4303 | ("r-tiff" ,r-tiff))) | |
4304 | (native-inputs | |
4305 | `(("r-knitr" ,r-knitr))) ; for vignettes | |
4306 | (home-page "https://github.com/aoles/EBImage") | |
4307 | (synopsis "Image processing and analysis toolbox for R") | |
4308 | (description | |
4309 | "EBImage provides general purpose functionality for image processing and | |
4310 | analysis. In the context of (high-throughput) microscopy-based cellular | |
4311 | assays, EBImage offers tools to segment cells and extract quantitative | |
4312 | cellular descriptors. This allows the automation of such tasks using the R | |
4313 | programming language and facilitates the use of other tools in the R | |
4314 | environment for signal processing, statistical modeling, machine learning and | |
4315 | visualization with image data.") | |
4316 | ;; Any version of the LGPL. | |
4317 | (license license:lgpl2.1+))) | |
51e98f7e RW |
4318 | |
4319 | (define-public r-yamss | |
4320 | (package | |
4321 | (name "r-yamss") | |
f0aaa448 | 4322 | (version "1.12.1") |
51e98f7e RW |
4323 | (source |
4324 | (origin | |
4325 | (method url-fetch) | |
4326 | (uri (bioconductor-uri "yamss" version)) | |
4327 | (sha256 | |
4328 | (base32 | |
f0aaa448 | 4329 | "12jr7hbrwhb1gfjadj1024hv80ra22miy46dn40nmsrbklkfn3rw")))) |
51e98f7e RW |
4330 | (build-system r-build-system) |
4331 | (propagated-inputs | |
4332 | `(("r-biocgenerics" ,r-biocgenerics) | |
4333 | ("r-data-table" ,r-data-table) | |
4334 | ("r-ebimage" ,r-ebimage) | |
4335 | ("r-iranges" ,r-iranges) | |
4336 | ("r-limma" ,r-limma) | |
4337 | ("r-matrix" ,r-matrix) | |
4338 | ("r-mzr" ,r-mzr) | |
4339 | ("r-s4vectors" ,r-s4vectors) | |
4340 | ("r-summarizedexperiment" | |
4341 | ,r-summarizedexperiment))) | |
4342 | (home-page "https://github.com/hansenlab/yamss") | |
4343 | (synopsis "Tools for high-throughput metabolomics") | |
4344 | (description | |
4345 | "This package provides tools to analyze and visualize high-throughput | |
9b19734c | 4346 | metabolomics data acquired using chromatography-mass spectrometry. These tools |
51e98f7e RW |
4347 | preprocess data in a way that enables reliable and powerful differential |
4348 | analysis.") | |
4349 | (license license:artistic2.0))) | |
398c4a93 RW |
4350 | |
4351 | (define-public r-gtrellis | |
4352 | (package | |
4353 | (name "r-gtrellis") | |
cf0a1cb3 | 4354 | (version "1.18.0") |
398c4a93 RW |
4355 | (source |
4356 | (origin | |
4357 | (method url-fetch) | |
4358 | (uri (bioconductor-uri "gtrellis" version)) | |
4359 | (sha256 | |
4360 | (base32 | |
cf0a1cb3 | 4361 | "0mgspmv6p1a2k98jyy2dfl0wpa2vh7bhnjfm2xaqmcsxzmbjhh9z")))) |
398c4a93 RW |
4362 | (build-system r-build-system) |
4363 | (propagated-inputs | |
4364 | `(("r-circlize" ,r-circlize) | |
4365 | ("r-genomicranges" ,r-genomicranges) | |
4366 | ("r-getoptlong" ,r-getoptlong) | |
4367 | ("r-iranges" ,r-iranges))) | |
4368 | (home-page "https://github.com/jokergoo/gtrellis") | |
4369 | (synopsis "Genome level Trellis layout") | |
4370 | (description | |
4371 | "Genome level Trellis graph visualizes genomic data conditioned by | |
4372 | genomic categories (e.g. chromosomes). For each genomic category, multiple | |
4373 | dimensional data which are represented as tracks describe different features | |
4374 | from different aspects. This package provides high flexibility to arrange | |
4375 | genomic categories and to add self-defined graphics in the plot.") | |
4376 | (license license:expat))) | |
28098414 RW |
4377 | |
4378 | (define-public r-somaticsignatures | |
4379 | (package | |
4380 | (name "r-somaticsignatures") | |
4f8e0487 | 4381 | (version "2.22.0") |
28098414 RW |
4382 | (source |
4383 | (origin | |
4384 | (method url-fetch) | |
4385 | (uri (bioconductor-uri "SomaticSignatures" version)) | |
4386 | (sha256 | |
4387 | (base32 | |
4f8e0487 | 4388 | "1gvrkahllwz38g3hn9pjlikhfqz19a4qglcqmyrxk7h9ybx5zy5z")))) |
28098414 RW |
4389 | (properties |
4390 | `((upstream-name . "SomaticSignatures"))) | |
4391 | (build-system r-build-system) | |
4392 | (propagated-inputs | |
4393 | `(("r-biobase" ,r-biobase) | |
4394 | ("r-biostrings" ,r-biostrings) | |
4395 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4396 | ("r-genomicranges" ,r-genomicranges) | |
4397 | ("r-ggbio" ,r-ggbio) | |
4398 | ("r-ggplot2" ,r-ggplot2) | |
4399 | ("r-iranges" ,r-iranges) | |
4400 | ("r-nmf" ,r-nmf) | |
4401 | ("r-pcamethods" ,r-pcamethods) | |
4402 | ("r-proxy" ,r-proxy) | |
4403 | ("r-reshape2" ,r-reshape2) | |
4404 | ("r-s4vectors" ,r-s4vectors) | |
4405 | ("r-variantannotation" ,r-variantannotation))) | |
4406 | (home-page "https://github.com/juliangehring/SomaticSignatures") | |
4407 | (synopsis "Somatic signatures") | |
4408 | (description | |
4409 | "This package identifies mutational signatures of @dfn{single nucleotide | |
4410 | variants} (SNVs). It provides a infrastructure related to the methodology | |
4411 | described in Nik-Zainal (2012, Cell), with flexibility in the matrix | |
4412 | decomposition algorithms.") | |
4413 | (license license:expat))) | |
303f2ed1 RW |
4414 | |
4415 | (define-public r-yapsa | |
4416 | (package | |
4417 | (name "r-yapsa") | |
580e4342 | 4418 | (version "1.12.0") |
303f2ed1 RW |
4419 | (source |
4420 | (origin | |
4421 | (method url-fetch) | |
4422 | (uri (bioconductor-uri "YAPSA" version)) | |
4423 | (sha256 | |
4424 | (base32 | |
580e4342 | 4425 | "132x51f8k8zyx6j8jk05x4lr9q1hlblgvr69wkhn0q3f8mhaj926")))) |
303f2ed1 RW |
4426 | (properties `((upstream-name . "YAPSA"))) |
4427 | (build-system r-build-system) | |
4428 | (propagated-inputs | |
4429 | `(("r-circlize" ,r-circlize) | |
4430 | ("r-complexheatmap" ,r-complexheatmap) | |
4431 | ("r-corrplot" ,r-corrplot) | |
4432 | ("r-dendextend" ,r-dendextend) | |
4433 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4434 | ("r-genomicranges" ,r-genomicranges) | |
4435 | ("r-getoptlong" ,r-getoptlong) | |
4436 | ("r-ggplot2" ,r-ggplot2) | |
4437 | ("r-gridextra" ,r-gridextra) | |
4438 | ("r-gtrellis" ,r-gtrellis) | |
4439 | ("r-keggrest" ,r-keggrest) | |
4440 | ("r-lsei" ,r-lsei) | |
4441 | ("r-pmcmr" ,r-pmcmr) | |
4442 | ("r-reshape2" ,r-reshape2) | |
4443 | ("r-somaticsignatures" ,r-somaticsignatures) | |
4444 | ("r-variantannotation" ,r-variantannotation))) | |
4445 | (home-page "https://bioconductor.org/packages/YAPSA/") | |
4446 | (synopsis "Yet another package for signature analysis") | |
4447 | (description | |
4448 | "This package provides functions and routines useful in the analysis of | |
4449 | somatic signatures (cf. L. Alexandrov et al., Nature 2013). In particular, | |
4450 | functions to perform a signature analysis with known signatures and a | |
4451 | signature analysis on @dfn{stratified mutational catalogue} (SMC) are | |
4452 | provided.") | |
4453 | (license license:gpl3))) | |
e99380d6 RW |
4454 | |
4455 | (define-public r-gcrma | |
4456 | (package | |
4457 | (name "r-gcrma") | |
2f90bab8 | 4458 | (version "2.58.0") |
e99380d6 RW |
4459 | (source |
4460 | (origin | |
4461 | (method url-fetch) | |
4462 | (uri (bioconductor-uri "gcrma" version)) | |
4463 | (sha256 | |
4464 | (base32 | |
2f90bab8 | 4465 | "0c9sa9ldlcpdcjdan8m4ndnyaisr6wbarq486sl44ikh7wf1csfx")))) |
e99380d6 RW |
4466 | (build-system r-build-system) |
4467 | (propagated-inputs | |
4468 | `(("r-affy" ,r-affy) | |
4469 | ("r-affyio" ,r-affyio) | |
4470 | ("r-biobase" ,r-biobase) | |
4471 | ("r-biocmanager" ,r-biocmanager) | |
4472 | ("r-biostrings" ,r-biostrings) | |
4473 | ("r-xvector" ,r-xvector))) | |
4474 | (home-page "https://bioconductor.org/packages/gcrma/") | |
4475 | (synopsis "Background adjustment using sequence information") | |
4476 | (description | |
4477 | "Gcrma adjusts for background intensities in Affymetrix array data which | |
4478 | include optical noise and @dfn{non-specific binding} (NSB). The main function | |
4479 | @code{gcrma} converts background adjusted probe intensities to expression | |
4480 | measures using the same normalization and summarization methods as a | |
4481 | @dfn{Robust Multiarray Average} (RMA). Gcrma uses probe sequence information | |
4482 | to estimate probe affinity to NSB. The sequence information is summarized in | |
4483 | a more complex way than the simple GC content. Instead, the base types (A, T, | |
4484 | G or C) at each position along the probe determine the affinity of each probe. | |
4485 | The parameters of the position-specific base contributions to the probe | |
4486 | affinity is estimated in an NSB experiment in which only NSB but no | |
4487 | gene-specific bidning is expected.") | |
4488 | ;; Any version of the LGPL | |
4489 | (license license:lgpl2.1+))) | |
4675b3cf RW |
4490 | |
4491 | (define-public r-simpleaffy | |
4492 | (package | |
4493 | (name "r-simpleaffy") | |
a87aa2ff | 4494 | (version "2.62.0") |
4675b3cf RW |
4495 | (source |
4496 | (origin | |
4497 | (method url-fetch) | |
4498 | (uri (bioconductor-uri "simpleaffy" version)) | |
4499 | (sha256 | |
4500 | (base32 | |
a87aa2ff | 4501 | "18bz3pfgp0f7906flrljx97ann8s71pnb8gpw7nah46n8vqc0xcs")))) |
4675b3cf RW |
4502 | (build-system r-build-system) |
4503 | (propagated-inputs | |
4504 | `(("r-affy" ,r-affy) | |
4505 | ("r-biobase" ,r-biobase) | |
4506 | ("r-biocgenerics" ,r-biocgenerics) | |
4507 | ("r-gcrma" ,r-gcrma) | |
4508 | ("r-genefilter" ,r-genefilter))) | |
4509 | (home-page "https://bioconductor.org/packages/simpleaffy/") | |
4510 | (synopsis "Very simple high level analysis of Affymetrix data") | |
4511 | (description | |
4512 | "This package provides high level functions for reading Affy @file{.CEL} | |
4513 | files, phenotypic data, and then computing simple things with it, such as | |
4514 | t-tests, fold changes and the like. It makes heavy use of the @code{affy} | |
4515 | library. It also has some basic scatter plot functions and mechanisms for | |
4516 | generating high resolution journal figures.") | |
4517 | (license license:gpl2+))) | |
f562c90a RW |
4518 | |
4519 | (define-public r-yaqcaffy | |
4520 | (package | |
4521 | (name "r-yaqcaffy") | |
87942b74 | 4522 | (version "1.46.0") |
f562c90a RW |
4523 | (source |
4524 | (origin | |
4525 | (method url-fetch) | |
4526 | (uri (bioconductor-uri "yaqcaffy" version)) | |
4527 | (sha256 | |
4528 | (base32 | |
87942b74 | 4529 | "0kzzqsf1lfbcmy95w2z0c9qrvp7mbwm50k2l9wvz3xa5wz6xa7gz")))) |
f562c90a RW |
4530 | (build-system r-build-system) |
4531 | (propagated-inputs | |
4532 | `(("r-simpleaffy" ,r-simpleaffy))) | |
4533 | (home-page "https://bioconductor.org/packages/yaqcaffy/") | |
4534 | (synopsis "Affymetrix quality control and reproducibility analysis") | |
4535 | (description | |
4536 | "This is a package that can be used for quality control of Affymetrix | |
4537 | GeneChip expression data and reproducibility analysis of human whole genome | |
4538 | chips with the MAQC reference datasets.") | |
4539 | (license license:artistic2.0))) | |
59cf2629 RW |
4540 | |
4541 | (define-public r-quantro | |
4542 | (package | |
4543 | (name "r-quantro") | |
eb697ff5 | 4544 | (version "1.20.0") |
59cf2629 RW |
4545 | (source |
4546 | (origin | |
4547 | (method url-fetch) | |
4548 | (uri (bioconductor-uri "quantro" version)) | |
4549 | (sha256 | |
4550 | (base32 | |
eb697ff5 | 4551 | "09f3x1j50ll5hhn3qwys5x06mii3fqsrk6dkvsxai0kdxv9cjz9m")))) |
59cf2629 RW |
4552 | (build-system r-build-system) |
4553 | (propagated-inputs | |
4554 | `(("r-biobase" ,r-biobase) | |
4555 | ("r-doparallel" ,r-doparallel) | |
4556 | ("r-foreach" ,r-foreach) | |
4557 | ("r-ggplot2" ,r-ggplot2) | |
4558 | ("r-iterators" ,r-iterators) | |
4559 | ("r-minfi" ,r-minfi) | |
4560 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
4561 | (home-page "https://bioconductor.org/packages/quantro/") | |
4562 | (synopsis "Test for when to use quantile normalization") | |
4563 | (description | |
4564 | "This package provides a data-driven test for the assumptions of quantile | |
4565 | normalization using raw data such as objects that inherit eSets (e.g. | |
4566 | ExpressionSet, MethylSet). Group level information about each sample (such as | |
4567 | Tumor / Normal status) must also be provided because the test assesses if | |
4568 | there are global differences in the distributions between the user-defined | |
4569 | groups.") | |
4570 | (license license:gpl3+))) | |
98a2af31 RW |
4571 | |
4572 | (define-public r-yarn | |
4573 | (package | |
4574 | (name "r-yarn") | |
94fdea12 | 4575 | (version "1.12.0") |
98a2af31 RW |
4576 | (source |
4577 | (origin | |
4578 | (method url-fetch) | |
4579 | (uri (bioconductor-uri "yarn" version)) | |
4580 | (sha256 | |
4581 | (base32 | |
94fdea12 | 4582 | "0891a10adkhm1zpm7fpcxc2xfxjf9yrpckaz87b2wdjdiwivc4cp")))) |
98a2af31 RW |
4583 | (build-system r-build-system) |
4584 | (propagated-inputs | |
4585 | `(("r-biobase" ,r-biobase) | |
4586 | ("r-biomart" ,r-biomart) | |
4587 | ("r-downloader" ,r-downloader) | |
4588 | ("r-edger" ,r-edger) | |
4589 | ("r-gplots" ,r-gplots) | |
4590 | ("r-limma" ,r-limma) | |
4591 | ("r-matrixstats" ,r-matrixstats) | |
4592 | ("r-preprocesscore" ,r-preprocesscore) | |
4593 | ("r-quantro" ,r-quantro) | |
4594 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
4595 | ("r-readr" ,r-readr))) | |
4596 | (home-page "https://bioconductor.org/packages/yarn/") | |
4597 | (synopsis "Robust multi-condition RNA-Seq preprocessing and normalization") | |
4598 | (description | |
4599 | "Expedite large RNA-Seq analyses using a combination of previously | |
4600 | developed tools. YARN is meant to make it easier for the user in performing | |
4601 | basic mis-annotation quality control, filtering, and condition-aware | |
4602 | normalization. YARN leverages many Bioconductor tools and statistical | |
4603 | techniques to account for the large heterogeneity and sparsity found in very | |
4604 | large RNA-seq experiments.") | |
4605 | (license license:artistic2.0))) | |
a6e1eb1a RW |
4606 | |
4607 | (define-public r-roar | |
4608 | (package | |
4609 | (name "r-roar") | |
f0dd0fec | 4610 | (version "1.22.0") |
a6e1eb1a RW |
4611 | (source |
4612 | (origin | |
4613 | (method url-fetch) | |
4614 | (uri (bioconductor-uri "roar" version)) | |
4615 | (sha256 | |
4616 | (base32 | |
f0dd0fec | 4617 | "1nqw0agx9x8ycdf0gw17fdlnmzpw9x3zig1wcy10xpyhyjdbbi06")))) |
a6e1eb1a RW |
4618 | (build-system r-build-system) |
4619 | (propagated-inputs | |
4620 | `(("r-biocgenerics" ,r-biocgenerics) | |
4621 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4622 | ("r-genomicalignments" ,r-genomicalignments) | |
4623 | ("r-genomicranges" ,r-genomicranges) | |
4624 | ("r-iranges" ,r-iranges) | |
4625 | ("r-rtracklayer" ,r-rtracklayer) | |
4626 | ("r-s4vectors" ,r-s4vectors) | |
4627 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
4628 | (home-page "https://github.com/vodkatad/roar/") | |
4629 | (synopsis "Identify differential APA usage from RNA-seq alignments") | |
4630 | (description | |
4631 | "This package provides tools for identifying preferential usage of APA | |
4632 | sites, comparing two biological conditions, starting from known alternative | |
4633 | sites and alignments obtained from standard RNA-seq experiments.") | |
4634 | (license license:gpl3))) | |
50d91770 RW |
4635 | |
4636 | (define-public r-xbseq | |
4637 | (package | |
4638 | (name "r-xbseq") | |
1f0101ae | 4639 | (version "1.18.0") |
50d91770 RW |
4640 | (source |
4641 | (origin | |
4642 | (method url-fetch) | |
4643 | (uri (bioconductor-uri "XBSeq" version)) | |
4644 | (sha256 | |
4645 | (base32 | |
1f0101ae | 4646 | "1qr5gvf8jcx6r0ac7d2wmnikswmp3k71lirnw7dyr6fndzrdz9lp")))) |
50d91770 RW |
4647 | (properties `((upstream-name . "XBSeq"))) |
4648 | (build-system r-build-system) | |
4649 | (propagated-inputs | |
4650 | `(("r-biobase" ,r-biobase) | |
4651 | ("r-deseq2" ,r-deseq2) | |
4652 | ("r-dplyr" ,r-dplyr) | |
4653 | ("r-ggplot2" ,r-ggplot2) | |
4654 | ("r-locfit" ,r-locfit) | |
4655 | ("r-magrittr" ,r-magrittr) | |
4656 | ("r-matrixstats" ,r-matrixstats) | |
4657 | ("r-pracma" ,r-pracma) | |
4658 | ("r-roar" ,r-roar))) | |
4659 | (home-page "https://github.com/Liuy12/XBSeq") | |
4660 | (synopsis "Test for differential expression for RNA-seq data") | |
4661 | (description | |
4662 | "XBSeq is a novel algorithm for testing RNA-seq @dfn{differential | |
4663 | expression} (DE), where a statistical model was established based on the | |
4664 | assumption that observed signals are the convolution of true expression | |
4665 | signals and sequencing noises. The mapped reads in non-exonic regions are | |
4666 | considered as sequencing noises, which follows a Poisson distribution. Given | |
4667 | measurable observed signal and background noise from RNA-seq data, true | |
4668 | expression signals, assuming governed by the negative binomial distribution, | |
4669 | can be delineated and thus the accurate detection of differential expressed | |
4670 | genes.") | |
4671 | (license license:gpl3+))) | |
c8310056 RW |
4672 | |
4673 | (define-public r-massspecwavelet | |
4674 | (package | |
4675 | (name "r-massspecwavelet") | |
a07ee258 | 4676 | (version "1.52.0") |
c8310056 RW |
4677 | (source |
4678 | (origin | |
4679 | (method url-fetch) | |
4680 | (uri (bioconductor-uri "MassSpecWavelet" version)) | |
4681 | (sha256 | |
4682 | (base32 | |
a07ee258 | 4683 | "0xnj3ncrwvr2b8msi3g77mgzj0zaksn3lgqdn1abh0ww5wgk83v7")))) |
c8310056 RW |
4684 | (properties |
4685 | `((upstream-name . "MassSpecWavelet"))) | |
4686 | (build-system r-build-system) | |
4687 | (propagated-inputs | |
4688 | `(("r-waveslim" ,r-waveslim))) | |
4689 | (home-page "https://bioconductor.org/packages/MassSpecWavelet/") | |
4690 | (synopsis "Mass spectrum processing by wavelet-based algorithms") | |
4691 | (description | |
4692 | "The MassSpecWavelet package aims to process @dfn{Mass Spectrometry} (MS) | |
4693 | data mainly through the use of wavelet transforms. It supports peak detection | |
4694 | based on @dfn{Continuous Wavelet Transform} (CWT).") | |
4695 | (license license:lgpl2.0+))) | |
ec12e537 RW |
4696 | |
4697 | (define-public r-xcms | |
4698 | (package | |
4699 | (name "r-xcms") | |
a2512e43 | 4700 | (version "3.8.2") |
ec12e537 RW |
4701 | (source |
4702 | (origin | |
4703 | (method url-fetch) | |
4704 | (uri (bioconductor-uri "xcms" version)) | |
4705 | (sha256 | |
4706 | (base32 | |
a2512e43 | 4707 | "0bfl56v3l6k31i11l09nx1yqfjy6z5yragm6k83z4w0mpgk18y7g")))) |
ec12e537 RW |
4708 | (build-system r-build-system) |
4709 | (propagated-inputs | |
4710 | `(("r-biobase" ,r-biobase) | |
4711 | ("r-biocgenerics" ,r-biocgenerics) | |
4712 | ("r-biocparallel" ,r-biocparallel) | |
4fb52345 | 4713 | ("r-iranges" ,r-iranges) |
ec12e537 RW |
4714 | ("r-lattice" ,r-lattice) |
4715 | ("r-massspecwavelet" ,r-massspecwavelet) | |
4716 | ("r-msnbase" ,r-msnbase) | |
4717 | ("r-multtest" ,r-multtest) | |
4718 | ("r-mzr" ,r-mzr) | |
4719 | ("r-plyr" ,r-plyr) | |
4720 | ("r-protgenerics" ,r-protgenerics) | |
4721 | ("r-rann" ,r-rann) | |
4722 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
4723 | ("r-robustbase" ,r-robustbase) | |
4724 | ("r-s4vectors" ,r-s4vectors))) | |
4725 | (home-page "https://bioconductor.org/packages/xcms/") | |
4726 | (synopsis "LC/MS and GC/MS mass spectrometry data analysis") | |
4727 | (description | |
4728 | "This package provides a framework for processing and visualization of | |
4729 | chromatographically separated and single-spectra mass spectral data. It | |
4730 | imports from AIA/ANDI NetCDF, mzXML, mzData and mzML files. It preprocesses | |
4731 | data for high-throughput, untargeted analyte profiling.") | |
4732 | (license license:gpl2+))) | |
8830664d RW |
4733 | |
4734 | (define-public r-wrench | |
4735 | (package | |
4736 | (name "r-wrench") | |
92f40538 | 4737 | (version "1.4.0") |
8830664d RW |
4738 | (source |
4739 | (origin | |
4740 | (method url-fetch) | |
4741 | (uri (bioconductor-uri "Wrench" version)) | |
4742 | (sha256 | |
4743 | (base32 | |
92f40538 | 4744 | "1s8d7jn0dk5zk2fhvsd4sgicypz4c41nzf19nqzcwb9bd6asgrwm")))) |
8830664d RW |
4745 | (properties `((upstream-name . "Wrench"))) |
4746 | (build-system r-build-system) | |
4747 | (propagated-inputs | |
4748 | `(("r-limma" ,r-limma) | |
4749 | ("r-locfit" ,r-locfit) | |
4750 | ("r-matrixstats" ,r-matrixstats))) | |
4751 | (home-page "https://github.com/HCBravoLab/Wrench") | |
4752 | (synopsis "Wrench normalization for sparse count data") | |
4753 | (description | |
4754 | "Wrench is a package for normalization sparse genomic count data, like | |
4755 | that arising from 16s metagenomic surveys.") | |
4756 | (license license:artistic2.0))) | |
b9b8b447 RW |
4757 | |
4758 | (define-public r-wiggleplotr | |
4759 | (package | |
4760 | (name "r-wiggleplotr") | |
25db5611 | 4761 | (version "1.10.1") |
b9b8b447 RW |
4762 | (source |
4763 | (origin | |
4764 | (method url-fetch) | |
4765 | (uri (bioconductor-uri "wiggleplotr" version)) | |
4766 | (sha256 | |
4767 | (base32 | |
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b9b8b447 RW |
4769 | (build-system r-build-system) |
4770 | (propagated-inputs | |
4771 | `(("r-assertthat" ,r-assertthat) | |
4772 | ("r-cowplot" ,r-cowplot) | |
4773 | ("r-dplyr" ,r-dplyr) | |
4774 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4775 | ("r-genomicranges" ,r-genomicranges) | |
4776 | ("r-ggplot2" ,r-ggplot2) | |
4777 | ("r-iranges" ,r-iranges) | |
4778 | ("r-purrr" ,r-purrr) | |
4779 | ("r-rtracklayer" ,r-rtracklayer) | |
4780 | ("r-s4vectors" ,r-s4vectors))) | |
4781 | (home-page "https://bioconductor.org/packages/wiggleplotr/") | |
4782 | (synopsis "Make read coverage plots from BigWig files") | |
4783 | (description | |
4784 | "This package provides tools to visualize read coverage from sequencing | |
4785 | experiments together with genomic annotations (genes, transcripts, peaks). | |
4786 | Introns of long transcripts can be rescaled to a fixed length for better | |
4787 | visualization of exonic read coverage.") | |
4788 | (license license:asl2.0))) | |
7b5101c5 RW |
4789 | |
4790 | (define-public r-widgettools | |
4791 | (package | |
4792 | (name "r-widgettools") | |
1a2569e4 | 4793 | (version "1.64.0") |
7b5101c5 RW |
4794 | (source |
4795 | (origin | |
4796 | (method url-fetch) | |
4797 | (uri (bioconductor-uri "widgetTools" version)) | |
4798 | (sha256 | |
4799 | (base32 | |
1a2569e4 | 4800 | "1nqy3icayacv5mlv5s5xgfli0dqzancs6zpffrl5p237c994nyr5")))) |
7b5101c5 RW |
4801 | (properties `((upstream-name . "widgetTools"))) |
4802 | (build-system r-build-system) | |
4803 | (home-page "https://bioconductor.org/packages/widgetTools/") | |
4804 | (synopsis "Tools for creating interactive tcltk widgets") | |
4805 | (description | |
337bdc17 | 4806 | "This package contains tools to support the construction of tcltk |
7b5101c5 RW |
4807 | widgets in R.") |
4808 | ;; Any version of the LGPL. | |
4809 | (license license:lgpl3+))) | |
6b12f213 RW |
4810 | |
4811 | (define-public r-webbioc | |
4812 | (package | |
4813 | (name "r-webbioc") | |
316bcd07 | 4814 | (version "1.58.0") |
6b12f213 RW |
4815 | (source |
4816 | (origin | |
4817 | (method url-fetch) | |
4818 | (uri (bioconductor-uri "webbioc" version)) | |
4819 | (sha256 | |
4820 | (base32 | |
316bcd07 | 4821 | "1cwrmvh1l603k6j1r425c4vrqp0zf0x7bgx7y1wnbq4r7yc5sp62")))) |
6b12f213 RW |
4822 | (build-system r-build-system) |
4823 | (inputs | |
4824 | `(("netpbm" ,netpbm) | |
4825 | ("perl" ,perl))) | |
4826 | (propagated-inputs | |
4827 | `(("r-affy" ,r-affy) | |
4828 | ("r-annaffy" ,r-annaffy) | |
4829 | ("r-biobase" ,r-biobase) | |
4830 | ("r-biocmanager" ,r-biocmanager) | |
4831 | ("r-gcrma" ,r-gcrma) | |
4832 | ("r-multtest" ,r-multtest) | |
4833 | ("r-qvalue" ,r-qvalue) | |
4834 | ("r-vsn" ,r-vsn))) | |
4835 | (home-page "https://www.bioconductor.org/") | |
4836 | (synopsis "Bioconductor web interface") | |
4837 | (description | |
4838 | "This package provides an integrated web interface for doing microarray | |
4839 | analysis using several of the Bioconductor packages. It is intended to be | |
4840 | deployed as a centralized bioinformatics resource for use by many users. | |
4841 | Currently only Affymetrix oligonucleotide analysis is supported.") | |
4842 | (license license:gpl2+))) | |
9800d859 RW |
4843 | |
4844 | (define-public r-zfpkm | |
4845 | (package | |
4846 | (name "r-zfpkm") | |
18b93e03 | 4847 | (version "1.8.0") |
9800d859 RW |
4848 | (source |
4849 | (origin | |
4850 | (method url-fetch) | |
4851 | (uri (bioconductor-uri "zFPKM" version)) | |
4852 | (sha256 | |
4853 | (base32 | |
18b93e03 | 4854 | "1hg0vc0ns8d4jpddn1v5a5m13a033b0wf1al01pb1lvmx5mzzr2n")))) |
9800d859 RW |
4855 | (properties `((upstream-name . "zFPKM"))) |
4856 | (build-system r-build-system) | |
4857 | (propagated-inputs | |
4858 | `(("r-checkmate" ,r-checkmate) | |
4859 | ("r-dplyr" ,r-dplyr) | |
4860 | ("r-ggplot2" ,r-ggplot2) | |
4861 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
4862 | ("r-tidyr" ,r-tidyr))) | |
4863 | (home-page "https://github.com/ronammar/zFPKM/") | |
4864 | (synopsis "Functions to facilitate zFPKM transformations") | |
4865 | (description | |
4866 | "This is a package to perform the zFPKM transform on RNA-seq FPKM data. | |
4867 | This algorithm is based on the publication by Hart et al., 2013 (Pubmed ID | |
4868 | 24215113).") | |
4869 | (license license:gpl3))) | |
2bdc88fc RW |
4870 | |
4871 | (define-public r-rbowtie2 | |
4872 | (package | |
4873 | (name "r-rbowtie2") | |
c5a4c5a1 | 4874 | (version "1.8.0") |
2bdc88fc RW |
4875 | (source |
4876 | (origin | |
4877 | (method url-fetch) | |
4878 | (uri (bioconductor-uri "Rbowtie2" version)) | |
4879 | (sha256 | |
4880 | (base32 | |
c5a4c5a1 | 4881 | "1b7x42n9zisi2w2wwfc0c39j8s9868imyr0ysqgswf6l5mv9ivc5")))) |
2bdc88fc RW |
4882 | (properties `((upstream-name . "Rbowtie2"))) |
4883 | (build-system r-build-system) | |
4884 | (inputs | |
4885 | `(("zlib" ,zlib))) | |
4886 | (home-page "https://bioconductor.org/packages/Rbowtie2/") | |
4887 | (synopsis "R wrapper for Bowtie2 and AdapterRemoval") | |
4888 | (description | |
4889 | "This package provides an R wrapper of the popular @code{bowtie2} | |
4890 | sequencing reads aligner and @code{AdapterRemoval}, a convenient tool for | |
4891 | rapid adapter trimming, identification, and read merging.") | |
4892 | (license license:gpl3+))) | |
5622628f RW |
4893 | |
4894 | (define-public r-progeny | |
4895 | (package | |
4896 | (name "r-progeny") | |
82d87ce0 | 4897 | (version "1.8.0") |
5622628f RW |
4898 | (source |
4899 | (origin | |
4900 | (method url-fetch) | |
4901 | (uri (bioconductor-uri "progeny" version)) | |
4902 | (sha256 | |
4903 | (base32 | |
82d87ce0 | 4904 | "0j3kxjj7xmmwb29p87n3bw7bl38gcb94jrpw32126a578rf1pfrq")))) |
5622628f RW |
4905 | (build-system r-build-system) |
4906 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
4907 | (home-page "https://github.com/saezlab/progeny") | |
4908 | (synopsis "Pathway responsive gene activity inference") | |
4909 | (description | |
4910 | "This package provides a function to infer pathway activity from gene | |
4911 | expression. It contains the linear model inferred in the publication | |
4912 | \"Perturbation-response genes reveal signaling footprints in cancer gene | |
4913 | expression\".") | |
4914 | (license license:asl2.0))) | |
307586c1 RW |
4915 | |
4916 | (define-public r-arrmnormalization | |
4917 | (package | |
4918 | (name "r-arrmnormalization") | |
4f0d8588 | 4919 | (version "1.26.0") |
307586c1 RW |
4920 | (source |
4921 | (origin | |
4922 | (method url-fetch) | |
4923 | (uri (bioconductor-uri "ARRmNormalization" version)) | |
4924 | (sha256 | |
4925 | (base32 | |
4f0d8588 | 4926 | "0jj81q454nyh4hr5c56q1hv7i4ynx3rwnvpv08w34a6m77122bi1")))) |
307586c1 RW |
4927 | (properties |
4928 | `((upstream-name . "ARRmNormalization"))) | |
4929 | (build-system r-build-system) | |
4930 | (propagated-inputs `(("r-arrmdata" ,r-arrmdata))) | |
4931 | (home-page "https://bioconductor.org/packages/ARRmNormalization/") | |
4932 | (synopsis "Adaptive robust regression normalization for methylation data") | |
4933 | (description | |
4934 | "This is a package to perform the @dfn{Adaptive Robust Regression | |
4935 | method} (ARRm) for the normalization of methylation data from the Illumina | |
4936 | Infinium HumanMethylation 450k assay.") | |
4937 | (license license:artistic2.0))) | |
fbf34949 RW |
4938 | |
4939 | (define-public r-biocfilecache | |
4940 | (package | |
4941 | (name "r-biocfilecache") | |
97e31700 | 4942 | (version "1.10.2") |
fbf34949 RW |
4943 | (source |
4944 | (origin | |
4945 | (method url-fetch) | |
4946 | (uri (bioconductor-uri "BiocFileCache" version)) | |
4947 | (sha256 | |
4948 | (base32 | |
97e31700 | 4949 | "0jivhn95y6zv5ryamqk6nyd4l8nlskq64j362l9ml9qw746v0ja6")))) |
fbf34949 RW |
4950 | (properties `((upstream-name . "BiocFileCache"))) |
4951 | (build-system r-build-system) | |
4952 | (propagated-inputs | |
4953 | `(("r-curl" ,r-curl) | |
4954 | ("r-dbi" ,r-dbi) | |
4955 | ("r-dbplyr" ,r-dbplyr) | |
4956 | ("r-dplyr" ,r-dplyr) | |
4957 | ("r-httr" ,r-httr) | |
4958 | ("r-rappdirs" ,r-rappdirs) | |
4959 | ("r-rsqlite" ,r-rsqlite))) | |
4960 | (home-page "https://bioconductor.org/packages/BiocFileCache/") | |
4961 | (synopsis "Manage files across sessions") | |
4962 | (description | |
4963 | "This package creates a persistent on-disk cache of files that the user | |
4964 | can add, update, and retrieve. It is useful for managing resources (such as | |
4965 | custom Txdb objects) that are costly or difficult to create, web resources, | |
4966 | and data files used across sessions.") | |
4967 | (license license:artistic2.0))) | |
8c42f8f6 RW |
4968 | |
4969 | (define-public r-iclusterplus | |
4970 | (package | |
4971 | (name "r-iclusterplus") | |
049de95d | 4972 | (version "1.22.0") |
8c42f8f6 RW |
4973 | (source |
4974 | (origin | |
4975 | (method url-fetch) | |
4976 | (uri (bioconductor-uri "iClusterPlus" version)) | |
4977 | (sha256 | |
4978 | (base32 | |
049de95d | 4979 | "1dzgfzf2x8m62hssvsn1zzag7m444kyxj2vpdxl9nk859dr5pf37")))) |
8c42f8f6 RW |
4980 | (properties `((upstream-name . "iClusterPlus"))) |
4981 | (build-system r-build-system) | |
4982 | (native-inputs `(("gfortran" ,gfortran))) | |
4983 | (home-page "https://bioconductor.org/packages/iClusterPlus/") | |
4984 | (synopsis "Integrative clustering of multi-type genomic data") | |
4985 | (description | |
4986 | "iClusterPlus is developed for integrative clustering analysis of | |
4987 | multi-type genomic data and is an enhanced version of iCluster proposed and | |
4988 | developed by Shen, Olshen and Ladanyi (2009). Multi-type genomic data arise | |
4989 | from the experiments where biological samples (e.g. tumor samples) are | |
4990 | analyzed by multiple techniques, for instance, @dfn{array comparative genomic | |
4991 | hybridization} (aCGH), gene expression microarray, RNA-seq and DNA-seq, and so | |
4992 | on. In the iClusterPlus model, binary observations such as somatic mutation | |
4993 | are modeled as Binomial processes; categorical observations such as copy | |
4994 | number states are realizations of Multinomial random variables; counts are | |
4995 | modeled as Poisson random processes; and continuous measures are modeled by | |
4996 | Gaussian distributions.") | |
4997 | (license license:gpl2+))) | |
4d06ef4b RW |
4998 | |
4999 | (define-public r-rbowtie | |
5000 | (package | |
5001 | (name "r-rbowtie") | |
02684bec | 5002 | (version "1.26.0") |
4d06ef4b RW |
5003 | (source |
5004 | (origin | |
5005 | (method url-fetch) | |
5006 | (uri (bioconductor-uri "Rbowtie" version)) | |
5007 | (sha256 | |
5008 | (base32 | |
02684bec | 5009 | "0yy31xhdmf6xb21wlhmxxwfqpm0nil39pb2cs3pq5ia758lb88z4")))) |
4d06ef4b RW |
5010 | (properties `((upstream-name . "Rbowtie"))) |
5011 | (build-system r-build-system) | |
5012 | (inputs | |
5013 | `(("zlib" ,zlib))) | |
5014 | (home-page "https://bioconductor.org/packages/Rbowtie/") | |
5015 | (synopsis "R bowtie wrapper") | |
5016 | (description | |
5017 | "This package provides an R wrapper around the popular bowtie short read | |
5018 | aligner and around SpliceMap, a de novo splice junction discovery and | |
5019 | alignment tool.") | |
5020 | (license license:artistic2.0))) | |
14441539 RW |
5021 | |
5022 | (define-public r-sgseq | |
5023 | (package | |
5024 | (name "r-sgseq") | |
2cebc5d1 | 5025 | (version "1.20.0") |
14441539 RW |
5026 | (source |
5027 | (origin | |
5028 | (method url-fetch) | |
5029 | (uri (bioconductor-uri "SGSeq" version)) | |
5030 | (sha256 | |
5031 | (base32 | |
2cebc5d1 | 5032 | "0950iv08wd0kjaw55rjn7m6syklvrabwr2zqq74wzyc5afyk2mrw")))) |
14441539 RW |
5033 | (properties `((upstream-name . "SGSeq"))) |
5034 | (build-system r-build-system) | |
5035 | (propagated-inputs | |
5036 | `(("r-annotationdbi" ,r-annotationdbi) | |
5037 | ("r-biocgenerics" ,r-biocgenerics) | |
5038 | ("r-biostrings" ,r-biostrings) | |
5039 | ("r-genomeinfodb" ,r-genomeinfodb) | |
5040 | ("r-genomicalignments" ,r-genomicalignments) | |
5041 | ("r-genomicfeatures" ,r-genomicfeatures) | |
5042 | ("r-genomicranges" ,r-genomicranges) | |
5043 | ("r-igraph" ,r-igraph) | |
5044 | ("r-iranges" ,r-iranges) | |
5045 | ("r-rsamtools" ,r-rsamtools) | |
5046 | ("r-rtracklayer" ,r-rtracklayer) | |
5047 | ("r-runit" ,r-runit) | |
5048 | ("r-s4vectors" ,r-s4vectors) | |
5049 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
5050 | (home-page "https://bioconductor.org/packages/SGSeq/") | |
5051 | (synopsis "Splice event prediction and quantification from RNA-seq data") | |
5052 | (description | |
5053 | "SGSeq is a package for analyzing splice events from RNA-seq data. Input | |
5054 | data are RNA-seq reads mapped to a reference genome in BAM format. Genes are | |
5055 | represented as a splice graph, which can be obtained from existing annotation | |
5056 | or predicted from the mapped sequence reads. Splice events are identified | |
5057 | from the graph and are quantified locally using structurally compatible reads | |
5058 | at the start or end of each splice variant. The software includes functions | |
5059 | for splice event prediction, quantification, visualization and | |
5060 | interpretation.") | |
5061 | (license license:artistic2.0))) | |
58656064 RW |
5062 | |
5063 | (define-public r-rhisat2 | |
5064 | (package | |
5065 | (name "r-rhisat2") | |
3dd2450e | 5066 | (version "1.2.0") |
58656064 RW |
5067 | (source |
5068 | (origin | |
5069 | (method url-fetch) | |
5070 | (uri (bioconductor-uri "Rhisat2" version)) | |
5071 | (sha256 | |
5072 | (base32 | |
3dd2450e | 5073 | "02fn5cm8sj2s9x00505y3iyipn1r3lpvpwpjy2pdxdbpmhb5hy49")))) |
58656064 RW |
5074 | (properties `((upstream-name . "Rhisat2"))) |
5075 | (build-system r-build-system) | |
3dd2450e RW |
5076 | (arguments |
5077 | `(#:phases | |
5078 | (modify-phases %standard-phases | |
5079 | (add-after 'unpack 'make-reproducible | |
5080 | (lambda _ | |
5081 | (substitute* "src/Makefile" | |
5082 | (("`hostname`") "guix") | |
5083 | (("`date`") "0") | |
5084 | ;; Avoid shelling out to "which". | |
5085 | (("^CC =.*") (which "gcc")) | |
5086 | (("^CPP =.*") (which "g++"))) | |
5087 | #t))))) | |
58656064 RW |
5088 | (propagated-inputs |
5089 | `(("r-genomicfeatures" ,r-genomicfeatures) | |
5090 | ("r-genomicranges" ,r-genomicranges) | |
5091 | ("r-sgseq" ,r-sgseq))) | |
5092 | (home-page "https://github.com/fmicompbio/Rhisat2") | |
5093 | (synopsis "R Wrapper for HISAT2 sequence aligner") | |
5094 | (description | |
5095 | "This package provides an R interface to the HISAT2 spliced short-read | |
5096 | aligner by Kim et al. (2015). The package contains wrapper functions to | |
5097 | create a genome index and to perform the read alignment to the generated | |
5098 | index.") | |
5099 | (license license:gpl3))) | |
5e0241db RW |
5100 | |
5101 | (define-public r-quasr | |
5102 | (package | |
5103 | (name "r-quasr") | |
a15e52ec | 5104 | (version "1.26.0") |
5e0241db RW |
5105 | (source |
5106 | (origin | |
5107 | (method url-fetch) | |
5108 | (uri (bioconductor-uri "QuasR" version)) | |
5109 | (sha256 | |
5110 | (base32 | |
a15e52ec | 5111 | "07m5q7wasapj2984kwy897510flbhvz7x0fgs7q2vm5wjhfzdrgv")))) |
5e0241db RW |
5112 | (properties `((upstream-name . "QuasR"))) |
5113 | (build-system r-build-system) | |
5114 | (inputs | |
5115 | `(("zlib" ,zlib))) | |
5116 | (propagated-inputs | |
5117 | `(("r-annotationdbi" ,r-annotationdbi) | |
5118 | ("r-biobase" ,r-biobase) | |
5119 | ("r-biocgenerics" ,r-biocgenerics) | |
5120 | ("r-biocmanager" ,r-biocmanager) | |
5121 | ("r-biocparallel" ,r-biocparallel) | |
5122 | ("r-biostrings" ,r-biostrings) | |
5123 | ("r-bsgenome" ,r-bsgenome) | |
5124 | ("r-genomeinfodb" ,r-genomeinfodb) | |
5125 | ("r-genomicalignments" ,r-genomicalignments) | |
5126 | ("r-genomicfeatures" ,r-genomicfeatures) | |
5127 | ("r-genomicfiles" ,r-genomicfiles) | |
5128 | ("r-genomicranges" ,r-genomicranges) | |
5129 | ("r-iranges" ,r-iranges) | |
5130 | ("r-rbowtie" ,r-rbowtie) | |
5131 | ("r-rhisat2" ,r-rhisat2) | |
5132 | ("r-rhtslib" ,r-rhtslib) | |
5133 | ("r-rsamtools" ,r-rsamtools) | |
5134 | ("r-rtracklayer" ,r-rtracklayer) | |
5135 | ("r-s4vectors" ,r-s4vectors) | |
5136 | ("r-shortread" ,r-shortread))) | |
5137 | (home-page "https://bioconductor.org/packages/QuasR/") | |
5138 | (synopsis "Quantify and annotate short reads in R") | |
5139 | (description | |
5140 | "This package provides a framework for the quantification and analysis of | |
5141 | short genomic reads. It covers a complete workflow starting from raw sequence | |
5142 | reads, over creation of alignments and quality control plots, to the | |
5143 | quantification of genomic regions of interest.") | |
5144 | (license license:gpl2))) | |
496b024f RW |
5145 | |
5146 | (define-public r-rqc | |
5147 | (package | |
5148 | (name "r-rqc") | |
11db82b0 | 5149 | (version "1.20.0") |
496b024f RW |
5150 | (source |
5151 | (origin | |
5152 | (method url-fetch) | |
5153 | (uri (bioconductor-uri "Rqc" version)) | |
5154 | (sha256 | |
5155 | (base32 | |
11db82b0 | 5156 | "1nxkrb9kx41g050yz935yrl9pjkakhr8v6whxcvr72gg4r9m2x3m")))) |
496b024f RW |
5157 | (properties `((upstream-name . "Rqc"))) |
5158 | (build-system r-build-system) | |
5159 | (propagated-inputs | |
5160 | `(("r-biocgenerics" ,r-biocgenerics) | |
5161 | ("r-biocparallel" ,r-biocparallel) | |
5162 | ("r-biocstyle" ,r-biocstyle) | |
5163 | ("r-biostrings" ,r-biostrings) | |
5164 | ("r-biovizbase" ,r-biovizbase) | |
5165 | ("r-genomicalignments" ,r-genomicalignments) | |
5166 | ("r-genomicfiles" ,r-genomicfiles) | |
5167 | ("r-ggplot2" ,r-ggplot2) | |
5168 | ("r-iranges" ,r-iranges) | |
5169 | ("r-knitr" ,r-knitr) | |
5170 | ("r-markdown" ,r-markdown) | |
5171 | ("r-plyr" ,r-plyr) | |
5172 | ("r-rcpp" ,r-rcpp) | |
5173 | ("r-reshape2" ,r-reshape2) | |
5174 | ("r-rsamtools" ,r-rsamtools) | |
5175 | ("r-s4vectors" ,r-s4vectors) | |
5176 | ("r-shiny" ,r-shiny) | |
5177 | ("r-shortread" ,r-shortread))) | |
5178 | (home-page "https://github.com/labbcb/Rqc") | |
5179 | (synopsis "Quality control tool for high-throughput sequencing data") | |
5180 | (description | |
5181 | "Rqc is an optimized tool designed for quality control and assessment of | |
5182 | high-throughput sequencing data. It performs parallel processing of entire | |
5183 | files and produces a report which contains a set of high-resolution | |
5184 | graphics.") | |
5185 | (license license:gpl2+))) | |
81e3de01 RW |
5186 | |
5187 | (define-public r-birewire | |
5188 | (package | |
5189 | (name "r-birewire") | |
a9e5145c | 5190 | (version "3.18.0") |
81e3de01 RW |
5191 | (source |
5192 | (origin | |
5193 | (method url-fetch) | |
5194 | (uri (bioconductor-uri "BiRewire" version)) | |
5195 | (sha256 | |
5196 | (base32 | |
a9e5145c | 5197 | "1074cp422ail72yajn8p0bg26h6zzz07nzypnwfyv86qrpvpdw9q")))) |
81e3de01 RW |
5198 | (properties `((upstream-name . "BiRewire"))) |
5199 | (build-system r-build-system) | |
5200 | (propagated-inputs | |
5201 | `(("r-igraph" ,r-igraph) | |
5202 | ("r-matrix" ,r-matrix) | |
5203 | ("r-slam" ,r-slam) | |
5204 | ("r-tsne" ,r-tsne))) | |
5205 | (home-page "https://bioconductor.org/packages/release/bioc/html/BiRewire.html") | |
5206 | (synopsis "Tools for randomization of bipartite graphs") | |
5207 | (description | |
5208 | "This package provides functions for bipartite network rewiring through N | |
5209 | consecutive switching steps and for the computation of the minimal number of | |
5210 | switching steps to be performed in order to maximise the dissimilarity with | |
5211 | respect to the original network. It includes functions for the analysis of | |
5212 | the introduced randomness across the switching steps and several other | |
5213 | routines to analyse the resulting networks and their natural projections.") | |
5214 | (license license:gpl3))) | |
1a24f855 RW |
5215 | |
5216 | (define-public r-birta | |
5217 | (package | |
5218 | (name "r-birta") | |
8d766270 | 5219 | (version "1.30.0") |
1a24f855 RW |
5220 | (source |
5221 | (origin | |
5222 | (method url-fetch) | |
5223 | (uri (bioconductor-uri "birta" version)) | |
5224 | (sha256 | |
5225 | (base32 | |
8d766270 | 5226 | "1zhlwapdgkz0fpv5bqfxh9aw6ymnmxnnm1r0n0kfzn5izyjavslg")))) |
1a24f855 RW |
5227 | (build-system r-build-system) |
5228 | (propagated-inputs | |
5229 | `(("r-biobase" ,r-biobase) | |
5230 | ("r-limma" ,r-limma) | |
5231 | ("r-mass" ,r-mass))) | |
5232 | (home-page "https://bioconductor.org/packages/birta") | |
5233 | (synopsis "Bayesian inference of regulation of transcriptional activity") | |
5234 | (description | |
5235 | "Expression levels of mRNA molecules are regulated by different | |
5236 | processes, comprising inhibition or activation by transcription factors and | |
5237 | post-transcriptional degradation by microRNAs. @dfn{birta} (Bayesian | |
5238 | Inference of Regulation of Transcriptional Activity) uses the regulatory | |
5239 | networks of transcription factors and miRNAs together with mRNA and miRNA | |
5240 | expression data to predict switches in regulatory activity between two | |
5241 | conditions. A Bayesian network is used to model the regulatory structure and | |
5242 | Markov-Chain-Monte-Carlo is applied to sample the activity states.") | |
5243 | (license license:gpl2+))) | |
a9fac3f4 | 5244 | |
b4a22cca RW |
5245 | (define-public r-multidataset |
5246 | (package | |
5247 | (name "r-multidataset") | |
5248 | (version "1.14.0") | |
5249 | (source | |
5250 | (origin | |
5251 | (method url-fetch) | |
5252 | (uri (bioconductor-uri "MultiDataSet" version)) | |
5253 | (sha256 | |
5254 | (base32 | |
5255 | "0iw99ymrv3ls023mpmgyagmb5simgsgadpj0k4bnssfaqnklywlj")))) | |
5256 | (properties `((upstream-name . "MultiDataSet"))) | |
5257 | (build-system r-build-system) | |
5258 | (propagated-inputs | |
5259 | `(("r-biobase" ,r-biobase) | |
5260 | ("r-biocgenerics" ,r-biocgenerics) | |
5261 | ("r-genomicranges" ,r-genomicranges) | |
5262 | ("r-ggplot2" ,r-ggplot2) | |
5263 | ("r-ggrepel" ,r-ggrepel) | |
5264 | ("r-iranges" ,r-iranges) | |
5265 | ("r-limma" ,r-limma) | |
5266 | ("r-qqman" ,r-qqman) | |
5267 | ("r-s4vectors" ,r-s4vectors) | |
5268 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
5269 | (home-page "https://bioconductor.org/packages/MultiDataSet/") | |
5270 | (synopsis "Implementation of MultiDataSet and ResultSet") | |
5271 | (description | |
5272 | "This package provides an implementation of the BRGE's (Bioinformatic | |
5273 | Research Group in Epidemiology from Center for Research in Environmental | |
5274 | Epidemiology) MultiDataSet and ResultSet. MultiDataSet is designed for | |
5275 | integrating multi omics data sets and ResultSet is a container for omics | |
5276 | results. This package contains base classes for MEAL and rexposome | |
5277 | packages.") | |
5278 | (license license:expat))) | |
5279 | ||
a9fac3f4 RW |
5280 | (define-public r-ropls |
5281 | (package | |
5282 | (name "r-ropls") | |
c5d75df3 | 5283 | (version "1.18.8") |
a9fac3f4 RW |
5284 | (source |
5285 | (origin | |
5286 | (method url-fetch) | |
5287 | (uri (bioconductor-uri "ropls" version)) | |
5288 | (sha256 | |
5289 | (base32 | |
c5d75df3 | 5290 | "033i39r4037nd54jnp5zdn1vpzh61r671vmq0sf8dqrfblhm4w7a")))) |
a9fac3f4 | 5291 | (build-system r-build-system) |
643aaf7e RW |
5292 | (propagated-inputs |
5293 | `(("r-biobase" ,r-biobase) | |
5294 | ("r-multidataset" ,r-multidataset))) | |
a9fac3f4 RW |
5295 | (native-inputs |
5296 | `(("r-knitr" ,r-knitr))) ; for vignettes | |
5297 | (home-page "https://dx.doi.org/10.1021/acs.jproteome.5b00354") | |
5298 | (synopsis "Multivariate analysis and feature selection of omics data") | |
5299 | (description | |
5300 | "Latent variable modeling with @dfn{Principal Component Analysis} (PCA) | |
5301 | and @dfn{Partial Least Squares} (PLS) are powerful methods for visualization, | |
5302 | regression, classification, and feature selection of omics data where the | |
5303 | number of variables exceeds the number of samples and with multicollinearity | |
5304 | among variables. @dfn{Orthogonal Partial Least Squares} (OPLS) enables to | |
5305 | separately model the variation correlated (predictive) to the factor of | |
5306 | interest and the uncorrelated (orthogonal) variation. While performing | |
5307 | similarly to PLS, OPLS facilitates interpretation. | |
5308 | ||
5309 | This package provides imlementations of PCA, PLS, and OPLS for multivariate | |
5310 | analysis and feature selection of omics data. In addition to scores, loadings | |
5311 | and weights plots, the package provides metrics and graphics to determine the | |
5312 | optimal number of components (e.g. with the R2 and Q2 coefficients), check the | |
5313 | validity of the model by permutation testing, detect outliers, and perform | |
5314 | feature selection (e.g. with Variable Importance in Projection or regression | |
5315 | coefficients).") | |
5316 | (license license:cecill))) | |
075a9094 RW |
5317 | |
5318 | (define-public r-biosigner | |
5319 | (package | |
5320 | (name "r-biosigner") | |
4bcb38c8 | 5321 | (version "1.14.4") |
075a9094 RW |
5322 | (source |
5323 | (origin | |
5324 | (method url-fetch) | |
5325 | (uri (bioconductor-uri "biosigner" version)) | |
5326 | (sha256 | |
5327 | (base32 | |
4bcb38c8 | 5328 | "0hypk784xcax99mp673md6kvx45chk2nxbqniww7zm9q2hj983hl")))) |
075a9094 RW |
5329 | (build-system r-build-system) |
5330 | (propagated-inputs | |
5331 | `(("r-biobase" ,r-biobase) | |
5332 | ("r-e1071" ,r-e1071) | |
7d29dc9c | 5333 | ("r-multidataset" ,r-multidataset) |
075a9094 RW |
5334 | ("r-randomforest" ,r-randomforest) |
5335 | ("r-ropls" ,r-ropls))) | |
5336 | (native-inputs | |
f7100eda | 5337 | `(("r-knitr" ,r-knitr))) |
075a9094 RW |
5338 | (home-page "https://bioconductor.org/packages/biosigner/") |
5339 | (synopsis "Signature discovery from omics data") | |
5340 | (description | |
5341 | "Feature selection is critical in omics data analysis to extract | |
5342 | restricted and meaningful molecular signatures from complex and high-dimension | |
5343 | data, and to build robust classifiers. This package implements a method to | |
5344 | assess the relevance of the variables for the prediction performances of the | |
5345 | classifier. The approach can be run in parallel with the PLS-DA, Random | |
5346 | Forest, and SVM binary classifiers. The signatures and the corresponding | |
5347 | 'restricted' models are returned, enabling future predictions on new | |
5348 | datasets.") | |
5349 | (license license:cecill))) | |
ae6fa185 RW |
5350 | |
5351 | (define-public r-annotatr | |
5352 | (package | |
5353 | (name "r-annotatr") | |
70007256 | 5354 | (version "1.12.1") |
ae6fa185 RW |
5355 | (source |
5356 | (origin | |
5357 | (method url-fetch) | |
5358 | (uri (bioconductor-uri "annotatr" version)) | |
5359 | (sha256 | |
5360 | (base32 | |
70007256 | 5361 | "1bibk3p1q4cavqy11xs6rqqhqdjsq2dd7lf7blwcr27s5ajcd6dj")))) |
ae6fa185 RW |
5362 | (build-system r-build-system) |
5363 | (propagated-inputs | |
5364 | `(("r-annotationdbi" ,r-annotationdbi) | |
5365 | ("r-annotationhub" ,r-annotationhub) | |
5366 | ("r-dplyr" ,r-dplyr) | |
5367 | ("r-genomeinfodb" ,r-genomeinfodb) | |
5368 | ("r-genomicfeatures" ,r-genomicfeatures) | |
5369 | ("r-genomicranges" ,r-genomicranges) | |
5370 | ("r-ggplot2" ,r-ggplot2) | |
5371 | ("r-iranges" ,r-iranges) | |
5372 | ("r-readr" ,r-readr) | |
5373 | ("r-regioner" ,r-regioner) | |
5374 | ("r-reshape2" ,r-reshape2) | |
5375 | ("r-rtracklayer" ,r-rtracklayer) | |
5376 | ("r-s4vectors" ,r-s4vectors))) | |
5377 | (home-page "https://bioconductor.org/packages/annotatr/") | |
5378 | (synopsis "Annotation of genomic regions to genomic annotations") | |
5379 | (description | |
5380 | "Given a set of genomic sites/regions (e.g. ChIP-seq peaks, CpGs, | |
5381 | differentially methylated CpGs or regions, SNPs, etc.) it is often of interest | |
5382 | to investigate the intersecting genomic annotations. Such annotations include | |
5383 | those relating to gene models (promoters, 5'UTRs, exons, introns, and 3'UTRs), | |
5384 | CpGs (CpG islands, CpG shores, CpG shelves), or regulatory sequences such as | |
5385 | enhancers. The annotatr package provides an easy way to summarize and | |
5386 | visualize the intersection of genomic sites/regions with genomic | |
5387 | annotations.") | |
5388 | (license license:gpl3))) | |
2cb738a6 RW |
5389 | |
5390 | (define-public r-rsubread | |
5391 | (package | |
5392 | (name "r-rsubread") | |
e01fa33b | 5393 | (version "2.0.1") |
2cb738a6 RW |
5394 | (source |
5395 | (origin | |
5396 | (method url-fetch) | |
5397 | (uri (bioconductor-uri "Rsubread" version)) | |
5398 | (sha256 | |
5399 | (base32 | |
e01fa33b | 5400 | "0pdkx9mhvzw3a4ff725qvda9bxvs9vh2ppb29cc5jrivgjndv5cy")))) |
2cb738a6 RW |
5401 | (properties `((upstream-name . "Rsubread"))) |
5402 | (build-system r-build-system) | |
5403 | (inputs `(("zlib" ,zlib))) | |
5404 | (home-page "https://bioconductor.org/packages/Rsubread/") | |
5405 | (synopsis "Subread sequence alignment and counting for R") | |
5406 | (description | |
5407 | "This package provides tools for alignment, quantification and analysis | |
5408 | of second and third generation sequencing data. It includes functionality for | |
5409 | read mapping, read counting, SNP calling, structural variant detection and | |
5410 | gene fusion discovery. It can be applied to all major sequencing techologies | |
5411 | and to both short and long sequence reads.") | |
5412 | (license license:gpl3))) | |
a6fedf1f | 5413 | |
a0422d18 | 5414 | (define-public r-flowutils |
5415 | (package | |
5416 | (name "r-flowutils") | |
482ba0b3 | 5417 | (version "1.50.0") |
a0422d18 | 5418 | (source |
5419 | (origin | |
5420 | (method url-fetch) | |
5421 | (uri (bioconductor-uri "flowUtils" version)) | |
5422 | (sha256 | |
5423 | (base32 | |
482ba0b3 | 5424 | "1xcs19j9p3izvksyy5wzsbicwby0dsa9g2w7gjzwynzgj5dpfr81")))) |
a0422d18 | 5425 | (properties `((upstream-name . "flowUtils"))) |
5426 | (build-system r-build-system) | |
5427 | (propagated-inputs | |
5428 | `(("r-biobase" ,r-biobase) | |
5429 | ("r-corpcor" ,r-corpcor) | |
5430 | ("r-flowcore" ,r-flowcore) | |
5431 | ("r-graph" ,r-graph) | |
5432 | ("r-runit" ,r-runit) | |
5433 | ("r-xml" ,r-xml))) | |
5434 | (home-page "https://github.com/jspidlen/flowUtils") | |
5435 | (synopsis "Utilities for flow cytometry") | |
5436 | (description | |
5437 | "This package provides utilities for flow cytometry data.") | |
5438 | (license license:artistic2.0))) | |
5439 | ||
ed6f49fc | 5440 | (define-public r-consensusclusterplus |
5441 | (package | |
5442 | (name "r-consensusclusterplus") | |
8ad6b23f | 5443 | (version "1.50.0") |
ed6f49fc | 5444 | (source |
5445 | (origin | |
5446 | (method url-fetch) | |
5447 | (uri (bioconductor-uri "ConsensusClusterPlus" version)) | |
5448 | (sha256 | |
5449 | (base32 | |
8ad6b23f | 5450 | "0pnh5zy6d3c364xxjdn5zp3kf5afhsxv6yzkdn1qspny0pmqlrp4")))) |
ed6f49fc | 5451 | (properties |
5452 | `((upstream-name . "ConsensusClusterPlus"))) | |
5453 | (build-system r-build-system) | |
5454 | (propagated-inputs | |
5455 | `(("r-all" ,r-all) | |
5456 | ("r-biobase" ,r-biobase) | |
5457 | ("r-cluster" ,r-cluster))) | |
5458 | (home-page "https://bioconductor.org/packages/ConsensusClusterPlus") | |
5459 | (synopsis "Clustering algorithm") | |
5460 | (description | |
5461 | "This package provides an implementation of an algorithm for determining | |
5462 | cluster count and membership by stability evidence in unsupervised analysis.") | |
5463 | (license license:gpl2))) | |
5464 | ||
b4aee31d RW |
5465 | (define-public r-cytolib |
5466 | (package | |
5467 | (name "r-cytolib") | |
5468 | (version "1.8.0") | |
5469 | (source | |
5470 | (origin | |
5471 | (method url-fetch) | |
5472 | (uri (bioconductor-uri "cytolib" version)) | |
5473 | (sha256 | |
5474 | (base32 | |
5475 | "1zk5i09k782lw6297gl3rh0g4fxswr2ang8dgqj7p0814l7h15k9")))) | |
5476 | (properties `((upstream-name . "cytolib"))) | |
5477 | (build-system r-build-system) | |
5478 | (home-page "https://bioconductor.org/packages/cytolib/") | |
5479 | (synopsis "C++ infrastructure for working with gated cytometry") | |
5480 | (description | |
5481 | "This package provides the core data structure and API to represent and | |
5482 | interact with gated cytometry data.") | |
5483 | (license license:artistic2.0))) | |
5484 | ||
a6fedf1f | 5485 | (define-public r-flowcore |
5486 | (package | |
5487 | (name "r-flowcore") | |
b2a2f321 | 5488 | (version "1.52.1") |
a6fedf1f | 5489 | (source |
5490 | (origin | |
5491 | (method url-fetch) | |
5492 | (uri (bioconductor-uri "flowCore" version)) | |
5493 | (sha256 | |
5494 | (base32 | |
b2a2f321 | 5495 | "08kvxc187iwlixibx1860jcp5g9bsw8abkv06x2qv1w83fas4pp2")))) |
a6fedf1f | 5496 | (properties `((upstream-name . "flowCore"))) |
5497 | (build-system r-build-system) | |
5498 | (propagated-inputs | |
5499 | `(("r-bh" ,r-bh) | |
5500 | ("r-biobase" ,r-biobase) | |
5501 | ("r-biocgenerics" ,r-biocgenerics) | |
b2a2f321 | 5502 | ("r-cytolib" ,r-cytolib) |
a6fedf1f | 5503 | ("r-matrixstats" ,r-matrixstats) |
b2a2f321 | 5504 | ("r-rcpp" ,r-rcpp))) |
a6fedf1f | 5505 | (home-page "https://bioconductor.org/packages/flowCore") |
5506 | (synopsis "Basic structures for flow cytometry data") | |
5507 | (description | |
5508 | "This package provides S4 data structures and basic functions to deal | |
5509 | with flow cytometry data.") | |
5510 | (license license:artistic2.0))) | |
e0cb053e | 5511 | |
5512 | (define-public r-flowmeans | |
5513 | (package | |
5514 | (name "r-flowmeans") | |
80420878 | 5515 | (version "1.46.0") |
e0cb053e | 5516 | (source |
5517 | (origin | |
5518 | (method url-fetch) | |
5519 | (uri (bioconductor-uri "flowMeans" version)) | |
5520 | (sha256 | |
5521 | (base32 | |
80420878 | 5522 | "1yisrikaafmpb4sig2c5l0wcz4idrs4as7i9x90v6z2v94iq0m8h")))) |
e0cb053e | 5523 | (properties `((upstream-name . "flowMeans"))) |
5524 | (build-system r-build-system) | |
5525 | (propagated-inputs | |
5526 | `(("r-biobase" ,r-biobase) | |
5527 | ("r-feature" ,r-feature) | |
5528 | ("r-flowcore" ,r-flowcore) | |
5529 | ("r-rrcov" ,r-rrcov))) | |
5530 | (home-page "https://bioconductor.org/packages/flowMeans") | |
5531 | (synopsis "Non-parametric flow cytometry data gating") | |
5532 | (description | |
5533 | "This package provides tools to identify cell populations in Flow | |
5534 | Cytometry data using non-parametric clustering and segmented-regression-based | |
5535 | change point detection.") | |
5536 | (license license:artistic2.0))) | |
1502751b | 5537 | |
15ac0c19 RW |
5538 | (define-public r-ncdfflow |
5539 | (package | |
5540 | (name "r-ncdfflow") | |
5541 | (version "2.32.0") | |
5542 | (source | |
5543 | (origin | |
5544 | (method url-fetch) | |
5545 | (uri (bioconductor-uri "ncdfFlow" version)) | |
5546 | (sha256 | |
5547 | (base32 | |
5548 | "06lscx6h4rg80ifi90rj7z2497b8w1fjipm3l8s3230rkizhh02i")))) | |
5549 | (properties `((upstream-name . "ncdfFlow"))) | |
5550 | (build-system r-build-system) | |
5551 | (inputs | |
5552 | `(("zlib" ,zlib))) | |
5553 | (propagated-inputs | |
5554 | `(("r-bh" ,r-bh) | |
5555 | ("r-biobase" ,r-biobase) | |
5556 | ("r-biocgenerics" ,r-biocgenerics) | |
5557 | ("r-flowcore" ,r-flowcore) | |
5558 | ("r-rcpp" ,r-rcpp) | |
5559 | ("r-rcpparmadillo" ,r-rcpparmadillo) | |
5560 | ("r-rhdf5lib" ,r-rhdf5lib) | |
5561 | ("r-zlibbioc" ,r-zlibbioc))) | |
5562 | (home-page "https://bioconductor.org/packages/ncdfFlow/") | |
5563 | (synopsis "HDF5 based storage for flow cytometry data") | |
5564 | (description | |
5565 | "This package provides HDF5 storage based methods and functions for | |
5566 | manipulation of flow cytometry data.") | |
5567 | (license license:artistic2.0))) | |
5568 | ||
f5f44031 RW |
5569 | (define-public r-ggcyto |
5570 | (package | |
5571 | (name "r-ggcyto") | |
0754fefb | 5572 | (version "1.14.1") |
f5f44031 RW |
5573 | (source |
5574 | (origin | |
5575 | (method url-fetch) | |
5576 | (uri (bioconductor-uri "ggcyto" version)) | |
5577 | (sha256 | |
5578 | (base32 | |
0754fefb | 5579 | "16jwdslhmj1nsa28wmaircy15cq7qn8nsyiawinjv711qiqhgw50")))) |
f5f44031 RW |
5580 | (properties `((upstream-name . "ggcyto"))) |
5581 | (build-system r-build-system) | |
5582 | (propagated-inputs | |
5583 | `(("r-data-table" ,r-data-table) | |
5584 | ("r-flowcore" ,r-flowcore) | |
5585 | ("r-flowworkspace" ,r-flowworkspace) | |
5586 | ("r-ggplot2" ,r-ggplot2) | |
5587 | ("r-gridextra" ,r-gridextra) | |
5588 | ("r-ncdfflow" ,r-ncdfflow) | |
5589 | ("r-plyr" ,r-plyr) | |
5590 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5591 | ("r-rlang" ,r-rlang) | |
5592 | ("r-scales" ,r-scales))) | |
0754fefb RW |
5593 | (native-inputs |
5594 | `(("r-knitr" ,r-knitr))) | |
f5f44031 RW |
5595 | (home-page "https://github.com/RGLab/ggcyto/issues") |
5596 | (synopsis "Visualize Cytometry data with ggplot") | |
5597 | (description | |
5598 | "With the dedicated fortify method implemented for @code{flowSet}, | |
5599 | @code{ncdfFlowSet} and @code{GatingSet} classes, both raw and gated flow | |
5600 | cytometry data can be plotted directly with ggplot. The @code{ggcyto} wrapper | |
5601 | and some custom layers also make it easy to add gates and population | |
5602 | statistics to the plot.") | |
5603 | (license license:artistic2.0))) | |
5604 | ||
0dd4b7d7 RW |
5605 | (define-public r-flowviz |
5606 | (package | |
5607 | (name "r-flowviz") | |
5608 | (version "1.50.0") | |
5609 | (source | |
5610 | (origin | |
5611 | (method url-fetch) | |
5612 | (uri (bioconductor-uri "flowViz" version)) | |
5613 | (sha256 | |
5614 | (base32 | |
5615 | "0ik16bxcfcg3q26ra3055718kskid64aaazcbqsxalca9ppdm4k7")))) | |
5616 | (properties `((upstream-name . "flowViz"))) | |
5617 | (build-system r-build-system) | |
5618 | (propagated-inputs | |
5619 | `(("r-biobase" ,r-biobase) | |
5620 | ("r-flowcore" ,r-flowcore) | |
5621 | ("r-hexbin" ,r-hexbin) | |
5622 | ("r-idpmisc" ,r-idpmisc) | |
5623 | ("r-kernsmooth" ,r-kernsmooth) | |
5624 | ("r-lattice" ,r-lattice) | |
5625 | ("r-latticeextra" ,r-latticeextra) | |
5626 | ("r-mass" ,r-mass) | |
5627 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
5628 | (home-page "https://bioconductor.org/packages/flowViz/") | |
5629 | (synopsis "Visualization for flow cytometry") | |
5630 | (description | |
5631 | "This package provides visualization tools for flow cytometry data.") | |
5632 | (license license:artistic2.0))) | |
5633 | ||
c8ab9eb1 RW |
5634 | (define-public r-flowclust |
5635 | (package | |
5636 | (name "r-flowclust") | |
5637 | (version "3.24.0") | |
5638 | (source | |
5639 | (origin | |
5640 | (method url-fetch) | |
5641 | (uri (bioconductor-uri "flowClust" version)) | |
5642 | (sha256 | |
5643 | (base32 | |
5644 | "0k4bgc4mf512njfdfg5ld9l7slgfxyfh766jab87j96zrrgcnj8s")))) | |
5645 | (properties `((upstream-name . "flowClust"))) | |
5646 | (build-system r-build-system) | |
5647 | (arguments | |
5648 | `(#:configure-flags | |
5649 | (list "--configure-args=--enable-bundled-gsl=no"))) | |
5650 | (propagated-inputs | |
5651 | `(("r-biobase" ,r-biobase) | |
5652 | ("r-biocgenerics" ,r-biocgenerics) | |
5653 | ("r-clue" ,r-clue) | |
5654 | ("r-corpcor" ,r-corpcor) | |
5655 | ("r-ellipse" ,r-ellipse) | |
5656 | ("r-flowcore" ,r-flowcore) | |
5657 | ("r-flowviz" ,r-flowviz) | |
5658 | ("r-graph" ,r-graph) | |
5659 | ("r-mnormt" ,r-mnormt))) | |
5660 | (inputs | |
5661 | `(("gsl" ,gsl))) | |
5662 | (native-inputs | |
5663 | `(("pkg-config" ,pkg-config))) | |
5664 | (home-page "https://bioconductor.org/packages/flowClust") | |
5665 | (synopsis "Clustering for flow cytometry") | |
5666 | (description | |
5667 | "This package provides robust model-based clustering using a t-mixture | |
5668 | model with Box-Cox transformation.") | |
5669 | (license license:artistic2.0))) | |
5670 | ||
f1964519 RW |
5671 | ;; TODO: this package bundles an old version of protobuf. It's not easy to |
5672 | ;; make it use our protobuf package instead. | |
5673 | (define-public r-rprotobuflib | |
5674 | (package | |
5675 | (name "r-rprotobuflib") | |
5676 | (version "1.8.0") | |
5677 | (source | |
5678 | (origin | |
5679 | (method url-fetch) | |
5680 | (uri (bioconductor-uri "RProtoBufLib" version)) | |
5681 | (sha256 | |
5682 | (base32 | |
5683 | "0dlgki21a37bxqh3cf83vl5zqxm86472g8a9plvhrjzzsn3mwnrm")))) | |
5684 | (properties `((upstream-name . "RProtoBufLib"))) | |
5685 | (build-system r-build-system) | |
5686 | (arguments | |
5687 | `(#:phases | |
5688 | (modify-phases %standard-phases | |
5689 | (add-after 'unpack 'unpack-bundled-sources | |
5690 | (lambda _ | |
5691 | (with-directory-excursion "src" | |
5692 | (invoke "tar" "xf" "protobuf-2.6.0.tgz")) | |
5693 | #t))))) | |
5694 | (home-page "https://bioconductor.org/packages/RProtoBufLib/") | |
5695 | (synopsis "C++ headers and static libraries of Protocol buffers") | |
5696 | (description | |
5697 | "This package provides the headers and static library of Protocol buffers | |
5698 | for other R packages to compile and link against.") | |
5699 | (license license:bsd-3))) | |
5700 | ||
82c11117 RW |
5701 | (define-public r-flowworkspace |
5702 | (package | |
5703 | (name "r-flowworkspace") | |
e8ccb98a | 5704 | (version "3.34.1") |
82c11117 RW |
5705 | (source |
5706 | (origin | |
5707 | (method url-fetch) | |
5708 | (uri (bioconductor-uri "flowWorkspace" version)) | |
5709 | (sha256 | |
5710 | (base32 | |
e8ccb98a | 5711 | "1ijbc6z9ljhrw3cqr02smgplhrfg44gzrb1dq4gbrpq3nj4khhpn")))) |
82c11117 RW |
5712 | (properties `((upstream-name . "flowWorkspace"))) |
5713 | (build-system r-build-system) | |
5714 | (propagated-inputs | |
5715 | `(("r-bh" ,r-bh) | |
5716 | ("r-biobase" ,r-biobase) | |
5717 | ("r-biocgenerics" ,r-biocgenerics) | |
5718 | ("r-cytolib" ,r-cytolib) | |
5719 | ("r-data-table" ,r-data-table) | |
5720 | ("r-digest" ,r-digest) | |
5721 | ("r-dplyr" ,r-dplyr) | |
5722 | ("r-flowcore" ,r-flowcore) | |
5723 | ("r-flowviz" ,r-flowviz) | |
5724 | ("r-graph" ,r-graph) | |
5725 | ("r-gridextra" ,r-gridextra) | |
5726 | ("r-lattice" ,r-lattice) | |
5727 | ("r-latticeextra" ,r-latticeextra) | |
5728 | ("r-matrixstats" ,r-matrixstats) | |
5729 | ("r-ncdfflow" ,r-ncdfflow) | |
5730 | ("r-rbgl" ,r-rbgl) | |
5731 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5732 | ("r-rcpp" ,r-rcpp) | |
5733 | ("r-rcppparallel" ,r-rcppparallel) | |
5734 | ("r-rgraphviz" ,r-rgraphviz) | |
5735 | ("r-rprotobuflib" ,r-rprotobuflib) | |
5736 | ("r-scales" ,r-scales) | |
5737 | ("r-stringr" ,r-stringr))) | |
5738 | (home-page "https://bioconductor.org/packages/flowWorkspace/") | |
5739 | (synopsis "Infrastructure for working with cytometry data") | |
5740 | (description | |
5741 | "This package is designed to facilitate comparison of automated gating | |
5742 | methods against manual gating done in flowJo. This package allows you to | |
5743 | import basic flowJo workspaces into BioConductor and replicate the gating from | |
5744 | flowJo using the @code{flowCore} functionality. Gating hierarchies, groups of | |
5745 | samples, compensation, and transformation are performed so that the output | |
5746 | matches the flowJo analysis.") | |
5747 | (license license:artistic2.0))) | |
5748 | ||
b700b9ec RW |
5749 | (define-public r-flowstats |
5750 | (package | |
5751 | (name "r-flowstats") | |
5752 | (version "3.44.0") | |
5753 | (source | |
5754 | (origin | |
5755 | (method url-fetch) | |
5756 | (uri (bioconductor-uri "flowStats" version)) | |
5757 | (sha256 | |
5758 | (base32 | |
5759 | "0pql0lpf90nra7w6z6nd8l9cgjlsg2pxysfravnbzfhl3pjvd96w")))) | |
5760 | (properties `((upstream-name . "flowStats"))) | |
5761 | (build-system r-build-system) | |
5762 | (propagated-inputs | |
5763 | `(("r-biobase" ,r-biobase) | |
5764 | ("r-biocgenerics" ,r-biocgenerics) | |
5765 | ("r-cluster" ,r-cluster) | |
5766 | ("r-fda" ,r-fda) | |
5767 | ("r-flowcore" ,r-flowcore) | |
5768 | ("r-flowviz" ,r-flowviz) | |
5769 | ("r-flowworkspace" ,r-flowworkspace) | |
5770 | ("r-kernsmooth" ,r-kernsmooth) | |
5771 | ("r-ks" ,r-ks) | |
5772 | ("r-lattice" ,r-lattice) | |
5773 | ("r-mass" ,r-mass) | |
5774 | ("r-ncdfflow" ,r-ncdfflow) | |
5775 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5776 | ("r-rrcov" ,r-rrcov))) | |
5777 | (home-page "http://www.github.com/RGLab/flowStats") | |
5778 | (synopsis "Statistical methods for the analysis of flow cytometry data") | |
5779 | (description | |
5780 | "This package provides methods and functionality to analyze flow data | |
5781 | that is beyond the basic infrastructure provided by the @code{flowCore} | |
5782 | package.") | |
5783 | (license license:artistic2.0))) | |
5784 | ||
6aedc805 RW |
5785 | (define-public r-opencyto |
5786 | (package | |
5787 | (name "r-opencyto") | |
5788 | (version "1.24.0") | |
5789 | (source | |
5790 | (origin | |
5791 | (method url-fetch) | |
5792 | (uri (bioconductor-uri "openCyto" version)) | |
5793 | (sha256 | |
5794 | (base32 | |
5795 | "0h25nhvq1zq624wsgb55wjcgri9rcd2fnqkb31h9jdakr01dw2sb")))) | |
5796 | (properties `((upstream-name . "openCyto"))) | |
5797 | (build-system r-build-system) | |
5798 | (propagated-inputs | |
5799 | `(("r-biobase" ,r-biobase) | |
5800 | ("r-biocgenerics" ,r-biocgenerics) | |
5801 | ("r-clue" ,r-clue) | |
5802 | ("r-data-table" ,r-data-table) | |
5803 | ("r-flowclust" ,r-flowclust) | |
5804 | ("r-flowcore" ,r-flowcore) | |
5805 | ("r-flowstats" ,r-flowstats) | |
5806 | ("r-flowviz" ,r-flowviz) | |
5807 | ("r-flowworkspace" ,r-flowworkspace) | |
5808 | ("r-graph" ,r-graph) | |
5809 | ("r-gtools" ,r-gtools) | |
5810 | ("r-ks" ,r-ks) | |
5811 | ("r-lattice" ,r-lattice) | |
5812 | ("r-mass" ,r-mass) | |
5813 | ("r-ncdfflow" ,r-ncdfflow) | |
5814 | ("r-plyr" ,r-plyr) | |
5815 | ("r-r-utils" ,r-r-utils) | |
5816 | ("r-rbgl" ,r-rbgl) | |
5817 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5818 | ("r-rcpp" ,r-rcpp) | |
5819 | ("r-rrcov" ,r-rrcov))) | |
5820 | (home-page "https://bioconductor.org/packages/openCyto") | |
5821 | (synopsis "Hierarchical gating pipeline for flow cytometry data") | |
5822 | (description | |
5823 | "This package is designed to facilitate the automated gating methods in a | |
5824 | sequential way to mimic the manual gating strategy.") | |
5825 | (license license:artistic2.0))) | |
5826 | ||
7a62d5e0 RW |
5827 | (define-public r-cytoml |
5828 | (package | |
5829 | (name "r-cytoml") | |
5830 | (version "1.12.0") | |
5831 | (source | |
5832 | (origin | |
5833 | (method url-fetch) | |
5834 | (uri (bioconductor-uri "CytoML" version)) | |
5835 | (sha256 | |
5836 | (base32 | |
5837 | "0m8x18wkvis85cawv7j07pk59w76wnzy93ia99gd24j82z4h97p1")))) | |
5838 | (properties `((upstream-name . "CytoML"))) | |
5839 | (build-system r-build-system) | |
5840 | (inputs | |
5841 | `(("libxml2" ,libxml2))) | |
5842 | (propagated-inputs | |
5843 | `(("r-base64enc" ,r-base64enc) | |
5844 | ("r-bh" ,r-bh) | |
5845 | ("r-biobase" ,r-biobase) | |
5846 | ("r-corpcor" ,r-corpcor) | |
5847 | ("r-cytolib" ,r-cytolib) | |
5848 | ("r-data-table" ,r-data-table) | |
5849 | ("r-dplyr" ,r-dplyr) | |
5850 | ("r-flowcore" ,r-flowcore) | |
5851 | ("r-flowworkspace" ,r-flowworkspace) | |
5852 | ("r-ggcyto" ,r-ggcyto) | |
5853 | ("r-graph" ,r-graph) | |
5854 | ("r-jsonlite" ,r-jsonlite) | |
5855 | ("r-lattice" ,r-lattice) | |
5856 | ("r-ncdfflow" ,r-ncdfflow) | |
5857 | ("r-opencyto" ,r-opencyto) | |
5858 | ("r-plyr" ,r-plyr) | |
5859 | ("r-rbgl" ,r-rbgl) | |
5860 | ("r-rcpp" ,r-rcpp) | |
5861 | ("r-rcppparallel" ,r-rcppparallel) | |
5862 | ("r-rgraphviz" ,r-rgraphviz) | |
5863 | ("r-rprotobuflib" ,r-rprotobuflib) | |
5864 | ("r-runit" ,r-runit) | |
5865 | ("r-xml" ,r-xml) | |
5866 | ("r-yaml" ,r-yaml))) | |
5867 | (home-page "https://github.com/RGLab/CytoML") | |
5868 | (synopsis "GatingML interface for cross platform cytometry data sharing") | |
5869 | (description | |
5870 | "This package provides an interface to implementations of the GatingML2.0 | |
5871 | standard to exchange gated cytometry data with other software platforms.") | |
5872 | (license license:artistic2.0))) | |
5873 | ||
1502751b | 5874 | (define-public r-flowsom |
5875 | (package | |
5876 | (name "r-flowsom") | |
ba71567a | 5877 | (version "1.18.0") |
1502751b | 5878 | (source |
5879 | (origin | |
5880 | (method url-fetch) | |
5881 | (uri (bioconductor-uri "FlowSOM" version)) | |
5882 | (sha256 | |
5883 | (base32 | |
ba71567a | 5884 | "0265sq4zvj6d6h5ghqj9xzm4b0z9v65kgyl88cgdcpdkzfnfcvd5")))) |
1502751b | 5885 | (properties `((upstream-name . "FlowSOM"))) |
5886 | (build-system r-build-system) | |
5887 | (propagated-inputs | |
5888 | `(("r-biocgenerics" ,r-biocgenerics) | |
5889 | ("r-consensusclusterplus" ,r-consensusclusterplus) | |
ba71567a | 5890 | ("r-cytoml" ,r-cytoml) |
1502751b | 5891 | ("r-flowcore" ,r-flowcore) |
ba71567a | 5892 | ("r-flowworkspace" ,r-flowworkspace) |
1502751b | 5893 | ("r-igraph" ,r-igraph) |
ba71567a | 5894 | ("r-rcolorbrewer" ,r-rcolorbrewer) |
1502751b | 5895 | ("r-tsne" ,r-tsne) |
5896 | ("r-xml" ,r-xml))) | |
5897 | (home-page "https://bioconductor.org/packages/FlowSOM/") | |
5898 | (synopsis "Visualize and interpret cytometry data") | |
5899 | (description | |
5900 | "FlowSOM offers visualization options for cytometry data, by using | |
5901 | self-organizing map clustering and minimal spanning trees.") | |
5902 | (license license:gpl2+))) | |
1adb9cbc | 5903 | |
5904 | (define-public r-mixomics | |
5905 | (package | |
5906 | (name "r-mixomics") | |
f607098f | 5907 | (version "6.10.8") |
1adb9cbc | 5908 | (source |
5909 | (origin | |
5910 | (method url-fetch) | |
5911 | (uri (bioconductor-uri "mixOmics" version)) | |
5912 | (sha256 | |
5913 | (base32 | |
f607098f | 5914 | "0307vhx9ck24rxqbvq15815ssxcc226sl2la060n204b51wi9jaa")))) |
1adb9cbc | 5915 | (properties `((upstream-name . "mixOmics"))) |
5916 | (build-system r-build-system) | |
5917 | (propagated-inputs | |
5918 | `(("r-corpcor" ,r-corpcor) | |
5919 | ("r-dplyr" ,r-dplyr) | |
5920 | ("r-ellipse" ,r-ellipse) | |
5921 | ("r-ggplot2" ,r-ggplot2) | |
5922 | ("r-gridextra" ,r-gridextra) | |
5923 | ("r-igraph" ,r-igraph) | |
5924 | ("r-lattice" ,r-lattice) | |
5925 | ("r-mass" ,r-mass) | |
5926 | ("r-matrixstats" ,r-matrixstats) | |
5927 | ("r-rarpack" ,r-rarpack) | |
5928 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5929 | ("r-reshape2" ,r-reshape2) | |
5930 | ("r-tidyr" ,r-tidyr))) | |
5931 | (home-page "http://www.mixOmics.org") | |
5932 | (synopsis "Multivariate methods for exploration of biological datasets") | |
5933 | (description | |
5934 | "mixOmics offers a wide range of multivariate methods for the exploration | |
5935 | and integration of biological datasets with a particular focus on variable | |
5936 | selection. The package proposes several sparse multivariate models we have | |
5937 | developed to identify the key variables that are highly correlated, and/or | |
5938 | explain the biological outcome of interest. The data that can be analysed | |
5939 | with mixOmics may come from high throughput sequencing technologies, such as | |
5940 | omics data (transcriptomics, metabolomics, proteomics, metagenomics etc) but | |
5941 | also beyond the realm of omics (e.g. spectral imaging). The methods | |
5942 | implemented in mixOmics can also handle missing values without having to | |
5943 | delete entire rows with missing data.") | |
5944 | (license license:gpl2+))) | |
a0efa069 | 5945 | |
5946 | (define-public r-depecher | |
5947 | (package | |
5948 | (name "r-depecher") | |
bf3722f9 | 5949 | (version "1.2.2") |
a0efa069 | 5950 | (source |
5951 | (origin | |
5952 | (method url-fetch) | |
5953 | (uri (bioconductor-uri "DepecheR" version)) | |
5954 | (sha256 | |
5955 | (base32 | |
bf3722f9 | 5956 | "199j2kw0xnw7y4v1gakm2jgyc7zzlj8xh0570f2yjq55gp1kggbm")))) |
a0efa069 | 5957 | (properties `((upstream-name . "DepecheR"))) |
5958 | (build-system r-build-system) | |
a0efa069 | 5959 | (propagated-inputs |
5960 | `(("r-beanplot" ,r-beanplot) | |
a0efa069 | 5961 | ("r-dosnow" ,r-dosnow) |
5962 | ("r-dplyr" ,r-dplyr) | |
2c8433ca | 5963 | ("r-fnn" ,r-fnn) |
a0efa069 | 5964 | ("r-foreach" ,r-foreach) |
5965 | ("r-ggplot2" ,r-ggplot2) | |
5966 | ("r-gplots" ,r-gplots) | |
5967 | ("r-mass" ,r-mass) | |
5968 | ("r-matrixstats" ,r-matrixstats) | |
5969 | ("r-mixomics" ,r-mixomics) | |
5970 | ("r-moments" ,r-moments) | |
5971 | ("r-rcpp" ,r-rcpp) | |
5972 | ("r-rcppeigen" ,r-rcppeigen) | |
5973 | ("r-reshape2" ,r-reshape2) | |
2c8433ca | 5974 | ("r-robustbase" ,r-robustbase) |
a0efa069 | 5975 | ("r-viridis" ,r-viridis))) |
bf3722f9 RW |
5976 | (native-inputs |
5977 | `(("r-knitr" ,r-knitr))) | |
a0efa069 | 5978 | (home-page "https://bioconductor.org/packages/DepecheR/") |
5979 | (synopsis "Identify traits of clusters in high-dimensional entities") | |
5980 | (description | |
5981 | "The purpose of this package is to identify traits in a dataset that can | |
5982 | separate groups. This is done on two levels. First, clustering is performed, | |
5983 | using an implementation of sparse K-means. Secondly, the generated clusters | |
5984 | are used to predict outcomes of groups of individuals based on their | |
5985 | distribution of observations in the different clusters. As certain clusters | |
5986 | with separating information will be identified, and these clusters are defined | |
5987 | by a sparse number of variables, this method can reduce the complexity of | |
5988 | data, to only emphasize the data that actually matters.") | |
5989 | (license license:expat))) | |
b46a0ee7 | 5990 | |
bb88417f RW |
5991 | (define-public r-rcistarget |
5992 | (package | |
5993 | (name "r-rcistarget") | |
51ffac45 | 5994 | (version "1.6.0") |
bb88417f RW |
5995 | (source |
5996 | (origin | |
5997 | (method url-fetch) | |
5998 | (uri (bioconductor-uri "RcisTarget" version)) | |
5999 | (sha256 | |
6000 | (base32 | |
51ffac45 | 6001 | "1nnah7s0jd24fpfyxsf76jas8dm23c3266aps124wdlqsp9q5qjw")))) |
bb88417f RW |
6002 | (properties `((upstream-name . "RcisTarget"))) |
6003 | (build-system r-build-system) | |
6004 | (propagated-inputs | |
6005 | `(("r-aucell" ,r-aucell) | |
6006 | ("r-biocgenerics" ,r-biocgenerics) | |
6007 | ("r-data-table" ,r-data-table) | |
6008 | ("r-feather" ,r-feather) | |
6009 | ("r-gseabase" ,r-gseabase) | |
6010 | ("r-r-utils" ,r-r-utils) | |
6011 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
6012 | (home-page "https://aertslab.org/#scenic") | |
6013 | (synopsis "Identify transcription factor binding motifs enriched on a gene list") | |
6014 | (description | |
6015 | "RcisTarget identifies @dfn{transcription factor binding motifs} (TFBS) | |
6016 | over-represented on a gene list. In a first step, RcisTarget selects DNA | |
6017 | motifs that are significantly over-represented in the surroundings of the | |
6018 | @dfn{transcription start site} (TSS) of the genes in the gene-set. This is | |
6019 | achieved by using a database that contains genome-wide cross-species rankings | |
6020 | for each motif. The motifs that are then annotated to TFs and those that have | |
6021 | a high @dfn{Normalized Enrichment Score} (NES) are retained. Finally, for | |
6022 | each motif and gene-set, RcisTarget predicts the candidate target genes (i.e. | |
6023 | genes in the gene-set that are ranked above the leading edge).") | |
6024 | (license license:gpl3))) | |
6025 | ||
b46a0ee7 RW |
6026 | (define-public r-cicero |
6027 | (package | |
6028 | (name "r-cicero") | |
6bd6097e | 6029 | (version "1.4.4") |
b46a0ee7 RW |
6030 | (source |
6031 | (origin | |
6032 | (method url-fetch) | |
6033 | (uri (bioconductor-uri "cicero" version)) | |
6034 | (sha256 | |
6035 | (base32 | |
6bd6097e | 6036 | "1ay1g2r0la4grcp1y8vcp211lfwzjf7j819ajzdirsh5dab8whld")))) |
b46a0ee7 RW |
6037 | (build-system r-build-system) |
6038 | (propagated-inputs | |
6039 | `(("r-assertthat" ,r-assertthat) | |
6040 | ("r-biobase" ,r-biobase) | |
6041 | ("r-biocgenerics" ,r-biocgenerics) | |
6042 | ("r-data-table" ,r-data-table) | |
6043 | ("r-dplyr" ,r-dplyr) | |
6044 | ("r-fnn" ,r-fnn) | |
6045 | ("r-genomicranges" ,r-genomicranges) | |
6046 | ("r-ggplot2" ,r-ggplot2) | |
6047 | ("r-glasso" ,r-glasso) | |
6048 | ("r-gviz" ,r-gviz) | |
6049 | ("r-igraph" ,r-igraph) | |
6050 | ("r-iranges" ,r-iranges) | |
6051 | ("r-matrix" ,r-matrix) | |
6052 | ("r-monocle" ,r-monocle) | |
6053 | ("r-plyr" ,r-plyr) | |
6054 | ("r-reshape2" ,r-reshape2) | |
6055 | ("r-s4vectors" ,r-s4vectors) | |
6056 | ("r-stringr" ,r-stringr) | |
6057 | ("r-tibble" ,r-tibble) | |
5ea4f604 | 6058 | ("r-tidyr" ,r-tidyr) |
b46a0ee7 | 6059 | ("r-vgam" ,r-vgam))) |
6bd6097e RW |
6060 | (native-inputs |
6061 | `(("r-knitr" ,r-knitr))) | |
b46a0ee7 RW |
6062 | (home-page "https://bioconductor.org/packages/cicero/") |
6063 | (synopsis "Predict cis-co-accessibility from single-cell data") | |
6064 | (description | |
6065 | "Cicero computes putative cis-regulatory maps from single-cell chromatin | |
6066 | accessibility data. It also extends the monocle package for use in chromatin | |
6067 | accessibility data.") | |
6068 | (license license:expat))) | |
14bb1c48 RW |
6069 | |
6070 | ;; This is the latest commit on the "monocle3" branch. | |
6071 | (define-public r-cicero-monocle3 | |
6072 | (let ((commit "fa2fb6515857a8cfc88bc9af044f34de1bcd2b7b") | |
6073 | (revision "1")) | |
6074 | (package (inherit r-cicero) | |
6075 | (name "r-cicero-monocle3") | |
6076 | (version (git-version "1.3.2" revision commit)) | |
6077 | (source | |
6078 | (origin | |
6079 | (method git-fetch) | |
6080 | (uri (git-reference | |
6081 | (url "https://github.com/cole-trapnell-lab/cicero-release.git") | |
6082 | (commit commit))) | |
6083 | (file-name (git-file-name name version)) | |
6084 | (sha256 | |
6085 | (base32 | |
6086 | "077yza93wdhi08n40md20jwk55k9lw1f3y0063qkk90cpz60wi0c")))) | |
6087 | (propagated-inputs | |
6088 | `(("r-monocle3" ,r-monocle3) | |
6089 | ,@(alist-delete "r-monocle" | |
6090 | (package-propagated-inputs r-cicero))))))) | |
a9815a6c RW |
6091 | |
6092 | (define-public r-cistopic | |
6093 | (let ((commit "29abd8df9afb60ff27ac3f0a590930debe926950") | |
6094 | (revision "0")) | |
6095 | (package | |
6096 | (name "r-cistopic") | |
6097 | (version (git-version "0.2.1" revision commit)) | |
6098 | (source | |
6099 | (origin | |
6100 | (method git-fetch) | |
6101 | (uri (git-reference | |
6102 | (url "https://github.com/aertslab/cisTopic.git") | |
6103 | (commit commit))) | |
6104 | (file-name (git-file-name name version)) | |
6105 | (sha256 | |
6106 | (base32 | |
6107 | "0s8irpsv5d2zcv4ihanvsf1vrpignzliscxnvs4519af3jmx78h8")))) | |
6108 | (build-system r-build-system) | |
6109 | (propagated-inputs | |
6110 | `(("r-aucell" ,r-aucell) | |
6111 | ("r-data-table" ,r-data-table) | |
6112 | ("r-dplyr" ,r-dplyr) | |
6113 | ("r-dosnow" ,r-dosnow) | |
6114 | ("r-dt" ,r-dt) | |
6115 | ("r-feather" ,r-feather) | |
6116 | ("r-fitdistrplus" ,r-fitdistrplus) | |
6117 | ("r-genomicranges" ,r-genomicranges) | |
6118 | ("r-ggplot2" ,r-ggplot2) | |
6119 | ("r-lda" ,r-lda) | |
6120 | ("r-matrix" ,r-matrix) | |
6121 | ("r-plyr" ,r-plyr) | |
6122 | ("r-rcistarget" ,r-rcistarget) | |
6123 | ("r-rtracklayer" ,r-rtracklayer) | |
6124 | ("r-s4vectors" ,r-s4vectors))) | |
6125 | (home-page "https://github.com/aertslab/cisTopic") | |
6126 | (synopsis "Modelling of cis-regulatory topics from single cell epigenomics data") | |
6127 | (description | |
6128 | "The sparse nature of single cell epigenomics data can be overruled using | |
6129 | probabilistic modelling methods such as @dfn{Latent Dirichlet | |
6130 | Allocation} (LDA). This package allows the probabilistic modelling of | |
6131 | cis-regulatory topics (cisTopics) from single cell epigenomics data, and | |
6132 | includes functionalities to identify cell states based on the contribution of | |
6133 | cisTopics and explore the nature and regulatory proteins driving them.") | |
6134 | (license license:gpl3)))) | |
d85c0f98 RW |
6135 | |
6136 | (define-public r-genie3 | |
6137 | (package | |
6138 | (name "r-genie3") | |
33ce50e3 | 6139 | (version "1.8.0") |
d85c0f98 RW |
6140 | (source |
6141 | (origin | |
6142 | (method url-fetch) | |
6143 | (uri (bioconductor-uri "GENIE3" version)) | |
6144 | (sha256 | |
6145 | (base32 | |
33ce50e3 | 6146 | "0p67lhgy3lb4nc958s51hx7rvgwhzwfic9xhpsrask40k43spv7l")))) |
d85c0f98 RW |
6147 | (properties `((upstream-name . "GENIE3"))) |
6148 | (build-system r-build-system) | |
6149 | (propagated-inputs `(("r-reshape2" ,r-reshape2))) | |
6150 | (home-page "https://bioconductor.org/packages/GENIE3") | |
6151 | (synopsis "Gene network inference with ensemble of trees") | |
6152 | (description | |
6153 | "This package implements the GENIE3 algorithm for inferring gene | |
6154 | regulatory networks from expression data.") | |
6155 | (license license:gpl2+))) | |
db316d73 RW |
6156 | |
6157 | (define-public r-roc | |
6158 | (package | |
6159 | (name "r-roc") | |
3672b74f | 6160 | (version "1.62.0") |
db316d73 RW |
6161 | (source |
6162 | (origin | |
6163 | (method url-fetch) | |
6164 | (uri (bioconductor-uri "ROC" version)) | |
6165 | (sha256 | |
6166 | (base32 | |
3672b74f | 6167 | "1aqpyc28czagg3nbybh55vf152nbar61jjw79w04326d97mc3j3y")))) |
db316d73 RW |
6168 | (properties `((upstream-name . "ROC"))) |
6169 | (build-system r-build-system) | |
3672b74f RW |
6170 | (propagated-inputs |
6171 | `(("r-knitr" ,r-knitr))) | |
db316d73 RW |
6172 | (home-page "https://www.bioconductor.org/packages/ROC/") |
6173 | (synopsis "Utilities for ROC curves") | |
6174 | (description | |
6175 | "This package provides utilities for @dfn{Receiver Operating | |
6176 | Characteristic} (ROC) curves, with a focus on micro arrays.") | |
6177 | (license license:artistic2.0))) | |
46721dea RW |
6178 | |
6179 | (define-public r-illuminahumanmethylation450kanno-ilmn12-hg19 | |
6180 | (package | |
6181 | (name "r-illuminahumanmethylation450kanno-ilmn12-hg19") | |
6182 | (version "0.6.0") | |
6183 | (source | |
6184 | (origin | |
6185 | (method url-fetch) | |
6186 | (uri (bioconductor-uri | |
6187 | "IlluminaHumanMethylation450kanno.ilmn12.hg19" | |
6188 | version 'annotation)) | |
6189 | (sha256 | |
6190 | (base32 | |
6191 | "059vlxsx3p3fcnywwirahsc6mlk813zpqnbv0jsrag6x5bb8z6r4")))) | |
6192 | (properties | |
6193 | `((upstream-name | |
6194 | . "IlluminaHumanMethylation450kanno.ilmn12.hg19"))) | |
6195 | (build-system r-build-system) | |
6196 | (propagated-inputs `(("r-minfi" ,r-minfi))) | |
6197 | (home-page | |
6198 | "https://bioconductor.org/packages/IlluminaHumanMethylation450kanno.ilmn12.hg19/") | |
6199 | (synopsis "Annotation for Illumina's 450k methylation arrays") | |
6200 | (description | |
6201 | "This package provides manifests and annotation for Illumina's 450k array | |
6202 | data.") | |
6203 | (license license:artistic2.0))) | |
38babeaa RW |
6204 | |
6205 | (define-public r-watermelon | |
6206 | (package | |
6207 | (name "r-watermelon") | |
9eade229 | 6208 | (version "1.30.0") |
38babeaa RW |
6209 | (source |
6210 | (origin | |
6211 | (method url-fetch) | |
6212 | (uri (bioconductor-uri "wateRmelon" version)) | |
6213 | (sha256 | |
6214 | (base32 | |
9eade229 | 6215 | "0a66fq04yph9dis91lzjk9kh134zy6fj98yklrwf24r1080qngx0")))) |
38babeaa RW |
6216 | (properties `((upstream-name . "wateRmelon"))) |
6217 | (build-system r-build-system) | |
6218 | (propagated-inputs | |
6219 | `(("r-biobase" ,r-biobase) | |
6220 | ("r-illuminahumanmethylation450kanno-ilmn12-hg19" | |
6221 | ,r-illuminahumanmethylation450kanno-ilmn12-hg19) | |
6222 | ("r-illuminaio" ,r-illuminaio) | |
6223 | ("r-limma" ,r-limma) | |
6224 | ("r-lumi" ,r-lumi) | |
6225 | ("r-matrixstats" ,r-matrixstats) | |
6226 | ("r-methylumi" ,r-methylumi) | |
6227 | ("r-roc" ,r-roc))) | |
6228 | (home-page "https://bioconductor.org/packages/wateRmelon/") | |
6229 | (synopsis "Illumina 450 methylation array normalization and metrics") | |
6230 | (description | |
6231 | "The standard index of DNA methylation (beta) is computed from methylated | |
6232 | and unmethylated signal intensities. Betas calculated from raw signal | |
6233 | intensities perform well, but using 11 methylomic datasets we demonstrate that | |
6234 | quantile normalization methods produce marked improvement. The commonly used | |
6235 | procedure of normalizing betas is inferior to the separate normalization of M | |
6236 | and U, and it is also advantageous to normalize Type I and Type II assays | |
6237 | separately. This package provides 15 flavours of betas and three performance | |
6238 | metrics, with methods for objects produced by the @code{methylumi} and | |
6239 | @code{minfi} packages.") | |
6240 | (license license:gpl3))) | |
7d2cb646 RW |
6241 | |
6242 | (define-public r-gdsfmt | |
6243 | (package | |
6244 | (name "r-gdsfmt") | |
f5ef7dd6 | 6245 | (version "1.22.0") |
7d2cb646 RW |
6246 | (source |
6247 | (origin | |
6248 | (method url-fetch) | |
6249 | (uri (bioconductor-uri "gdsfmt" version)) | |
6250 | (sha256 | |
6251 | (base32 | |
f5ef7dd6 | 6252 | "0zc9v62imd0ykz4h30pxa64q0y45qijmkwdk2pd4ncsg8fc2jlz9")) |
7d2cb646 RW |
6253 | (modules '((guix build utils))) |
6254 | ;; Remove bundled sources of zlib, lz4, and xz. Don't attempt to build | |
6255 | ;; them and link with system libraries instead. | |
6256 | (snippet | |
6257 | '(begin | |
6258 | (for-each delete-file-recursively | |
6259 | '("src/LZ4" | |
6260 | "src/XZ" | |
6261 | "src/ZLIB")) | |
6262 | (substitute* "src/Makevars" | |
6263 | (("all: \\$\\(SHLIB\\)") "all:") | |
6264 | (("\\$\\(SHLIB\\): liblzma.a") "") | |
6265 | (("(ZLIB|LZ4)/.*") "") | |
6266 | (("CoreArray/dVLIntGDS.cpp.*") | |
6267 | "CoreArray/dVLIntGDS.cpp") | |
6268 | (("CoreArray/dVLIntGDS.o.*") | |
6269 | "CoreArray/dVLIntGDS.o") | |
6270 | (("PKG_LIBS = ./liblzma.a") | |
6271 | "PKG_LIBS = -llz4")) | |
6272 | (substitute* "src/CoreArray/dStream.h" | |
6273 | (("include \"../(ZLIB|LZ4|XZ/api)/(.*)\"" _ _ header) | |
6274 | (string-append "include <" header ">"))) | |
6275 | #t)))) | |
6276 | (properties `((upstream-name . "gdsfmt"))) | |
6277 | (build-system r-build-system) | |
6278 | (inputs | |
6279 | `(("lz4" ,lz4) | |
6280 | ("xz" ,xz) | |
6281 | ("zlib" ,zlib))) | |
6282 | (home-page "http://corearray.sourceforge.net/") | |
6283 | (synopsis | |
6284 | "R Interface to CoreArray Genomic Data Structure (GDS) Files") | |
6285 | (description | |
6286 | "This package provides a high-level R interface to CoreArray @dfn{Genomic | |
6287 | Data Structure} (GDS) data files, which are portable across platforms with | |
6288 | hierarchical structure to store multiple scalable array-oriented data sets | |
6289 | with metadata information. It is suited for large-scale datasets, especially | |
6290 | for data which are much larger than the available random-access memory. The | |
6291 | @code{gdsfmt} package offers efficient operations specifically designed for | |
6292 | integers of less than 8 bits, since a diploid genotype, like | |
6293 | @dfn{single-nucleotide polymorphism} (SNP), usually occupies fewer bits than a | |
6294 | byte. Data compression and decompression are available with relatively | |
6295 | efficient random access. It is also allowed to read a GDS file in parallel | |
6296 | with multiple R processes supported by the package @code{parallel}.") | |
6297 | (license license:lgpl3))) | |
6b5f59c7 RW |
6298 | |
6299 | (define-public r-bigmelon | |
6300 | (package | |
6301 | (name "r-bigmelon") | |
8b941a50 | 6302 | (version "1.12.0") |
6b5f59c7 RW |
6303 | (source |
6304 | (origin | |
6305 | (method url-fetch) | |
6306 | (uri (bioconductor-uri "bigmelon" version)) | |
6307 | (sha256 | |
6308 | (base32 | |
8b941a50 | 6309 | "0sw7rp4p03m1s72b4j06jfb7as3v1n2w2z4ppk8s4f80fb05bcls")))) |
6b5f59c7 RW |
6310 | (properties `((upstream-name . "bigmelon"))) |
6311 | (build-system r-build-system) | |
6312 | (propagated-inputs | |
6313 | `(("r-biobase" ,r-biobase) | |
6314 | ("r-biocgenerics" ,r-biocgenerics) | |
6315 | ("r-gdsfmt" ,r-gdsfmt) | |
6316 | ("r-geoquery" ,r-geoquery) | |
6317 | ("r-methylumi" ,r-methylumi) | |
6318 | ("r-minfi" ,r-minfi) | |
6319 | ("r-watermelon" ,r-watermelon))) | |
6320 | (home-page "https://bioconductor.org/packages/bigmelon/") | |
6321 | (synopsis "Illumina methylation array analysis for large experiments") | |
6322 | (description | |
6323 | "This package provides methods for working with Illumina arrays using the | |
6324 | @code{gdsfmt} package.") | |
6325 | (license license:gpl3))) | |
739b2d10 | 6326 | |
e5dfcd8e RW |
6327 | (define-public r-seqbias |
6328 | (package | |
6329 | (name "r-seqbias") | |
2223bbc7 | 6330 | (version "1.34.0") |
e5dfcd8e RW |
6331 | (source |
6332 | (origin | |
6333 | (method url-fetch) | |
6334 | (uri (bioconductor-uri "seqbias" version)) | |
6335 | (sha256 | |
6336 | (base32 | |
2223bbc7 | 6337 | "19vbdyjblij2533ibmrw1n0rkqfrbflma6cg5b79ghks0mg7z8hq")))) |
e5dfcd8e RW |
6338 | (properties `((upstream-name . "seqbias"))) |
6339 | (build-system r-build-system) | |
6340 | (propagated-inputs | |
6341 | `(("r-biostrings" ,r-biostrings) | |
6342 | ("r-genomicranges" ,r-genomicranges) | |
6343 | ("r-rhtslib" ,r-rhtslib))) | |
6344 | (inputs | |
6345 | `(("zlib" ,zlib))) ; This comes from rhtslib. | |
6346 | (home-page "https://bioconductor.org/packages/seqbias/") | |
6347 | (synopsis "Estimation of per-position bias in high-throughput sequencing data") | |
6348 | (description | |
6349 | "This package implements a model of per-position sequencing bias in | |
6350 | high-throughput sequencing data using a simple Bayesian network, the structure | |
6351 | and parameters of which are trained on a set of aligned reads and a reference | |
6352 | genome sequence.") | |
6353 | (license license:lgpl3))) | |
6354 | ||
bb0024dc RW |
6355 | (define-public r-reqon |
6356 | (package | |
6357 | (name "r-reqon") | |
02c18abe | 6358 | (version "1.32.0") |
bb0024dc RW |
6359 | (source |
6360 | (origin | |
6361 | (method url-fetch) | |
6362 | (uri (bioconductor-uri "ReQON" version)) | |
6363 | (sha256 | |
6364 | (base32 | |
02c18abe | 6365 | "10p6l2zxijqyypdm970jyfqyrnfhaq3nf7cg2q6mgd1srggfa0cx")))) |
bb0024dc RW |
6366 | (properties `((upstream-name . "ReQON"))) |
6367 | (build-system r-build-system) | |
6368 | (propagated-inputs | |
6369 | `(("r-rjava" ,r-rjava) | |
6370 | ("r-rsamtools" ,r-rsamtools) | |
6371 | ("r-seqbias" ,r-seqbias))) | |
6372 | (home-page "https://bioconductor.org/packages/ReQON/") | |
6373 | (synopsis "Recalibrating quality of nucleotides") | |
6374 | (description | |
6375 | "This package provides an implementation of an algorithm for | |
6376 | recalibrating the base quality scores for aligned sequencing data in BAM | |
6377 | format.") | |
6378 | (license license:gpl2))) | |
6379 | ||
739b2d10 RW |
6380 | (define-public r-wavcluster |
6381 | (package | |
6382 | (name "r-wavcluster") | |
c0cba4b5 | 6383 | (version "2.20.0") |
739b2d10 RW |
6384 | (source |
6385 | (origin | |
6386 | (method url-fetch) | |
6387 | (uri (bioconductor-uri "wavClusteR" version)) | |
6388 | (sha256 | |
6389 | (base32 | |
c0cba4b5 | 6390 | "0vq3xxsvwq86rlya7xc92sc4i6b48sib0pcina3xivg3ky2j3z7y")))) |
739b2d10 RW |
6391 | (properties `((upstream-name . "wavClusteR"))) |
6392 | (build-system r-build-system) | |
6393 | (propagated-inputs | |
6394 | `(("r-biocgenerics" ,r-biocgenerics) | |
6395 | ("r-biostrings" ,r-biostrings) | |
6396 | ("r-foreach" ,r-foreach) | |
6397 | ("r-genomicfeatures" ,r-genomicfeatures) | |
6398 | ("r-genomicranges" ,r-genomicranges) | |
6399 | ("r-ggplot2" ,r-ggplot2) | |
6400 | ("r-hmisc" ,r-hmisc) | |
6401 | ("r-iranges" ,r-iranges) | |
6402 | ("r-mclust" ,r-mclust) | |
6403 | ("r-rsamtools" ,r-rsamtools) | |
6404 | ("r-rtracklayer" ,r-rtracklayer) | |
6405 | ("r-s4vectors" ,r-s4vectors) | |
6406 | ("r-seqinr" ,r-seqinr) | |
6407 | ("r-stringr" ,r-stringr) | |
6408 | ("r-wmtsa" ,r-wmtsa))) | |
6409 | (home-page "https://bioconductor.org/packages/wavClusteR/") | |
6410 | (synopsis "Identification of RNA-protein interaction sites in PAR-CLIP data") | |
6411 | (description | |
6412 | "This package provides an integrated pipeline for the analysis of | |
6413 | PAR-CLIP data. PAR-CLIP-induced transitions are first discriminated from | |
6414 | sequencing errors, SNPs and additional non-experimental sources by a non- | |
6415 | parametric mixture model. The protein binding sites (clusters) are then | |
6416 | resolved at high resolution and cluster statistics are estimated using a | |
6417 | rigorous Bayesian framework. Post-processing of the results, data export for | |
6418 | UCSC genome browser visualization and motif search analysis are provided. In | |
6419 | addition, the package allows to integrate RNA-Seq data to estimate the False | |
6420 | Discovery Rate of cluster detection. Key functions support parallel multicore | |
6421 | computing. While wavClusteR was designed for PAR-CLIP data analysis, it can | |
6422 | be applied to the analysis of other NGS data obtained from experimental | |
6423 | procedures that induce nucleotide substitutions (e.g. BisSeq).") | |
6424 | (license license:gpl2))) | |
853211a5 RW |
6425 | |
6426 | (define-public r-timeseriesexperiment | |
6427 | (package | |
6428 | (name "r-timeseriesexperiment") | |
cb734c60 | 6429 | (version "1.4.0") |
853211a5 RW |
6430 | (source |
6431 | (origin | |
6432 | (method url-fetch) | |
6433 | (uri (bioconductor-uri "TimeSeriesExperiment" version)) | |
6434 | (sha256 | |
6435 | (base32 | |
cb734c60 | 6436 | "0xqa6hzknnci20zx2f6mw5cpqx8pq0v6fzf053hh51p1l2ikvgqm")))) |
853211a5 RW |
6437 | (properties |
6438 | `((upstream-name . "TimeSeriesExperiment"))) | |
6439 | (build-system r-build-system) | |
6440 | (propagated-inputs | |
6441 | `(("r-deseq2" ,r-deseq2) | |
6442 | ("r-dplyr" ,r-dplyr) | |
6443 | ("r-dynamictreecut" ,r-dynamictreecut) | |
6444 | ("r-edger" ,r-edger) | |
6445 | ("r-ggplot2" ,r-ggplot2) | |
6446 | ("r-hmisc" ,r-hmisc) | |
6447 | ("r-limma" ,r-limma) | |
6448 | ("r-magrittr" ,r-magrittr) | |
6449 | ("r-proxy" ,r-proxy) | |
6450 | ("r-s4vectors" ,r-s4vectors) | |
6451 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
6452 | ("r-tibble" ,r-tibble) | |
6453 | ("r-tidyr" ,r-tidyr) | |
6454 | ("r-vegan" ,r-vegan) | |
6455 | ("r-viridis" ,r-viridis))) | |
6456 | (home-page "https://github.com/nlhuong/TimeSeriesExperiment/") | |
6457 | (synopsis "Analysis for short time-series data") | |
6458 | (description | |
6459 | "This package is a visualization and analysis toolbox for short time | |
6460 | course data which includes dimensionality reduction, clustering, two-sample | |
6461 | differential expression testing and gene ranking techniques. The package also | |
6462 | provides methods for retrieving enriched pathways.") | |
6463 | (license license:lgpl3+))) | |
df8576e5 RW |
6464 | |
6465 | (define-public r-variantfiltering | |
6466 | (package | |
6467 | (name "r-variantfiltering") | |
6f5415d5 | 6468 | (version "1.22.0") |
df8576e5 RW |
6469 | (source |
6470 | (origin | |
6471 | (method url-fetch) | |
6472 | (uri (bioconductor-uri "VariantFiltering" version)) | |
6473 | (sha256 | |
6474 | (base32 | |
6f5415d5 | 6475 | "13pgfk2mbffd9smmxnwz7g0jrwng78711053wfzadr107zbyn4r8")))) |
df8576e5 RW |
6476 | (properties |
6477 | `((upstream-name . "VariantFiltering"))) | |
6478 | (build-system r-build-system) | |
6479 | (propagated-inputs | |
6480 | `(("r-annotationdbi" ,r-annotationdbi) | |
6481 | ("r-biobase" ,r-biobase) | |
6482 | ("r-biocgenerics" ,r-biocgenerics) | |
6483 | ("r-biocparallel" ,r-biocparallel) | |
6484 | ("r-biostrings" ,r-biostrings) | |
6485 | ("r-bsgenome" ,r-bsgenome) | |
6486 | ("r-dt" ,r-dt) | |
6487 | ("r-genomeinfodb" ,r-genomeinfodb) | |
6488 | ("r-genomicfeatures" ,r-genomicfeatures) | |
6489 | ("r-genomicranges" ,r-genomicranges) | |
6490 | ("r-genomicscores" ,r-genomicscores) | |
6491 | ("r-graph" ,r-graph) | |
6492 | ("r-gviz" ,r-gviz) | |
6493 | ("r-iranges" ,r-iranges) | |
6494 | ("r-rbgl" ,r-rbgl) | |
6495 | ("r-rsamtools" ,r-rsamtools) | |
6496 | ("r-s4vectors" ,r-s4vectors) | |
6497 | ("r-shiny" ,r-shiny) | |
6498 | ("r-shinyjs" ,r-shinyjs) | |
6499 | ("r-shinythemes" ,r-shinythemes) | |
6500 | ("r-shinytree" ,r-shinytree) | |
6501 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
6502 | ("r-variantannotation" ,r-variantannotation) | |
6503 | ("r-xvector" ,r-xvector))) | |
6504 | (home-page "https://github.com/rcastelo/VariantFiltering") | |
6505 | (synopsis "Filtering of coding and non-coding genetic variants") | |
6506 | (description | |
6507 | "Filter genetic variants using different criteria such as inheritance | |
6508 | model, amino acid change consequence, minor allele frequencies across human | |
6509 | populations, splice site strength, conservation, etc.") | |
6510 | (license license:artistic2.0))) | |
f5349b4d RW |
6511 | |
6512 | (define-public r-genomegraphs | |
6513 | (package | |
6514 | (name "r-genomegraphs") | |
053a2127 | 6515 | (version "1.46.0") |
f5349b4d RW |
6516 | (source |
6517 | (origin | |
6518 | (method url-fetch) | |
6519 | (uri (bioconductor-uri "GenomeGraphs" version)) | |
6520 | (sha256 | |
6521 | (base32 | |
053a2127 | 6522 | "05vavhz936v7cknig2f2mn3fd9fiy54r3swlvifpawramblp1ags")))) |
f5349b4d RW |
6523 | (properties `((upstream-name . "GenomeGraphs"))) |
6524 | (build-system r-build-system) | |
6525 | (propagated-inputs | |
6526 | `(("r-biomart" ,r-biomart))) | |
6527 | (home-page "https://bioconductor.org/packages/GenomeGraphs/") | |
6528 | (synopsis "Plotting genomic information from Ensembl") | |
6529 | (description | |
6530 | "Genomic data analyses requires integrated visualization of known genomic | |
6531 | information and new experimental data. GenomeGraphs uses the biomaRt package | |
6532 | to perform live annotation queries to Ensembl and translates this to e.g. | |
6533 | gene/transcript structures in viewports of the grid graphics package. This | |
6534 | results in genomic information plotted together with your data. Another | |
6535 | strength of GenomeGraphs is to plot different data types such as array CGH, | |
6536 | gene expression, sequencing and other data, together in one plot using the | |
6537 | same genome coordinate system.") | |
6538 | (license license:artistic2.0))) | |
2a360cf6 RW |
6539 | |
6540 | (define-public r-wavetiling | |
6541 | (package | |
6542 | (name "r-wavetiling") | |
e13f9773 | 6543 | (version "1.28.0") |
2a360cf6 RW |
6544 | (source |
6545 | (origin | |
6546 | (method url-fetch) | |
6547 | (uri (bioconductor-uri "waveTiling" version)) | |
6548 | (sha256 | |
6549 | (base32 | |
e13f9773 | 6550 | "0d7l559zlmly8mncmh1zhkqmsml0bwwfpm7ccp8l26y852vwf7hf")))) |
2a360cf6 RW |
6551 | (properties `((upstream-name . "waveTiling"))) |
6552 | (build-system r-build-system) | |
6553 | (propagated-inputs | |
6554 | `(("r-affy" ,r-affy) | |
6555 | ("r-biobase" ,r-biobase) | |
6556 | ("r-biostrings" ,r-biostrings) | |
6557 | ("r-genomegraphs" ,r-genomegraphs) | |
6558 | ("r-genomicranges" ,r-genomicranges) | |
6559 | ("r-iranges" ,r-iranges) | |
6560 | ("r-oligo" ,r-oligo) | |
6561 | ("r-oligoclasses" ,r-oligoclasses) | |
6562 | ("r-preprocesscore" ,r-preprocesscore) | |
6563 | ("r-waveslim" ,r-waveslim))) | |
6564 | (home-page "https://r-forge.r-project.org/projects/wavetiling/") | |
6565 | (synopsis "Wavelet-based models for tiling array transcriptome analysis") | |
6566 | (description | |
6567 | "This package is designed to conduct transcriptome analysis for tiling | |
6568 | arrays based on fast wavelet-based functional models.") | |
6569 | (license license:gpl2+))) | |
d80a1569 RW |
6570 | |
6571 | (define-public r-variancepartition | |
6572 | (package | |
6573 | (name "r-variancepartition") | |
d1ac6430 | 6574 | (version "1.16.1") |
d80a1569 RW |
6575 | (source |
6576 | (origin | |
6577 | (method url-fetch) | |
6578 | (uri (bioconductor-uri "variancePartition" version)) | |
6579 | (sha256 | |
6580 | (base32 | |
d1ac6430 | 6581 | "02pzsff14j4am2d949mh8xgi0c7k44g09q4lr6nqm08vf92brb6g")))) |
d80a1569 RW |
6582 | (properties |
6583 | `((upstream-name . "variancePartition"))) | |
6584 | (build-system r-build-system) | |
6585 | (propagated-inputs | |
6586 | `(("r-biobase" ,r-biobase) | |
326746e1 | 6587 | ("r-biocparallel" ,r-biocparallel) |
d80a1569 RW |
6588 | ("r-colorramps" ,r-colorramps) |
6589 | ("r-doparallel" ,r-doparallel) | |
6590 | ("r-foreach" ,r-foreach) | |
6591 | ("r-ggplot2" ,r-ggplot2) | |
6592 | ("r-gplots" ,r-gplots) | |
6593 | ("r-iterators" ,r-iterators) | |
6594 | ("r-limma" ,r-limma) | |
6595 | ("r-lme4" ,r-lme4) | |
6596 | ("r-lmertest" ,r-lmertest) | |
6597 | ("r-mass" ,r-mass) | |
6598 | ("r-pbkrtest" ,r-pbkrtest) | |
6599 | ("r-progress" ,r-progress) | |
6600 | ("r-reshape2" ,r-reshape2) | |
6601 | ("r-scales" ,r-scales))) | |
6602 | (home-page "https://bioconductor.org/packages/variancePartition/") | |
6603 | (synopsis "Analyze variation in gene expression experiments") | |
6604 | (description | |
6605 | "This is a package providing tools to quantify and interpret multiple | |
6606 | sources of biological and technical variation in gene expression experiments. | |
6607 | It uses a linear mixed model to quantify variation in gene expression | |
6608 | attributable to individual, tissue, time point, or technical variables. The | |
6609 | package includes dream differential expression analysis for repeated | |
6610 | measures.") | |
6611 | (license license:gpl2+))) | |
16e2e4f2 | 6612 | |
6613 | (define-public r-htqpcr | |
6614 | (package | |
6615 | (name "r-htqpcr") | |
0b0906c8 | 6616 | (version "1.40.0") |
16e2e4f2 | 6617 | (source |
6618 | (origin | |
6619 | (method url-fetch) | |
6620 | (uri (bioconductor-uri "HTqPCR" version)) | |
6621 | (sha256 | |
6622 | (base32 | |
0b0906c8 | 6623 | "008iczqaa0wn5nw144vfg3qylg7qa1q963nq9mqhgj3sxlg4rmjx")))) |
16e2e4f2 | 6624 | (properties `((upstream-name . "HTqPCR"))) |
6625 | (build-system r-build-system) | |
6626 | (propagated-inputs | |
6627 | `(("r-affy" ,r-affy) | |
6628 | ("r-biobase" ,r-biobase) | |
6629 | ("r-gplots" ,r-gplots) | |
6630 | ("r-limma" ,r-limma) | |
6631 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
486a0800 TGR |
6632 | (home-page (string-append "https://www.ebi.ac.uk/sites/ebi.ac.uk/files/" |
6633 | "groups/bertone/software/HTqPCR.pdf")) | |
16e2e4f2 | 6634 | (synopsis "Automated analysis of high-throughput qPCR data") |
6635 | (description | |
6636 | "Analysis of Ct values from high throughput quantitative real-time | |
6637 | PCR (qPCR) assays across multiple conditions or replicates. The input data | |
6638 | can be from spatially-defined formats such ABI TaqMan Low Density Arrays or | |
6639 | OpenArray; LightCycler from Roche Applied Science; the CFX plates from Bio-Rad | |
6640 | Laboratories; conventional 96- or 384-well plates; or microfluidic devices | |
6641 | such as the Dynamic Arrays from Fluidigm Corporation. HTqPCR handles data | |
6642 | loading, quality assessment, normalization, visualization and parametric or | |
6643 | non-parametric testing for statistical significance in Ct values between | |
6644 | features (e.g. genes, microRNAs).") | |
6645 | (license license:artistic2.0))) | |
86fb2c63 | 6646 | |
6647 | (define-public r-unifiedwmwqpcr | |
6648 | (package | |
6649 | (name "r-unifiedwmwqpcr") | |
989be6df | 6650 | (version "1.22.0") |
86fb2c63 | 6651 | (source |
6652 | (origin | |
6653 | (method url-fetch) | |
6654 | (uri (bioconductor-uri "unifiedWMWqPCR" version)) | |
6655 | (sha256 | |
6656 | (base32 | |
989be6df | 6657 | "1l6rf7scxxyz4x0m4li54y6905sqj4jrx481zb9h3vqhcfcmn8lj")))) |
86fb2c63 | 6658 | (properties |
6659 | `((upstream-name . "unifiedWMWqPCR"))) | |
6660 | (build-system r-build-system) | |
6661 | (propagated-inputs | |
6662 | `(("r-biocgenerics" ,r-biocgenerics) | |
6663 | ("r-htqpcr" ,r-htqpcr))) | |
6664 | (home-page "https://bioconductor.org/packages/unifiedWMWqPCR") | |
6665 | (synopsis "Unified Wilcoxon-Mann Whitney Test for differential expression in qPCR data") | |
6666 | (description | |
b5b0ee3b | 6667 | "This package implements the unified Wilcoxon-Mann-Whitney Test for qPCR |
86fb2c63 | 6668 | data. This modified test allows for testing differential expression in qPCR |
6669 | data.") | |
6670 | (license license:gpl2+))) | |
72b67e0b RW |
6671 | |
6672 | ;; This is a CRAN package, but it depends on Bioconductor packages, so we put | |
6673 | ;; it here. | |
6674 | (define-public r-activedriverwgs | |
6675 | (package | |
6676 | (name "r-activedriverwgs") | |
6677 | (version "1.0.1") | |
6678 | (source | |
6679 | (origin | |
6680 | (method url-fetch) | |
6681 | (uri (cran-uri "ActiveDriverWGS" version)) | |
6682 | (sha256 | |
6683 | (base32 | |
6684 | "08l9dj8d3cd74z1dqn8n4yqykwvqjxsfa067wnxyh7xnfvvnm5v1")))) | |
6685 | (properties | |
6686 | `((upstream-name . "ActiveDriverWGS"))) | |
6687 | (build-system r-build-system) | |
6688 | (propagated-inputs | |
6689 | `(("r-biostrings" ,r-biostrings) | |
6690 | ("r-bsgenome" ,r-bsgenome) | |
6691 | ("r-bsgenome-hsapiens-ucsc-hg19" ,r-bsgenome-hsapiens-ucsc-hg19) | |
6692 | ("r-genomeinfodb" ,r-genomeinfodb) | |
6693 | ("r-genomicranges" ,r-genomicranges) | |
6694 | ("r-iranges" ,r-iranges) | |
6695 | ("r-plyr" ,r-plyr) | |
6696 | ("r-s4vectors" ,r-s4vectors))) | |
6697 | (home-page "https://cran.r-project.org/web/packages/ActiveDriverWGS/") | |
6698 | (synopsis "Driver discovery tool for cancer whole genomes") | |
6699 | (description | |
6700 | "This package provides a method for finding an enrichment of cancer | |
6701 | simple somatic mutations (SNVs and Indels) in functional elements across the | |
6702 | human genome. ActiveDriverWGS detects coding and noncoding driver elements | |
6703 | using whole genome sequencing data.") | |
6704 | (license license:gpl3))) | |
8e6f63dd RW |
6705 | |
6706 | ;; This is a CRAN package, but it depends on Bioconductor packages, so we put | |
6707 | ;; it here. | |
6708 | (define-public r-activepathways | |
6709 | (package | |
6710 | (name "r-activepathways") | |
6711 | (version "1.0.1") | |
6712 | (source | |
6713 | (origin | |
6714 | (method url-fetch) | |
6715 | (uri (cran-uri "ActivePathways" version)) | |
6716 | (sha256 | |
6717 | (base32 | |
6718 | "1xb0d1svmzw404pv8ja6wr4773k7x2lxkrzrayilvzqbfzj1wx20")))) | |
6719 | (properties | |
6720 | `((upstream-name . "ActivePathways"))) | |
6721 | (build-system r-build-system) | |
6722 | (propagated-inputs | |
6723 | `(("r-data-table" ,r-data-table) | |
6724 | ("r-ggplot2" ,r-ggplot2) | |
6725 | ("r-metap" ,r-metap))) | |
6726 | (home-page "https://cran.r-project.org/web/packages/ActivePathways/") | |
6727 | (synopsis "Multivariate pathway enrichment analysis") | |
6728 | (description | |
6729 | "This package represents an integrative method of analyzing multi omics | |
6730 | data that conducts enrichment analysis of annotated gene sets. ActivePathways | |
6731 | uses a statistical data fusion approach, rationalizes contributing evidence | |
6732 | and highlights associated genes, improving systems-level understanding of | |
6733 | cellular organization in health and disease.") | |
6734 | (license license:gpl3))) | |
d11d6fea RW |
6735 | |
6736 | (define-public r-bgmix | |
6737 | (package | |
6738 | (name "r-bgmix") | |
6739 | (version "1.46.0") | |
6740 | (source | |
6741 | (origin | |
6742 | (method url-fetch) | |
6743 | (uri (bioconductor-uri "BGmix" version)) | |
6744 | (sha256 | |
6745 | (base32 | |
6746 | "1bwqqhkh4m3hhpd71grwjrg7n07lzvys4y7aghmw2gw5ibnk5683")))) | |
6747 | (properties `((upstream-name . "BGmix"))) | |
6748 | (build-system r-build-system) | |
6749 | (propagated-inputs | |
6750 | `(("r-kernsmooth" ,r-kernsmooth))) | |
6751 | (home-page "https://bioconductor.org/packages/BGmix/") | |
6752 | (synopsis "Bayesian models for differential gene expression") | |
6753 | (description | |
6754 | "This package provides fully Bayesian mixture models for differential | |
6755 | gene expression.") | |
6756 | (license license:gpl2))) | |
75eb1149 RW |
6757 | |
6758 | (define-public r-bgx | |
6759 | (package | |
6760 | (name "r-bgx") | |
6761 | (version "1.52.0") | |
6762 | (source | |
6763 | (origin | |
6764 | (method url-fetch) | |
6765 | (uri (bioconductor-uri "bgx" version)) | |
6766 | (sha256 | |
6767 | (base32 | |
6768 | "0fiqqv6pin0zhxaw67hzfjccq2qkl9qfqjf10nx2zmpxm2licavm")))) | |
6769 | (properties `((upstream-name . "bgx"))) | |
6770 | (build-system r-build-system) | |
6771 | (propagated-inputs | |
6772 | `(("r-affy" ,r-affy) | |
6773 | ("r-biobase" ,r-biobase) | |
6774 | ("r-gcrma" ,r-gcrma) | |
6775 | ("r-rcpp" ,r-rcpp))) | |
6776 | (home-page "https://bioconductor.org/packages/bgx/") | |
6777 | (synopsis "Bayesian gene expression") | |
6778 | (description | |
6779 | "This package provides tools for Bayesian integrated analysis of | |
6780 | Affymetrix GeneChips.") | |
6781 | (license license:gpl2))) | |
6bd50acf RW |
6782 | |
6783 | (define-public r-bhc | |
6784 | (package | |
6785 | (name "r-bhc") | |
6786 | (version "1.38.0") | |
6787 | (source | |
6788 | (origin | |
6789 | (method url-fetch) | |
6790 | (uri (bioconductor-uri "BHC" version)) | |
6791 | (sha256 | |
6792 | (base32 | |
6793 | "1bxx3jak8mgvay3j1xd59bb9j86pzl6hh5abxww9x1b7rswmy1jh")))) | |
6794 | (properties `((upstream-name . "BHC"))) | |
6795 | (build-system r-build-system) | |
6796 | (home-page "https://bioconductor.org/packages/BHC/") | |
6797 | (synopsis "Bayesian hierarchical clustering") | |
6798 | (description | |
6799 | "The method implemented in this package performs bottom-up hierarchical | |
6800 | clustering, using a Dirichlet Process (infinite mixture) to model uncertainty | |
6801 | in the data and Bayesian model selection to decide at each step which clusters | |
6802 | to merge. This avoids several limitations of traditional methods, for example | |
6803 | how many clusters there should be and how to choose a principled distance | |
6804 | metric. This implementation accepts multinomial (i.e. discrete, with 2+ | |
6805 | categories) or time-series data. This version also includes a randomised | |
6806 | algorithm which is more efficient for larger data sets.") | |
6807 | (license license:gpl3))) | |
de9374b7 RW |
6808 | |
6809 | (define-public r-bicare | |
6810 | (package | |
6811 | (name "r-bicare") | |
6812 | (version "1.44.0") | |
6813 | (source | |
6814 | (origin | |
6815 | (method url-fetch) | |
6816 | (uri (bioconductor-uri "BicARE" version)) | |
6817 | (sha256 | |
6818 | (base32 | |
6819 | "1gia5vzmvbk4k1vx3bh9nld1ws9s3c0y11qfbzqhfnfjbd7n8qcs")))) | |
6820 | (properties `((upstream-name . "BicARE"))) | |
6821 | (build-system r-build-system) | |
6822 | (propagated-inputs | |
6823 | `(("r-biobase" ,r-biobase) | |
6824 | ("r-gseabase" ,r-gseabase) | |
6825 | ("r-multtest" ,r-multtest))) | |
6826 | (home-page "http://bioinfo.curie.fr") | |
6827 | (synopsis "Biclustering analysis and results exploration") | |
6828 | (description | |
6829 | "This is a package for biclustering analysis and exploration of | |
6830 | results.") | |
6831 | (license license:gpl2))) | |
40fe63ad RW |
6832 | |
6833 | (define-public r-bifet | |
6834 | (package | |
6835 | (name "r-bifet") | |
6836 | (version "1.6.0") | |
6837 | (source | |
6838 | (origin | |
6839 | (method url-fetch) | |
6840 | (uri (bioconductor-uri "BiFET" version)) | |
6841 | (sha256 | |
6842 | (base32 | |
6843 | "0ck1d6hxd4f40hfz8p2z5xmjbz79yhrf6fisjka2xzk5v9fm4p4k")))) | |
6844 | (properties `((upstream-name . "BiFET"))) | |
6845 | (build-system r-build-system) | |
6846 | (propagated-inputs | |
6847 | `(("r-genomicranges" ,r-genomicranges) | |
6848 | ("r-poibin" ,r-poibin))) | |
6849 | (home-page "https://bioconductor.org/packages/BiFET") | |
6850 | (synopsis "Bias-free footprint enrichment test") | |
6851 | (description | |
6852 | "BiFET identifies @dfn{transcription factors} (TFs) whose footprints are | |
6853 | over-represented in target regions compared to background regions after | |
6854 | correcting for the bias arising from the imbalance in read counts and GC | |
6855 | contents between the target and background regions. For a given TF k, BiFET | |
6856 | tests the null hypothesis that the target regions have the same probability of | |
6857 | having footprints for the TF k as the background regions while correcting for | |
6858 | the read count and GC content bias.") | |
6859 | (license license:gpl3))) | |
e823337c RW |
6860 | |
6861 | (define-public r-rsbml | |
6862 | (package | |
6863 | (name "r-rsbml") | |
6864 | (version "2.44.0") | |
6865 | (source | |
6866 | (origin | |
6867 | (method url-fetch) | |
6868 | (uri (bioconductor-uri "rsbml" version)) | |
6869 | (sha256 | |
6870 | (base32 | |
6871 | "1dbp0aaijxn3na26b68ws0v9qzvml61ifb9z4i8pz7q6h48n7lxa")))) | |
6872 | (properties `((upstream-name . "rsbml"))) | |
6873 | (build-system r-build-system) | |
6874 | (inputs | |
6875 | `(("libsbml" ,libsbml) | |
6876 | ("zlib" ,zlib))) | |
6877 | (propagated-inputs | |
6878 | `(("r-biocgenerics" ,r-biocgenerics) | |
6879 | ("r-graph" ,r-graph))) | |
6880 | (native-inputs | |
6881 | `(("pkg-config" ,pkg-config))) | |
6882 | (home-page "http://www.sbml.org") | |
6883 | (synopsis "R support for SBML") | |
6884 | (description | |
6885 | "This package provides an R interface to libsbml for SBML parsing, | |
6886 | validating output, provides an S4 SBML DOM, converts SBML to R graph objects.") | |
6887 | (license license:artistic2.0))) | |
75a8bb31 RW |
6888 | |
6889 | (define-public r-hypergraph | |
6890 | (package | |
6891 | (name "r-hypergraph") | |
6892 | (version "1.58.0") | |
6893 | (source | |
6894 | (origin | |
6895 | (method url-fetch) | |
6896 | (uri (bioconductor-uri "hypergraph" version)) | |
6897 | (sha256 | |
6898 | (base32 | |
6899 | "1bixmslxy7r987zw1vf4dg72hfi04lf4vj03n7ygym2g8nfhbh7m")))) | |
6900 | (properties `((upstream-name . "hypergraph"))) | |
6901 | (build-system r-build-system) | |
6902 | (propagated-inputs | |
6903 | `(("r-graph" ,r-graph))) | |
6904 | (home-page "https://bioconductor.org/packages/hypergraph") | |
6905 | (synopsis "Hypergraph data structures") | |
6906 | (description | |
6907 | "This package implements some simple capabilities for representing and | |
6908 | manipulating hypergraphs.") | |
6909 | (license license:artistic2.0))) | |
5aef09bd RW |
6910 | |
6911 | (define-public r-hyperdraw | |
6912 | (package | |
6913 | (name "r-hyperdraw") | |
6914 | (version "1.38.0") | |
6915 | (source | |
6916 | (origin | |
6917 | (method url-fetch) | |
6918 | (uri (bioconductor-uri "hyperdraw" version)) | |
6919 | (sha256 | |
6920 | (base32 | |
6921 | "0a8h3pb7196qi49ady8ni92m5wqb1hvxw6khk9j63mwj3h7jinbj")))) | |
6922 | (properties `((upstream-name . "hyperdraw"))) | |
6923 | (build-system r-build-system) | |
6924 | (inputs `(("graphviz" ,graphviz))) | |
6925 | (propagated-inputs | |
6926 | `(("r-graph" ,r-graph) | |
6927 | ("r-hypergraph" ,r-hypergraph) | |
6928 | ("r-rgraphviz" ,r-rgraphviz))) | |
6929 | (home-page "https://bioconductor.org/packages/hyperdraw") | |
6930 | (synopsis "Visualizing hypergraphs") | |
6931 | (description | |
6932 | "This package provides functions for visualizing hypergraphs.") | |
6933 | (license license:gpl2+))) | |
6ca6f866 RW |
6934 | |
6935 | (define-public r-biggr | |
6936 | (package | |
6937 | (name "r-biggr") | |
6938 | (version "1.22.0") | |
6939 | (source | |
6940 | (origin | |
6941 | (method url-fetch) | |
6942 | (uri (bioconductor-uri "BiGGR" version)) | |
6943 | (sha256 | |
6944 | (base32 | |
6945 | "1n2ypc84abmhn6br0yi87k7lvjc11k7abzhgvzdabc2ai1qgcqif")))) | |
6946 | (properties `((upstream-name . "BiGGR"))) | |
6947 | (build-system r-build-system) | |
6948 | (propagated-inputs | |
6949 | `(("r-hyperdraw" ,r-hyperdraw) | |
6950 | ("r-hypergraph" ,r-hypergraph) | |
6951 | ("r-lim" ,r-lim) | |
6952 | ("r-limsolve" ,r-limsolve) | |
6953 | ("r-rsbml" ,r-rsbml) | |
6954 | ("r-stringr" ,r-stringr))) | |
6955 | (home-page "https://bioconductor.org/packages/BiGGR/") | |
6956 | (synopsis "Constraint based modeling using metabolic reconstruction databases") | |
6957 | (description | |
6958 | "This package provides an interface to simulate metabolic reconstruction | |
6959 | from the @url{http://bigg.ucsd.edu/, BiGG database} and other metabolic | |
6960 | reconstruction databases. The package facilitates @dfn{flux balance | |
6961 | analysis} (FBA) and the sampling of feasible flux distributions. Metabolic | |
6962 | networks and estimated fluxes can be visualized with hypergraphs.") | |
6963 | (license license:gpl3+))) | |
820373db RW |
6964 | |
6965 | (define-public r-bigmemoryextras | |
6966 | (package | |
6967 | (name "r-bigmemoryextras") | |
6968 | (version "1.34.0") | |
6969 | (source | |
6970 | (origin | |
6971 | (method url-fetch) | |
6972 | (uri (bioconductor-uri "bigmemoryExtras" version)) | |
6973 | (sha256 | |
6974 | (base32 | |
6975 | "17dk7c44ikphcrpi8hnxyvlmj30qmj098kc0ihfi69bp9rw1cibq")))) | |
6976 | (properties | |
6977 | `((upstream-name . "bigmemoryExtras"))) | |
6978 | (build-system r-build-system) | |
6979 | (propagated-inputs | |
6980 | `(("r-bigmemory" ,r-bigmemory))) | |
6981 | (home-page "https://github.com/phaverty/bigmemoryExtras") | |
6982 | (synopsis "Extension of the bigmemory package") | |
6983 | (description | |
6984 | "This package defines a @code{BigMatrix} @code{ReferenceClass} which adds | |
6985 | safety and convenience features to the @code{filebacked.big.matrix} class from | |
6986 | the @code{bigmemory} package. @code{BigMatrix} protects against segfaults by | |
6987 | monitoring and gracefully restoring the connection to on-disk data and it also | |
6988 | protects against accidental data modification with a filesystem-based | |
6989 | permissions system. Utilities are provided for using @code{BigMatrix}-derived | |
6990 | classes as @code{assayData} matrices within the @code{Biobase} package's | |
6991 | @code{eSet} family of classes. @code{BigMatrix} provides some optimizations | |
6992 | related to attaching to, and indexing into, file-backed matrices with | |
6993 | dimnames. Additionally, the package provides a @code{BigMatrixFactor} class, | |
6994 | a file-backed matrix with factor properties.") | |
6995 | (license license:artistic2.0))) | |
d38775b1 RW |
6996 | |
6997 | (define-public r-bigpint | |
6998 | (package | |
6999 | (name "r-bigpint") | |
7000 | (version "1.2.0") | |
7001 | (source | |
7002 | (origin | |
7003 | (method url-fetch) | |
7004 | (uri (bioconductor-uri "bigPint" version)) | |
7005 | (sha256 | |
7006 | (base32 | |
7007 | "10vs0lzfyxp6sm4r9pxfwipjvzmmaqnvwn1hc5q37s5qz44fg0hk")))) | |
7008 | (properties `((upstream-name . "bigPint"))) | |
7009 | (build-system r-build-system) | |
7010 | (propagated-inputs | |
7011 | `(("r-dplyr" ,r-dplyr) | |
7012 | ("r-ggally" ,r-ggally) | |
7013 | ("r-ggplot2" ,r-ggplot2) | |
7014 | ("r-gridextra" ,r-gridextra) | |
7015 | ("r-hexbin" ,r-hexbin) | |
7016 | ("r-hmisc" ,r-hmisc) | |
7017 | ("r-htmlwidgets" ,r-htmlwidgets) | |
7018 | ("r-plotly" ,r-plotly) | |
7019 | ("r-plyr" ,r-plyr) | |
7020 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
7021 | ("r-reshape" ,r-reshape) | |
7022 | ("r-shiny" ,r-shiny) | |
7023 | ("r-shinycssloaders" ,r-shinycssloaders) | |
7024 | ("r-shinydashboard" ,r-shinydashboard) | |
7025 | ("r-stringr" ,r-stringr) | |
7026 | ("r-tidyr" ,r-tidyr))) | |
7027 | (home-page "https://github.com/lindsayrutter/bigPint") | |
7028 | (synopsis "Big multivariate data plotted interactively") | |
7029 | (description | |
7030 | "This package provides methods for visualizing large multivariate | |
7031 | datasets using static and interactive scatterplot matrices, parallel | |
7032 | coordinate plots, volcano plots, and litre plots. It includes examples for | |
7033 | visualizing RNA-sequencing datasets and differentially expressed genes.") | |
7034 | (license license:gpl3))) | |
991554fc RW |
7035 | |
7036 | (define-public r-chemminer | |
7037 | (package | |
7038 | (name "r-chemminer") | |
7039 | (version "3.38.0") | |
7040 | (source | |
7041 | (origin | |
7042 | (method url-fetch) | |
7043 | (uri (bioconductor-uri "ChemmineR" version)) | |
7044 | (sha256 | |
7045 | (base32 | |
7046 | "1j6vmkhc03dmmkm5wgbcv62pw5dclp49f906xkx1pwg27bdldbga")))) | |
7047 | (properties `((upstream-name . "ChemmineR"))) | |
7048 | (build-system r-build-system) | |
7049 | (propagated-inputs | |
7050 | `(("r-base64enc" ,r-base64enc) | |
7051 | ("r-bh" ,r-bh) | |
7052 | ("r-biocgenerics" ,r-biocgenerics) | |
7053 | ("r-dbi" ,r-dbi) | |
7054 | ("r-digest" ,r-digest) | |
7055 | ("r-dt" ,r-dt) | |
7056 | ("r-ggplot2" ,r-ggplot2) | |
7057 | ("r-gridextra" ,r-gridextra) | |
7058 | ("r-png" ,r-png) | |
7059 | ("r-rcpp" ,r-rcpp) | |
7060 | ("r-rcurl" ,r-rcurl) | |
7061 | ("r-rjson" ,r-rjson) | |
7062 | ("r-rsvg" ,r-rsvg))) | |
7063 | (home-page "https://github.com/girke-lab/ChemmineR") | |
7064 | (synopsis "Cheminformatics toolkit for R") | |
7065 | (description | |
7066 | "ChemmineR is a cheminformatics package for analyzing drug-like small | |
7067 | molecule data in R. It contains functions for efficient processing of large | |
7068 | numbers of molecules, physicochemical/structural property predictions, | |
7069 | structural similarity searching, classification and clustering of compound | |
7070 | libraries with a wide spectrum of algorithms. In addition, it offers | |
7071 | visualization functions for compound clustering results and chemical | |
7072 | structures.") | |
7073 | (license license:artistic2.0))) | |
48bcbef0 RW |
7074 | |
7075 | (define-public r-bioassayr | |
7076 | (package | |
7077 | (name "r-bioassayr") | |
7078 | (version "1.24.0") | |
7079 | (source | |
7080 | (origin | |
7081 | (method url-fetch) | |
7082 | (uri (bioconductor-uri "bioassayR" version)) | |
7083 | (sha256 | |
7084 | (base32 | |
7085 | "08vxkvxhqnryfbj4dwk3ifb9pn544www9zk2pj9fjbh5xfpwi7zw")))) | |
7086 | (properties `((upstream-name . "bioassayR"))) | |
7087 | (build-system r-build-system) | |
7088 | (propagated-inputs | |
7089 | `(("r-biocgenerics" ,r-biocgenerics) | |
7090 | ("r-chemminer" ,r-chemminer) | |
7091 | ("r-dbi" ,r-dbi) | |
7092 | ("r-matrix" ,r-matrix) | |
7093 | ("r-rjson" ,r-rjson) | |
7094 | ("r-rsqlite" ,r-rsqlite) | |
7095 | ("r-xml" ,r-xml))) | |
7096 | (home-page "https://github.com/TylerBackman/bioassayR") | |
7097 | (synopsis "Cross-target analysis of small molecule bioactivity") | |
7098 | (description | |
7099 | "bioassayR is a computational tool that enables simultaneous analysis of | |
7100 | thousands of bioassay experiments performed over a diverse set of compounds | |
7101 | and biological targets. Unique features include support for large-scale | |
7102 | cross-target analyses of both public and custom bioassays, generation of | |
7103 | @dfn{high throughput screening fingerprints} (HTSFPs), and an optional | |
7104 | preloaded database that provides access to a substantial portion of publicly | |
7105 | available bioactivity data.") | |
7106 | (license license:artistic2.0))) | |
29fd736a RW |
7107 | |
7108 | (define-public r-biobroom | |
7109 | (package | |
7110 | (name "r-biobroom") | |
7111 | (version "1.18.0") | |
7112 | (source | |
7113 | (origin | |
7114 | (method url-fetch) | |
7115 | (uri (bioconductor-uri "biobroom" version)) | |
7116 | (sha256 | |
7117 | (base32 | |
7118 | "1480ycdsh9xdhbpr47vdw5g6m8arqsnp8hc19wwhzm8npxh4qqlb")))) | |
7119 | (properties `((upstream-name . "biobroom"))) | |
7120 | (build-system r-build-system) | |
7121 | (propagated-inputs | |
7122 | `(("r-biobase" ,r-biobase) | |
7123 | ("r-broom" ,r-broom) | |
7124 | ("r-dplyr" ,r-dplyr) | |
7125 | ("r-tidyr" ,r-tidyr))) | |
7126 | (home-page "https://github.com/StoreyLab/biobroom") | |
7127 | (synopsis "Turn Bioconductor objects into tidy data frames") | |
7128 | (description | |
7129 | "This package contains methods for converting standard objects | |
7130 | constructed by bioinformatics packages, especially those in Bioconductor, and | |
7131 | converting them to @code{tidy} data. It thus serves as a complement to the | |
7132 | @code{broom} package, and follows the same tidy, augment, glance division of | |
7133 | tidying methods. Tidying data makes it easy to recombine, reshape and | |
7134 | visualize bioinformatics analyses.") | |
7135 | ;; Any version of the LGPL. | |
7136 | (license license:lgpl3+))) | |
c373223e RW |
7137 | |
7138 | (define-public r-graphite | |
7139 | (package | |
7140 | (name "r-graphite") | |
7141 | (version "1.32.0") | |
7142 | (source | |
7143 | (origin | |
7144 | (method url-fetch) | |
7145 | (uri (bioconductor-uri "graphite" version)) | |
7146 | (sha256 | |
7147 | (base32 | |
7148 | "1r9fk0cpdwm7012pa85dkjcpkml2j89zcznpf4hfdz66anfyyycd")))) | |
7149 | (properties `((upstream-name . "graphite"))) | |
7150 | (build-system r-build-system) | |
7151 | (propagated-inputs | |
7152 | `(("r-annotationdbi" ,r-annotationdbi) | |
7153 | ("r-checkmate" ,r-checkmate) | |
7154 | ("r-graph" ,r-graph) | |
7155 | ("r-httr" ,r-httr) | |
7156 | ("r-rappdirs" ,r-rappdirs))) | |
7157 | (home-page "https://bioconductor.org/packages/graphite/") | |
7158 | (synopsis "Networks from pathway databases") | |
7159 | (description | |
7160 | "Graphite provides networks derived from eight public pathway databases, | |
7161 | and automates the conversion of node identifiers (e.g. from Entrez IDs to gene | |
7162 | symbols).") | |
7163 | (license license:agpl3+))) | |
f388834e RW |
7164 | |
7165 | (define-public r-reactomepa | |
7166 | (package | |
7167 | (name "r-reactomepa") | |
7168 | (version "1.30.0") | |
7169 | (source | |
7170 | (origin | |
7171 | (method url-fetch) | |
7172 | (uri (bioconductor-uri "ReactomePA" version)) | |
7173 | (sha256 | |
7174 | (base32 | |
7175 | "1vwc9kj1l4yi7c4f4lnq0i3wl2nrmmhcxyakz8qak122fi92z3j1")))) | |
7176 | (properties `((upstream-name . "ReactomePA"))) | |
7177 | (build-system r-build-system) | |
7178 | (propagated-inputs | |
7179 | `(("r-annotationdbi" ,r-annotationdbi) | |
7180 | ("r-dose" ,r-dose) | |
7181 | ("r-enrichplot" ,r-enrichplot) | |
7182 | ("r-ggplot2" ,r-ggplot2) | |
7183 | ("r-ggraph" ,r-ggraph) | |
7184 | ("r-graphite" ,r-graphite) | |
7185 | ("r-igraph" ,r-igraph) | |
7186 | ("r-reactome-db" ,r-reactome-db))) | |
7187 | (home-page "https://guangchuangyu.github.io/software/ReactomePA") | |
7188 | (synopsis "Reactome pathway analysis") | |
7189 | (description | |
7190 | "This package provides functions for pathway analysis based on the | |
7191 | REACTOME pathway database. It implements enrichment analysis, gene set | |
7192 | enrichment analysis and several functions for visualization.") | |
7193 | (license license:gpl2))) | |
21afe920 RW |
7194 | |
7195 | (define-public r-ebarrays | |
7196 | (package | |
7197 | (name "r-ebarrays") | |
7198 | (version "2.50.0") | |
7199 | (source | |
7200 | (origin | |
7201 | (method url-fetch) | |
7202 | (uri (bioconductor-uri "EBarrays" version)) | |
7203 | (sha256 | |
7204 | (base32 | |
7205 | "063rhsdp8x0f881kslq06zxfp6b2qabrz4vmfrn8a4v3pd3n7s13")))) | |
7206 | (properties `((upstream-name . "EBarrays"))) | |
7207 | (build-system r-build-system) | |
7208 | (propagated-inputs | |
7209 | `(("r-biobase" ,r-biobase) | |
7210 | ("r-cluster" ,r-cluster) | |
7211 | ("r-lattice" ,r-lattice))) | |
7212 | (home-page "https://bioconductor.org/packages/EBarrays/") | |
7213 | (synopsis "Gene clustering and differential expression identification") | |
7214 | (description | |
7215 | "EBarrays provides tools for the analysis of replicated/unreplicated | |
7216 | microarray data.") | |
7217 | (license license:gpl2+))) | |
f180be29 RW |
7218 | |
7219 | (define-public r-bioccasestudies | |
7220 | (package | |
7221 | (name "r-bioccasestudies") | |
7222 | (version "1.48.0") | |
7223 | (source | |
7224 | (origin | |
7225 | (method url-fetch) | |
7226 | (uri (bioconductor-uri "BiocCaseStudies" version)) | |
7227 | (sha256 | |
7228 | (base32 | |
7229 | "1sg9vxs24zfz3dg9y0qlrdsq43y0pbahbvcfxzlxjzjw80xzxpbd")))) | |
7230 | (properties | |
7231 | `((upstream-name . "BiocCaseStudies"))) | |
7232 | (build-system r-build-system) | |
7233 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
7234 | (home-page "https://bioconductor.org/packages/BiocCaseStudies") | |
7235 | (synopsis "Support for the case studies monograph") | |
7236 | (description | |
7237 | "This package provides software and data to support the case studies | |
7238 | monograph.") | |
7239 | (license license:artistic2.0))) | |
49f0860b RW |
7240 | |
7241 | (define-public r-biocgraph | |
7242 | (package | |
7243 | (name "r-biocgraph") | |
7244 | (version "1.48.0") | |
7245 | (source | |
7246 | (origin | |
7247 | (method url-fetch) | |
7248 | (uri (bioconductor-uri "biocGraph" version)) | |
7249 | (sha256 | |
7250 | (base32 | |
7251 | "1rv2lwiqwg7h7za23n896fs4dpla3xhw6kzwghb6iw5nlm2m61yw")))) | |
7252 | (properties `((upstream-name . "biocGraph"))) | |
7253 | (build-system r-build-system) | |
7254 | (propagated-inputs | |
7255 | `(("r-biocgenerics" ,r-biocgenerics) | |
7256 | ("r-geneplotter" ,r-geneplotter) | |
7257 | ("r-graph" ,r-graph) | |
7258 | ("r-rgraphviz" ,r-rgraphviz))) | |
7259 | (home-page "https://bioconductor.org/packages/biocGraph/") | |
7260 | (synopsis "Graph examples and use cases in Bioinformatics") | |
7261 | (description | |
7262 | "This package provides examples and code that make use of the | |
7263 | different graph related packages produced by Bioconductor.") | |
7264 | (license license:artistic2.0))) | |
244270e6 RW |
7265 | |
7266 | (define-public r-experimenthub | |
7267 | (package | |
7268 | (name "r-experimenthub") | |
7269 | (version "1.12.0") | |
7270 | (source | |
7271 | (origin | |
7272 | (method url-fetch) | |
7273 | (uri (bioconductor-uri "ExperimentHub" version)) | |
7274 | (sha256 | |
7275 | (base32 | |
7276 | "054w2lkyirbmhgia0rp4nk9zzw3zphz6jxg6fc9zlarp90g64z24")))) | |
7277 | (properties `((upstream-name . "ExperimentHub"))) | |
7278 | (build-system r-build-system) | |
7279 | (propagated-inputs | |
7280 | `(("r-annotationhub" ,r-annotationhub) | |
7281 | ("r-biocfilecache" ,r-biocfilecache) | |
7282 | ("r-biocgenerics" ,r-biocgenerics) | |
7283 | ("r-biocmanager" ,r-biocmanager) | |
7284 | ("r-curl" ,r-curl) | |
7285 | ("r-rappdirs" ,r-rappdirs) | |
7286 | ("r-s4vectors" ,r-s4vectors))) | |
7287 | (home-page "https://bioconductor.org/packages/ExperimentHub/") | |
7288 | (synopsis "Client to access ExperimentHub resources") | |
7289 | (description | |
7290 | "This package provides a client for the Bioconductor ExperimentHub web | |
7291 | resource. ExperimentHub provides a central location where curated data from | |
7292 | experiments, publications or training courses can be accessed. Each resource | |
7293 | has associated metadata, tags and date of modification. The client creates | |
7294 | and manages a local cache of files retrieved enabling quick and reproducible | |
7295 | access.") | |
7296 | (license license:artistic2.0))) | |
06784793 RW |
7297 | |
7298 | (define-public r-multiassayexperiment | |
7299 | (package | |
7300 | (name "r-multiassayexperiment") | |
67133278 | 7301 | (version "1.12.4") |
06784793 RW |
7302 | (source |
7303 | (origin | |
7304 | (method url-fetch) | |
7305 | (uri (bioconductor-uri "MultiAssayExperiment" version)) | |
7306 | (sha256 | |
7307 | (base32 | |
67133278 | 7308 | "01cnp00y5bk551c8gqgqp5468dvccg72i0rvh5cxgbx1c42zy6xn")))) |
06784793 RW |
7309 | (properties |
7310 | `((upstream-name . "MultiAssayExperiment"))) | |
7311 | (build-system r-build-system) | |
7312 | (propagated-inputs | |
7313 | `(("r-biobase" ,r-biobase) | |
7314 | ("r-biocgenerics" ,r-biocgenerics) | |
7315 | ("r-genomicranges" ,r-genomicranges) | |
7316 | ("r-iranges" ,r-iranges) | |
7317 | ("r-s4vectors" ,r-s4vectors) | |
7318 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
7319 | ("r-tidyr" ,r-tidyr))) | |
798ca8d0 | 7320 | (home-page "https://waldronlab.io/MultiAssayExperiment/") |
06784793 RW |
7321 | (synopsis "Integration of multi-omics experiments in Bioconductor") |
7322 | (description | |
7323 | "MultiAssayExperiment harmonizes data management of multiple assays | |
7324 | performed on an overlapping set of specimens. It provides a familiar | |
7325 | Bioconductor user experience by extending concepts from | |
7326 | @code{SummarizedExperiment}, supporting an open-ended mix of standard data | |
7327 | classes for individual assays, and allowing subsetting by genomic ranges or | |
7328 | rownames.") | |
7329 | (license license:artistic2.0))) | |
c2b36a04 RW |
7330 | |
7331 | (define-public r-bioconcotk | |
7332 | (package | |
7333 | (name "r-bioconcotk") | |
7334 | (version "1.6.0") | |
7335 | (source | |
7336 | (origin | |
7337 | (method url-fetch) | |
7338 | (uri (bioconductor-uri "BiocOncoTK" version)) | |
7339 | (sha256 | |
7340 | (base32 | |
7341 | "0rnah6c01a33yb9663jim9iclan61rpcwprb56mykgn1pf5hywbj")))) | |
7342 | (properties `((upstream-name . "BiocOncoTK"))) | |
7343 | (build-system r-build-system) | |
7344 | (propagated-inputs | |
7345 | `(("r-bigrquery" ,r-bigrquery) | |
7346 | ("r-car" ,r-car) | |
7347 | ("r-complexheatmap" ,r-complexheatmap) | |
7348 | ("r-curatedtcgadata" ,r-curatedtcgadata) | |
7349 | ("r-dbi" ,r-dbi) | |
7350 | ("r-dplyr" ,r-dplyr) | |
7351 | ("r-dt" ,r-dt) | |
7352 | ("r-genomicfeatures" ,r-genomicfeatures) | |
7353 | ("r-genomicranges" ,r-genomicranges) | |
7354 | ("r-ggplot2" ,r-ggplot2) | |
7355 | ("r-ggpubr" ,r-ggpubr) | |
7356 | ("r-graph" ,r-graph) | |
7357 | ("r-httr" ,r-httr) | |
7358 | ("r-iranges" ,r-iranges) | |
7359 | ("r-magrittr" ,r-magrittr) | |
7360 | ("r-plyr" ,r-plyr) | |
7361 | ("r-rgraphviz" ,r-rgraphviz) | |
7362 | ("r-rjson" ,r-rjson) | |
7363 | ("r-s4vectors" ,r-s4vectors) | |
7364 | ("r-scales" ,r-scales) | |
7365 | ("r-shiny" ,r-shiny) | |
7366 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
7367 | (home-page "https://bioconductor.org/packages/BiocOncoTK") | |
7368 | (synopsis "Bioconductor components for general cancer genomics") | |
7369 | (description | |
7370 | "The purpose of this package is to provide a central interface to various | |
7371 | tools for genome-scale analysis of cancer studies.") | |
7372 | (license license:artistic2.0))) | |
4d12c1e3 RW |
7373 | |
7374 | (define-public r-biocor | |
7375 | (package | |
7376 | (name "r-biocor") | |
7377 | (version "1.10.0") | |
7378 | (source | |
7379 | (origin | |
7380 | (method url-fetch) | |
7381 | (uri (bioconductor-uri "BioCor" version)) | |
7382 | (sha256 | |
7383 | (base32 | |
7384 | "1bjw02rwmz2d715sgpfp08njb15200ch7cmipsf9hd5835ppg1jl")))) | |
7385 | (properties `((upstream-name . "BioCor"))) | |
7386 | (build-system r-build-system) | |
7387 | (propagated-inputs | |
7388 | `(("r-biocparallel" ,r-biocparallel) | |
7389 | ("r-gseabase" ,r-gseabase) | |
7390 | ("r-matrix" ,r-matrix))) | |
7391 | (home-page "https://llrs.github.io/BioCor/") | |
7392 | (synopsis "Functional similarities") | |
7393 | (description | |
7394 | "This package provides tools to calculate functional similarities based | |
7395 | on the pathways described on KEGG and REACTOME or in gene sets. These | |
7396 | similarities can be calculated for pathways or gene sets, genes, or clusters | |
7397 | and combined with other similarities. They can be used to improve networks, | |
7398 | gene selection, testing relationships, and so on.") | |
7399 | (license license:expat))) | |
4a18112d RW |
7400 | |
7401 | (define-public r-biocpkgtools | |
7402 | (package | |
7403 | (name "r-biocpkgtools") | |
2d6a7bca | 7404 | (version "1.4.6") |
4a18112d RW |
7405 | (source |
7406 | (origin | |
7407 | (method url-fetch) | |
7408 | (uri (bioconductor-uri "BiocPkgTools" version)) | |
7409 | (sha256 | |
7410 | (base32 | |
2d6a7bca | 7411 | "0grwnmncmpqcplbfw3j210m1a8f7mmdizklh4zksg4ic21dpjj1a")))) |
4a18112d RW |
7412 | (properties `((upstream-name . "BiocPkgTools"))) |
7413 | (build-system r-build-system) | |
7414 | (propagated-inputs | |
2d6a7bca RW |
7415 | `(("r-biocfilecache" ,r-biocfilecache) |
7416 | ("r-biocmanager" ,r-biocmanager) | |
4a18112d RW |
7417 | ("r-biocviews" ,r-biocviews) |
7418 | ("r-dplyr" ,r-dplyr) | |
7419 | ("r-dt" ,r-dt) | |
7420 | ("r-gh" ,r-gh) | |
7421 | ("r-graph" ,r-graph) | |
7422 | ("r-htmltools" ,r-htmltools) | |
7423 | ("r-htmlwidgets" ,r-htmlwidgets) | |
7424 | ("r-httr" ,r-httr) | |
7425 | ("r-igraph" ,r-igraph) | |
7426 | ("r-jsonlite" ,r-jsonlite) | |
7427 | ("r-magrittr" ,r-magrittr) | |
2d6a7bca | 7428 | ("r-rappdirs" ,r-rappdirs) |
4a18112d RW |
7429 | ("r-rbgl" ,r-rbgl) |
7430 | ("r-readr" ,r-readr) | |
7431 | ("r-rex" ,r-rex) | |
2d6a7bca | 7432 | ("r-rlang" ,r-rlang) |
4a18112d RW |
7433 | ("r-rvest" ,r-rvest) |
7434 | ("r-stringr" ,r-stringr) | |
7435 | ("r-tibble" ,r-tibble) | |
7436 | ("r-tidyr" ,r-tidyr) | |
2d6a7bca | 7437 | ("r-tidyselect" ,r-tidyselect) |
4a18112d | 7438 | ("r-xml2" ,r-xml2))) |
2d6a7bca RW |
7439 | (native-inputs |
7440 | `(("r-knitr" ,r-knitr))) | |
4a18112d RW |
7441 | (home-page "https://github.com/seandavi/BiocPkgTools") |
7442 | (synopsis "Collection of tools for learning about Bioconductor packages") | |
7443 | (description | |
7444 | "Bioconductor has a rich ecosystem of metadata around packages, usage, | |
7445 | and build status. This package is a simple collection of functions to access | |
7446 | that metadata from R. The goal is to expose metadata for data mining and | |
7447 | value-added functionality such as package searching, text mining, and | |
7448 | analytics on packages.") | |
7449 | (license license:expat))) | |
43b66e3f RW |
7450 | |
7451 | (define-public r-biocset | |
7452 | (package | |
7453 | (name "r-biocset") | |
7454 | (version "1.0.1") | |
7455 | (source | |
7456 | (origin | |
7457 | (method url-fetch) | |
7458 | (uri (bioconductor-uri "BiocSet" version)) | |
7459 | (sha256 | |
7460 | (base32 | |
7461 | "1xcksnvjflrdarn8xqmgf0n6wbsjkq9jazqwp35i52vqcq4ic1j9")))) | |
7462 | (properties `((upstream-name . "BiocSet"))) | |
7463 | (build-system r-build-system) | |
7464 | (propagated-inputs | |
7465 | `(("r-annotationdbi" ,r-annotationdbi) | |
7466 | ("r-dplyr" ,r-dplyr) | |
7467 | ("r-keggrest" ,r-keggrest) | |
7468 | ("r-plyr" ,r-plyr) | |
7469 | ("r-rlang" ,r-rlang) | |
7470 | ("r-rtracklayer" ,r-rtracklayer) | |
7471 | ("r-tibble" ,r-tibble))) | |
7472 | (home-page | |
7473 | "https://bioconductor.org/packages/BiocSet") | |
7474 | (synopsis | |
7475 | "Representing Different Biological Sets") | |
7476 | (description | |
7477 | "BiocSet displays different biological sets in a triple tibble format. | |
7478 | These three tibbles are @code{element}, @code{set}, and @code{elementset}. | |
5b98473a | 7479 | The user has the ability to activate one of these three tibbles to perform |
43b66e3f RW |
7480 | common functions from the @code{dplyr} package. Mapping functionality and |
7481 | accessing web references for elements/sets are also available in BiocSet.") | |
7482 | (license license:artistic2.0))) | |
0156297f RW |
7483 | |
7484 | (define-public r-biocworkflowtools | |
7485 | (package | |
7486 | (name "r-biocworkflowtools") | |
7487 | (version "1.12.0") | |
7488 | (source | |
7489 | (origin | |
7490 | (method url-fetch) | |
7491 | (uri (bioconductor-uri "BiocWorkflowTools" version)) | |
7492 | (sha256 | |
7493 | (base32 | |
7494 | "1v4bhnpdkmllm7aghms9b7369hkrgz7mn69wbrqg1x42pgkf30ad")))) | |
7495 | (properties | |
7496 | `((upstream-name . "BiocWorkflowTools"))) | |
7497 | (build-system r-build-system) | |
7498 | (propagated-inputs | |
7499 | `(("r-biocstyle" ,r-biocstyle) | |
7500 | ("r-bookdown" ,r-bookdown) | |
7501 | ("r-git2r" ,r-git2r) | |
7502 | ("r-httr" ,r-httr) | |
7503 | ("r-knitr" ,r-knitr) | |
7504 | ("r-rmarkdown" ,r-rmarkdown) | |
7505 | ("r-rstudioapi" ,r-rstudioapi) | |
7506 | ("r-stringr" ,r-stringr) | |
7507 | ("r-usethis" ,r-usethis))) | |
7508 | (home-page "https://bioconductor.org/packages/BiocWorkflowTools/") | |
7509 | (synopsis "Tools to aid the development of Bioconductor Workflow packages") | |
7510 | (description | |
7511 | "This package provides functions to ease the transition between | |
7512 | Rmarkdown and LaTeX documents when authoring a Bioconductor Workflow.") | |
7513 | (license license:expat))) | |
77e2de36 RW |
7514 | |
7515 | (define-public r-biodist | |
7516 | (package | |
7517 | (name "r-biodist") | |
7518 | (version "1.58.0") | |
7519 | (source | |
7520 | (origin | |
7521 | (method url-fetch) | |
7522 | (uri (bioconductor-uri "bioDist" version)) | |
7523 | (sha256 | |
7524 | (base32 | |
7525 | "0iabw07px3ybdgbbab0vv350051cm4aq8w47rz9dnmzx4kil9h5q")))) | |
7526 | (properties `((upstream-name . "bioDist"))) | |
7527 | (build-system r-build-system) | |
7528 | (propagated-inputs | |
7529 | `(("r-biobase" ,r-biobase) | |
7530 | ("r-kernsmooth" ,r-kernsmooth))) | |
7531 | (home-page "https://bioconductor.org/packages/bioDist/") | |
7532 | (synopsis "Different distance measures") | |
7533 | (description | |
7534 | "This package provides a collection of software tools for calculating | |
7535 | distance measures.") | |
7536 | (license license:artistic2.0))) |