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fa596599 | 1 | ;;; GNU Guix --- Functional package management for GNU |
6aa896d8 RW |
2 | ;;; Copyright © 2016, 2017, 2018, 2019 Ricardo Wurmus <rekado@elephly.net> |
3 | ;;; Copyright © 2016, 2017, 2018 Roel Janssen <roel@gnu.org> | |
61242625 | 4 | ;;; Copyright © 2017, 2018, 2019 Tobias Geerinckx-Rice <me@tobias.gr> |
fa596599 RW |
5 | ;;; |
6 | ;;; This file is part of GNU Guix. | |
7 | ;;; | |
8 | ;;; GNU Guix is free software; you can redistribute it and/or modify it | |
9 | ;;; under the terms of the GNU General Public License as published by | |
10 | ;;; the Free Software Foundation; either version 3 of the License, or (at | |
11 | ;;; your option) any later version. | |
12 | ;;; | |
13 | ;;; GNU Guix is distributed in the hope that it will be useful, but | |
14 | ;;; WITHOUT ANY WARRANTY; without even the implied warranty of | |
15 | ;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the | |
16 | ;;; GNU General Public License for more details. | |
17 | ;;; | |
18 | ;;; You should have received a copy of the GNU General Public License | |
19 | ;;; along with GNU Guix. If not, see <http://www.gnu.org/licenses/>. | |
20 | ||
21 | (define-module (gnu packages bioconductor) | |
22 | #:use-module ((guix licenses) #:prefix license:) | |
23 | #:use-module (guix packages) | |
24 | #:use-module (guix download) | |
b2dce6b5 | 25 | #:use-module (guix git-download) |
fa596599 | 26 | #:use-module (guix build-system r) |
183ce988 | 27 | #:use-module (gnu packages) |
58656064 | 28 | #:use-module (gnu packages base) |
cf9a29b2 | 29 | #:use-module (gnu packages bioinformatics) |
a5b56a53 RJ |
30 | #:use-module (gnu packages cran) |
31 | #:use-module (gnu packages compression) | |
c18dccff | 32 | #:use-module (gnu packages gcc) |
cf9a29b2 | 33 | #:use-module (gnu packages graph) |
dddbc90c | 34 | #:use-module (gnu packages haskell-xyz) |
5cfa4bff | 35 | #:use-module (gnu packages image) |
b64ce4b7 | 36 | #:use-module (gnu packages maths) |
6b12f213 RW |
37 | #:use-module (gnu packages netpbm) |
38 | #:use-module (gnu packages perl) | |
2cb71d81 | 39 | #:use-module (gnu packages pkg-config) |
f4235c0e | 40 | #:use-module (gnu packages statistics) |
14bb1c48 RW |
41 | #:use-module (gnu packages web) |
42 | #:use-module (srfi srfi-1)) | |
fa596599 | 43 | |
557a1089 RW |
44 | \f |
45 | ;;; Annotations | |
46 | ||
b7d93cf5 RW |
47 | (define-public r-bsgenome-celegans-ucsc-ce6 |
48 | (package | |
49 | (name "r-bsgenome-celegans-ucsc-ce6") | |
50 | (version "1.4.0") | |
51 | (source (origin | |
52 | (method url-fetch) | |
86ced7b2 RW |
53 | (uri (bioconductor-uri "BSgenome.Celegans.UCSC.ce6" |
54 | version 'annotation)) | |
b7d93cf5 RW |
55 | (sha256 |
56 | (base32 | |
57 | "0mqzb353xv2c3m3vkb315dkmnxkgczp7ndnknyhpgjlybyf715v9")))) | |
58 | (properties | |
59 | `((upstream-name . "BSgenome.Celegans.UCSC.ce6"))) | |
60 | (build-system r-build-system) | |
b7d93cf5 RW |
61 | (propagated-inputs |
62 | `(("r-bsgenome" ,r-bsgenome))) | |
63 | (home-page | |
64 | "https://www.bioconductor.org/packages/BSgenome.Celegans.UCSC.ce6/") | |
65 | (synopsis "Full genome sequences for Worm") | |
66 | (description | |
67 | "This package provides full genome sequences for Caenorhabditis | |
68 | elegans (Worm) as provided by UCSC (ce6, May 2008) and stored in Biostrings | |
0c792ffb RW |
69 | objects.") |
70 | (license license:artistic2.0))) | |
71 | ||
72 | (define-public r-bsgenome-celegans-ucsc-ce10 | |
73 | (package | |
74 | (name "r-bsgenome-celegans-ucsc-ce10") | |
75 | (version "1.4.0") | |
76 | (source (origin | |
77 | (method url-fetch) | |
78 | ;; We cannot use bioconductor-uri here because this tarball is | |
79 | ;; located under "data/annotation/" instead of "bioc/". | |
80 | (uri (string-append "https://www.bioconductor.org/packages/" | |
81 | "release/data/annotation/src/contrib/" | |
82 | "BSgenome.Celegans.UCSC.ce10_" | |
83 | version ".tar.gz")) | |
84 | (sha256 | |
85 | (base32 | |
86 | "1zaym97jk4npxk14ifvwz2rvhm4zx9xgs33r9vvx9rlynp0gydrk")))) | |
87 | (properties | |
88 | `((upstream-name . "BSgenome.Celegans.UCSC.ce10"))) | |
89 | (build-system r-build-system) | |
90 | ;; As this package provides little more than a very large data file it | |
91 | ;; doesn't make sense to build substitutes. | |
92 | (arguments `(#:substitutable? #f)) | |
93 | (propagated-inputs | |
94 | `(("r-bsgenome" ,r-bsgenome))) | |
95 | (home-page | |
96 | "https://www.bioconductor.org/packages/BSgenome.Celegans.UCSC.ce10/") | |
97 | (synopsis "Full genome sequences for Worm") | |
98 | (description | |
99 | "This package provides full genome sequences for Caenorhabditis | |
100 | elegans (Worm) as provided by UCSC (ce10, Oct 2010) and stored in Biostrings | |
b7d93cf5 RW |
101 | objects.") |
102 | (license license:artistic2.0))) | |
103 | ||
183db725 RW |
104 | (define-public r-bsgenome-dmelanogaster-ucsc-dm6 |
105 | (package | |
106 | (name "r-bsgenome-dmelanogaster-ucsc-dm6") | |
107 | (version "1.4.1") | |
108 | (source (origin | |
109 | (method url-fetch) | |
110 | ;; We cannot use bioconductor-uri here because this tarball is | |
111 | ;; located under "data/annotation/" instead of "bioc/". | |
112 | (uri (string-append "https://www.bioconductor.org/packages/" | |
113 | "release/data/annotation/src/contrib/" | |
114 | "BSgenome.Dmelanogaster.UCSC.dm6_" | |
115 | version ".tar.gz")) | |
116 | (sha256 | |
117 | (base32 | |
118 | "1bhj0rdgf7lspw4xby9y9mf7v7jxxz8001bc8vw8kf04rjsx6060")))) | |
119 | (properties | |
120 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm6"))) | |
121 | (build-system r-build-system) | |
122 | ;; As this package provides little more than a very large data file it | |
123 | ;; doesn't make sense to build substitutes. | |
124 | (arguments `(#:substitutable? #f)) | |
125 | (propagated-inputs | |
126 | `(("r-bsgenome" ,r-bsgenome))) | |
127 | (home-page | |
128 | "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm6/") | |
129 | (synopsis "Full genome sequences for Fly") | |
130 | (description | |
131 | "This package provides full genome sequences for Drosophila | |
132 | melanogaster (Fly) as provided by UCSC (dm6) and stored in Biostrings | |
133 | objects.") | |
134 | (license license:artistic2.0))) | |
135 | ||
13dabd69 RW |
136 | (define-public r-bsgenome-dmelanogaster-ucsc-dm3 |
137 | (package | |
138 | (name "r-bsgenome-dmelanogaster-ucsc-dm3") | |
139 | (version "1.4.0") | |
140 | (source (origin | |
141 | (method url-fetch) | |
142 | ;; We cannot use bioconductor-uri here because this tarball is | |
143 | ;; located under "data/annotation/" instead of "bioc/". | |
144 | (uri (string-append "https://www.bioconductor.org/packages/" | |
145 | "release/data/annotation/src/contrib/" | |
146 | "BSgenome.Dmelanogaster.UCSC.dm3_" | |
147 | version ".tar.gz")) | |
148 | (sha256 | |
149 | (base32 | |
150 | "19bm3lkhhkag3gnwp419211fh0cnr0x6fa0r1lr0ycwrikxdxsv8")))) | |
151 | (properties | |
152 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm3"))) | |
153 | (build-system r-build-system) | |
154 | ;; As this package provides little more than a very large data file it | |
155 | ;; doesn't make sense to build substitutes. | |
156 | (arguments `(#:substitutable? #f)) | |
157 | (propagated-inputs | |
158 | `(("r-bsgenome" ,r-bsgenome))) | |
159 | (home-page | |
160 | "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm3/") | |
161 | (synopsis "Full genome sequences for Fly") | |
162 | (description | |
163 | "This package provides full genome sequences for Drosophila | |
164 | melanogaster (Fly) as provided by UCSC (dm3, April 2006) and stored in | |
165 | Biostrings objects.") | |
166 | (license license:artistic2.0))) | |
167 | ||
dfac7eb9 RW |
168 | (define-public r-bsgenome-dmelanogaster-ucsc-dm3-masked |
169 | (package | |
170 | (name "r-bsgenome-dmelanogaster-ucsc-dm3-masked") | |
171 | (version "1.3.99") | |
172 | (source (origin | |
173 | (method url-fetch) | |
174 | ;; We cannot use bioconductor-uri here because this tarball is | |
175 | ;; located under "data/annotation/" instead of "bioc/". | |
176 | (uri (string-append "http://www.bioconductor.org/packages/" | |
177 | "release/data/annotation/src/contrib/" | |
178 | "BSgenome.Dmelanogaster.UCSC.dm3.masked_" | |
179 | version ".tar.gz")) | |
180 | (sha256 | |
181 | (base32 | |
182 | "1756csb09f1br9rj1l3f08qyh4hlymdbd0cfn8x3fq39dn45m5ap")))) | |
183 | (properties | |
184 | `((upstream-name . "BSgenome.Dmelanogaster.UCSC.dm3.masked"))) | |
185 | (build-system r-build-system) | |
186 | (propagated-inputs | |
187 | `(("r-bsgenome" ,r-bsgenome) | |
188 | ("r-bsgenome-dmelanogaster-ucsc-dm3" | |
189 | ,r-bsgenome-dmelanogaster-ucsc-dm3))) | |
190 | (home-page "https://www.bioconductor.org/packages/BSgenome.Dmelanogaster.UCSC.dm3.masked/") | |
191 | (synopsis "Full masked genome sequences for Fly") | |
192 | (description | |
193 | "This package provides full masked genome sequences for Drosophila | |
194 | melanogaster (Fly) as provided by UCSC (dm3, April 2006) and stored in | |
195 | Biostrings objects. The sequences are the same as in | |
196 | BSgenome.Dmelanogaster.UCSC.dm3, except that each of them has the 4 following | |
197 | masks on top: (1) the mask of assembly gaps (AGAPS mask), (2) the mask of | |
198 | intra-contig ambiguities (AMB mask), (3) the mask of repeats from | |
199 | RepeatMasker (RM mask), and (4) the mask of repeats from Tandem Repeats | |
200 | Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by default.") | |
201 | (license license:artistic2.0))) | |
202 | ||
40a65057 RW |
203 | (define-public r-bsgenome-hsapiens-1000genomes-hs37d5 |
204 | (package | |
205 | (name "r-bsgenome-hsapiens-1000genomes-hs37d5") | |
206 | (version "0.99.1") | |
207 | (source (origin | |
208 | (method url-fetch) | |
209 | ;; We cannot use bioconductor-uri here because this tarball is | |
210 | ;; located under "data/annotation/" instead of "bioc/". | |
211 | (uri (string-append "https://www.bioconductor.org/packages/" | |
212 | "release/data/annotation/src/contrib/" | |
213 | "BSgenome.Hsapiens.1000genomes.hs37d5_" | |
214 | version ".tar.gz")) | |
215 | (sha256 | |
216 | (base32 | |
217 | "1cg0g5fqmsvwyw2p9hp2yy4ilk21jkbbrnpgqvb5c36ihjwvc7sr")))) | |
218 | (properties | |
219 | `((upstream-name . "BSgenome.Hsapiens.1000genomes.hs37d5"))) | |
220 | (build-system r-build-system) | |
221 | ;; As this package provides little more than a very large data file it | |
222 | ;; doesn't make sense to build substitutes. | |
223 | (arguments `(#:substitutable? #f)) | |
224 | (propagated-inputs | |
225 | `(("r-bsgenome" ,r-bsgenome))) | |
226 | (home-page | |
227 | "https://www.bioconductor.org/packages/BSgenome.Hsapiens.1000genomes.hs37d5/") | |
228 | (synopsis "Full genome sequences for Homo sapiens") | |
229 | (description | |
230 | "This package provides full genome sequences for Homo sapiens from | |
231 | 1000genomes phase2 reference genome sequence (hs37d5), based on NCBI GRCh37.") | |
232 | (license license:artistic2.0))) | |
233 | ||
6fbd759b RW |
234 | (define-public r-bsgenome-hsapiens-ucsc-hg19-masked |
235 | (package | |
236 | (name "r-bsgenome-hsapiens-ucsc-hg19-masked") | |
237 | (version "1.3.99") | |
238 | (source (origin | |
239 | (method url-fetch) | |
240 | ;; We cannot use bioconductor-uri here because this tarball is | |
241 | ;; located under "data/annotation/" instead of "bioc/". | |
242 | (uri (string-append "http://www.bioconductor.org/packages/" | |
243 | "release/data/annotation/src/contrib/" | |
244 | "BSgenome.Hsapiens.UCSC.hg19.masked_" | |
245 | version ".tar.gz")) | |
246 | (sha256 | |
247 | (base32 | |
248 | "0452pyah0kv1vsrsjbrqw4k2rm8lc2vc771dzib45gnnfz86qxrr")))) | |
249 | (properties | |
250 | `((upstream-name . "BSgenome.Hsapiens.UCSC.hg19.masked"))) | |
251 | (build-system r-build-system) | |
252 | (propagated-inputs | |
253 | `(("r-bsgenome" ,r-bsgenome) | |
254 | ("r-bsgenome-hsapiens-ucsc-hg19" | |
255 | ,r-bsgenome-hsapiens-ucsc-hg19))) | |
256 | (home-page "https://bioconductor.org/packages/BSgenome.Hsapiens.UCSC.hg19.masked/") | |
257 | (synopsis "Full masked genome sequences for Homo sapiens") | |
258 | (description | |
259 | "This package provides full genome sequences for Homo sapiens (Human) as | |
260 | provided by UCSC (hg19, Feb. 2009) and stored in Biostrings objects. The | |
261 | sequences are the same as in BSgenome.Hsapiens.UCSC.hg19, except that each of | |
262 | them has the 4 following masks on top: (1) the mask of assembly gaps (AGAPS | |
263 | mask), (2) the mask of intra-contig ambiguities (AMB mask), (3) the mask of | |
264 | repeats from RepeatMasker (RM mask), and (4) the mask of repeats from Tandem | |
265 | Repeats Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by | |
266 | default.") | |
267 | (license license:artistic2.0))) | |
268 | ||
5acb9052 RW |
269 | (define-public r-bsgenome-mmusculus-ucsc-mm9 |
270 | (package | |
271 | (name "r-bsgenome-mmusculus-ucsc-mm9") | |
272 | (version "1.4.0") | |
273 | (source (origin | |
274 | (method url-fetch) | |
275 | ;; We cannot use bioconductor-uri here because this tarball is | |
276 | ;; located under "data/annotation/" instead of "bioc/". | |
277 | (uri (string-append "https://www.bioconductor.org/packages/" | |
278 | "release/data/annotation/src/contrib/" | |
279 | "BSgenome.Mmusculus.UCSC.mm9_" | |
280 | version ".tar.gz")) | |
281 | (sha256 | |
282 | (base32 | |
283 | "1birqw30g2azimxpnjfzmkphan7x131yy8b9h85lfz5fjdg7841i")))) | |
284 | (properties | |
285 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm9"))) | |
286 | (build-system r-build-system) | |
287 | ;; As this package provides little more than a very large data file it | |
288 | ;; doesn't make sense to build substitutes. | |
289 | (arguments `(#:substitutable? #f)) | |
290 | (propagated-inputs | |
291 | `(("r-bsgenome" ,r-bsgenome))) | |
292 | (home-page | |
293 | "https://www.bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9/") | |
294 | (synopsis "Full genome sequences for Mouse") | |
295 | (description | |
296 | "This package provides full genome sequences for Mus musculus (Mouse) as | |
297 | provided by UCSC (mm9, July 2007) and stored in Biostrings objects.") | |
298 | (license license:artistic2.0))) | |
299 | ||
2bece692 RW |
300 | (define-public r-bsgenome-mmusculus-ucsc-mm9-masked |
301 | (package | |
302 | (name "r-bsgenome-mmusculus-ucsc-mm9-masked") | |
303 | (version "1.3.99") | |
304 | (source (origin | |
305 | (method url-fetch) | |
306 | ;; We cannot use bioconductor-uri here because this tarball is | |
307 | ;; located under "data/annotation/" instead of "bioc/". | |
308 | (uri (string-append "http://www.bioconductor.org/packages/" | |
309 | "release/data/annotation/src/contrib/" | |
310 | "BSgenome.Mmusculus.UCSC.mm9.masked_" | |
311 | version ".tar.gz")) | |
312 | (sha256 | |
313 | (base32 | |
314 | "00bpbm3havqcxr4g63zhllsbpd9q6svgihks7qp7x73nm4gvq7fn")))) | |
315 | (properties | |
316 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm9.masked"))) | |
317 | (build-system r-build-system) | |
318 | (propagated-inputs | |
319 | `(("r-bsgenome" ,r-bsgenome) | |
320 | ("r-bsgenome-mmusculus-ucsc-mm9" | |
321 | ,r-bsgenome-mmusculus-ucsc-mm9))) | |
322 | (home-page "http://bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9.masked/") | |
323 | (synopsis "Full masked genome sequences for Mouse") | |
324 | (description | |
325 | "This package provides full genome sequences for Mus musculus (Mouse) as | |
326 | provided by UCSC (mm9, Jul. 2007) and stored in Biostrings objects. The | |
327 | sequences are the same as in BSgenome.Mmusculus.UCSC.mm9, except that each of | |
328 | them has the 4 following masks on top: (1) the mask of assembly gaps (AGAPS | |
329 | mask), (2) the mask of intra-contig ambiguities (AMB mask), (3) the mask of | |
330 | repeats from RepeatMasker (RM mask), and (4) the mask of repeats from Tandem | |
331 | Repeats Finder (TRF mask). Only the AGAPS and AMB masks are \"active\" by | |
332 | default." ) | |
333 | (license license:artistic2.0))) | |
334 | ||
c3adc830 RW |
335 | (define-public r-bsgenome-mmusculus-ucsc-mm10 |
336 | (package | |
337 | (name "r-bsgenome-mmusculus-ucsc-mm10") | |
338 | (version "1.4.0") | |
339 | (source (origin | |
340 | (method url-fetch) | |
341 | ;; We cannot use bioconductor-uri here because this tarball is | |
342 | ;; located under "data/annotation/" instead of "bioc/". | |
343 | (uri (string-append "https://www.bioconductor.org/packages/" | |
344 | "release/data/annotation/src/contrib/" | |
345 | "BSgenome.Mmusculus.UCSC.mm10_" | |
346 | version ".tar.gz")) | |
347 | (sha256 | |
348 | (base32 | |
349 | "12s0nm2na9brjad4rn9l7d3db2aj8qa1xvz0y1k7gk08wayb6bkf")))) | |
350 | (properties | |
351 | `((upstream-name . "BSgenome.Mmusculus.UCSC.mm10"))) | |
352 | (build-system r-build-system) | |
353 | ;; As this package provides little more than a very large data file it | |
354 | ;; doesn't make sense to build substitutes. | |
355 | (arguments `(#:substitutable? #f)) | |
356 | (propagated-inputs | |
357 | `(("r-bsgenome" ,r-bsgenome))) | |
358 | (home-page | |
359 | "https://www.bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm10/") | |
360 | (synopsis "Full genome sequences for Mouse") | |
361 | (description | |
362 | "This package provides full genome sequences for Mus | |
363 | musculus (Mouse) as provided by UCSC (mm10, December 2011) and stored | |
364 | in Biostrings objects.") | |
365 | (license license:artistic2.0))) | |
366 | ||
3a08940e RW |
367 | (define-public r-org-ce-eg-db |
368 | (package | |
369 | (name "r-org-ce-eg-db") | |
370 | (version "3.7.0") | |
371 | (source (origin | |
372 | (method url-fetch) | |
373 | ;; We cannot use bioconductor-uri here because this tarball is | |
374 | ;; located under "data/annotation/" instead of "bioc/". | |
375 | (uri (string-append "https://www.bioconductor.org/packages/" | |
376 | "release/data/annotation/src/contrib/" | |
377 | "org.Ce.eg.db_" version ".tar.gz")) | |
378 | (sha256 | |
379 | (base32 | |
380 | "1w5br1ss4ha8wv4v2saj7cmbjc2jw0dyj2f2y269l078z31wcnaz")))) | |
381 | (properties | |
382 | `((upstream-name . "org.Ce.eg.db"))) | |
383 | (build-system r-build-system) | |
384 | (propagated-inputs | |
385 | `(("r-annotationdbi" ,r-annotationdbi))) | |
386 | (home-page "https://www.bioconductor.org/packages/org.Ce.eg.db/") | |
387 | (synopsis "Genome wide annotation for Worm") | |
388 | (description | |
389 | "This package provides mappings from Entrez gene identifiers to various | |
390 | annotations for the genome of the model worm Caenorhabditis elegans.") | |
391 | (license license:artistic2.0))) | |
392 | ||
f8780e96 RW |
393 | (define-public r-org-dm-eg-db |
394 | (package | |
395 | (name "r-org-dm-eg-db") | |
396 | (version "3.7.0") | |
397 | (source (origin | |
398 | (method url-fetch) | |
399 | ;; We cannot use bioconductor-uri here because this tarball is | |
400 | ;; located under "data/annotation/" instead of "bioc/". | |
401 | (uri (string-append "https://www.bioconductor.org/packages/" | |
402 | "release/data/annotation/src/contrib/" | |
403 | "org.Dm.eg.db_" version ".tar.gz")) | |
404 | (sha256 | |
405 | (base32 | |
406 | "1pqjrzlyg72bjpy8zsxvaglc7jsv176bnyi87xdajmkvsgxpm7b3")))) | |
407 | (properties | |
408 | `((upstream-name . "org.Dm.eg.db"))) | |
409 | (build-system r-build-system) | |
410 | (propagated-inputs | |
411 | `(("r-annotationdbi" ,r-annotationdbi))) | |
412 | (home-page "https://www.bioconductor.org/packages/org.Dm.eg.db/") | |
413 | (synopsis "Genome wide annotation for Fly") | |
414 | (description | |
415 | "This package provides mappings from Entrez gene identifiers to various | |
416 | annotations for the genome of the model fruit fly Drosophila melanogaster.") | |
417 | (license license:artistic2.0))) | |
418 | ||
3dad6087 RW |
419 | (define-public r-org-dr-eg-db |
420 | (package | |
421 | (name "r-org-dr-eg-db") | |
422 | (version "3.7.0") | |
423 | (source (origin | |
424 | (method url-fetch) | |
425 | ;; We cannot use bioconductor-uri here because this tarball is | |
426 | ;; located under "data/annotation/" instead of "bioc/". | |
427 | (uri (string-append "https://www.bioconductor.org/packages/" | |
428 | "release/data/annotation/src/contrib/" | |
429 | "org.Dr.eg.db_" version ".tar.gz")) | |
430 | (sha256 | |
431 | (base32 | |
432 | "1xs5wsbcpy0iwbjyiv7fax57djqc529ai5fk1qfsdcvlja3cpglx")))) | |
433 | (properties | |
434 | `((upstream-name . "org.Dr.eg.db"))) | |
435 | (build-system r-build-system) | |
436 | (propagated-inputs | |
437 | `(("r-annotationdbi" ,r-annotationdbi))) | |
438 | (home-page "https://www.bioconductor.org/packages/org.Dr.eg.db/") | |
439 | (synopsis "Annotation for Zebrafish") | |
440 | (description | |
441 | "This package provides genome wide annotations for Zebrafish, primarily | |
442 | based on mapping using Entrez Gene identifiers.") | |
443 | (license license:artistic2.0))) | |
444 | ||
d56df35a RW |
445 | (define-public r-org-hs-eg-db |
446 | (package | |
447 | (name "r-org-hs-eg-db") | |
448 | (version "3.7.0") | |
449 | (source (origin | |
450 | (method url-fetch) | |
451 | ;; We cannot use bioconductor-uri here because this tarball is | |
452 | ;; located under "data/annotation/" instead of "bioc/". | |
453 | (uri (string-append "https://www.bioconductor.org/packages/" | |
454 | "release/data/annotation/src/contrib/" | |
455 | "org.Hs.eg.db_" version ".tar.gz")) | |
456 | (sha256 | |
457 | (base32 | |
458 | "1qxz9l80yg3qdqszs6dsscp7lrpfi1bgd0pxh9j7q34vprzwhdim")))) | |
459 | (properties | |
460 | `((upstream-name . "org.Hs.eg.db"))) | |
461 | (build-system r-build-system) | |
462 | (propagated-inputs | |
463 | `(("r-annotationdbi" ,r-annotationdbi))) | |
464 | (home-page "https://www.bioconductor.org/packages/org.Hs.eg.db/") | |
465 | (synopsis "Genome wide annotation for Human") | |
466 | (description | |
467 | "This package contains genome-wide annotations for Human, primarily based | |
468 | on mapping using Entrez Gene identifiers.") | |
469 | (license license:artistic2.0))) | |
470 | ||
8035819f RW |
471 | (define-public r-org-mm-eg-db |
472 | (package | |
473 | (name "r-org-mm-eg-db") | |
474 | (version "3.7.0") | |
475 | (source (origin | |
476 | (method url-fetch) | |
477 | ;; We cannot use bioconductor-uri here because this tarball is | |
478 | ;; located under "data/annotation/" instead of "bioc/". | |
479 | (uri (string-append "https://www.bioconductor.org/packages/" | |
480 | "release/data/annotation/src/contrib/" | |
481 | "org.Mm.eg.db_" version ".tar.gz")) | |
482 | (sha256 | |
483 | (base32 | |
484 | "1i3nvrd3wjigf1rmgxq1p5xxc3p8v02h5gwi62s30rkrsyjjfjxx")))) | |
485 | (properties | |
486 | `((upstream-name . "org.Mm.eg.db"))) | |
487 | (build-system r-build-system) | |
488 | (propagated-inputs | |
489 | `(("r-annotationdbi" ,r-annotationdbi))) | |
490 | (home-page "https://www.bioconductor.org/packages/org.Mm.eg.db/") | |
491 | (synopsis "Genome wide annotation for Mouse") | |
492 | (description | |
493 | "This package provides mappings from Entrez gene identifiers to various | |
494 | annotations for the genome of the model mouse Mus musculus.") | |
495 | (license license:artistic2.0))) | |
496 | ||
fe0b76e2 RW |
497 | (define-public r-bsgenome-hsapiens-ucsc-hg19 |
498 | (package | |
499 | (name "r-bsgenome-hsapiens-ucsc-hg19") | |
500 | (version "1.4.0") | |
501 | (source (origin | |
502 | (method url-fetch) | |
503 | ;; We cannot use bioconductor-uri here because this tarball is | |
504 | ;; located under "data/annotation/" instead of "bioc/". | |
505 | (uri (string-append "https://www.bioconductor.org/packages/" | |
506 | "release/data/annotation/src/contrib/" | |
507 | "BSgenome.Hsapiens.UCSC.hg19_" | |
508 | version ".tar.gz")) | |
509 | (sha256 | |
510 | (base32 | |
511 | "1y0nqpk8cw5a34sd9hmin3z4v7iqm6hf6l22cl81vlbxqbjibxc8")))) | |
512 | (properties | |
513 | `((upstream-name . "BSgenome.Hsapiens.UCSC.hg19"))) | |
514 | (build-system r-build-system) | |
515 | ;; As this package provides little more than a very large data file it | |
516 | ;; doesn't make sense to build substitutes. | |
517 | (arguments `(#:substitutable? #f)) | |
518 | (propagated-inputs | |
519 | `(("r-bsgenome" ,r-bsgenome))) | |
520 | (home-page | |
521 | "https://www.bioconductor.org/packages/BSgenome.Hsapiens.UCSC.hg19/") | |
522 | (synopsis "Full genome sequences for Homo sapiens") | |
523 | (description | |
524 | "This package provides full genome sequences for Homo sapiens as provided | |
525 | by UCSC (hg19, February 2009) and stored in Biostrings objects.") | |
526 | (license license:artistic2.0))) | |
527 | ||
8324e64c RW |
528 | (define-public r-ensdb-hsapiens-v75 |
529 | (package | |
530 | (name "r-ensdb-hsapiens-v75") | |
531 | (version "2.99.0") | |
532 | (source | |
533 | (origin | |
534 | (method url-fetch) | |
535 | (uri (bioconductor-uri "EnsDb.Hsapiens.v75" version 'annotation)) | |
536 | (sha256 | |
537 | (base32 | |
538 | "0jx6rf6v0j8yr07q3c1h7s121901dc400nm6xaiv4i7kb5czjn9c")))) | |
539 | (properties | |
540 | `((upstream-name . "EnsDb.Hsapiens.v75"))) | |
541 | (build-system r-build-system) | |
542 | (propagated-inputs | |
543 | `(("r-ensembldb" ,r-ensembldb))) | |
544 | (home-page "https://bioconductor.org/packages/EnsDb.Hsapiens.v75") | |
545 | (synopsis "Ensembl based annotation package") | |
546 | (description | |
547 | "This package exposes an annotation database generated from Ensembl.") | |
548 | (license license:artistic2.0))) | |
549 | ||
2cc51108 RW |
550 | (define-public r-genelendatabase |
551 | (package | |
552 | (name "r-genelendatabase") | |
daeb3cd9 | 553 | (version "1.18.0") |
2cc51108 RW |
554 | (source |
555 | (origin | |
556 | (method url-fetch) | |
557 | ;; We cannot use bioconductor-uri here because this tarball is | |
558 | ;; located under "data/experiment/" instead of "bioc/". | |
559 | (uri (string-append "https://bioconductor.org/packages/" | |
560 | "release/data/experiment/src/contrib" | |
561 | "/geneLenDataBase_" version ".tar.gz")) | |
562 | (sha256 | |
563 | (base32 | |
daeb3cd9 | 564 | "03gm4pvsfascx7kjg0jycpf4f572mja68wwmwigs390vbmawyb4a")))) |
2cc51108 RW |
565 | (properties |
566 | `((upstream-name . "geneLenDataBase"))) | |
567 | (build-system r-build-system) | |
568 | (propagated-inputs | |
569 | `(("r-rtracklayer" ,r-rtracklayer) | |
570 | ("r-genomicfeatures" ,r-genomicfeatures))) | |
571 | (home-page "https://bioconductor.org/packages/geneLenDataBase/") | |
572 | (synopsis "Lengths of mRNA transcripts for a number of genomes") | |
573 | (description | |
574 | "This package provides the lengths of mRNA transcripts for a number of | |
575 | genomes and gene ID formats, largely based on the UCSC table browser.") | |
576 | (license license:lgpl2.0+))) | |
577 | ||
66e35ce6 RW |
578 | (define-public r-txdb-hsapiens-ucsc-hg19-knowngene |
579 | (package | |
580 | (name "r-txdb-hsapiens-ucsc-hg19-knowngene") | |
581 | (version "3.2.2") | |
582 | (source (origin | |
583 | (method url-fetch) | |
584 | ;; We cannot use bioconductor-uri here because this tarball is | |
585 | ;; located under "data/annotation/" instead of "bioc/". | |
586 | (uri (string-append "https://bioconductor.org/packages/" | |
587 | "release/data/annotation/src/contrib" | |
588 | "/TxDb.Hsapiens.UCSC.hg19.knownGene_" | |
589 | version ".tar.gz")) | |
590 | (sha256 | |
591 | (base32 | |
592 | "1sajhcqqwazgz2lqbik7rd935i7kpnh08zxbp2ra10j72yqy4g86")))) | |
593 | (properties | |
594 | `((upstream-name . "TxDb.Hsapiens.UCSC.hg19.knownGene"))) | |
595 | (build-system r-build-system) | |
596 | ;; As this package provides little more than a very large data file it | |
597 | ;; doesn't make sense to build substitutes. | |
598 | (arguments `(#:substitutable? #f)) | |
599 | (propagated-inputs | |
600 | `(("r-genomicfeatures" ,r-genomicfeatures))) | |
601 | (home-page | |
602 | "https://bioconductor.org/packages/TxDb.Hsapiens.UCSC.hg19.knownGene/") | |
603 | (synopsis "Annotation package for human genome in TxDb format") | |
604 | (description | |
605 | "This package provides an annotation database of Homo sapiens genome | |
606 | data. It is derived from the UCSC hg19 genome and based on the \"knownGene\" | |
798b80ce RW |
607 | track. The database is exposed as a @code{TxDb} object.") |
608 | (license license:artistic2.0))) | |
609 | ||
610 | (define-public r-txdb-hsapiens-ucsc-hg38-knowngene | |
611 | (package | |
612 | (name "r-txdb-hsapiens-ucsc-hg38-knowngene") | |
613 | (version "3.4.6") | |
614 | (source (origin | |
615 | (method url-fetch) | |
616 | ;; We cannot use bioconductor-uri here because this tarball is | |
617 | ;; located under "data/annotation/" instead of "bioc/". | |
618 | (uri (string-append "https://bioconductor.org/packages/" | |
619 | "release/data/annotation/src/contrib" | |
620 | "/TxDb.Hsapiens.UCSC.hg38.knownGene_" | |
621 | version ".tar.gz")) | |
622 | (sha256 | |
623 | (base32 | |
624 | "12j7rri9r129v9w1yiqadg952dx462dh092sxif3r5kk8l7bxkn9")))) | |
625 | (properties | |
626 | `((upstream-name . "TxDb.Hsapiens.UCSC.hg38.knownGene"))) | |
627 | (build-system r-build-system) | |
628 | (propagated-inputs | |
629 | `(("r-genomicfeatures" ,r-genomicfeatures))) | |
630 | (home-page | |
631 | "https://bioconductor.org/packages/TxDb.Hsapiens.UCSC.hg38.knownGene/") | |
632 | (synopsis "Annotation package for human genome in TxDb format") | |
633 | (description | |
634 | "This package provides an annotation database of Homo sapiens genome | |
635 | data. It is derived from the UCSC hg38 genome and based on the \"knownGene\" | |
66e35ce6 RW |
636 | track. The database is exposed as a @code{TxDb} object.") |
637 | (license license:artistic2.0))) | |
638 | ||
d220babf RW |
639 | (define-public r-txdb-mmusculus-ucsc-mm9-knowngene |
640 | (package | |
641 | (name "r-txdb-mmusculus-ucsc-mm9-knowngene") | |
642 | (version "3.2.2") | |
643 | (source (origin | |
644 | (method url-fetch) | |
645 | ;; We cannot use bioconductor-uri here because this tarball is | |
646 | ;; located under "data/annotation/" instead of "bioc/". | |
647 | (uri (string-append "https://bioconductor.org/packages/" | |
648 | "release/data/annotation/src/contrib" | |
649 | "/TxDb.Mmusculus.UCSC.mm9.knownGene_" | |
650 | version ".tar.gz")) | |
651 | (sha256 | |
652 | (base32 | |
653 | "16bjxy00363hf91ik2mqlqls86i07gia72qh92xc3l1ncch61mx2")))) | |
654 | (properties | |
655 | `((upstream-name . "TxDb.Mmusculus.UCSC.mm9.knownGene"))) | |
656 | (build-system r-build-system) | |
657 | (propagated-inputs | |
658 | `(("r-genomicfeatures" ,r-genomicfeatures) | |
659 | ("r-annotationdbi" ,r-annotationdbi))) | |
660 | (home-page | |
661 | "https://bioconductor.org/packages/TxDb.Mmusculus.UCSC.mm9.knownGene/") | |
662 | (synopsis "Annotation package for mouse genome in TxDb format") | |
663 | (description | |
664 | "This package provides an annotation database of Mouse genome data. It | |
665 | is derived from the UCSC mm9 genome and based on the \"knownGene\" track. The | |
666 | database is exposed as a @code{TxDb} object.") | |
667 | (license license:artistic2.0))) | |
668 | ||
7bc5d1b0 RW |
669 | (define-public r-txdb-mmusculus-ucsc-mm10-knowngene |
670 | (package | |
671 | (name "r-txdb-mmusculus-ucsc-mm10-knowngene") | |
61242625 | 672 | (version "3.4.7") |
7bc5d1b0 RW |
673 | (source (origin |
674 | (method url-fetch) | |
675 | ;; We cannot use bioconductor-uri here because this tarball is | |
676 | ;; located under "data/annotation/" instead of "bioc/". | |
677 | (uri (string-append "https://www.bioconductor.org/packages/" | |
678 | "release/data/annotation/src/contrib/" | |
679 | "TxDb.Mmusculus.UCSC.mm10.knownGene_" | |
680 | version ".tar.gz")) | |
681 | (sha256 | |
682 | (base32 | |
61242625 | 683 | "04impkl8zh1gpwwrpbf19jqznsjrq2306yyhm6cmx6hr1401bd6b")))) |
7bc5d1b0 RW |
684 | (properties |
685 | `((upstream-name . "TxDb.Mmusculus.UCSC.mm10.knownGene"))) | |
686 | (build-system r-build-system) | |
687 | ;; As this package provides little more than a very large data file it | |
688 | ;; doesn't make sense to build substitutes. | |
689 | (arguments `(#:substitutable? #f)) | |
690 | (propagated-inputs | |
691 | `(("r-bsgenome" ,r-bsgenome) | |
692 | ("r-genomicfeatures" ,r-genomicfeatures) | |
693 | ("r-annotationdbi" ,r-annotationdbi))) | |
694 | (home-page | |
695 | "https://bioconductor.org/packages/TxDb.Mmusculus.UCSC.mm10.knownGene/") | |
696 | (synopsis "Annotation package for TxDb knownGene object(s) for Mouse") | |
697 | (description | |
698 | "This package loads a TxDb object, which is an R interface to | |
699 | prefabricated databases contained in this package. This package provides | |
700 | the TxDb object of Mouse data as provided by UCSC (mm10, December 2011) | |
701 | based on the knownGene track.") | |
702 | (license license:artistic2.0))) | |
703 | ||
7cd446fd RW |
704 | (define-public r-txdb-celegans-ucsc-ce6-ensgene |
705 | (package | |
706 | (name "r-txdb-celegans-ucsc-ce6-ensgene") | |
707 | (version "3.2.2") | |
708 | (source | |
709 | (origin | |
710 | (method url-fetch) | |
711 | (uri (bioconductor-uri "TxDb.Celegans.UCSC.ce6.ensGene" | |
712 | version 'annotation)) | |
713 | (sha256 | |
714 | (base32 | |
715 | "1sgppva33cdy4isj2is8mfalj5gmmkpbkq9w1d83a4agcq31mi90")))) | |
716 | (properties | |
717 | `((upstream-name . "TxDb.Celegans.UCSC.ce6.ensGene"))) | |
718 | (build-system r-build-system) | |
719 | (propagated-inputs | |
720 | `(("r-annotationdbi" ,r-annotationdbi) | |
721 | ("r-genomicfeatures" ,r-genomicfeatures))) | |
722 | (home-page "https://bioconductor.org/packages/TxDb.Celegans.UCSC.ce6.ensGene/") | |
723 | (synopsis "Annotation package for C elegans TxDb objects") | |
724 | (description | |
725 | "This package exposes a C elegans annotation database generated from UCSC | |
726 | by exposing these as TxDb objects.") | |
727 | (license license:artistic2.0))) | |
728 | ||
0f5c9cec RW |
729 | (define-public r-fdb-infiniummethylation-hg19 |
730 | (package | |
731 | (name "r-fdb-infiniummethylation-hg19") | |
732 | (version "2.2.0") | |
733 | (source (origin | |
734 | (method url-fetch) | |
735 | ;; We cannot use bioconductor-uri here because this tarball is | |
736 | ;; located under "data/annotation/" instead of "bioc/". | |
737 | (uri (string-append "https://www.bioconductor.org/packages/" | |
738 | "release/data/annotation/src/contrib/" | |
739 | "FDb.InfiniumMethylation.hg19_" | |
740 | version ".tar.gz")) | |
741 | (sha256 | |
742 | (base32 | |
743 | "0gq90fvph6kgrpjb89nvzq6hl1k24swn19rgjh5g98l86mja6nk0")))) | |
744 | (properties | |
745 | `((upstream-name . "FDb.InfiniumMethylation.hg19"))) | |
746 | (build-system r-build-system) | |
747 | (propagated-inputs | |
748 | `(("r-biostrings" ,r-biostrings) | |
749 | ("r-genomicfeatures" ,r-genomicfeatures) | |
750 | ("r-annotationdbi" ,r-annotationdbi) | |
751 | ("r-org-hs-eg-db" ,r-org-hs-eg-db) | |
752 | ("r-txdb-hsapiens-ucsc-hg19-knowngene" ,r-txdb-hsapiens-ucsc-hg19-knowngene))) | |
753 | (home-page "https://bioconductor.org/packages/FDb.InfiniumMethylation.hg19/") | |
754 | (synopsis "Compiled HumanMethylation27 and HumanMethylation450 annotations") | |
755 | (description | |
756 | "This is an annotation package for Illumina Infinium DNA methylation | |
757 | probes. It contains the compiled HumanMethylation27 and HumanMethylation450 | |
758 | annotations.") | |
759 | (license license:artistic2.0))) | |
760 | ||
9475a248 RW |
761 | (define-public r-illuminahumanmethylationepicmanifest |
762 | (package | |
763 | (name "r-illuminahumanmethylationepicmanifest") | |
764 | (version "0.3.0") | |
765 | (source (origin | |
766 | (method url-fetch) | |
767 | ;; We cannot use bioconductor-uri here because this tarball is | |
768 | ;; located under "data/annotation/" instead of "bioc/". | |
769 | (uri (string-append "https://www.bioconductor.org/packages/" | |
770 | "release/data/annotation/src/contrib/" | |
771 | "IlluminaHumanMethylationEPICmanifest_" | |
772 | version ".tar.gz")) | |
773 | (sha256 | |
774 | (base32 | |
775 | "0alhjda5g186z8b1nsmnpfswrlj7prdz8mkwx60wkkl6hkcnk6p3")))) | |
776 | (properties | |
777 | `((upstream-name . "IlluminaHumanMethylationEPICmanifest"))) | |
778 | (build-system r-build-system) | |
779 | (propagated-inputs | |
780 | `(("r-minfi" ,r-minfi))) | |
781 | (home-page "https://bioconductor.org/packages/IlluminaHumanMethylationEPICmanifest/") | |
782 | (synopsis "Manifest for Illumina's EPIC methylation arrays") | |
783 | (description | |
784 | "This is a manifest package for Illumina's EPIC methylation arrays.") | |
785 | (license license:artistic2.0))) | |
786 | ||
f8a5af46 RW |
787 | (define-public r-do-db |
788 | (package | |
789 | (name "r-do-db") | |
790 | (version "2.9") | |
791 | (source (origin | |
792 | (method url-fetch) | |
793 | ;; We cannot use bioconductor-uri here because this tarball is | |
794 | ;; located under "data/annotation/" instead of "bioc/". | |
795 | (uri (string-append "https://www.bioconductor.org/packages/" | |
796 | "release/data/annotation/src/contrib/" | |
797 | "DO.db_" version ".tar.gz")) | |
798 | (sha256 | |
799 | (base32 | |
800 | "10bqqa124l61ivzy4mdd3z3ar9a6537qbxw23pc4y9w8a6dwnavn")))) | |
801 | (properties | |
802 | `((upstream-name . "DO.db"))) | |
803 | (build-system r-build-system) | |
804 | (propagated-inputs | |
805 | `(("r-annotationdbi" ,r-annotationdbi))) | |
806 | (home-page "https://www.bioconductor.org/packages/DO.db/") | |
807 | (synopsis "Annotation maps describing the entire Disease Ontology") | |
808 | (description | |
809 | "This package provides a set of annotation maps describing the entire | |
810 | Disease Ontology.") | |
811 | (license license:artistic2.0))) | |
812 | ||
83b42091 RW |
813 | (define-public r-pfam-db |
814 | (package | |
815 | (name "r-pfam-db") | |
816 | (version "3.8.2") | |
817 | (source | |
818 | (origin | |
819 | (method url-fetch) | |
820 | (uri (bioconductor-uri "PFAM.db" version 'annotation)) | |
821 | (sha256 | |
822 | (base32 | |
823 | "0rn1arzzcniy3yyc4yc44vn40g0cqss37dhwnvsgxpfayqq1k59s")))) | |
824 | (properties `((upstream-name . "PFAM.db"))) | |
825 | (build-system r-build-system) | |
826 | (propagated-inputs | |
827 | `(("r-annotationdbi" ,r-annotationdbi))) | |
828 | (home-page "https://bioconductor.org/packages/PFAM.db") | |
829 | (synopsis "Set of protein ID mappings for PFAM") | |
830 | (description | |
831 | "This package provides a set of protein ID mappings for PFAM, assembled | |
832 | using data from public repositories.") | |
833 | (license license:artistic2.0))) | |
834 | ||
2cc51108 | 835 | \f |
557a1089 RW |
836 | ;;; Experiment data |
837 | ||
692bce15 RW |
838 | (define-public r-abadata |
839 | (package | |
840 | (name "r-abadata") | |
841 | (version "1.12.0") | |
842 | (source (origin | |
843 | (method url-fetch) | |
844 | ;; We cannot use bioconductor-uri here because this tarball is | |
845 | ;; located under "data/experiment/" instead of "bioc/". | |
846 | (uri (string-append "https://www.bioconductor.org/packages/" | |
847 | "release/data/experiment/src/contrib/" | |
848 | "ABAData_" version ".tar.gz")) | |
849 | (sha256 | |
850 | (base32 | |
851 | "1bmj341xcymlrk02gss5vvrqc4ddas0rdw39lnpsj98hq6n11p5z")))) | |
852 | (properties | |
853 | `((upstream-name . "ABAData"))) | |
854 | (build-system r-build-system) | |
855 | (propagated-inputs | |
856 | `(("r-annotationdbi" ,r-annotationdbi))) | |
857 | (home-page "https://www.bioconductor.org/packages/ABAData/") | |
858 | (synopsis "Gene expression in human brain regions from Allen Brain Atlas") | |
859 | (description | |
860 | "This package provides the data for the gene expression enrichment | |
861 | analysis conducted in the package ABAEnrichment. The package includes three | |
862 | datasets which are derived from the Allen Brain Atlas: | |
863 | ||
864 | @enumerate | |
865 | @item Gene expression data from Human Brain (adults) averaged across donors, | |
866 | @item Gene expression data from the Developing Human Brain pooled into five | |
867 | age categories and averaged across donors, and | |
868 | @item a developmental effect score based on the Developing Human Brain | |
869 | expression data. | |
870 | @end enumerate | |
871 | ||
872 | All datasets are restricted to protein coding genes.") | |
873 | (license license:gpl2+))) | |
874 | ||
b50c9660 RW |
875 | (define-public r-arrmdata |
876 | (package | |
877 | (name "r-arrmdata") | |
878 | (version "1.18.0") | |
879 | (source (origin | |
880 | (method url-fetch) | |
881 | ;; We cannot use bioconductor-uri here because this tarball is | |
882 | ;; located under "data/experiment/" instead of "bioc/". | |
883 | (uri (string-append "https://www.bioconductor.org/packages/" | |
884 | "release/data/experiment/src/contrib/" | |
885 | "ARRmData_" version ".tar.gz")) | |
886 | (sha256 | |
887 | (base32 | |
888 | "0r1y3zn7ly4k3ngx55vfavn9s6aidbddlv2fbmj7hj3hvpslmyly")))) | |
889 | (properties | |
890 | `((upstream-name . "ARRmData"))) | |
891 | (build-system r-build-system) | |
892 | (home-page "https://www.bioconductor.org/packages/ARRmData/") | |
893 | (synopsis "Example dataset for normalization of Illumina 450k methylation data") | |
894 | (description | |
895 | "This package provides raw beta values from 36 samples across 3 groups | |
896 | from Illumina 450k methylation arrays.") | |
897 | (license license:artistic2.0))) | |
898 | ||
557a1089 RW |
899 | (define-public r-hsmmsinglecell |
900 | (package | |
901 | (name "r-hsmmsinglecell") | |
902 | (version "1.2.0") | |
903 | (source (origin | |
904 | (method url-fetch) | |
905 | ;; We cannot use bioconductor-uri here because this tarball is | |
906 | ;; located under "data/experiment/" instead of "bioc/". | |
907 | (uri (string-append "https://www.bioconductor.org/packages/" | |
908 | "release/data/experiment/src/contrib/" | |
909 | "HSMMSingleCell_" version ".tar.gz")) | |
910 | (sha256 | |
911 | (base32 | |
912 | "1vxnr8gr6md85g39csy7g2sqqajiqgyvznys2qa9yixd2b01yph9")))) | |
913 | (properties | |
914 | `((upstream-name . "HSMMSingleCell"))) | |
915 | (build-system r-build-system) | |
916 | (home-page "https://www.bioconductor.org/packages/HSMMSingleCell/") | |
917 | (synopsis "Single-cell RNA-Seq for differentiating human skeletal muscle myoblasts (HSMM)") | |
918 | (description | |
919 | "Skeletal myoblasts undergo a well-characterized sequence of | |
920 | morphological and transcriptional changes during differentiation. In this | |
921 | experiment, primary @dfn{human skeletal muscle myoblasts} (HSMM) were expanded | |
922 | under high mitogen conditions (GM) and then differentiated by switching to | |
923 | low-mitogen media (DM). RNA-Seq libraries were sequenced from each of several | |
924 | hundred cells taken over a time-course of serum-induced differentiation. | |
925 | Between 49 and 77 cells were captured at each of four time points (0, 24, 48, | |
926 | 72 hours) following serum switch using the Fluidigm C1 microfluidic system. | |
927 | RNA from each cell was isolated and used to construct mRNA-Seq libraries, | |
928 | which were then sequenced to a depth of ~4 million reads per library, | |
929 | resulting in a complete gene expression profile for each cell.") | |
930 | (license license:artistic2.0))) | |
ad8f46c6 | 931 | |
932 | (define-public r-all | |
933 | (package | |
934 | (name "r-all") | |
935 | (version "1.26.0") | |
936 | (source (origin | |
937 | (method url-fetch) | |
938 | ;; We cannot use bioconductor-uri here because this tarball is | |
939 | ;; located under "data/experiment/" instead of "bioc/". | |
940 | (uri (string-append "https://www.bioconductor.org/packages/" | |
941 | "release/data/experiment/src/contrib/" | |
942 | "ALL_" version ".tar.gz")) | |
943 | (sha256 | |
944 | (base32 | |
945 | "1z7kpjw4ndj6fkxwvhqf3gawhrn26ksrlns7j2c78qzxqmjndik9")))) | |
946 | (properties `((upstream-name . "ALL"))) | |
947 | (build-system r-build-system) | |
948 | (propagated-inputs | |
949 | `(("r-biobase" ,r-biobase))) | |
950 | (home-page "https://bioconductor.org/packages/ALL") | |
951 | (synopsis "Acute Lymphoblastic Leukemia data from the Ritz laboratory") | |
952 | (description | |
953 | "The data consist of microarrays from 128 different individuals with | |
954 | @dfn{acute lymphoblastic leukemia} (ALL). A number of additional covariates | |
955 | are available. The data have been normalized (using rma) and it is the | |
956 | jointly normalized data that are available here. The data are presented in | |
957 | the form of an @code{exprSet} object.") | |
958 | (license license:artistic2.0))) | |
557a1089 | 959 | |
53b1e10f RW |
960 | (define-public r-affydata |
961 | (package | |
962 | (name "r-affydata") | |
963 | (version "1.32.0") | |
964 | (source | |
965 | (origin | |
966 | (method url-fetch) | |
967 | (uri (bioconductor-uri "affydata" version 'experiment)) | |
968 | (sha256 | |
969 | (base32 | |
970 | "1l9qhmjqgbrdl9cmd74rlnvmvr6mslbmckb83n0211whp2i0b7h5")))) | |
971 | (properties `((upstream-name . "affydata"))) | |
972 | (build-system r-build-system) | |
973 | (propagated-inputs | |
974 | `(("r-affy" ,r-affy))) | |
975 | (home-page "https://bioconductor.org/packages/affydata/") | |
976 | (synopsis "Affymetrix data for demonstration purposes") | |
977 | (description | |
978 | "This package provides example datasets that represent 'real world | |
979 | examples' of Affymetrix data, unlike the artificial examples included in the | |
980 | package @code{affy}.") | |
981 | (license license:gpl2+))) | |
982 | ||
557a1089 RW |
983 | \f |
984 | ;;; Packages | |
985 | ||
14bba460 RW |
986 | (define-public r-biocgenerics |
987 | (package | |
988 | (name "r-biocgenerics") | |
81a1c45d | 989 | (version "0.30.0") |
14bba460 RW |
990 | (source (origin |
991 | (method url-fetch) | |
992 | (uri (bioconductor-uri "BiocGenerics" version)) | |
993 | (sha256 | |
994 | (base32 | |
81a1c45d | 995 | "1n87686bg5nmpqdpzwv1h551dkbxp9wk6wbmzpkgm71qxnk2yv9f")))) |
14bba460 RW |
996 | (properties |
997 | `((upstream-name . "BiocGenerics"))) | |
998 | (build-system r-build-system) | |
999 | (home-page "https://bioconductor.org/packages/BiocGenerics") | |
1000 | (synopsis "S4 generic functions for Bioconductor") | |
1001 | (description | |
1002 | "This package provides S4 generic functions needed by many Bioconductor | |
1003 | packages.") | |
1004 | (license license:artistic2.0))) | |
1005 | ||
5cf940de RW |
1006 | (define-public r-affycomp |
1007 | (package | |
1008 | (name "r-affycomp") | |
1009 | (version "1.60.0") | |
1010 | (source | |
1011 | (origin | |
1012 | (method url-fetch) | |
1013 | (uri (bioconductor-uri "affycomp" version)) | |
1014 | (sha256 | |
1015 | (base32 | |
1016 | "1nijqljg5r3qj1y6an0i58sby76hqacj3a3nvainxic4n5wlzh0n")))) | |
1017 | (properties `((upstream-name . "affycomp"))) | |
1018 | (build-system r-build-system) | |
1019 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
1020 | (home-page "https://bioconductor.org/packages/affycomp/") | |
1021 | (synopsis "Graphics toolbox for assessment of Affymetrix expression measures") | |
1022 | (description | |
1023 | "The package contains functions that can be used to compare expression | |
1024 | measures for Affymetrix Oligonucleotide Arrays.") | |
1025 | (license license:gpl2+))) | |
1026 | ||
5094aa94 RW |
1027 | (define-public r-affycompatible |
1028 | (package | |
1029 | (name "r-affycompatible") | |
1030 | (version "1.44.0") | |
1031 | (source | |
1032 | (origin | |
1033 | (method url-fetch) | |
1034 | (uri (bioconductor-uri "AffyCompatible" version)) | |
1035 | (sha256 | |
1036 | (base32 | |
1037 | "1zi96qa6vkgwvvy5cn6c3p1kbfsaz74zsw2kjxarz5qs744f0xvs")))) | |
1038 | (properties | |
1039 | `((upstream-name . "AffyCompatible"))) | |
1040 | (build-system r-build-system) | |
1041 | (propagated-inputs | |
1042 | `(("r-biostrings" ,r-biostrings) | |
1043 | ("r-rcurl" ,r-rcurl) | |
1044 | ("r-xml" ,r-xml))) | |
1045 | (home-page "https://bioconductor.org/packages/AffyCompatible/") | |
1046 | (synopsis "Work with Affymetrix GeneChip files") | |
1047 | (description | |
1048 | "This package provides an interface to Affymetrix chip annotation and | |
1049 | sample attribute files. The package allows an easy way for users to download | |
1050 | and manage local data bases of Affynmetrix NetAffx annotation files. It also | |
1051 | provides access to @dfn{GeneChip Operating System} (GCOS) and @dfn{GeneChip | |
1052 | Command Console} (AGCC)-compatible sample annotation files.") | |
1053 | (license license:artistic2.0))) | |
1054 | ||
4ca2d6c1 RW |
1055 | (define-public r-affycontam |
1056 | (package | |
1057 | (name "r-affycontam") | |
1058 | (version "1.42.0") | |
1059 | (source | |
1060 | (origin | |
1061 | (method url-fetch) | |
1062 | (uri (bioconductor-uri "affyContam" version)) | |
1063 | (sha256 | |
1064 | (base32 | |
1065 | "0nzk1cm26rhmym753wyhn35hqnz5lvavi3i5qfgdvhxgjy3m1jgp")))) | |
1066 | (properties `((upstream-name . "affyContam"))) | |
1067 | (build-system r-build-system) | |
1068 | (propagated-inputs | |
1069 | `(("r-affy" ,r-affy) | |
1070 | ("r-affydata" ,r-affydata) | |
1071 | ("r-biobase" ,r-biobase))) | |
1072 | (home-page "https://bioconductor.org/packages/affyContam/") | |
1073 | (synopsis "Structured corruption of Affymetrix CEL file data") | |
1074 | (description | |
1075 | "Microarray quality assessment is a major concern of microarray analysts. | |
1076 | This package provides some simple approaches to in silico creation of quality | |
1077 | problems in CEL-level data to help evaluate performance of quality metrics.") | |
1078 | (license license:artistic2.0))) | |
1079 | ||
7097c700 RW |
1080 | (define-public r-annotate |
1081 | (package | |
1082 | (name "r-annotate") | |
0c53332a | 1083 | (version "1.62.0") |
7097c700 RW |
1084 | (source |
1085 | (origin | |
1086 | (method url-fetch) | |
1087 | (uri (bioconductor-uri "annotate" version)) | |
1088 | (sha256 | |
1089 | (base32 | |
0c53332a | 1090 | "0hww0h4b7bv37mnjviazy247mnzj72z5linwm1gvljrgqv3bagcs")))) |
7097c700 RW |
1091 | (build-system r-build-system) |
1092 | (propagated-inputs | |
1093 | `(("r-annotationdbi" ,r-annotationdbi) | |
1094 | ("r-biobase" ,r-biobase) | |
1095 | ("r-biocgenerics" ,r-biocgenerics) | |
1096 | ("r-dbi" ,r-dbi) | |
1097 | ("r-rcurl" ,r-rcurl) | |
1098 | ("r-xml" ,r-xml) | |
1099 | ("r-xtable" ,r-xtable))) | |
1100 | (home-page | |
1101 | "https://bioconductor.org/packages/annotate") | |
1102 | (synopsis "Annotation for microarrays") | |
1103 | (description "This package provides R environments for the annotation of | |
1104 | microarrays.") | |
1105 | (license license:artistic2.0))) | |
1106 | ||
fa596599 RW |
1107 | (define-public r-hpar |
1108 | (package | |
1109 | (name "r-hpar") | |
43a23a07 | 1110 | (version "1.26.0") |
fa596599 RW |
1111 | (source |
1112 | (origin | |
1113 | (method url-fetch) | |
1114 | (uri (bioconductor-uri "hpar" version)) | |
1115 | (sha256 | |
1116 | (base32 | |
43a23a07 | 1117 | "1mnld60nrn6qpb24sz2sy8vlw3wkhfc3z726gi67l8b5mdmkxgg5")))) |
fa596599 RW |
1118 | (build-system r-build-system) |
1119 | (home-page "https://bioconductor.org/packages/hpar/") | |
1120 | (synopsis "Human Protein Atlas in R") | |
1121 | (description "This package provides a simple interface to and data from | |
1122 | the Human Protein Atlas project.") | |
1123 | (license license:artistic2.0))) | |
183ce988 RJ |
1124 | |
1125 | (define-public r-regioner | |
1126 | (package | |
1127 | (name "r-regioner") | |
ec0270b1 | 1128 | (version "1.16.4") |
183ce988 RJ |
1129 | (source |
1130 | (origin | |
1131 | (method url-fetch) | |
1132 | (uri (bioconductor-uri "regioneR" version)) | |
1133 | (sha256 | |
1134 | (base32 | |
ec0270b1 | 1135 | "0xzk057h6nkr3rvd412prxgnkpq625b90laj1kwb0i5q8j5ch760")))) |
183ce988 RJ |
1136 | (properties `((upstream-name . "regioneR"))) |
1137 | (build-system r-build-system) | |
1138 | (propagated-inputs | |
d639d888 | 1139 | `(("r-biostrings" ,r-biostrings) |
183ce988 | 1140 | ("r-bsgenome" ,r-bsgenome) |
183ce988 | 1141 | ("r-genomeinfodb" ,r-genomeinfodb) |
d639d888 | 1142 | ("r-genomicranges" ,r-genomicranges) |
72427c72 | 1143 | ("r-iranges" ,r-iranges) |
d639d888 RW |
1144 | ("r-memoise" ,r-memoise) |
1145 | ("r-rtracklayer" ,r-rtracklayer) | |
72427c72 | 1146 | ("r-s4vectors" ,r-s4vectors))) |
183ce988 RJ |
1147 | (home-page "https://bioconductor.org/packages/regioneR/") |
1148 | (synopsis "Association analysis of genomic regions") | |
1149 | (description "This package offers a statistical framework based on | |
1150 | customizable permutation tests to assess the association between genomic | |
1151 | region sets and other genomic features.") | |
1152 | (license license:artistic2.0))) | |
a5b56a53 | 1153 | |
15184fb3 RW |
1154 | (define-public r-reportingtools |
1155 | (package | |
1156 | (name "r-reportingtools") | |
1157 | (version "2.24.0") | |
1158 | (source | |
1159 | (origin | |
1160 | (method url-fetch) | |
1161 | (uri (bioconductor-uri "ReportingTools" version)) | |
1162 | (sha256 | |
1163 | (base32 | |
1164 | "16ska7mlacka0xi8x2icy8v42vaxccb3a1x73szmfvcrwr592qsc")))) | |
1165 | (properties | |
1166 | `((upstream-name . "ReportingTools"))) | |
1167 | (build-system r-build-system) | |
1168 | (propagated-inputs | |
1169 | `(("r-annotate" ,r-annotate) | |
1170 | ("r-annotationdbi" ,r-annotationdbi) | |
1171 | ("r-biobase" ,r-biobase) | |
1172 | ("r-biocgenerics" ,r-biocgenerics) | |
1173 | ("r-category" ,r-category) | |
1174 | ("r-deseq2" ,r-deseq2) | |
1175 | ("r-edger" ,r-edger) | |
1176 | ("r-ggbio" ,r-ggbio) | |
1177 | ("r-ggplot2" ,r-ggplot2) | |
1178 | ("r-gostats" ,r-gostats) | |
1179 | ("r-gseabase" ,r-gseabase) | |
1180 | ("r-hwriter" ,r-hwriter) | |
1181 | ("r-iranges" ,r-iranges) | |
1182 | ("r-knitr" ,r-knitr) | |
1183 | ("r-lattice" ,r-lattice) | |
1184 | ("r-limma" ,r-limma) | |
1185 | ("r-pfam-db" ,r-pfam-db) | |
1186 | ("r-r-utils" ,r-r-utils) | |
1187 | ("r-xml" ,r-xml))) | |
1188 | (home-page "https://bioconductor.org/packages/ReportingTools/") | |
1189 | (synopsis "Tools for making reports in various formats") | |
1190 | (description | |
1191 | "The ReportingTools package enables users to easily display reports of | |
1192 | analysis results generated from sources such as microarray and sequencing | |
1193 | data. The package allows users to create HTML pages that may be viewed on a | |
1194 | web browser, or in other formats. Users can generate tables with sortable and | |
1195 | filterable columns, make and display plots, and link table entries to other | |
1196 | data sources such as NCBI or larger plots within the HTML page. Using the | |
1197 | package, users can also produce a table of contents page to link various | |
1198 | reports together for a particular project that can be viewed in a web | |
1199 | browser.") | |
1200 | (license license:artistic2.0))) | |
1201 | ||
bfb93b48 RW |
1202 | (define-public r-geneplotter |
1203 | (package | |
1204 | (name "r-geneplotter") | |
3e1bc88c | 1205 | (version "1.62.0") |
bfb93b48 RW |
1206 | (source |
1207 | (origin | |
1208 | (method url-fetch) | |
1209 | (uri (bioconductor-uri "geneplotter" version)) | |
1210 | (sha256 | |
1211 | (base32 | |
3e1bc88c | 1212 | "0jlqs20mqr0wgmjgzkzaynp3cy1z3xjzpz7055c1qi42fhimmimb")))) |
bfb93b48 RW |
1213 | (build-system r-build-system) |
1214 | (propagated-inputs | |
1215 | `(("r-annotate" ,r-annotate) | |
1216 | ("r-annotationdbi" ,r-annotationdbi) | |
1217 | ("r-biobase" ,r-biobase) | |
1218 | ("r-biocgenerics" ,r-biocgenerics) | |
1219 | ("r-lattice" ,r-lattice) | |
1220 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
1221 | (home-page "https://bioconductor.org/packages/geneplotter") | |
1222 | (synopsis "Graphics functions for genomic data") | |
1223 | (description | |
1224 | "This package provides functions for plotting genomic data.") | |
1225 | (license license:artistic2.0))) | |
1226 | ||
4dc2ecc2 RW |
1227 | (define-public r-qvalue |
1228 | (package | |
1229 | (name "r-qvalue") | |
e02162f7 | 1230 | (version "2.16.0") |
4dc2ecc2 RW |
1231 | (source |
1232 | (origin | |
1233 | (method url-fetch) | |
1234 | (uri (bioconductor-uri "qvalue" version)) | |
1235 | (sha256 | |
1236 | (base32 | |
e02162f7 | 1237 | "00mahhwb4n2s6nycwkdkjs2qgyyyi7hyrby3qr269krprr6q3lh5")))) |
4dc2ecc2 RW |
1238 | (build-system r-build-system) |
1239 | (propagated-inputs | |
1240 | `(("r-ggplot2" ,r-ggplot2) | |
1241 | ("r-reshape2" ,r-reshape2))) | |
1242 | (home-page "http://github.com/jdstorey/qvalue") | |
1243 | (synopsis "Q-value estimation for false discovery rate control") | |
1244 | (description | |
1245 | "This package takes a list of p-values resulting from the simultaneous | |
1246 | testing of many hypotheses and estimates their q-values and local @dfn{false | |
1247 | discovery rate} (FDR) values. The q-value of a test measures the proportion | |
1248 | of false positives incurred when that particular test is called significant. | |
1249 | The local FDR measures the posterior probability the null hypothesis is true | |
1250 | given the test's p-value. Various plots are automatically generated, allowing | |
1251 | one to make sensible significance cut-offs. The software can be applied to | |
1252 | problems in genomics, brain imaging, astrophysics, and data mining.") | |
1253 | ;; Any version of the LGPL. | |
1254 | (license license:lgpl3+))) | |
1255 | ||
a5b56a53 RJ |
1256 | (define-public r-diffbind |
1257 | (package | |
1258 | (name "r-diffbind") | |
4c221b3b | 1259 | (version "2.12.0") |
a5b56a53 RJ |
1260 | (source |
1261 | (origin | |
1262 | (method url-fetch) | |
1263 | (uri (bioconductor-uri "DiffBind" version)) | |
1264 | (sha256 | |
1265 | (base32 | |
4c221b3b | 1266 | "1ialb1j2xa21a8dzss76qky83rg8y6jwdwi0mhy8b088zvxavich")))) |
a5b56a53 RJ |
1267 | (properties `((upstream-name . "DiffBind"))) |
1268 | (build-system r-build-system) | |
1269 | (inputs | |
1270 | `(("zlib" ,zlib))) | |
1271 | (propagated-inputs | |
1272 | `(("r-amap" ,r-amap) | |
1273 | ("r-biocparallel" ,r-biocparallel) | |
1274 | ("r-deseq2" ,r-deseq2) | |
1275 | ("r-dplyr" ,r-dplyr) | |
1276 | ("r-edger" ,r-edger) | |
1277 | ("r-genomicalignments" ,r-genomicalignments) | |
45bbccf4 RW |
1278 | ("r-genomicranges" ,r-genomicranges) |
1279 | ("r-ggplot2" ,r-ggplot2) | |
a5b56a53 RJ |
1280 | ("r-ggrepel" ,r-ggrepel) |
1281 | ("r-gplots" ,r-gplots) | |
1282 | ("r-iranges" ,r-iranges) | |
1283 | ("r-lattice" ,r-lattice) | |
1284 | ("r-limma" ,r-limma) | |
1285 | ("r-locfit" ,r-locfit) | |
1286 | ("r-rcolorbrewer" , r-rcolorbrewer) | |
1287 | ("r-rcpp" ,r-rcpp) | |
4c221b3b | 1288 | ("r-rhtslib" ,r-rhtslib) |
a5b56a53 RJ |
1289 | ("r-rsamtools" ,r-rsamtools) |
1290 | ("r-s4vectors" ,r-s4vectors) | |
45bbccf4 | 1291 | ("r-summarizedexperiment" ,r-summarizedexperiment) |
4c221b3b | 1292 | ("r-systempiper" ,r-systempiper))) |
a5b56a53 RJ |
1293 | (home-page "http://bioconductor.org/packages/DiffBind") |
1294 | (synopsis "Differential binding analysis of ChIP-Seq peak data") | |
1295 | (description | |
1296 | "This package computes differentially bound sites from multiple | |
1297 | ChIP-seq experiments using affinity (quantitative) data. Also enables | |
1298 | occupancy (overlap) analysis and plotting functions.") | |
1299 | (license license:artistic2.0))) | |
6d94bf6b RJ |
1300 | |
1301 | (define-public r-ripseeker | |
1302 | (package | |
1303 | (name "r-ripseeker") | |
0968a448 | 1304 | (version "1.24.0") |
6d94bf6b RJ |
1305 | (source |
1306 | (origin | |
1307 | (method url-fetch) | |
1308 | (uri (bioconductor-uri "RIPSeeker" version)) | |
1309 | (sha256 | |
1310 | (base32 | |
0968a448 | 1311 | "0rfff4wal51iji0m74mgnrlcq6i41nq5b79mv5brv7mab3g0cv43")))) |
6d94bf6b RJ |
1312 | (properties `((upstream-name . "RIPSeeker"))) |
1313 | (build-system r-build-system) | |
1314 | (propagated-inputs | |
1315 | `(("r-s4vectors" ,r-s4vectors) | |
1316 | ("r-iranges" ,r-iranges) | |
1317 | ("r-genomicranges" ,r-genomicranges) | |
1318 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
1319 | ("r-rsamtools" ,r-rsamtools) | |
1320 | ("r-genomicalignments" ,r-genomicalignments) | |
1321 | ("r-rtracklayer" ,r-rtracklayer))) | |
1322 | (home-page "http://bioconductor.org/packages/RIPSeeker") | |
1323 | (synopsis | |
1324 | "Identifying protein-associated transcripts from RIP-seq experiments") | |
1325 | (description | |
1326 | "This package infers and discriminates RIP peaks from RIP-seq alignments | |
1327 | using two-state HMM with negative binomial emission probability. While | |
1328 | RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides | |
1329 | a suite of bioinformatics tools integrated within this self-contained software | |
1330 | package comprehensively addressing issues ranging from post-alignments | |
1331 | processing to visualization and annotation.") | |
1332 | (license license:gpl2))) | |
a6ae9ffd RJ |
1333 | |
1334 | (define-public r-multtest | |
1335 | (package | |
1336 | (name "r-multtest") | |
588b63c2 | 1337 | (version "2.40.0") |
a6ae9ffd RJ |
1338 | (source |
1339 | (origin | |
1340 | (method url-fetch) | |
1341 | (uri (bioconductor-uri "multtest" version)) | |
1342 | (sha256 | |
1343 | (base32 | |
588b63c2 | 1344 | "0vy9wk1111qm69xy4r4n01b9rw60dsrcj2169jd45yiq63cdq7bv")))) |
a6ae9ffd RJ |
1345 | (build-system r-build-system) |
1346 | (propagated-inputs | |
1347 | `(("r-survival" ,r-survival) | |
1348 | ("r-biocgenerics" ,r-biocgenerics) | |
1349 | ("r-biobase" ,r-biobase) | |
1350 | ("r-mass" ,r-mass))) | |
1351 | (home-page "http://bioconductor.org/packages/multtest") | |
1352 | (synopsis "Resampling-based multiple hypothesis testing") | |
1353 | (description | |
1354 | "This package can do non-parametric bootstrap and permutation | |
1355 | resampling-based multiple testing procedures (including empirical Bayes | |
1356 | methods) for controlling the family-wise error rate (FWER), generalized | |
1357 | family-wise error rate (gFWER), tail probability of the proportion of | |
1358 | false positives (TPPFP), and false discovery rate (FDR). Several choices | |
1359 | of bootstrap-based null distribution are implemented (centered, centered | |
1360 | and scaled, quantile-transformed). Single-step and step-wise methods are | |
1361 | available. Tests based on a variety of T- and F-statistics (including | |
1362 | T-statistics based on regression parameters from linear and survival models | |
1363 | as well as those based on correlation parameters) are included. When probing | |
1364 | hypotheses with T-statistics, users may also select a potentially faster null | |
1365 | distribution which is multivariate normal with mean zero and variance | |
1366 | covariance matrix derived from the vector influence function. Results are | |
1367 | reported in terms of adjusted P-values, confidence regions and test statistic | |
1368 | cutoffs. The procedures are directly applicable to identifying differentially | |
1369 | expressed genes in DNA microarray experiments.") | |
1370 | (license license:lgpl3))) | |
793f83ef | 1371 | |
5dfe4912 RW |
1372 | (define-public r-graph |
1373 | (package | |
1374 | (name "r-graph") | |
a61bcb28 | 1375 | (version "1.62.0") |
5dfe4912 RW |
1376 | (source (origin |
1377 | (method url-fetch) | |
1378 | (uri (bioconductor-uri "graph" version)) | |
1379 | (sha256 | |
1380 | (base32 | |
a61bcb28 | 1381 | "0rs81a8kp7nfzsfy2d11mlrjf4z156075p52wvz9nvi3vc6l348w")))) |
5dfe4912 RW |
1382 | (build-system r-build-system) |
1383 | (propagated-inputs | |
1384 | `(("r-biocgenerics" ,r-biocgenerics))) | |
1385 | (home-page "https://bioconductor.org/packages/graph") | |
1386 | (synopsis "Handle graph data structures in R") | |
1387 | (description | |
1388 | "This package implements some simple graph handling capabilities for R.") | |
1389 | (license license:artistic2.0))) | |
1390 | ||
a207bca2 RW |
1391 | (define-public r-codedepends |
1392 | (package | |
1393 | (name "r-codedepends") | |
1394 | (version "0.6.5") | |
1395 | (source | |
1396 | (origin | |
1397 | (method url-fetch) | |
1398 | (uri (cran-uri "CodeDepends" version)) | |
1399 | (sha256 | |
1400 | (base32 | |
1401 | "0l7kiv3awx50glf5cs841b4zzsff1ml90f0zr868ygvwsr4ps1hq")))) | |
1402 | (properties `((upstream-name . "CodeDepends"))) | |
1403 | (build-system r-build-system) | |
1404 | (propagated-inputs | |
1405 | `(("r-codetools" ,r-codetools) | |
1406 | ("r-graph" ,r-graph) | |
1407 | ("r-xml" ,r-xml))) | |
1408 | (home-page "http://cran.r-project.org/web/packages/CodeDepends") | |
1409 | (synopsis "Analysis of R code for reproducible research and code comprehension") | |
1410 | (description | |
1411 | "This package provides tools for analyzing R expressions or blocks of | |
1412 | code and determining the dependencies between them. It focuses on R scripts, | |
1413 | but can be used on the bodies of functions. There are many facilities | |
1414 | including the ability to summarize or get a high-level view of code, | |
1415 | determining dependencies between variables, code improvement suggestions.") | |
1416 | ;; Any version of the GPL | |
1417 | (license (list license:gpl2+ license:gpl3+)))) | |
1418 | ||
793f83ef RJ |
1419 | (define-public r-chippeakanno |
1420 | (package | |
1421 | (name "r-chippeakanno") | |
109b8ad5 | 1422 | (version "3.18.2") |
793f83ef RJ |
1423 | (source |
1424 | (origin | |
1425 | (method url-fetch) | |
1426 | (uri (bioconductor-uri "ChIPpeakAnno" version)) | |
1427 | (sha256 | |
1428 | (base32 | |
109b8ad5 | 1429 | "0wzwdxvvr7wknz5jnan0wsp81c1gv4d2qx0mrb1yybqf4z068779")))) |
793f83ef RJ |
1430 | (properties `((upstream-name . "ChIPpeakAnno"))) |
1431 | (build-system r-build-system) | |
1432 | (propagated-inputs | |
85c1d20f RW |
1433 | `(("r-annotationdbi" ,r-annotationdbi) |
1434 | ("r-biobase" ,r-biobase) | |
1435 | ("r-biocgenerics" ,r-biocgenerics) | |
57d2fcd9 | 1436 | ("r-biocmanager" ,r-biocmanager) |
793f83ef | 1437 | ("r-biomart" ,r-biomart) |
85c1d20f | 1438 | ("r-biostrings" ,r-biostrings) |
793f83ef | 1439 | ("r-bsgenome" ,r-bsgenome) |
85c1d20f RW |
1440 | ("r-dbi" ,r-dbi) |
1441 | ("r-delayedarray" ,r-delayedarray) | |
1442 | ("r-ensembldb" ,r-ensembldb) | |
1443 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1444 | ("r-genomicalignments" ,r-genomicalignments) | |
793f83ef | 1445 | ("r-genomicfeatures" ,r-genomicfeatures) |
f794e85d | 1446 | ("r-genomicranges" ,r-genomicranges) |
85c1d20f RW |
1447 | ("r-go-db" ,r-go-db) |
1448 | ("r-graph" ,r-graph) | |
1449 | ("r-idr" ,r-idr) | |
f794e85d | 1450 | ("r-iranges" ,r-iranges) |
793f83ef | 1451 | ("r-limma" ,r-limma) |
85c1d20f | 1452 | ("r-matrixstats" ,r-matrixstats) |
793f83ef RJ |
1453 | ("r-multtest" ,r-multtest) |
1454 | ("r-rbgl" ,r-rbgl) | |
793f83ef | 1455 | ("r-regioner" ,r-regioner) |
85c1d20f RW |
1456 | ("r-rsamtools" ,r-rsamtools) |
1457 | ("r-rtracklayer" ,r-rtracklayer) | |
f794e85d | 1458 | ("r-s4vectors" ,r-s4vectors) |
793f83ef | 1459 | ("r-seqinr" ,r-seqinr) |
793f83ef | 1460 | ("r-summarizedexperiment" ,r-summarizedexperiment) |
793f83ef RJ |
1461 | ("r-venndiagram" ,r-venndiagram))) |
1462 | (home-page "http://bioconductor.org/packages/ChIPpeakAnno") | |
1463 | (synopsis "Peaks annotation from ChIP-seq and ChIP-chip experiments") | |
1464 | (description | |
1465 | "The package includes functions to retrieve the sequences around the peak, | |
1466 | obtain enriched Gene Ontology (GO) terms, find the nearest gene, exon, miRNA or | |
1467 | custom features such as most conserved elements and other transcription factor | |
1468 | binding sites supplied by users. Starting 2.0.5, new functions have been added | |
1469 | for finding the peaks with bi-directional promoters with summary statistics | |
1470 | (peaksNearBDP), for summarizing the occurrence of motifs in peaks | |
1471 | (summarizePatternInPeaks) and for adding other IDs to annotated peaks or | |
1472 | enrichedGO (addGeneIDs).") | |
1473 | (license license:gpl2+))) | |
164502d8 RJ |
1474 | |
1475 | (define-public r-marray | |
1476 | (package | |
1477 | (name "r-marray") | |
bcb95b7a | 1478 | (version "1.62.0") |
164502d8 RJ |
1479 | (source (origin |
1480 | (method url-fetch) | |
1481 | (uri (bioconductor-uri "marray" version)) | |
1482 | (sha256 | |
bcb95b7a | 1483 | (base32 "000745d7gxka8cx4jwxf0p128jk90dw6wi3y8dkrkyz2arkl29yz")))) |
164502d8 RJ |
1484 | (build-system r-build-system) |
1485 | (propagated-inputs | |
67487088 | 1486 | `(("r-limma" ,r-limma))) |
164502d8 RJ |
1487 | (home-page "http://bioconductor.org/packages/marray") |
1488 | (synopsis "Exploratory analysis for two-color spotted microarray data") | |
1489 | (description "This package contains class definitions for two-color spotted | |
ab8979fc | 1490 | microarray data. It also includes functions for data input, diagnostic plots, |
164502d8 RJ |
1491 | normalization and quality checking.") |
1492 | (license license:lgpl2.0+))) | |
0416a0d4 RJ |
1493 | |
1494 | (define-public r-cghbase | |
1495 | (package | |
1496 | (name "r-cghbase") | |
8efb842f | 1497 | (version "1.44.0") |
0416a0d4 RJ |
1498 | (source (origin |
1499 | (method url-fetch) | |
1500 | (uri (bioconductor-uri "CGHbase" version)) | |
1501 | (sha256 | |
8efb842f | 1502 | (base32 "0z9lvn5dxym6kc8ak5fsqkipv2p4z49va3cyz1ch8rw477k2iwvm")))) |
0416a0d4 RJ |
1503 | (properties `((upstream-name . "CGHbase"))) |
1504 | (build-system r-build-system) | |
1505 | (propagated-inputs | |
1506 | `(("r-biobase" ,r-biobase) | |
1507 | ("r-marray" ,r-marray))) | |
1508 | (home-page "http://bioconductor.org/packages/CGHbase") | |
1509 | (synopsis "Base functions and classes for arrayCGH data analysis") | |
1510 | (description "This package contains functions and classes that are needed by | |
1511 | the @code{arrayCGH} packages.") | |
1512 | (license license:gpl2+))) | |
67ee83d6 RJ |
1513 | |
1514 | (define-public r-cghcall | |
1515 | (package | |
1516 | (name "r-cghcall") | |
23177309 | 1517 | (version "2.46.0") |
67ee83d6 RJ |
1518 | (source (origin |
1519 | (method url-fetch) | |
1520 | (uri (bioconductor-uri "CGHcall" version)) | |
1521 | (sha256 | |
23177309 | 1522 | (base32 "13vzk4myizs94hyak4iyxdrqyxyq1g85hwsmd13892g8pww6ga93")))) |
67ee83d6 RJ |
1523 | (properties `((upstream-name . "CGHcall"))) |
1524 | (build-system r-build-system) | |
1525 | (propagated-inputs | |
1526 | `(("r-biobase" ,r-biobase) | |
1527 | ("r-cghbase" ,r-cghbase) | |
1528 | ("r-impute" ,r-impute) | |
1529 | ("r-dnacopy" ,r-dnacopy) | |
1530 | ("r-snowfall" ,r-snowfall))) | |
1531 | (home-page "http://bioconductor.org/packages/CGHcall") | |
1532 | (synopsis "Base functions and classes for arrayCGH data analysis") | |
1533 | (description "This package contains functions and classes that are needed by | |
1534 | @code{arrayCGH} packages.") | |
1535 | (license license:gpl2+))) | |
0ef8cc9c RJ |
1536 | |
1537 | (define-public r-qdnaseq | |
1538 | (package | |
1539 | (name "r-qdnaseq") | |
4f4bed7d | 1540 | (version "1.20.0") |
0ef8cc9c RJ |
1541 | (source (origin |
1542 | (method url-fetch) | |
1543 | (uri (bioconductor-uri "QDNAseq" version)) | |
1544 | (sha256 | |
4f4bed7d | 1545 | (base32 "02afy5bpj35981q1qm59jx399hksk6a9v1jfwy7x888rn86gfcfz")))) |
0ef8cc9c RJ |
1546 | (properties `((upstream-name . "QDNAseq"))) |
1547 | (build-system r-build-system) | |
1548 | (propagated-inputs | |
1549 | `(("r-biobase" ,r-biobase) | |
81b0181b | 1550 | ("r-biocparallel" ,r-biocparallel) |
0ef8cc9c RJ |
1551 | ("r-cghbase" ,r-cghbase) |
1552 | ("r-cghcall" ,r-cghcall) | |
1553 | ("r-dnacopy" ,r-dnacopy) | |
1554 | ("r-genomicranges" ,r-genomicranges) | |
1555 | ("r-iranges" ,r-iranges) | |
1556 | ("r-matrixstats" ,r-matrixstats) | |
1557 | ("r-r-utils" ,r-r-utils) | |
1558 | ("r-rsamtools" ,r-rsamtools))) | |
1559 | (home-page "http://bioconductor.org/packages/QDNAseq") | |
1560 | (synopsis "Quantitative DNA sequencing for chromosomal aberrations") | |
1561 | (description "The genome is divided into non-overlapping fixed-sized bins, | |
1562 | number of sequence reads in each counted, adjusted with a simultaneous | |
1563 | two-dimensional loess correction for sequence mappability and GC content, and | |
1564 | filtered to remove spurious regions in the genome. Downstream steps of | |
1565 | segmentation and calling are also implemented via packages DNAcopy and CGHcall, | |
1566 | respectively.") | |
1567 | (license license:gpl2+))) | |
bb15b581 RW |
1568 | |
1569 | (define-public r-bayseq | |
1570 | (package | |
1571 | (name "r-bayseq") | |
c38de815 | 1572 | (version "2.18.0") |
bb15b581 RW |
1573 | (source |
1574 | (origin | |
1575 | (method url-fetch) | |
1576 | (uri (bioconductor-uri "baySeq" version)) | |
1577 | (sha256 | |
1578 | (base32 | |
c38de815 | 1579 | "13lm7n5zqw8yg5sqb92h6ppcnr0l32qdgmv7i16pn32fb6z41p0w")))) |
bb15b581 RW |
1580 | (properties `((upstream-name . "baySeq"))) |
1581 | (build-system r-build-system) | |
1582 | (propagated-inputs | |
1583 | `(("r-abind" ,r-abind) | |
1584 | ("r-edger" ,r-edger) | |
1585 | ("r-genomicranges" ,r-genomicranges))) | |
1586 | (home-page "https://bioconductor.org/packages/baySeq/") | |
1587 | (synopsis "Bayesian analysis of differential expression patterns in count data") | |
1588 | (description | |
1589 | "This package identifies differential expression in high-throughput count | |
1590 | data, such as that derived from next-generation sequencing machines, | |
1591 | calculating estimated posterior likelihoods of differential expression (or | |
1592 | more complex hypotheses) via empirical Bayesian methods.") | |
1593 | (license license:gpl3))) | |
609f4ad1 RW |
1594 | |
1595 | (define-public r-chipcomp | |
1596 | (package | |
1597 | (name "r-chipcomp") | |
1ddd4af5 | 1598 | (version "1.14.0") |
609f4ad1 RW |
1599 | (source |
1600 | (origin | |
1601 | (method url-fetch) | |
1602 | (uri (bioconductor-uri "ChIPComp" version)) | |
1603 | (sha256 | |
1604 | (base32 | |
1ddd4af5 | 1605 | "0ragyl9dhg0ymgkh4z9d1cbwhbpcwh6x4985laaw6wmq2sjm732y")))) |
609f4ad1 RW |
1606 | (properties `((upstream-name . "ChIPComp"))) |
1607 | (build-system r-build-system) | |
1608 | (propagated-inputs | |
1609 | `(("r-biocgenerics" ,r-biocgenerics) | |
1610 | ("r-bsgenome-hsapiens-ucsc-hg19" ,r-bsgenome-hsapiens-ucsc-hg19) | |
1611 | ("r-bsgenome-mmusculus-ucsc-mm9" ,r-bsgenome-mmusculus-ucsc-mm9) | |
1612 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1613 | ("r-genomicranges" ,r-genomicranges) | |
1614 | ("r-iranges" ,r-iranges) | |
1615 | ("r-limma" ,r-limma) | |
1616 | ("r-rsamtools" ,r-rsamtools) | |
1617 | ("r-rtracklayer" ,r-rtracklayer) | |
1618 | ("r-s4vectors" ,r-s4vectors))) | |
1619 | (home-page "https://bioconductor.org/packages/ChIPComp") | |
1620 | (synopsis "Quantitative comparison of multiple ChIP-seq datasets") | |
1621 | (description | |
1622 | "ChIPComp implements a statistical method for quantitative comparison of | |
1623 | multiple ChIP-seq datasets. It detects differentially bound sharp binding | |
1624 | sites across multiple conditions considering matching control in ChIP-seq | |
1625 | datasets.") | |
1626 | ;; Any version of the GPL. | |
1627 | (license license:gpl3+))) | |
0490f9de RW |
1628 | |
1629 | (define-public r-riboprofiling | |
1630 | (package | |
1631 | (name "r-riboprofiling") | |
7d5acf7a | 1632 | (version "1.14.0") |
0490f9de RW |
1633 | (source |
1634 | (origin | |
1635 | (method url-fetch) | |
1636 | (uri (bioconductor-uri "RiboProfiling" version)) | |
1637 | (sha256 | |
1638 | (base32 | |
7d5acf7a | 1639 | "1si8zkznm0slvghk786qsp0wd6sns6hggrnz88ww9fcfvsqvzsy9")))) |
0490f9de RW |
1640 | (properties `((upstream-name . "RiboProfiling"))) |
1641 | (build-system r-build-system) | |
1642 | (propagated-inputs | |
1643 | `(("r-biocgenerics" ,r-biocgenerics) | |
1644 | ("r-biostrings" ,r-biostrings) | |
1645 | ("r-data-table" ,r-data-table) | |
1646 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1647 | ("r-genomicalignments" ,r-genomicalignments) | |
1648 | ("r-genomicfeatures" ,r-genomicfeatures) | |
1649 | ("r-genomicranges" ,r-genomicranges) | |
1650 | ("r-ggbio" ,r-ggbio) | |
1651 | ("r-ggplot2" ,r-ggplot2) | |
1652 | ("r-iranges" ,r-iranges) | |
1653 | ("r-plyr" ,r-plyr) | |
1654 | ("r-reshape2" ,r-reshape2) | |
1655 | ("r-rsamtools" ,r-rsamtools) | |
1656 | ("r-rtracklayer" ,r-rtracklayer) | |
1657 | ("r-s4vectors" ,r-s4vectors) | |
1658 | ("r-sqldf" ,r-sqldf))) | |
1659 | (home-page "https://bioconductor.org/packages/RiboProfiling/") | |
1660 | (synopsis "Ribosome profiling data analysis") | |
1661 | (description "Starting with a BAM file, this package provides the | |
1662 | necessary functions for quality assessment, read start position recalibration, | |
1663 | the counting of genomic sequence reads on CDS, 3'UTR, and 5'UTR, and plotting | |
1664 | of count data: pairs, log fold-change, codon frequency and coverage | |
1665 | assessment, principal component analysis on codon coverage.") | |
1666 | (license license:gpl3))) | |
6ffdfe6a RW |
1667 | |
1668 | (define-public r-riboseqr | |
1669 | (package | |
1670 | (name "r-riboseqr") | |
eff6b2eb | 1671 | (version "1.18.0") |
6ffdfe6a RW |
1672 | (source |
1673 | (origin | |
1674 | (method url-fetch) | |
1675 | (uri (bioconductor-uri "riboSeqR" version)) | |
1676 | (sha256 | |
1677 | (base32 | |
eff6b2eb | 1678 | "1d1v098w7fmnsmxfg3l7yndyyr7ajig00axiwg413lyg255is1ga")))) |
6ffdfe6a RW |
1679 | (properties `((upstream-name . "riboSeqR"))) |
1680 | (build-system r-build-system) | |
1681 | (propagated-inputs | |
1682 | `(("r-abind" ,r-abind) | |
1683 | ("r-bayseq" ,r-bayseq) | |
1684 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1685 | ("r-genomicranges" ,r-genomicranges) | |
1686 | ("r-iranges" ,r-iranges) | |
1687 | ("r-rsamtools" ,r-rsamtools) | |
1688 | ("r-seqlogo" ,r-seqlogo))) | |
1689 | (home-page "https://bioconductor.org/packages/riboSeqR/") | |
1690 | (synopsis "Analysis of sequencing data from ribosome profiling experiments") | |
1691 | (description | |
1692 | "This package provides plotting functions, frameshift detection and | |
1693 | parsing of genetic sequencing data from ribosome profiling experiments.") | |
1694 | (license license:gpl3))) | |
a32279ff RW |
1695 | |
1696 | (define-public r-interactionset | |
1697 | (package | |
1698 | (name "r-interactionset") | |
176a264c | 1699 | (version "1.12.0") |
a32279ff RW |
1700 | (source |
1701 | (origin | |
1702 | (method url-fetch) | |
1703 | (uri (bioconductor-uri "InteractionSet" version)) | |
1704 | (sha256 | |
1705 | (base32 | |
176a264c | 1706 | "0djgfpp34l6w8mk5b8s4wh0l12s4nn0f9ifvc3dq4970f6hb55z6")))) |
a32279ff RW |
1707 | (properties |
1708 | `((upstream-name . "InteractionSet"))) | |
1709 | (build-system r-build-system) | |
1710 | (propagated-inputs | |
1711 | `(("r-biocgenerics" ,r-biocgenerics) | |
1712 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1713 | ("r-genomicranges" ,r-genomicranges) | |
1714 | ("r-iranges" ,r-iranges) | |
1715 | ("r-matrix" ,r-matrix) | |
1716 | ("r-rcpp" ,r-rcpp) | |
1717 | ("r-s4vectors" ,r-s4vectors) | |
1718 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
1719 | (home-page "https://bioconductor.org/packages/InteractionSet") | |
1720 | (synopsis "Base classes for storing genomic interaction data") | |
1721 | (description | |
02fe0976 | 1722 | "This package provides the @code{GInteractions}, |
a32279ff RW |
1723 | @code{InteractionSet} and @code{ContactMatrix} objects and associated methods |
1724 | for storing and manipulating genomic interaction data from Hi-C and ChIA-PET | |
1725 | experiments.") | |
1726 | (license license:gpl3))) | |
cf9a29b2 RW |
1727 | |
1728 | (define-public r-genomicinteractions | |
1729 | (package | |
1730 | (name "r-genomicinteractions") | |
fcbd8960 | 1731 | (version "1.18.1") |
cf9a29b2 RW |
1732 | (source |
1733 | (origin | |
1734 | (method url-fetch) | |
1735 | (uri (bioconductor-uri "GenomicInteractions" version)) | |
1736 | (sha256 | |
1737 | (base32 | |
fcbd8960 | 1738 | "0hq2n5yfr9h2ayn10dy9lz08gd2q0awrm5cy2kqdmz4d8ss4r94p")))) |
cf9a29b2 RW |
1739 | (properties |
1740 | `((upstream-name . "GenomicInteractions"))) | |
1741 | (build-system r-build-system) | |
1742 | (propagated-inputs | |
1743 | `(("r-biobase" ,r-biobase) | |
1744 | ("r-biocgenerics" ,r-biocgenerics) | |
1745 | ("r-data-table" ,r-data-table) | |
1746 | ("r-dplyr" ,r-dplyr) | |
1747 | ("r-genomeinfodb" ,r-genomeinfodb) | |
1748 | ("r-genomicranges" ,r-genomicranges) | |
1749 | ("r-ggplot2" ,r-ggplot2) | |
1750 | ("r-gridextra" ,r-gridextra) | |
1751 | ("r-gviz" ,r-gviz) | |
1752 | ("r-igraph" ,r-igraph) | |
1753 | ("r-interactionset" ,r-interactionset) | |
1754 | ("r-iranges" ,r-iranges) | |
1755 | ("r-rsamtools" ,r-rsamtools) | |
1756 | ("r-rtracklayer" ,r-rtracklayer) | |
1757 | ("r-s4vectors" ,r-s4vectors) | |
1758 | ("r-stringr" ,r-stringr))) | |
1759 | (home-page "https://github.com/ComputationalRegulatoryGenomicsICL/GenomicInteractions/") | |
1760 | (synopsis "R package for handling genomic interaction data") | |
1761 | (description | |
1762 | "This R package provides tools for handling genomic interaction data, | |
1763 | such as ChIA-PET/Hi-C, annotating genomic features with interaction | |
1764 | information and producing various plots and statistics.") | |
1765 | (license license:gpl3))) | |
27c51606 RW |
1766 | |
1767 | (define-public r-ctc | |
1768 | (package | |
1769 | (name "r-ctc") | |
7a5d729a | 1770 | (version "1.58.0") |
27c51606 RW |
1771 | (source |
1772 | (origin | |
1773 | (method url-fetch) | |
1774 | (uri (bioconductor-uri "ctc" version)) | |
1775 | (sha256 | |
1776 | (base32 | |
7a5d729a | 1777 | "15n5b6i18x14km5rdqiydxcak5cr5dr3adwwwc5kcqf5gkwmi3am")))) |
27c51606 RW |
1778 | (build-system r-build-system) |
1779 | (propagated-inputs `(("r-amap" ,r-amap))) | |
1780 | (home-page "https://bioconductor.org/packages/ctc/") | |
1781 | (synopsis "Cluster and tree conversion") | |
1782 | (description | |
1783 | "This package provides tools for exporting and importing classification | |
1784 | trees and clusters to other programs.") | |
1785 | (license license:gpl2))) | |
5da0e142 RW |
1786 | |
1787 | (define-public r-goseq | |
1788 | (package | |
1789 | (name "r-goseq") | |
40f0ee43 | 1790 | (version "1.36.0") |
5da0e142 RW |
1791 | (source |
1792 | (origin | |
1793 | (method url-fetch) | |
1794 | (uri (bioconductor-uri "goseq" version)) | |
1795 | (sha256 | |
1796 | (base32 | |
40f0ee43 | 1797 | "0h8kd3d7yfdq8padfb0k92crwxi5h9gvgv4l3pa8k8wn4kczvciw")))) |
5da0e142 RW |
1798 | (build-system r-build-system) |
1799 | (propagated-inputs | |
1800 | `(("r-annotationdbi" ,r-annotationdbi) | |
1801 | ("r-biasedurn" ,r-biasedurn) | |
1802 | ("r-biocgenerics" ,r-biocgenerics) | |
1803 | ("r-genelendatabase" ,r-genelendatabase) | |
1804 | ("r-go-db" ,r-go-db) | |
1805 | ("r-mgcv" ,r-mgcv))) | |
1806 | (home-page "https://bioconductor.org/packages/goseq/") | |
1807 | (synopsis "Gene Ontology analyser for RNA-seq and other length biased data") | |
1808 | (description | |
1809 | "This package provides tools to detect Gene Ontology and/or other user | |
1810 | defined categories which are over/under represented in RNA-seq data.") | |
1811 | (license license:lgpl2.0+))) | |
f4235c0e RW |
1812 | |
1813 | (define-public r-glimma | |
1814 | (package | |
1815 | (name "r-glimma") | |
07252952 | 1816 | (version "1.12.0") |
f4235c0e RW |
1817 | (source |
1818 | (origin | |
1819 | (method url-fetch) | |
1820 | (uri (bioconductor-uri "Glimma" version)) | |
1821 | (sha256 | |
1822 | (base32 | |
07252952 | 1823 | "11qg5khqspxldfgg6p3xsxys472ab8wwi2snwc6bdxczv1f2p56x")))) |
f4235c0e RW |
1824 | (properties `((upstream-name . "Glimma"))) |
1825 | (build-system r-build-system) | |
1826 | (propagated-inputs | |
1827 | `(("r-edger" ,r-edger) | |
1828 | ("r-jsonlite" ,r-jsonlite) | |
1829 | ("r-s4vectors" ,r-s4vectors))) | |
1830 | (home-page "https://github.com/Shians/Glimma") | |
1831 | (synopsis "Interactive HTML graphics") | |
1832 | (description | |
1833 | "This package generates interactive visualisations for analysis of | |
1834 | RNA-sequencing data using output from limma, edgeR or DESeq2 packages in an | |
1835 | HTML page. The interactions are built on top of the popular static | |
1836 | representations of analysis results in order to provide additional | |
1837 | information.") | |
1838 | (license license:lgpl3))) | |
aa388dc7 RW |
1839 | |
1840 | (define-public r-rots | |
1841 | (package | |
1842 | (name "r-rots") | |
5bf7eb49 | 1843 | (version "1.12.0") |
aa388dc7 RW |
1844 | (source |
1845 | (origin | |
1846 | (method url-fetch) | |
1847 | (uri (bioconductor-uri "ROTS" version)) | |
1848 | (sha256 | |
1849 | (base32 | |
5bf7eb49 | 1850 | "1j29pfyv2pn0wp544m5a568b3yd31kzavwwiwqylcjwvq5lfzy77")))) |
aa388dc7 RW |
1851 | (properties `((upstream-name . "ROTS"))) |
1852 | (build-system r-build-system) | |
1853 | (propagated-inputs | |
1854 | `(("r-biobase" ,r-biobase) | |
1855 | ("r-rcpp" ,r-rcpp))) | |
1856 | (home-page "https://bioconductor.org/packages/ROTS/") | |
1857 | (synopsis "Reproducibility-Optimized Test Statistic") | |
1858 | (description | |
1859 | "This package provides tools for calculating the | |
1860 | @dfn{Reproducibility-Optimized Test Statistic} (ROTS) for differential testing | |
1861 | in omics data.") | |
1862 | (license license:gpl2+))) | |
b64ce4b7 | 1863 | |
cad6fb2d RW |
1864 | (define-public r-plgem |
1865 | (package | |
1866 | (name "r-plgem") | |
5dce7153 | 1867 | (version "1.56.0") |
cad6fb2d RW |
1868 | (source |
1869 | (origin | |
1870 | (method url-fetch) | |
1871 | (uri (bioconductor-uri "plgem" version)) | |
1872 | (sha256 | |
1873 | (base32 | |
5dce7153 | 1874 | "0y6gp5rlkvlv435qps7zhih84g5wrdvg6myj74ywnpl5a773nfqp")))) |
cad6fb2d RW |
1875 | (build-system r-build-system) |
1876 | (propagated-inputs | |
1877 | `(("r-biobase" ,r-biobase) | |
1878 | ("r-mass" ,r-mass))) | |
1879 | (home-page "http://www.genopolis.it") | |
1880 | (synopsis "Detect differential expression in microarray and proteomics datasets") | |
1881 | (description | |
1882 | "The Power Law Global Error Model (PLGEM) has been shown to faithfully | |
1883 | model the variance-versus-mean dependence that exists in a variety of | |
1884 | genome-wide datasets, including microarray and proteomics data. The use of | |
1885 | PLGEM has been shown to improve the detection of differentially expressed | |
1886 | genes or proteins in these datasets.") | |
1887 | (license license:gpl2))) | |
1888 | ||
b64ce4b7 RW |
1889 | (define-public r-inspect |
1890 | (package | |
1891 | (name "r-inspect") | |
3649d046 | 1892 | (version "1.14.0") |
b64ce4b7 RW |
1893 | (source |
1894 | (origin | |
1895 | (method url-fetch) | |
1896 | (uri (bioconductor-uri "INSPEcT" version)) | |
1897 | (sha256 | |
1898 | (base32 | |
3649d046 | 1899 | "1a7smljndiyahgpj6vl079pvi3n0rfk1vkdkp799y4nm2wnhn93r")))) |
b64ce4b7 RW |
1900 | (properties `((upstream-name . "INSPEcT"))) |
1901 | (build-system r-build-system) | |
1902 | (propagated-inputs | |
1903 | `(("r-biobase" ,r-biobase) | |
1904 | ("r-biocgenerics" ,r-biocgenerics) | |
1905 | ("r-biocparallel" ,r-biocparallel) | |
c86fc969 | 1906 | ("r-deseq2" ,r-deseq2) |
b64ce4b7 RW |
1907 | ("r-desolve" ,r-desolve) |
1908 | ("r-genomicalignments" ,r-genomicalignments) | |
1909 | ("r-genomicfeatures" ,r-genomicfeatures) | |
1910 | ("r-genomicranges" ,r-genomicranges) | |
1911 | ("r-iranges" ,r-iranges) | |
c86fc969 | 1912 | ("r-plgem" ,r-plgem) |
b64ce4b7 RW |
1913 | ("r-preprocesscore" ,r-preprocesscore) |
1914 | ("r-proc" ,r-proc) | |
1915 | ("r-rootsolve" ,r-rootsolve) | |
1916 | ("r-rsamtools" ,r-rsamtools) | |
c86fc969 RW |
1917 | ("r-s4vectors" ,r-s4vectors) |
1918 | ("r-shiny" ,r-shiny) | |
1919 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
1920 | ("r-txdb-mmusculus-ucsc-mm9-knowngene" | |
1921 | ,r-txdb-mmusculus-ucsc-mm9-knowngene))) | |
b64ce4b7 RW |
1922 | (home-page "https://bioconductor.org/packages/INSPEcT") |
1923 | (synopsis "Analysis of 4sU-seq and RNA-seq time-course data") | |
1924 | (description | |
1925 | "INSPEcT (INference of Synthesis, Processing and dEgradation rates in | |
1926 | Time-Course experiments) analyses 4sU-seq and RNA-seq time-course data in | |
1927 | order to evaluate synthesis, processing and degradation rates and assess via | |
1928 | modeling the rates that determines changes in mature mRNA levels.") | |
1929 | (license license:gpl2))) | |
f6e99763 RW |
1930 | |
1931 | (define-public r-dnabarcodes | |
1932 | (package | |
1933 | (name "r-dnabarcodes") | |
774e499c | 1934 | (version "1.14.0") |
f6e99763 RW |
1935 | (source |
1936 | (origin | |
1937 | (method url-fetch) | |
1938 | (uri (bioconductor-uri "DNABarcodes" version)) | |
1939 | (sha256 | |
1940 | (base32 | |
774e499c | 1941 | "1a0c9ag9n41cs0da9lfvpkxf7n5vbrfypaygdv66mw73aibix6v0")))) |
f6e99763 RW |
1942 | (properties `((upstream-name . "DNABarcodes"))) |
1943 | (build-system r-build-system) | |
1944 | (propagated-inputs | |
1945 | `(("r-bh" ,r-bh) | |
1946 | ("r-matrix" ,r-matrix) | |
1947 | ("r-rcpp" ,r-rcpp))) | |
1948 | (home-page "https://bioconductor.org/packages/DNABarcodes") | |
1949 | (synopsis "Create and analyze DNA barcodes") | |
1950 | (description | |
1951 | "This package offers tools to create DNA barcode sets capable of | |
1952 | correcting insertion, deletion, and substitution errors. Existing barcodes | |
1953 | can be analyzed regarding their minimal, maximal and average distances between | |
1954 | barcodes. Finally, reads that start with a (possibly mutated) barcode can be | |
1955 | demultiplexed, i.e. assigned to their original reference barcode.") | |
1956 | (license license:gpl2))) | |
09aa3d06 RW |
1957 | |
1958 | (define-public r-ruvseq | |
1959 | (package | |
1960 | (name "r-ruvseq") | |
d8771f5f | 1961 | (version "1.18.0") |
09aa3d06 RW |
1962 | (source |
1963 | (origin | |
1964 | (method url-fetch) | |
1965 | (uri (bioconductor-uri "RUVSeq" version)) | |
1966 | (sha256 | |
1967 | (base32 | |
d8771f5f | 1968 | "0ln4qc9d5r15zlhazx6annx97c0wrx3jqpcvk7yj1jnwh349lw33")))) |
09aa3d06 RW |
1969 | (properties `((upstream-name . "RUVSeq"))) |
1970 | (build-system r-build-system) | |
1971 | (propagated-inputs | |
1972 | `(("r-biobase" ,r-biobase) | |
1973 | ("r-edaseq" ,r-edaseq) | |
1974 | ("r-edger" ,r-edger) | |
1975 | ("r-mass" ,r-mass))) | |
1976 | (home-page "https://github.com/drisso/RUVSeq") | |
1977 | (synopsis "Remove unwanted variation from RNA-Seq data") | |
1978 | (description | |
1979 | "This package implements methods to @dfn{remove unwanted variation} (RUV) | |
1980 | of Risso et al. (2014) for the normalization of RNA-Seq read counts between | |
1981 | samples.") | |
1982 | (license license:artistic2.0))) | |
286157dc RW |
1983 | |
1984 | (define-public r-biocneighbors | |
1985 | (package | |
1986 | (name "r-biocneighbors") | |
6fc161fc | 1987 | (version "1.2.0") |
286157dc RW |
1988 | (source |
1989 | (origin | |
1990 | (method url-fetch) | |
1991 | (uri (bioconductor-uri "BiocNeighbors" version)) | |
1992 | (sha256 | |
1993 | (base32 | |
6fc161fc | 1994 | "08ak72y6mafzkhzfkx6b7waljpa0f1nxcrvyspd88sgzxgxjnkmg")))) |
286157dc RW |
1995 | (properties `((upstream-name . "BiocNeighbors"))) |
1996 | (build-system r-build-system) | |
1997 | (propagated-inputs | |
6fc161fc RW |
1998 | `(("r-biocgenerics" ,r-biocgenerics) |
1999 | ("r-biocparallel" ,r-biocparallel) | |
286157dc RW |
2000 | ("r-rcpp" ,r-rcpp) |
2001 | ("r-rcppannoy" ,r-rcppannoy) | |
6fc161fc | 2002 | ("r-rcpphnsw" ,r-rcpphnsw) |
286157dc RW |
2003 | ("r-s4vectors" ,r-s4vectors))) |
2004 | (home-page "https://bioconductor.org/packages/BiocNeighbors") | |
2005 | (synopsis "Nearest Neighbor Detection for Bioconductor packages") | |
2006 | (description | |
2007 | "This package implements exact and approximate methods for nearest | |
2008 | neighbor detection, in a framework that allows them to be easily switched | |
2009 | within Bioconductor packages or workflows. The exact algorithm is implemented | |
2010 | using pre-clustering with the k-means algorithm. Functions are also provided | |
2011 | to search for all neighbors within a given distance. Parallelization is | |
2012 | achieved for all methods using the BiocParallel framework.") | |
2013 | (license license:gpl3))) | |
8a587c89 | 2014 | |
99391290 RW |
2015 | (define-public r-biocsingular |
2016 | (package | |
2017 | (name "r-biocsingular") | |
2018 | (version "1.0.0") | |
2019 | (source | |
2020 | (origin | |
2021 | (method url-fetch) | |
2022 | (uri (bioconductor-uri "BiocSingular" version)) | |
2023 | (sha256 | |
2024 | (base32 | |
2025 | "129z6bkdhm5wlvrjiwrr8yl2jj9chh4i6dm6firlj4c4ql3jp4f5")))) | |
2026 | (properties `((upstream-name . "BiocSingular"))) | |
2027 | (build-system r-build-system) | |
2028 | (propagated-inputs | |
2029 | `(("r-beachmat" ,r-beachmat) | |
2030 | ("r-biocgenerics" ,r-biocgenerics) | |
2031 | ("r-biocparallel" ,r-biocparallel) | |
2032 | ("r-delayedarray" ,r-delayedarray) | |
2033 | ("r-irlba" ,r-irlba) | |
2034 | ("r-matrix" ,r-matrix) | |
2035 | ("r-rcpp" ,r-rcpp) | |
2036 | ("r-rsvd" ,r-rsvd) | |
2037 | ("r-s4vectors" ,r-s4vectors))) | |
2038 | (home-page "https://github.com/LTLA/BiocSingular") | |
2039 | (synopsis "Singular value decomposition for Bioconductor packages") | |
2040 | (description | |
2041 | "This package implements exact and approximate methods for singular value | |
2042 | decomposition and principal components analysis, in a framework that allows | |
2043 | them to be easily switched within Bioconductor packages or workflows. Where | |
2044 | possible, parallelization is achieved using the BiocParallel framework.") | |
2045 | (license license:gpl3))) | |
2046 | ||
a961ae46 RW |
2047 | (define-public r-destiny |
2048 | (package | |
2049 | (name "r-destiny") | |
0aa72f2d | 2050 | (version "2.14.0") |
a961ae46 RW |
2051 | (source |
2052 | (origin | |
2053 | (method url-fetch) | |
2054 | (uri (bioconductor-uri "destiny" version)) | |
2055 | (sha256 | |
2056 | (base32 | |
0aa72f2d | 2057 | "1bpa114fgrknn6415g4d1jrvb924nkwi18jzfqribpvcf1vlgrf3")))) |
a961ae46 RW |
2058 | (build-system r-build-system) |
2059 | (propagated-inputs | |
2060 | `(("r-biobase" ,r-biobase) | |
2061 | ("r-biocgenerics" ,r-biocgenerics) | |
0aa72f2d | 2062 | ("r-ggplot2" ,r-ggplot2) |
a961ae46 | 2063 | ("r-ggthemes" ,r-ggthemes) |
a961ae46 RW |
2064 | ("r-igraph" ,r-igraph) |
2065 | ("r-matrix" ,r-matrix) | |
2066 | ("r-proxy" ,r-proxy) | |
2067 | ("r-rcpp" ,r-rcpp) | |
2068 | ("r-rcppeigen" ,r-rcppeigen) | |
2069 | ("r-scales" ,r-scales) | |
2070 | ("r-scatterplot3d" ,r-scatterplot3d) | |
2071 | ("r-smoother" ,r-smoother) | |
2072 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
2073 | ("r-vim" ,r-vim))) | |
2074 | (home-page "https://bioconductor.org/packages/destiny/") | |
2075 | (synopsis "Create and plot diffusion maps") | |
2076 | (description "This package provides tools to create and plot diffusion | |
2077 | maps.") | |
2078 | ;; Any version of the GPL | |
2079 | (license license:gpl3+))) | |
2080 | ||
8a587c89 RW |
2081 | (define-public r-savr |
2082 | (package | |
2083 | (name "r-savr") | |
8d3d0c3a | 2084 | (version "1.22.0") |
8a587c89 RW |
2085 | (source |
2086 | (origin | |
2087 | (method url-fetch) | |
2088 | (uri (bioconductor-uri "savR" version)) | |
2089 | (sha256 | |
2090 | (base32 | |
8d3d0c3a | 2091 | "101p0c07p49c50lfnbfanyyikdypmqkvwclqifq32js9phqwhf6h")))) |
8a587c89 RW |
2092 | (properties `((upstream-name . "savR"))) |
2093 | (build-system r-build-system) | |
2094 | (propagated-inputs | |
2095 | `(("r-ggplot2" ,r-ggplot2) | |
2096 | ("r-gridextra" ,r-gridextra) | |
2097 | ("r-reshape2" ,r-reshape2) | |
2098 | ("r-scales" ,r-scales) | |
2099 | ("r-xml" ,r-xml))) | |
2100 | (home-page "https://github.com/bcalder/savR") | |
2101 | (synopsis "Parse and analyze Illumina SAV files") | |
2102 | (description | |
2103 | "This package provides tools to parse Illumina Sequence Analysis | |
2104 | Viewer (SAV) files, access data, and generate QC plots.") | |
2105 | (license license:agpl3+))) | |
41ffc214 RW |
2106 | |
2107 | (define-public r-chipexoqual | |
2108 | (package | |
2109 | (name "r-chipexoqual") | |
58a43fc2 | 2110 | (version "1.8.0") |
41ffc214 RW |
2111 | (source |
2112 | (origin | |
2113 | (method url-fetch) | |
2114 | (uri (bioconductor-uri "ChIPexoQual" version)) | |
2115 | (sha256 | |
2116 | (base32 | |
58a43fc2 | 2117 | "02341i3lg74czgapf5qc6zvi2321af3rp85qavbg209fyc219acj")))) |
41ffc214 RW |
2118 | (properties `((upstream-name . "ChIPexoQual"))) |
2119 | (build-system r-build-system) | |
2120 | (propagated-inputs | |
2121 | `(("r-biocparallel" ,r-biocparallel) | |
2122 | ("r-biovizbase" ,r-biovizbase) | |
2123 | ("r-broom" ,r-broom) | |
2124 | ("r-data-table" ,r-data-table) | |
2125 | ("r-dplyr" ,r-dplyr) | |
2126 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2127 | ("r-genomicalignments" ,r-genomicalignments) | |
2128 | ("r-genomicranges" ,r-genomicranges) | |
2129 | ("r-ggplot2" ,r-ggplot2) | |
2130 | ("r-hexbin" ,r-hexbin) | |
2131 | ("r-iranges" ,r-iranges) | |
2132 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
2133 | ("r-rmarkdown" ,r-rmarkdown) | |
2134 | ("r-rsamtools" ,r-rsamtools) | |
2135 | ("r-s4vectors" ,r-s4vectors) | |
2136 | ("r-scales" ,r-scales) | |
2137 | ("r-viridis" ,r-viridis))) | |
2138 | (home-page "https://github.com/keleslab/ChIPexoQual") | |
2139 | (synopsis "Quality control pipeline for ChIP-exo/nexus data") | |
2140 | (description | |
2141 | "This package provides a quality control pipeline for ChIP-exo/nexus | |
2142 | sequencing data.") | |
2143 | (license license:gpl2+))) | |
c18dccff | 2144 | |
3d13b448 RW |
2145 | (define-public r-copynumber |
2146 | (package | |
2147 | (name "r-copynumber") | |
d9419185 | 2148 | (version "1.24.0") |
3d13b448 RW |
2149 | (source (origin |
2150 | (method url-fetch) | |
2151 | (uri (bioconductor-uri "copynumber" version)) | |
2152 | (sha256 | |
2153 | (base32 | |
d9419185 | 2154 | "0gmxi7w776pjqv3v0pkdihb167zzrnr9hw64yfvzgjhkhrc6a4rp")))) |
3d13b448 RW |
2155 | (build-system r-build-system) |
2156 | (propagated-inputs | |
2157 | `(("r-s4vectors" ,r-s4vectors) | |
2158 | ("r-iranges" ,r-iranges) | |
2159 | ("r-genomicranges" ,r-genomicranges) | |
2160 | ("r-biocgenerics" ,r-biocgenerics))) | |
2161 | (home-page "https://bioconductor.org/packages/copynumber") | |
2162 | (synopsis "Segmentation of single- and multi-track copy number data") | |
2163 | (description | |
2164 | "This package segments single- and multi-track copy number data by a | |
2165 | penalized least squares regression method.") | |
2166 | (license license:artistic2.0))) | |
2167 | ||
c18dccff RW |
2168 | (define-public r-dnacopy |
2169 | (package | |
2170 | (name "r-dnacopy") | |
d5f3c0d0 | 2171 | (version "1.58.0") |
c18dccff RW |
2172 | (source |
2173 | (origin | |
2174 | (method url-fetch) | |
2175 | (uri (bioconductor-uri "DNAcopy" version)) | |
2176 | (sha256 | |
2177 | (base32 | |
d5f3c0d0 | 2178 | "1gybr3cbsrqjgz00n4l5kb2nrmh302xpvzk5zk957ijj5qbfwmxa")))) |
c18dccff RW |
2179 | (properties `((upstream-name . "DNAcopy"))) |
2180 | (build-system r-build-system) | |
2181 | (native-inputs `(("gfortran" ,gfortran))) | |
2182 | (home-page "https://bioconductor.org/packages/DNAcopy") | |
2183 | (synopsis "DNA copy number data analysis") | |
2184 | (description | |
2185 | "This package implements the @dfn{circular binary segmentation} (CBS) | |
2186 | algorithm to segment DNA copy number data and identify genomic regions with | |
2187 | abnormal copy number.") | |
2188 | (license license:gpl2+))) | |
3a0babac RW |
2189 | |
2190 | ;; This is a CRAN package, but it uncharacteristically depends on a | |
2191 | ;; Bioconductor package. | |
2192 | (define-public r-htscluster | |
2193 | (package | |
2194 | (name "r-htscluster") | |
2195 | (version "2.0.8") | |
2196 | (source | |
2197 | (origin | |
2198 | (method url-fetch) | |
2199 | (uri (cran-uri "HTSCluster" version)) | |
2200 | (sha256 | |
2201 | (base32 | |
2202 | "0wnbfh6hdx8692jilgmv8sys1zm6fqc6mim7vvjhyqlmpm8gm0kg")))) | |
2203 | (properties `((upstream-name . "HTSCluster"))) | |
2204 | (build-system r-build-system) | |
2205 | (propagated-inputs | |
2206 | `(("r-capushe" ,r-capushe) | |
2207 | ("r-edger" ,r-edger) | |
2208 | ("r-plotrix" ,r-plotrix))) | |
2209 | (home-page "https://cran.r-project.org/web/packages/HTSCluster") | |
2210 | (synopsis "Clustering high-throughput transcriptome sequencing (HTS) data") | |
2211 | (description | |
2212 | "This package provides a Poisson mixture model is implemented to cluster | |
2213 | genes from high-throughput transcriptome sequencing (RNA-seq) data. Parameter | |
2214 | estimation is performed using either the EM or CEM algorithm, and the slope | |
2215 | heuristics are used for model selection (i.e., to choose the number of | |
2216 | clusters).") | |
2217 | (license license:gpl3+))) | |
173c9960 RW |
2218 | |
2219 | (define-public r-deds | |
2220 | (package | |
2221 | (name "r-deds") | |
301c4ff1 | 2222 | (version "1.58.0") |
173c9960 RW |
2223 | (source |
2224 | (origin | |
2225 | (method url-fetch) | |
2226 | (uri (bioconductor-uri "DEDS" version)) | |
2227 | (sha256 | |
2228 | (base32 | |
301c4ff1 | 2229 | "029g7wgxc7yp1cdyalbi8gipkskrgp7nyl1s2whhjy5dqpfcpigs")))) |
173c9960 RW |
2230 | (properties `((upstream-name . "DEDS"))) |
2231 | (build-system r-build-system) | |
2232 | (home-page "https://bioconductor.org/packages/DEDS/") | |
2233 | (synopsis "Differential expression via distance summary for microarray data") | |
2234 | (description | |
2235 | "This library contains functions that calculate various statistics of | |
2236 | differential expression for microarray data, including t statistics, fold | |
2237 | change, F statistics, SAM, moderated t and F statistics and B statistics. It | |
2238 | also implements a new methodology called DEDS (Differential Expression via | |
2239 | Distance Summary), which selects differentially expressed genes by integrating | |
2240 | and summarizing a set of statistics using a weighted distance approach.") | |
2241 | ;; Any version of the LGPL. | |
2242 | (license license:lgpl3+))) | |
7ed869f7 RW |
2243 | |
2244 | ;; This is a CRAN package, but since it depends on a Bioconductor package we | |
2245 | ;; put it here. | |
2246 | (define-public r-nbpseq | |
2247 | (package | |
2248 | (name "r-nbpseq") | |
2249 | (version "0.3.0") | |
2250 | (source | |
2251 | (origin | |
2252 | (method url-fetch) | |
2253 | (uri (cran-uri "NBPSeq" version)) | |
2254 | (sha256 | |
2255 | (base32 | |
2256 | "0l4ylxhs2k9ww21jjqs67fygk92avdchhx2y1ixzl7yr2yh1y9by")))) | |
2257 | (properties `((upstream-name . "NBPSeq"))) | |
2258 | (build-system r-build-system) | |
2259 | (propagated-inputs | |
2260 | `(("r-qvalue" ,r-qvalue))) | |
2261 | (home-page "https://cran.r-project.org/web/packages/NBPSeq") | |
2262 | (synopsis "Negative binomial models for RNA-Seq data") | |
2263 | (description | |
2264 | "This package provides negative binomial models for two-group comparisons | |
2265 | and regression inferences from RNA-sequencing data.") | |
2266 | (license license:gpl2))) | |
3087a2f3 RW |
2267 | |
2268 | (define-public r-ebseq | |
2269 | (package | |
2270 | (name "r-ebseq") | |
4a3c47e9 | 2271 | (version "1.24.0") |
3087a2f3 RW |
2272 | (source |
2273 | (origin | |
2274 | (method url-fetch) | |
2275 | (uri (bioconductor-uri "EBSeq" version)) | |
2276 | (sha256 | |
2277 | (base32 | |
4a3c47e9 | 2278 | "13rf85gffqn86r5gqibla3gqrnnag2zinrfawpcsgn3fk7hl3v83")))) |
3087a2f3 RW |
2279 | (properties `((upstream-name . "EBSeq"))) |
2280 | (build-system r-build-system) | |
2281 | (propagated-inputs | |
2282 | `(("r-blockmodeling" ,r-blockmodeling) | |
2283 | ("r-gplots" ,r-gplots) | |
2284 | ("r-testthat" ,r-testthat))) | |
2285 | (home-page "https://bioconductor.org/packages/EBSeq") | |
2286 | (synopsis "Differential expression analysis of RNA-seq data") | |
2287 | (description | |
2288 | "This package provides tools for differential expression analysis at both | |
2289 | gene and isoform level using RNA-seq data") | |
2290 | (license license:artistic2.0))) | |
2cb71d81 RW |
2291 | |
2292 | (define-public r-lpsymphony | |
2293 | (package | |
2294 | (name "r-lpsymphony") | |
61c79d55 | 2295 | (version "1.12.0") |
2cb71d81 RW |
2296 | (source |
2297 | (origin | |
2298 | (method url-fetch) | |
2299 | (uri (bioconductor-uri "lpsymphony" version)) | |
2300 | (sha256 | |
2301 | (base32 | |
61c79d55 | 2302 | "13wvq4ip8nkyxmpncs6fzcf3vphra1n0fd5vz9kspbch0k1z6bsv")))) |
2cb71d81 RW |
2303 | (build-system r-build-system) |
2304 | (inputs | |
2305 | `(("gfortran" ,gfortran) | |
2306 | ("zlib" ,zlib))) | |
2307 | (native-inputs | |
2308 | `(("pkg-config" ,pkg-config))) | |
2309 | (home-page "http://r-forge.r-project.org/projects/rsymphony") | |
2310 | (synopsis "Symphony integer linear programming solver in R") | |
2311 | (description | |
2312 | "This package was derived from Rsymphony. The package provides an R | |
2313 | interface to SYMPHONY, a linear programming solver written in C++. The main | |
2314 | difference between this package and Rsymphony is that it includes the solver | |
2315 | source code, while Rsymphony expects to find header and library files on the | |
2316 | users' system. Thus the intention of @code{lpsymphony} is to provide an easy | |
2317 | to install interface to SYMPHONY.") | |
2318 | ;; Symphony 5.4 or later is distributed under the terms of the EPL 1.0. | |
2319 | ;; lpsimphony is released under the same terms. | |
2320 | (license license:epl1.0))) | |
704de8f5 RW |
2321 | |
2322 | (define-public r-ihw | |
2323 | (package | |
2324 | (name "r-ihw") | |
bcd8b7a9 | 2325 | (version "1.12.0") |
704de8f5 RW |
2326 | (source |
2327 | (origin | |
2328 | (method url-fetch) | |
2329 | (uri (bioconductor-uri "IHW" version)) | |
2330 | (sha256 | |
2331 | (base32 | |
bcd8b7a9 | 2332 | "05hs6w1albkbyqzkid0bchb5zs41f31a7vhfbcswryhc86cxwzkz")))) |
704de8f5 RW |
2333 | (properties `((upstream-name . "IHW"))) |
2334 | (build-system r-build-system) | |
2335 | (propagated-inputs | |
2336 | `(("r-biocgenerics" ,r-biocgenerics) | |
2337 | ("r-fdrtool" ,r-fdrtool) | |
2338 | ("r-lpsymphony" ,r-lpsymphony) | |
2339 | ("r-slam" ,r-slam))) | |
2340 | (home-page "https://bioconductor.org/packages/IHW") | |
2341 | (synopsis "Independent hypothesis weighting") | |
2342 | (description | |
2343 | "@dfn{Independent hypothesis weighting} (IHW) is a multiple testing | |
2344 | procedure that increases power compared to the method of Benjamini and | |
2345 | Hochberg by assigning data-driven weights to each hypothesis. The input to | |
2346 | IHW is a two-column table of p-values and covariates. The covariate can be | |
2347 | any continuous-valued or categorical variable that is thought to be | |
2348 | informative on the statistical properties of each hypothesis test, while it is | |
2349 | independent of the p-value under the null hypothesis.") | |
2350 | (license license:artistic2.0))) | |
251e0830 RW |
2351 | |
2352 | (define-public r-icobra | |
2353 | (package | |
2354 | (name "r-icobra") | |
13b49976 | 2355 | (version "1.12.1") |
251e0830 RW |
2356 | (source |
2357 | (origin | |
2358 | (method url-fetch) | |
2359 | (uri (bioconductor-uri "iCOBRA" version)) | |
2360 | (sha256 | |
2361 | (base32 | |
13b49976 | 2362 | "1wj0vqyb6h4rddmn4va3182yap9bv4m1r1jlzyjfyrqxhl2sqb1q")))) |
251e0830 RW |
2363 | (properties `((upstream-name . "iCOBRA"))) |
2364 | (build-system r-build-system) | |
2365 | (propagated-inputs | |
2366 | `(("r-dplyr" ,r-dplyr) | |
2367 | ("r-dt" ,r-dt) | |
2368 | ("r-ggplot2" ,r-ggplot2) | |
2369 | ("r-limma" ,r-limma) | |
2370 | ("r-reshape2" ,r-reshape2) | |
2371 | ("r-rocr" ,r-rocr) | |
2372 | ("r-scales" ,r-scales) | |
2373 | ("r-shiny" ,r-shiny) | |
2374 | ("r-shinybs" ,r-shinybs) | |
2375 | ("r-shinydashboard" ,r-shinydashboard) | |
2376 | ("r-upsetr" ,r-upsetr))) | |
2377 | (home-page "https://bioconductor.org/packages/iCOBRA") | |
2378 | (synopsis "Comparison and visualization of ranking and assignment methods") | |
2379 | (description | |
2380 | "This package provides functions for calculation and visualization of | |
2381 | performance metrics for evaluation of ranking and binary | |
2382 | classification (assignment) methods. It also contains a Shiny application for | |
2383 | interactive exploration of results.") | |
2384 | (license license:gpl2+))) | |
925fcdbb RW |
2385 | |
2386 | (define-public r-mast | |
2387 | (package | |
2388 | (name "r-mast") | |
a0ff725d | 2389 | (version "1.10.0") |
925fcdbb RW |
2390 | (source |
2391 | (origin | |
2392 | (method url-fetch) | |
2393 | (uri (bioconductor-uri "MAST" version)) | |
2394 | (sha256 | |
2395 | (base32 | |
a0ff725d | 2396 | "0f2qkp346095k9m45frpd3bivrvaps9wlm0m3n0z8j0aj7w1kqlx")))) |
925fcdbb RW |
2397 | (properties `((upstream-name . "MAST"))) |
2398 | (build-system r-build-system) | |
2399 | (propagated-inputs | |
2400 | `(("r-abind" ,r-abind) | |
a0ff725d | 2401 | ("r-blme" ,r-blme) |
925fcdbb RW |
2402 | ("r-biobase" ,r-biobase) |
2403 | ("r-biocgenerics" ,r-biocgenerics) | |
2404 | ("r-data-table" ,r-data-table) | |
2405 | ("r-ggplot2" ,r-ggplot2) | |
2406 | ("r-plyr" ,r-plyr) | |
2407 | ("r-progress" ,r-progress) | |
2408 | ("r-reshape2" ,r-reshape2) | |
2409 | ("r-s4vectors" ,r-s4vectors) | |
2410 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2411 | ("r-stringr" ,r-stringr) | |
2412 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2413 | (home-page "https://github.com/RGLab/MAST/") | |
2414 | (synopsis "Model-based analysis of single cell transcriptomics") | |
2415 | (description | |
2416 | "This package provides methods and models for handling zero-inflated | |
2417 | single cell assay data.") | |
2418 | (license license:gpl2+))) | |
2d7627cf RW |
2419 | |
2420 | (define-public r-monocle | |
2421 | (package | |
2422 | (name "r-monocle") | |
78b63267 | 2423 | (version "2.12.0") |
2d7627cf RW |
2424 | (source |
2425 | (origin | |
2426 | (method url-fetch) | |
2427 | (uri (bioconductor-uri "monocle" version)) | |
2428 | (sha256 | |
2429 | (base32 | |
78b63267 | 2430 | "1rnr3k0wc61a806w9flapni91wz5xm0l66jabjzx0vbiwgczs32z")))) |
2d7627cf RW |
2431 | (build-system r-build-system) |
2432 | (propagated-inputs | |
2433 | `(("r-biobase" ,r-biobase) | |
2434 | ("r-biocgenerics" ,r-biocgenerics) | |
2435 | ("r-biocviews" ,r-biocviews) | |
2436 | ("r-cluster" ,r-cluster) | |
2437 | ("r-combinat" ,r-combinat) | |
2438 | ("r-ddrtree" ,r-ddrtree) | |
2439 | ("r-densityclust" ,r-densityclust) | |
2440 | ("r-dplyr" ,r-dplyr) | |
2441 | ("r-fastica" ,r-fastica) | |
2442 | ("r-ggplot2" ,r-ggplot2) | |
2443 | ("r-hsmmsinglecell" ,r-hsmmsinglecell) | |
2444 | ("r-igraph" ,r-igraph) | |
2445 | ("r-irlba" ,r-irlba) | |
2446 | ("r-limma" ,r-limma) | |
2447 | ("r-mass" ,r-mass) | |
2448 | ("r-matrix" ,r-matrix) | |
2449 | ("r-matrixstats" ,r-matrixstats) | |
2450 | ("r-pheatmap" ,r-pheatmap) | |
2451 | ("r-plyr" ,r-plyr) | |
2452 | ("r-proxy" ,r-proxy) | |
2453 | ("r-qlcmatrix" ,r-qlcmatrix) | |
2454 | ("r-rann" ,r-rann) | |
2455 | ("r-rcpp" ,r-rcpp) | |
2456 | ("r-reshape2" ,r-reshape2) | |
2457 | ("r-rtsne" ,r-rtsne) | |
2458 | ("r-slam" ,r-slam) | |
2459 | ("r-stringr" ,r-stringr) | |
2460 | ("r-tibble" ,r-tibble) | |
2461 | ("r-vgam" ,r-vgam) | |
2462 | ("r-viridis" ,r-viridis))) | |
2463 | (home-page "https://bioconductor.org/packages/monocle") | |
2464 | (synopsis "Clustering, differential expression, and trajectory analysis for single-cell RNA-Seq") | |
2465 | (description | |
2466 | "Monocle performs differential expression and time-series analysis for | |
2467 | single-cell expression experiments. It orders individual cells according to | |
2468 | progress through a biological process, without knowing ahead of time which | |
2469 | genes define progress through that process. Monocle also performs | |
2470 | differential expression analysis, clustering, visualization, and other useful | |
2471 | tasks on single cell expression data. It is designed to work with RNA-Seq and | |
2472 | qPCR data, but could be used with other types as well.") | |
2473 | (license license:artistic2.0))) | |
6213e441 | 2474 | |
b2dce6b5 RW |
2475 | (define-public r-monocle3 |
2476 | (package | |
2477 | (name "r-monocle3") | |
2478 | (version "0.1.2") | |
2479 | (source | |
2480 | (origin | |
2481 | (method git-fetch) | |
2482 | (uri (git-reference | |
2483 | (url "https://github.com/cole-trapnell-lab/monocle3.git") | |
2484 | (commit version))) | |
2485 | (file-name (git-file-name name version)) | |
2486 | (sha256 | |
2487 | (base32 | |
2488 | "1cjxqfw3qvy269hsf5v80d4kshl932wrl949iayas02saj6f70ls")))) | |
2489 | (build-system r-build-system) | |
2490 | (propagated-inputs | |
2491 | `(("r-biobase" ,r-biobase) | |
2492 | ("r-biocgenerics" ,r-biocgenerics) | |
2493 | ("r-delayedmatrixstats" ,r-delayedmatrixstats) | |
2494 | ("r-dplyr" ,r-dplyr) | |
2495 | ("r-ggplot2" ,r-ggplot2) | |
2496 | ("r-ggrepel" ,r-ggrepel) | |
2497 | ("r-grr" ,r-grr) | |
2498 | ("r-htmlwidgets" ,r-htmlwidgets) | |
2499 | ("r-igraph" ,r-igraph) | |
2500 | ("r-irlba" ,r-irlba) | |
2501 | ("r-limma" ,r-limma) | |
2502 | ("r-lmtest" ,r-lmtest) | |
2503 | ("r-mass" ,r-mass) | |
2504 | ("r-matrix" ,r-matrix) | |
2505 | ("r-matrix-utils" ,r-matrix-utils) | |
2506 | ("r-pbapply" ,r-pbapply) | |
2507 | ("r-pbmcapply" ,r-pbmcapply) | |
2508 | ("r-pheatmap" ,r-pheatmap) | |
2509 | ("r-plotly" ,r-plotly) | |
2510 | ("r-pryr" ,r-pryr) | |
2511 | ("r-proxy" ,r-proxy) | |
2512 | ("r-pscl" ,r-pscl) | |
2513 | ("r-purrr" ,r-purrr) | |
2514 | ("r-rann" ,r-rann) | |
2515 | ("r-rcpp" ,r-rcpp) | |
2516 | ("r-rcppparallel" ,r-rcppparallel) | |
2517 | ("r-reshape2" ,r-reshape2) | |
2518 | ("r-reticulate" ,r-reticulate) | |
2519 | ("r-rhpcblasctl" ,r-rhpcblasctl) | |
2520 | ("r-rtsne" ,r-rtsne) | |
2521 | ("r-shiny" ,r-shiny) | |
2522 | ("r-slam" ,r-slam) | |
2523 | ("r-spdep" ,r-spdep) | |
2524 | ("r-speedglm" ,r-speedglm) | |
2525 | ("r-stringr" ,r-stringr) | |
2526 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2527 | ("r-tibble" ,r-tibble) | |
2528 | ("r-tidyr" ,r-tidyr) | |
2529 | ("r-uwot" ,r-uwot) | |
2530 | ("r-viridis" ,r-viridis))) | |
2531 | (home-page "https://github.com/cole-trapnell-lab/monocle3") | |
2532 | (synopsis "Analysis toolkit for single-cell RNA-Seq data") | |
2533 | (description | |
2534 | "Monocle 3 is an analysis toolkit for single-cell RNA-Seq experiments.") | |
2535 | (license license:expat))) | |
2536 | ||
6213e441 RW |
2537 | (define-public r-noiseq |
2538 | (package | |
2539 | (name "r-noiseq") | |
6a2c58b7 | 2540 | (version "2.28.0") |
6213e441 RW |
2541 | (source |
2542 | (origin | |
2543 | (method url-fetch) | |
2544 | (uri (bioconductor-uri "NOISeq" version)) | |
2545 | (sha256 | |
2546 | (base32 | |
6a2c58b7 | 2547 | "1k7k0xqa0lxj6mfsvbmd6x6glv9wynbwl87w5d3bilbq4dpc139j")))) |
6213e441 RW |
2548 | (properties `((upstream-name . "NOISeq"))) |
2549 | (build-system r-build-system) | |
2550 | (propagated-inputs | |
2551 | `(("r-biobase" ,r-biobase) | |
2552 | ("r-matrix" ,r-matrix))) | |
2553 | (home-page "https://bioconductor.org/packages/NOISeq") | |
2554 | (synopsis "Exploratory analysis and differential expression for RNA-seq data") | |
2555 | (description | |
2556 | "This package provides tools to support the analysis of RNA-seq | |
2557 | expression data or other similar kind of data. It provides exploratory plots | |
2558 | to evaluate saturation, count distribution, expression per chromosome, type of | |
2559 | detected features, features length, etc. It also supports the analysis of | |
2560 | differential expression between two experimental conditions with no parametric | |
2561 | assumptions.") | |
2562 | (license license:artistic2.0))) | |
b409c357 RW |
2563 | |
2564 | (define-public r-scdd | |
2565 | (package | |
2566 | (name "r-scdd") | |
7baa59ed | 2567 | (version "1.8.0") |
b409c357 RW |
2568 | (source |
2569 | (origin | |
2570 | (method url-fetch) | |
2571 | (uri (bioconductor-uri "scDD" version)) | |
2572 | (sha256 | |
2573 | (base32 | |
7baa59ed | 2574 | "01hp6xxxap7541yi5dv596xvamqyyihvgkdy224ixa0n2cxyrhyf")))) |
b409c357 RW |
2575 | (properties `((upstream-name . "scDD"))) |
2576 | (build-system r-build-system) | |
2577 | (propagated-inputs | |
2578 | `(("r-arm" ,r-arm) | |
2579 | ("r-biocparallel" ,r-biocparallel) | |
2580 | ("r-ebseq" ,r-ebseq) | |
2581 | ("r-fields" ,r-fields) | |
2582 | ("r-ggplot2" ,r-ggplot2) | |
2583 | ("r-mclust" ,r-mclust) | |
2584 | ("r-outliers" ,r-outliers) | |
2585 | ("r-s4vectors" ,r-s4vectors) | |
2586 | ("r-scran" ,r-scran) | |
2587 | ("r-singlecellexperiment" ,r-singlecellexperiment) | |
2588 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2589 | (home-page "https://github.com/kdkorthauer/scDD") | |
2590 | (synopsis "Mixture modeling of single-cell RNA-seq data") | |
2591 | (description | |
2592 | "This package implements a method to analyze single-cell RNA-seq data | |
2593 | utilizing flexible Dirichlet Process mixture models. Genes with differential | |
2594 | distributions of expression are classified into several interesting patterns | |
2595 | of differences between two conditions. The package also includes functions | |
2596 | for simulating data with these patterns from negative binomial | |
2597 | distributions.") | |
2598 | (license license:gpl2))) | |
f0887757 RW |
2599 | |
2600 | (define-public r-scone | |
2601 | (package | |
2602 | (name "r-scone") | |
26c72fff | 2603 | (version "1.8.0") |
f0887757 RW |
2604 | (source |
2605 | (origin | |
2606 | (method url-fetch) | |
2607 | (uri (bioconductor-uri "scone" version)) | |
2608 | (sha256 | |
2609 | (base32 | |
26c72fff | 2610 | "00cr0jp1ywxygf2pryw7mmcmn7cp1500fvifkbwgg2qxbkq5zqck")))) |
f0887757 RW |
2611 | (build-system r-build-system) |
2612 | (propagated-inputs | |
2613 | `(("r-aroma-light" ,r-aroma-light) | |
2614 | ("r-biocparallel" ,r-biocparallel) | |
2615 | ("r-boot" ,r-boot) | |
2616 | ("r-class" ,r-class) | |
2617 | ("r-cluster" ,r-cluster) | |
2618 | ("r-compositions" ,r-compositions) | |
2619 | ("r-diptest" ,r-diptest) | |
2620 | ("r-edger" ,r-edger) | |
2621 | ("r-fpc" ,r-fpc) | |
2622 | ("r-gplots" ,r-gplots) | |
2623 | ("r-hexbin" ,r-hexbin) | |
2624 | ("r-limma" ,r-limma) | |
2625 | ("r-matrixstats" ,r-matrixstats) | |
2626 | ("r-mixtools" ,r-mixtools) | |
2627 | ("r-rarpack" ,r-rarpack) | |
2628 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
2629 | ("r-rhdf5" ,r-rhdf5) | |
2630 | ("r-ruvseq" ,r-ruvseq) | |
2631 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2632 | (home-page "https://bioconductor.org/packages/scone") | |
2633 | (synopsis "Single cell overview of normalized expression data") | |
2634 | (description | |
2635 | "SCONE is an R package for comparing and ranking the performance of | |
2636 | different normalization schemes for single-cell RNA-seq and other | |
2637 | high-throughput analyses.") | |
2638 | (license license:artistic2.0))) | |
f9201d67 RW |
2639 | |
2640 | (define-public r-geoquery | |
2641 | (package | |
2642 | (name "r-geoquery") | |
2d443087 | 2643 | (version "2.52.0") |
f9201d67 RW |
2644 | (source |
2645 | (origin | |
2646 | (method url-fetch) | |
2647 | (uri (bioconductor-uri "GEOquery" version)) | |
2648 | (sha256 | |
2649 | (base32 | |
2d443087 | 2650 | "1r8x4jsl1mr9j7wyyqlj0zgwd80vkqhxxqrcgbb78ksryzq45jkr")))) |
f9201d67 RW |
2651 | (properties `((upstream-name . "GEOquery"))) |
2652 | (build-system r-build-system) | |
2653 | (propagated-inputs | |
2654 | `(("r-biobase" ,r-biobase) | |
2655 | ("r-dplyr" ,r-dplyr) | |
2656 | ("r-httr" ,r-httr) | |
2657 | ("r-limma" ,r-limma) | |
2658 | ("r-magrittr" ,r-magrittr) | |
2659 | ("r-readr" ,r-readr) | |
2660 | ("r-tidyr" ,r-tidyr) | |
2661 | ("r-xml2" ,r-xml2))) | |
2662 | (home-page "https://github.com/seandavi/GEOquery/") | |
2663 | (synopsis "Get data from NCBI Gene Expression Omnibus (GEO)") | |
2664 | (description | |
2665 | "The NCBI Gene Expression Omnibus (GEO) is a public repository of | |
2666 | microarray data. Given the rich and varied nature of this resource, it is | |
2667 | only natural to want to apply BioConductor tools to these data. GEOquery is | |
2668 | the bridge between GEO and BioConductor.") | |
2669 | (license license:gpl2))) | |
eed6ff03 RW |
2670 | |
2671 | (define-public r-illuminaio | |
2672 | (package | |
2673 | (name "r-illuminaio") | |
fadc6db8 | 2674 | (version "0.26.0") |
eed6ff03 RW |
2675 | (source |
2676 | (origin | |
2677 | (method url-fetch) | |
2678 | (uri (bioconductor-uri "illuminaio" version)) | |
2679 | (sha256 | |
2680 | (base32 | |
fadc6db8 | 2681 | "18plm8p40gfzfmqflxssrdj8az3xvmnmh9i9dafl3af3bxwv03l8")))) |
eed6ff03 RW |
2682 | (build-system r-build-system) |
2683 | (propagated-inputs | |
2684 | `(("r-base64" ,r-base64))) | |
2685 | (home-page "https://github.com/HenrikBengtsson/illuminaio/") | |
2686 | (synopsis "Parse Illumina microarray output files") | |
2687 | (description | |
2688 | "This package provides tools for parsing Illumina's microarray output | |
2689 | files, including IDAT.") | |
2690 | (license license:gpl2))) | |
f4eac096 RW |
2691 | |
2692 | (define-public r-siggenes | |
2693 | (package | |
2694 | (name "r-siggenes") | |
409f4dd6 | 2695 | (version "1.58.0") |
f4eac096 RW |
2696 | (source |
2697 | (origin | |
2698 | (method url-fetch) | |
2699 | (uri (bioconductor-uri "siggenes" version)) | |
2700 | (sha256 | |
2701 | (base32 | |
409f4dd6 | 2702 | "178jmmdxsv3rd71a9w5yrvg5aplak40hb42vna15g1d55c2yv1ib")))) |
f4eac096 RW |
2703 | (build-system r-build-system) |
2704 | (propagated-inputs | |
2705 | `(("r-biobase" ,r-biobase) | |
409f4dd6 RW |
2706 | ("r-multtest" ,r-multtest) |
2707 | ("r-scrime" ,r-scrime))) | |
f4eac096 RW |
2708 | (home-page "https://bioconductor.org/packages/siggenes/") |
2709 | (synopsis | |
2710 | "Multiple testing using SAM and Efron's empirical Bayes approaches") | |
2711 | (description | |
2712 | "This package provides tools for the identification of differentially | |
2713 | expressed genes and estimation of the @dfn{False Discovery Rate} (FDR) using | |
2714 | both the Significance Analysis of Microarrays (SAM) and the @dfn{Empirical | |
2715 | Bayes Analyses of Microarrays} (EBAM).") | |
2716 | (license license:lgpl2.0+))) | |
34a24f95 RW |
2717 | |
2718 | (define-public r-bumphunter | |
2719 | (package | |
2720 | (name "r-bumphunter") | |
693a9805 | 2721 | (version "1.26.0") |
34a24f95 RW |
2722 | (source |
2723 | (origin | |
2724 | (method url-fetch) | |
2725 | (uri (bioconductor-uri "bumphunter" version)) | |
2726 | (sha256 | |
2727 | (base32 | |
693a9805 | 2728 | "1dkyicwqdaahnxcxj6kmivkqb47yccx51lb1q0yar3xpw91vwlfx")))) |
34a24f95 RW |
2729 | (build-system r-build-system) |
2730 | (propagated-inputs | |
2731 | `(("r-annotationdbi" ,r-annotationdbi) | |
2732 | ("r-biocgenerics" ,r-biocgenerics) | |
2733 | ("r-dorng" ,r-dorng) | |
2734 | ("r-foreach" ,r-foreach) | |
2735 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2736 | ("r-genomicfeatures" ,r-genomicfeatures) | |
2737 | ("r-genomicranges" ,r-genomicranges) | |
2738 | ("r-iranges" ,r-iranges) | |
2739 | ("r-iterators" ,r-iterators) | |
2740 | ("r-limma" ,r-limma) | |
2741 | ("r-locfit" ,r-locfit) | |
2742 | ("r-matrixstats" ,r-matrixstats) | |
2743 | ("r-s4vectors" ,r-s4vectors))) | |
2744 | (home-page "https://github.com/ririzarr/bumphunter") | |
2745 | (synopsis "Find bumps in genomic data") | |
2746 | (description | |
2747 | "This package provides tools for finding bumps in genomic data in order | |
2748 | to identify differentially methylated regions in epigenetic epidemiology | |
2749 | studies.") | |
2750 | (license license:artistic2.0))) | |
0fbaf195 RW |
2751 | |
2752 | (define-public r-minfi | |
2753 | (package | |
2754 | (name "r-minfi") | |
8c0fae3c | 2755 | (version "1.30.0") |
0fbaf195 RW |
2756 | (source |
2757 | (origin | |
2758 | (method url-fetch) | |
2759 | (uri (bioconductor-uri "minfi" version)) | |
2760 | (sha256 | |
2761 | (base32 | |
8c0fae3c | 2762 | "0qir0zd0qa97fzm33v10nyrsjp8nmzhn7mn20dnlpsg7rwlf60pd")))) |
0fbaf195 RW |
2763 | (build-system r-build-system) |
2764 | (propagated-inputs | |
2765 | `(("r-beanplot" ,r-beanplot) | |
2766 | ("r-biobase" ,r-biobase) | |
2767 | ("r-biocgenerics" ,r-biocgenerics) | |
2768 | ("r-biocparallel" ,r-biocparallel) | |
2769 | ("r-biostrings" ,r-biostrings) | |
2770 | ("r-bumphunter" ,r-bumphunter) | |
2771 | ("r-data-table" ,r-data-table) | |
2772 | ("r-delayedarray" ,r-delayedarray) | |
2773 | ("r-delayedmatrixstats" ,r-delayedmatrixstats) | |
2774 | ("r-genefilter" ,r-genefilter) | |
2775 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2776 | ("r-genomicranges" ,r-genomicranges) | |
2777 | ("r-geoquery" ,r-geoquery) | |
2778 | ("r-hdf5array" ,r-hdf5array) | |
2779 | ("r-illuminaio" ,r-illuminaio) | |
2780 | ("r-iranges" ,r-iranges) | |
2781 | ("r-lattice" ,r-lattice) | |
2782 | ("r-limma" ,r-limma) | |
2783 | ("r-mass" ,r-mass) | |
2784 | ("r-mclust" ,r-mclust) | |
2785 | ("r-nlme" ,r-nlme) | |
2786 | ("r-nor1mix" ,r-nor1mix) | |
2787 | ("r-preprocesscore" ,r-preprocesscore) | |
2788 | ("r-quadprog" ,r-quadprog) | |
2789 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
2790 | ("r-reshape" ,r-reshape) | |
2791 | ("r-s4vectors" ,r-s4vectors) | |
2792 | ("r-siggenes" ,r-siggenes) | |
2793 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2794 | (home-page "https://github.com/hansenlab/minfi") | |
2795 | (synopsis "Analyze Illumina Infinium DNA methylation arrays") | |
2796 | (description | |
2797 | "This package provides tools to analyze and visualize Illumina Infinium | |
2798 | methylation arrays.") | |
2799 | (license license:artistic2.0))) | |
5ec5ba02 RW |
2800 | |
2801 | (define-public r-methylumi | |
2802 | (package | |
2803 | (name "r-methylumi") | |
2986b51f | 2804 | (version "2.30.0") |
5ec5ba02 RW |
2805 | (source |
2806 | (origin | |
2807 | (method url-fetch) | |
2808 | (uri (bioconductor-uri "methylumi" version)) | |
2809 | (sha256 | |
2810 | (base32 | |
2986b51f | 2811 | "13acn771ybi10v50x123bq5yqd62b8sr4gz77lpgaj192sxq9d9f")))) |
5ec5ba02 RW |
2812 | (build-system r-build-system) |
2813 | (propagated-inputs | |
2814 | `(("r-annotate" ,r-annotate) | |
2815 | ("r-annotationdbi" ,r-annotationdbi) | |
2816 | ("r-biobase" ,r-biobase) | |
2817 | ("r-biocgenerics" ,r-biocgenerics) | |
2818 | ("r-fdb-infiniummethylation-hg19" ,r-fdb-infiniummethylation-hg19) | |
2819 | ("r-genefilter" ,r-genefilter) | |
2820 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2821 | ("r-genomicranges" ,r-genomicranges) | |
2822 | ("r-ggplot2" ,r-ggplot2) | |
2823 | ("r-illuminaio" ,r-illuminaio) | |
2824 | ("r-iranges" ,r-iranges) | |
2825 | ("r-lattice" ,r-lattice) | |
2826 | ("r-matrixstats" ,r-matrixstats) | |
2827 | ("r-minfi" ,r-minfi) | |
2828 | ("r-reshape2" ,r-reshape2) | |
2829 | ("r-s4vectors" ,r-s4vectors) | |
2830 | ("r-scales" ,r-scales) | |
2831 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
2832 | (home-page "https://bioconductor.org/packages/methylumi") | |
2833 | (synopsis "Handle Illumina methylation data") | |
2834 | (description | |
2835 | "This package provides classes for holding and manipulating Illumina | |
2836 | methylation data. Based on eSet, it can contain MIAME information, sample | |
2837 | information, feature information, and multiple matrices of data. An | |
2838 | \"intelligent\" import function, methylumiR can read the Illumina text files | |
2839 | and create a MethyLumiSet. methylumIDAT can directly read raw IDAT files from | |
2840 | HumanMethylation27 and HumanMethylation450 microarrays. Normalization, | |
2841 | background correction, and quality control features for GoldenGate, Infinium, | |
2842 | and Infinium HD arrays are also included.") | |
2843 | (license license:gpl2))) | |
09605cb2 RW |
2844 | |
2845 | (define-public r-lumi | |
2846 | (package | |
2847 | (name "r-lumi") | |
5551b07c | 2848 | (version "2.36.0") |
09605cb2 RW |
2849 | (source |
2850 | (origin | |
2851 | (method url-fetch) | |
2852 | (uri (bioconductor-uri "lumi" version)) | |
2853 | (sha256 | |
2854 | (base32 | |
5551b07c | 2855 | "1rf6xmd2wnajjvnl50q63agakzjf4hrzn2chdsnhapi7fh7bcjba")))) |
09605cb2 RW |
2856 | (build-system r-build-system) |
2857 | (propagated-inputs | |
2858 | `(("r-affy" ,r-affy) | |
2859 | ("r-annotate" ,r-annotate) | |
2860 | ("r-annotationdbi" ,r-annotationdbi) | |
2861 | ("r-biobase" ,r-biobase) | |
2862 | ("r-dbi" ,r-dbi) | |
2863 | ("r-genomicfeatures" ,r-genomicfeatures) | |
2864 | ("r-genomicranges" ,r-genomicranges) | |
2865 | ("r-kernsmooth" ,r-kernsmooth) | |
2866 | ("r-lattice" ,r-lattice) | |
2867 | ("r-mass" ,r-mass) | |
2868 | ("r-methylumi" ,r-methylumi) | |
2869 | ("r-mgcv" ,r-mgcv) | |
2870 | ("r-nleqslv" ,r-nleqslv) | |
2871 | ("r-preprocesscore" ,r-preprocesscore) | |
2872 | ("r-rsqlite" ,r-rsqlite))) | |
2873 | (home-page "https://bioconductor.org/packages/lumi") | |
2874 | (synopsis "BeadArray-specific methods for Illumina methylation and expression microarrays") | |
2875 | (description | |
2876 | "The lumi package provides an integrated solution for the Illumina | |
2877 | microarray data analysis. It includes functions of Illumina | |
2878 | BeadStudio (GenomeStudio) data input, quality control, BeadArray-specific | |
2879 | variance stabilization, normalization and gene annotation at the probe level. | |
2880 | It also includes the functions of processing Illumina methylation microarrays, | |
2881 | especially Illumina Infinium methylation microarrays.") | |
2882 | (license license:lgpl2.0+))) | |
4291f36a RW |
2883 | |
2884 | (define-public r-linnorm | |
2885 | (package | |
2886 | (name "r-linnorm") | |
48c2a7eb | 2887 | (version "2.8.0") |
4291f36a RW |
2888 | (source |
2889 | (origin | |
2890 | (method url-fetch) | |
2891 | (uri (bioconductor-uri "Linnorm" version)) | |
2892 | (sha256 | |
2893 | (base32 | |
48c2a7eb | 2894 | "1rv3ljdwb71364qd2p8za3jpk08agvzwas6f63s5d8wjlapzm3i5")))) |
4291f36a RW |
2895 | (properties `((upstream-name . "Linnorm"))) |
2896 | (build-system r-build-system) | |
2897 | (propagated-inputs | |
2898 | `(("r-amap" ,r-amap) | |
2899 | ("r-apcluster" ,r-apcluster) | |
2900 | ("r-ellipse" ,r-ellipse) | |
2901 | ("r-fastcluster" ,r-fastcluster) | |
2902 | ("r-fpc" ,r-fpc) | |
2903 | ("r-ggdendro" ,r-ggdendro) | |
2904 | ("r-ggplot2" ,r-ggplot2) | |
2905 | ("r-gmodels" ,r-gmodels) | |
2906 | ("r-igraph" ,r-igraph) | |
2907 | ("r-limma" ,r-limma) | |
2908 | ("r-mass" ,r-mass) | |
2909 | ("r-mclust" ,r-mclust) | |
2910 | ("r-rcpp" ,r-rcpp) | |
2911 | ("r-rcpparmadillo" ,r-rcpparmadillo) | |
2912 | ("r-rtsne" ,r-rtsne) | |
2913 | ("r-statmod" ,r-statmod) | |
2914 | ("r-vegan" ,r-vegan) | |
2915 | ("r-zoo" ,r-zoo))) | |
2916 | (home-page "http://www.jjwanglab.org/Linnorm/") | |
2917 | (synopsis "Linear model and normality based transformation method") | |
2918 | (description | |
2919 | "Linnorm is an R package for the analysis of RNA-seq, scRNA-seq, ChIP-seq | |
2920 | count data or any large scale count data. It transforms such datasets for | |
2921 | parametric tests. In addition to the transformtion function (@code{Linnorm}), | |
2922 | the following pipelines are implemented: | |
2923 | ||
2924 | @enumerate | |
2925 | @item Library size/batch effect normalization (@code{Linnorm.Norm}) | |
2926 | @item Cell subpopluation analysis and visualization using t-SNE or PCA K-means | |
2927 | clustering or hierarchical clustering (@code{Linnorm.tSNE}, | |
2928 | @code{Linnorm.PCA}, @code{Linnorm.HClust}) | |
2929 | @item Differential expression analysis or differential peak detection using | |
2930 | limma (@code{Linnorm.limma}) | |
2931 | @item Highly variable gene discovery and visualization (@code{Linnorm.HVar}) | |
2932 | @item Gene correlation network analysis and visualization (@code{Linnorm.Cor}) | |
2933 | @item Stable gene selection for scRNA-seq data; for users without or who do | |
2934 | not want to rely on spike-in genes (@code{Linnorm.SGenes}) | |
2935 | @item Data imputation (@code{Linnorm.DataImput}). | |
2936 | @end enumerate | |
2937 | ||
2938 | Linnorm can work with raw count, CPM, RPKM, FPKM and TPM. Additionally, the | |
2939 | @code{RnaXSim} function is included for simulating RNA-seq data for the | |
2940 | evaluation of DEG analysis methods.") | |
2941 | (license license:expat))) | |
e4a17532 RW |
2942 | |
2943 | (define-public r-ioniser | |
2944 | (package | |
2945 | (name "r-ioniser") | |
2ee91179 | 2946 | (version "2.8.0") |
e4a17532 RW |
2947 | (source |
2948 | (origin | |
2949 | (method url-fetch) | |
2950 | (uri (bioconductor-uri "IONiseR" version)) | |
2951 | (sha256 | |
2952 | (base32 | |
2ee91179 | 2953 | "0kznyqqpm0zbah537p197z1cgrgh9w82whmq0aydfxzgs2vxdw2y")))) |
e4a17532 RW |
2954 | (properties `((upstream-name . "IONiseR"))) |
2955 | (build-system r-build-system) | |
2956 | (propagated-inputs | |
2957 | `(("r-biocgenerics" ,r-biocgenerics) | |
2958 | ("r-biocparallel" ,r-biocparallel) | |
2959 | ("r-biostrings" ,r-biostrings) | |
2960 | ("r-bit64" ,r-bit64) | |
2961 | ("r-dplyr" ,r-dplyr) | |
2962 | ("r-ggplot2" ,r-ggplot2) | |
2963 | ("r-magrittr" ,r-magrittr) | |
2964 | ("r-rhdf5" ,r-rhdf5) | |
2965 | ("r-shortread" ,r-shortread) | |
2966 | ("r-stringr" ,r-stringr) | |
2967 | ("r-tibble" ,r-tibble) | |
2968 | ("r-tidyr" ,r-tidyr) | |
2969 | ("r-xvector" ,r-xvector))) | |
2970 | (home-page "https://bioconductor.org/packages/IONiseR/") | |
2971 | (synopsis "Quality assessment tools for Oxford Nanopore MinION data") | |
2972 | (description | |
2973 | "IONiseR provides tools for the quality assessment of Oxford Nanopore | |
2974 | MinION data. It extracts summary statistics from a set of fast5 files and can | |
2975 | be used either before or after base calling. In addition to standard | |
2976 | summaries of the read-types produced, it provides a number of plots for | |
2977 | visualising metrics relative to experiment run time or spatially over the | |
2978 | surface of a flowcell.") | |
2979 | (license license:expat))) | |
80eb01c7 RW |
2980 | |
2981 | ;; This is a CRAN package, but it depends on packages from Bioconductor. | |
2982 | (define-public r-gkmsvm | |
2983 | (package | |
2984 | (name "r-gkmsvm") | |
2985 | (version "0.79.0") | |
2986 | (source | |
2987 | (origin | |
2988 | (method url-fetch) | |
2989 | (uri (cran-uri "gkmSVM" version)) | |
2990 | (sha256 | |
2991 | (base32 | |
2992 | "04dakbgfvfalz4rm4fvvybp506dn5fbj5g86ybfhrc6wywjllsz3")))) | |
2993 | (properties `((upstream-name . "gkmSVM"))) | |
2994 | (build-system r-build-system) | |
2995 | (propagated-inputs | |
2996 | `(("r-biocgenerics" ,r-biocgenerics) | |
2997 | ("r-biostrings" ,r-biostrings) | |
2998 | ("r-genomeinfodb" ,r-genomeinfodb) | |
2999 | ("r-genomicranges" ,r-genomicranges) | |
3000 | ("r-iranges" ,r-iranges) | |
3001 | ("r-kernlab" ,r-kernlab) | |
3002 | ("r-rcpp" ,r-rcpp) | |
3003 | ("r-rocr" ,r-rocr) | |
3004 | ("r-rtracklayer" ,r-rtracklayer) | |
3005 | ("r-s4vectors" ,r-s4vectors) | |
3006 | ("r-seqinr" ,r-seqinr))) | |
3007 | (home-page "https://cran.r-project.org/web/packages/gkmSVM") | |
3008 | (synopsis "Gapped-kmer support vector machine") | |
3009 | (description | |
3010 | "This R package provides tools for training gapped-kmer SVM classifiers | |
3011 | for DNA and protein sequences. This package supports several sequence | |
3012 | kernels, including: gkmSVM, kmer-SVM, mismatch kernel and wildcard kernel.") | |
3013 | (license license:gpl2+))) | |
8a5460b4 RW |
3014 | |
3015 | (define-public r-triform | |
3016 | (package | |
3017 | (name "r-triform") | |
bc083eca | 3018 | (version "1.26.0") |
8a5460b4 RW |
3019 | (source |
3020 | (origin | |
3021 | (method url-fetch) | |
3022 | (uri (bioconductor-uri "triform" version)) | |
3023 | (sha256 | |
3024 | (base32 | |
bc083eca | 3025 | "0bsxkn386kfx4gg19p6smy5fi3k7xdw89r5hvfsks8hsdpdz3hya")))) |
8a5460b4 RW |
3026 | (build-system r-build-system) |
3027 | (propagated-inputs | |
3028 | `(("r-biocgenerics" ,r-biocgenerics) | |
3029 | ("r-iranges" ,r-iranges) | |
3030 | ("r-yaml" ,r-yaml))) | |
3031 | (home-page "https://bioconductor.org/packages/triform/") | |
3032 | (synopsis "Find enriched regions in transcription factor ChIP-sequencing data") | |
3033 | (description | |
3034 | "The Triform algorithm uses model-free statistics to identify peak-like | |
3035 | distributions of TF ChIP sequencing reads, taking advantage of an improved | |
3036 | peak definition in combination with known profile characteristics.") | |
3037 | (license license:gpl2))) | |
c538bcdd RW |
3038 | |
3039 | (define-public r-varianttools | |
3040 | (package | |
3041 | (name "r-varianttools") | |
c2effded | 3042 | (version "1.26.0") |
c538bcdd RW |
3043 | (source |
3044 | (origin | |
3045 | (method url-fetch) | |
3046 | (uri (bioconductor-uri "VariantTools" version)) | |
3047 | (sha256 | |
3048 | (base32 | |
c2effded | 3049 | "0y37nziipwikg47x4jhhsx0dyv15rrih4a4z43jbzv4jgq4krzql")))) |
c538bcdd RW |
3050 | (properties `((upstream-name . "VariantTools"))) |
3051 | (build-system r-build-system) | |
3052 | (propagated-inputs | |
3053 | `(("r-biobase" ,r-biobase) | |
3054 | ("r-biocgenerics" ,r-biocgenerics) | |
3055 | ("r-biocparallel" ,r-biocparallel) | |
3056 | ("r-biostrings" ,r-biostrings) | |
3057 | ("r-bsgenome" ,r-bsgenome) | |
3058 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3059 | ("r-genomicfeatures" ,r-genomicfeatures) | |
3060 | ("r-genomicranges" ,r-genomicranges) | |
3061 | ("r-iranges" ,r-iranges) | |
3062 | ("r-matrix" ,r-matrix) | |
3063 | ("r-rsamtools" ,r-rsamtools) | |
3064 | ("r-rtracklayer" ,r-rtracklayer) | |
3065 | ("r-s4vectors" ,r-s4vectors) | |
3066 | ("r-variantannotation" ,r-variantannotation))) | |
3067 | (home-page "https://bioconductor.org/packages/VariantTools/") | |
3068 | (synopsis "Tools for exploratory analysis of variant calls") | |
3069 | (description | |
3070 | "Explore, diagnose, and compare variant calls using filters. The | |
3071 | VariantTools package supports a workflow for loading data, calling single | |
3072 | sample variants and tumor-specific somatic mutations or other sample-specific | |
3073 | variant types (e.g., RNA editing). Most of the functions operate on | |
3074 | alignments (BAM files) or datasets of called variants. The user is expected | |
3075 | to have already aligned the reads with a separate tool, e.g., GSNAP via | |
3076 | gmapR.") | |
3077 | (license license:artistic2.0))) | |
3e41919d RW |
3078 | |
3079 | (define-public r-heatplus | |
3080 | (package | |
3081 | (name "r-heatplus") | |
376d1fe7 | 3082 | (version "2.30.0") |
3e41919d RW |
3083 | (source |
3084 | (origin | |
3085 | (method url-fetch) | |
3086 | (uri (bioconductor-uri "Heatplus" version)) | |
3087 | (sha256 | |
3088 | (base32 | |
376d1fe7 | 3089 | "18b0zy12przp88sj1smvfdd39m17nhhnqzk656bs5pjls2ifmcm6")))) |
3e41919d RW |
3090 | (properties `((upstream-name . "Heatplus"))) |
3091 | (build-system r-build-system) | |
3092 | (propagated-inputs | |
3093 | `(("r-rcolorbrewer" ,r-rcolorbrewer))) | |
3094 | (home-page "https://github.com/alexploner/Heatplus") | |
3095 | (synopsis "Heatmaps with row and/or column covariates and colored clusters") | |
3096 | (description | |
3097 | "This package provides tools to display a rectangular heatmap (intensity | |
3098 | plot) of a data matrix. By default, both samples (columns) and features (row) | |
3099 | of the matrix are sorted according to a hierarchical clustering, and the | |
3100 | corresponding dendrogram is plotted. Optionally, panels with additional | |
3101 | information about samples and features can be added to the plot.") | |
3102 | (license license:gpl2+))) | |
c04f230e RW |
3103 | |
3104 | (define-public r-gosemsim | |
3105 | (package | |
3106 | (name "r-gosemsim") | |
24cf7bad | 3107 | (version "2.10.0") |
c04f230e RW |
3108 | (source |
3109 | (origin | |
3110 | (method url-fetch) | |
3111 | (uri (bioconductor-uri "GOSemSim" version)) | |
3112 | (sha256 | |
3113 | (base32 | |
24cf7bad | 3114 | "035jbm14rb1rjp2n00dp5bm88ad8a9afv4lvzpkv39nil98nzbdg")))) |
c04f230e RW |
3115 | (properties `((upstream-name . "GOSemSim"))) |
3116 | (build-system r-build-system) | |
3117 | (propagated-inputs | |
3118 | `(("r-annotationdbi" ,r-annotationdbi) | |
3119 | ("r-go-db" ,r-go-db) | |
3120 | ("r-rcpp" ,r-rcpp))) | |
3121 | (home-page "https://guangchuangyu.github.io/software/GOSemSim") | |
3122 | (synopsis "GO-terms semantic similarity measures") | |
3123 | (description | |
3124 | "The semantic comparisons of @dfn{Gene Ontology} (GO) annotations provide | |
3125 | quantitative ways to compute similarities between genes and gene groups, and | |
3126 | have became important basis for many bioinformatics analysis approaches. | |
3127 | GOSemSim is an R package for semantic similarity computation among GO terms, | |
3128 | sets of GO terms, gene products and gene clusters.") | |
3129 | (license license:artistic2.0))) | |
9d0f7942 RW |
3130 | |
3131 | (define-public r-anota | |
3132 | (package | |
3133 | (name "r-anota") | |
0a41b5db | 3134 | (version "1.32.0") |
9d0f7942 RW |
3135 | (source |
3136 | (origin | |
3137 | (method url-fetch) | |
3138 | (uri (bioconductor-uri "anota" version)) | |
3139 | (sha256 | |
3140 | (base32 | |
0a41b5db | 3141 | "0jchhyf9gqyj0k0fn5zp319griy32cckqpldq9x58z69l2ix2s2c")))) |
9d0f7942 RW |
3142 | (build-system r-build-system) |
3143 | (propagated-inputs | |
3144 | `(("r-multtest" ,r-multtest) | |
3145 | ("r-qvalue" ,r-qvalue))) | |
3146 | (home-page "https://bioconductor.org/packages/anota/") | |
3147 | (synopsis "Analysis of translational activity") | |
3148 | (description | |
3149 | "Genome wide studies of translational control is emerging as a tool to | |
0cea26bd | 3150 | study various biological conditions. The output from such analysis is both |
9d0f7942 RW |
3151 | the mRNA level (e.g. cytosolic mRNA level) and the levl of mRNA actively |
3152 | involved in translation (the actively translating mRNA level) for each mRNA. | |
3153 | The standard analysis of such data strives towards identifying differential | |
3154 | translational between two or more sample classes - i.e. differences in | |
3155 | actively translated mRNA levels that are independent of underlying differences | |
3156 | in cytosolic mRNA levels. This package allows for such analysis using partial | |
3157 | variances and the random variance model. As 10s of thousands of mRNAs are | |
4f664004 | 3158 | analyzed in parallel the library performs a number of tests to assure that |
9d0f7942 RW |
3159 | the data set is suitable for such analysis.") |
3160 | (license license:gpl3))) | |
a6d867fe RW |
3161 | |
3162 | (define-public r-sigpathway | |
3163 | (package | |
3164 | (name "r-sigpathway") | |
3e5ee6f6 | 3165 | (version "1.52.0") |
a6d867fe RW |
3166 | (source |
3167 | (origin | |
3168 | (method url-fetch) | |
3169 | (uri (bioconductor-uri "sigPathway" version)) | |
3170 | (sha256 | |
3171 | (base32 | |
3e5ee6f6 | 3172 | "1mc4lb78rcmpihzjiy4w738cbalw5zxms30z8kyy12s6vbxi6hx7")))) |
a6d867fe RW |
3173 | (properties `((upstream-name . "sigPathway"))) |
3174 | (build-system r-build-system) | |
3175 | (home-page "https://www.pnas.org/cgi/doi/10.1073/pnas.0506577102") | |
3176 | (synopsis "Pathway analysis") | |
3177 | (description | |
3178 | "This package is used to conduct pathway analysis by calculating the NT_k | |
3179 | and NE_k statistics in a statistical framework for determining whether a | |
3180 | specified group of genes for a pathway has a coordinated association with a | |
3181 | phenotype of interest.") | |
3182 | (license license:gpl2))) | |
af26c7ae RW |
3183 | |
3184 | (define-public r-fgsea | |
3185 | (package | |
3186 | (name "r-fgsea") | |
9b275285 | 3187 | (version "1.10.1") |
af26c7ae RW |
3188 | (source |
3189 | (origin | |
3190 | (method url-fetch) | |
3191 | (uri (bioconductor-uri "fgsea" version)) | |
3192 | (sha256 | |
3193 | (base32 | |
9b275285 | 3194 | "1k2f9hkp1mvc9fpqzhbf08jd0yg4xaa312v9vy37fxd9pyrwp5a6")))) |
af26c7ae RW |
3195 | (build-system r-build-system) |
3196 | (propagated-inputs | |
ebffd24c RW |
3197 | `(("r-bh" ,r-bh) |
3198 | ("r-biocparallel" ,r-biocparallel) | |
af26c7ae RW |
3199 | ("r-data-table" ,r-data-table) |
3200 | ("r-fastmatch" ,r-fastmatch) | |
3201 | ("r-ggplot2" ,r-ggplot2) | |
3202 | ("r-gridextra" ,r-gridextra) | |
3203 | ("r-matrix" ,r-matrix) | |
3204 | ("r-rcpp" ,r-rcpp))) | |
3205 | (home-page "https://github.com/ctlab/fgsea/") | |
3206 | (synopsis "Fast gene set enrichment analysis") | |
3207 | (description | |
3208 | "The package implements an algorithm for fast gene set enrichment | |
3209 | analysis. Using the fast algorithm allows to make more permutations and get | |
3210 | more fine grained p-values, which allows to use accurate stantard approaches | |
3211 | to multiple hypothesis correction.") | |
3212 | (license license:expat))) | |
305050b5 RW |
3213 | |
3214 | (define-public r-dose | |
3215 | (package | |
3216 | (name "r-dose") | |
aff3ecbf | 3217 | (version "3.10.2") |
305050b5 RW |
3218 | (source |
3219 | (origin | |
3220 | (method url-fetch) | |
3221 | (uri (bioconductor-uri "DOSE" version)) | |
3222 | (sha256 | |
3223 | (base32 | |
aff3ecbf | 3224 | "06jm1mnfd92s84f21562vsmj6jfkravfqf4lcxx2lk7s4ll66znj")))) |
305050b5 RW |
3225 | (properties `((upstream-name . "DOSE"))) |
3226 | (build-system r-build-system) | |
3227 | (propagated-inputs | |
3228 | `(("r-annotationdbi" ,r-annotationdbi) | |
3229 | ("r-biocparallel" ,r-biocparallel) | |
3230 | ("r-do-db" ,r-do-db) | |
3231 | ("r-fgsea" ,r-fgsea) | |
3232 | ("r-ggplot2" ,r-ggplot2) | |
3233 | ("r-gosemsim" ,r-gosemsim) | |
3234 | ("r-qvalue" ,r-qvalue) | |
3235 | ("r-reshape2" ,r-reshape2) | |
3236 | ("r-s4vectors" ,r-s4vectors))) | |
3237 | (home-page "https://guangchuangyu.github.io/software/DOSE/") | |
3238 | (synopsis "Disease ontology semantic and enrichment analysis") | |
3239 | (description | |
3240 | "This package implements five methods proposed by Resnik, Schlicker, | |
3241 | Jiang, Lin and Wang, respectively, for measuring semantic similarities among | |
3242 | @dfn{Disease ontology} (DO) terms and gene products. Enrichment analyses | |
3243 | including hypergeometric model and gene set enrichment analysis are also | |
3244 | implemented for discovering disease associations of high-throughput biological | |
3245 | data.") | |
3246 | (license license:artistic2.0))) | |
9c30cf65 RW |
3247 | |
3248 | (define-public r-enrichplot | |
3249 | (package | |
3250 | (name "r-enrichplot") | |
77d28d66 | 3251 | (version "1.4.0") |
9c30cf65 RW |
3252 | (source |
3253 | (origin | |
3254 | (method url-fetch) | |
3255 | (uri (bioconductor-uri "enrichplot" version)) | |
3256 | (sha256 | |
3257 | (base32 | |
77d28d66 | 3258 | "1i9psakvvdc6jn7k7zwpbdhwvf9r8s7649w05mwh1hy978x4rh6h")))) |
9c30cf65 RW |
3259 | (build-system r-build-system) |
3260 | (propagated-inputs | |
3261 | `(("r-annotationdbi" ,r-annotationdbi) | |
3262 | ("r-cowplot" ,r-cowplot) | |
3263 | ("r-dose" ,r-dose) | |
3264 | ("r-europepmc" ,r-europepmc) | |
3265 | ("r-ggplot2" ,r-ggplot2) | |
3266 | ("r-ggplotify" ,r-ggplotify) | |
3267 | ("r-ggraph" ,r-ggraph) | |
3268 | ("r-ggridges" ,r-ggridges) | |
3269 | ("r-gosemsim" ,r-gosemsim) | |
3270 | ("r-gridextra" ,r-gridextra) | |
3271 | ("r-igraph" ,r-igraph) | |
3272 | ("r-purrr" ,r-purrr) | |
3273 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
3274 | ("r-reshape2" ,r-reshape2) | |
3275 | ("r-upsetr" ,r-upsetr))) | |
3276 | (home-page "https://github.com/GuangchuangYu/enrichplot") | |
3277 | (synopsis "Visualization of functional enrichment result") | |
3278 | (description | |
3279 | "The enrichplot package implements several visualization methods for | |
3280 | interpreting functional enrichment results obtained from ORA or GSEA analyses. | |
3281 | All the visualization methods are developed based on ggplot2 graphics.") | |
3282 | (license license:artistic2.0))) | |
f8295ee6 RW |
3283 | |
3284 | (define-public r-clusterprofiler | |
3285 | (package | |
3286 | (name "r-clusterprofiler") | |
1a3e33be | 3287 | (version "3.12.0") |
f8295ee6 RW |
3288 | (source |
3289 | (origin | |
3290 | (method url-fetch) | |
3291 | (uri (bioconductor-uri "clusterProfiler" version)) | |
3292 | (sha256 | |
3293 | (base32 | |
1a3e33be | 3294 | "1jw8h6nlcgd86qhqlcgi3icylb7amcqimlvzg29gay3bf3grwfhq")))) |
f8295ee6 RW |
3295 | (properties |
3296 | `((upstream-name . "clusterProfiler"))) | |
3297 | (build-system r-build-system) | |
3298 | (propagated-inputs | |
3299 | `(("r-annotationdbi" ,r-annotationdbi) | |
3300 | ("r-dose" ,r-dose) | |
3301 | ("r-enrichplot" ,r-enrichplot) | |
3302 | ("r-ggplot2" ,r-ggplot2) | |
3303 | ("r-go-db" ,r-go-db) | |
3304 | ("r-gosemsim" ,r-gosemsim) | |
3305 | ("r-magrittr" ,r-magrittr) | |
3306 | ("r-plyr" ,r-plyr) | |
3307 | ("r-qvalue" ,r-qvalue) | |
3308 | ("r-rvcheck" ,r-rvcheck) | |
3309 | ("r-tidyr" ,r-tidyr))) | |
3310 | (home-page "https://guangchuangyu.github.io/software/clusterProfiler/") | |
3311 | (synopsis "Analysis and visualization of functional profiles for gene clusters") | |
3312 | (description | |
3313 | "This package implements methods to analyze and visualize functional | |
3314 | profiles (GO and KEGG) of gene and gene clusters.") | |
3315 | (license license:artistic2.0))) | |
ce77562a RW |
3316 | |
3317 | (define-public r-mlinterfaces | |
3318 | (package | |
3319 | (name "r-mlinterfaces") | |
8265a111 | 3320 | (version "1.64.0") |
ce77562a RW |
3321 | (source |
3322 | (origin | |
3323 | (method url-fetch) | |
3324 | (uri (bioconductor-uri "MLInterfaces" version)) | |
3325 | (sha256 | |
3326 | (base32 | |
8265a111 | 3327 | "0zqvxmvbkig3cc4r5k405s53d7y5ccvrf8kf5j6v8s1kkrklai4j")))) |
ce77562a RW |
3328 | (properties `((upstream-name . "MLInterfaces"))) |
3329 | (build-system r-build-system) | |
3330 | (propagated-inputs | |
3331 | `(("r-annotate" ,r-annotate) | |
3332 | ("r-biobase" ,r-biobase) | |
3333 | ("r-biocgenerics" ,r-biocgenerics) | |
3334 | ("r-cluster" ,r-cluster) | |
3335 | ("r-fpc" ,r-fpc) | |
3336 | ("r-gbm" ,r-gbm) | |
3337 | ("r-gdata" ,r-gdata) | |
3338 | ("r-genefilter" ,r-genefilter) | |
3339 | ("r-ggvis" ,r-ggvis) | |
3340 | ("r-hwriter" ,r-hwriter) | |
3341 | ("r-mass" ,r-mass) | |
3342 | ("r-mlbench" ,r-mlbench) | |
3343 | ("r-pls" ,r-pls) | |
3344 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
3345 | ("r-rda" ,r-rda) | |
3346 | ("r-rpart" ,r-rpart) | |
3347 | ("r-sfsmisc" ,r-sfsmisc) | |
3348 | ("r-shiny" ,r-shiny) | |
3349 | ("r-threejs" ,r-threejs))) | |
3350 | (home-page "https://bioconductor.org/packages/MLInterfaces/") | |
3351 | (synopsis "Interfaces to R machine learning procedures") | |
3352 | (description | |
3353 | "This package provides uniform interfaces to machine learning code for | |
3354 | data in R and Bioconductor containers.") | |
3355 | ;; Any version of the LGPL. | |
3356 | (license license:lgpl2.1+))) | |
a793e88c RW |
3357 | |
3358 | (define-public r-annaffy | |
3359 | (package | |
3360 | (name "r-annaffy") | |
8bef9df4 | 3361 | (version "1.56.0") |
a793e88c RW |
3362 | (source |
3363 | (origin | |
3364 | (method url-fetch) | |
3365 | (uri (bioconductor-uri "annaffy" version)) | |
3366 | (sha256 | |
3367 | (base32 | |
8bef9df4 | 3368 | "0sz96lcw0xc4bw1h3x0j40yh5ragmybsq6zwd0adlwzkhvriqjn9")))) |
a793e88c RW |
3369 | (build-system r-build-system) |
3370 | (arguments | |
3371 | `(#:phases | |
3372 | (modify-phases %standard-phases | |
3373 | (add-after 'unpack 'remove-reference-to-non-free-data | |
3374 | (lambda _ | |
3375 | (substitute* "DESCRIPTION" | |
3376 | ((", KEGG.db") "")) | |
3377 | #t))))) | |
3378 | (propagated-inputs | |
3379 | `(("r-annotationdbi" ,r-annotationdbi) | |
3380 | ("r-biobase" ,r-biobase) | |
3381 | ("r-dbi" ,r-dbi) | |
3382 | ("r-go-db" ,r-go-db))) | |
3383 | (home-page "https://bioconductor.org/packages/annaffy/") | |
3384 | (synopsis "Annotation tools for Affymetrix biological metadata") | |
3385 | (description | |
3386 | "This package provides functions for handling data from Bioconductor | |
3387 | Affymetrix annotation data packages. It produces compact HTML and text | |
3388 | reports including experimental data and URL links to many online databases. | |
3389 | It allows searching of biological metadata using various criteria.") | |
3390 | ;; Any version of the LGPL according to the DESCRIPTION file. A copy of | |
3391 | ;; the LGPL 2.1 is included. | |
3392 | (license license:lgpl2.1+))) | |
0ec0a5ec RW |
3393 | |
3394 | (define-public r-a4core | |
3395 | (package | |
3396 | (name "r-a4core") | |
b077e3db | 3397 | (version "1.32.0") |
0ec0a5ec RW |
3398 | (source |
3399 | (origin | |
3400 | (method url-fetch) | |
3401 | (uri (bioconductor-uri "a4Core" version)) | |
3402 | (sha256 | |
3403 | (base32 | |
b077e3db | 3404 | "1cr0d1w81iygil3pygqzigfb1a0hc248qd9vqvs0n537cxrxq7i7")))) |
0ec0a5ec RW |
3405 | (properties `((upstream-name . "a4Core"))) |
3406 | (build-system r-build-system) | |
3407 | (propagated-inputs | |
3408 | `(("r-biobase" ,r-biobase) | |
3409 | ("r-glmnet" ,r-glmnet))) | |
3410 | (home-page "https://bioconductor.org/packages/a4Core") | |
3411 | (synopsis "Automated Affymetrix array analysis core package") | |
3412 | (description | |
3413 | "This is the core package for the automated analysis of Affymetrix | |
3414 | arrays.") | |
3415 | (license license:gpl3))) | |
9ae37581 RW |
3416 | |
3417 | (define-public r-a4classif | |
3418 | (package | |
3419 | (name "r-a4classif") | |
82de77da | 3420 | (version "1.32.0") |
9ae37581 RW |
3421 | (source |
3422 | (origin | |
3423 | (method url-fetch) | |
3424 | (uri (bioconductor-uri "a4Classif" version)) | |
3425 | (sha256 | |
3426 | (base32 | |
82de77da | 3427 | "1jif0w3hx020zzwkaza1a26mf34343y7a3v80ic93in6n53yjhj0")))) |
9ae37581 RW |
3428 | (properties `((upstream-name . "a4Classif"))) |
3429 | (build-system r-build-system) | |
3430 | (propagated-inputs | |
3431 | `(("r-a4core" ,r-a4core) | |
3432 | ("r-a4preproc" ,r-a4preproc) | |
3433 | ("r-glmnet" ,r-glmnet) | |
3434 | ("r-mlinterfaces" ,r-mlinterfaces) | |
3435 | ("r-pamr" ,r-pamr) | |
3436 | ("r-rocr" ,r-rocr) | |
3437 | ("r-varselrf" ,r-varselrf))) | |
3438 | (home-page "https://bioconductor.org/packages/a4Classif/") | |
3439 | (synopsis "Automated Affymetrix array analysis classification package") | |
3440 | (description | |
3441 | "This is the classification package for the automated analysis of | |
3442 | Affymetrix arrays.") | |
3443 | (license license:gpl3))) | |
b8d13e2c RW |
3444 | |
3445 | (define-public r-a4preproc | |
3446 | (package | |
3447 | (name "r-a4preproc") | |
0b609162 | 3448 | (version "1.32.0") |
b8d13e2c RW |
3449 | (source |
3450 | (origin | |
3451 | (method url-fetch) | |
3452 | (uri (bioconductor-uri "a4Preproc" version)) | |
3453 | (sha256 | |
3454 | (base32 | |
0b609162 | 3455 | "13sj4zriq1mian2xcjwkbmmpdjh3h6dgjslar2hc8nmd34cb9xjr")))) |
b8d13e2c RW |
3456 | (properties `((upstream-name . "a4Preproc"))) |
3457 | (build-system r-build-system) | |
3458 | (propagated-inputs | |
3459 | `(("r-annotationdbi" ,r-annotationdbi))) | |
3460 | (home-page "https://bioconductor.org/packages/a4Preproc/") | |
3461 | (synopsis "Automated Affymetrix array analysis preprocessing package") | |
3462 | (description | |
3463 | "This is a package for the automated analysis of Affymetrix arrays. It | |
3464 | is used for preprocessing the arrays.") | |
3465 | (license license:gpl3))) | |
8e15f861 RW |
3466 | |
3467 | (define-public r-a4reporting | |
3468 | (package | |
3469 | (name "r-a4reporting") | |
e5a36543 | 3470 | (version "1.32.0") |
8e15f861 RW |
3471 | (source |
3472 | (origin | |
3473 | (method url-fetch) | |
3474 | (uri (bioconductor-uri "a4Reporting" version)) | |
3475 | (sha256 | |
3476 | (base32 | |
e5a36543 | 3477 | "1lail2iw8jmvfdq9brv7i41k6vmbhx2kp21jxq2cj1zva5rcqssj")))) |
8e15f861 RW |
3478 | (properties `((upstream-name . "a4Reporting"))) |
3479 | (build-system r-build-system) | |
3480 | (propagated-inputs | |
3481 | `(("r-annaffy" ,r-annaffy) | |
3482 | ("r-xtable" ,r-xtable))) | |
3483 | (home-page "https://bioconductor.org/packages/a4Reporting/") | |
3484 | (synopsis "Automated Affymetrix array analysis reporting package") | |
3485 | (description | |
3486 | "This is a package for the automated analysis of Affymetrix arrays. It | |
3487 | provides reporting features.") | |
3488 | (license license:gpl3))) | |
dbfe3375 RW |
3489 | |
3490 | (define-public r-a4base | |
3491 | (package | |
3492 | (name "r-a4base") | |
ae1730ae | 3493 | (version "1.32.0") |
dbfe3375 RW |
3494 | (source |
3495 | (origin | |
3496 | (method url-fetch) | |
3497 | (uri (bioconductor-uri "a4Base" version)) | |
3498 | (sha256 | |
3499 | (base32 | |
ae1730ae | 3500 | "0yd8gkg3dlkijnms88bxkqsghhc9i32pgd9yaq6hzr67wk879wa1")))) |
dbfe3375 RW |
3501 | (properties `((upstream-name . "a4Base"))) |
3502 | (build-system r-build-system) | |
3503 | (propagated-inputs | |
3504 | `(("r-a4core" ,r-a4core) | |
3505 | ("r-a4preproc" ,r-a4preproc) | |
3506 | ("r-annaffy" ,r-annaffy) | |
3507 | ("r-annotationdbi" ,r-annotationdbi) | |
3508 | ("r-biobase" ,r-biobase) | |
3509 | ("r-genefilter" ,r-genefilter) | |
3510 | ("r-glmnet" ,r-glmnet) | |
3511 | ("r-gplots" ,r-gplots) | |
3512 | ("r-limma" ,r-limma) | |
3513 | ("r-mpm" ,r-mpm) | |
3514 | ("r-multtest" ,r-multtest))) | |
3515 | (home-page "https://bioconductor.org/packages/a4Base/") | |
3516 | (synopsis "Automated Affymetrix array analysis base package") | |
3517 | (description | |
3518 | "This package provides basic features for the automated analysis of | |
3519 | Affymetrix arrays.") | |
3520 | (license license:gpl3))) | |
84ad024e RW |
3521 | |
3522 | (define-public r-a4 | |
3523 | (package | |
3524 | (name "r-a4") | |
1aadddea | 3525 | (version "1.32.0") |
84ad024e RW |
3526 | (source |
3527 | (origin | |
3528 | (method url-fetch) | |
3529 | (uri (bioconductor-uri "a4" version)) | |
3530 | (sha256 | |
3531 | (base32 | |
1aadddea | 3532 | "08146qzsr6mjblmh08g83063nnyrfl35z6p65v71isprkydgxyhy")))) |
84ad024e RW |
3533 | (build-system r-build-system) |
3534 | (propagated-inputs | |
3535 | `(("r-a4base" ,r-a4base) | |
3536 | ("r-a4classif" ,r-a4classif) | |
3537 | ("r-a4core" ,r-a4core) | |
3538 | ("r-a4preproc" ,r-a4preproc) | |
3539 | ("r-a4reporting" ,r-a4reporting))) | |
3540 | (home-page "https://bioconductor.org/packages/a4/") | |
3541 | (synopsis "Automated Affymetrix array analysis umbrella package") | |
3542 | (description | |
3543 | "This package provides a software suite for the automated analysis of | |
3544 | Affymetrix arrays.") | |
3545 | (license license:gpl3))) | |
59d331f1 RW |
3546 | |
3547 | (define-public r-abseqr | |
3548 | (package | |
3549 | (name "r-abseqr") | |
b7ddf0f0 | 3550 | (version "1.2.0") |
59d331f1 RW |
3551 | (source |
3552 | (origin | |
3553 | (method url-fetch) | |
3554 | (uri (bioconductor-uri "abseqR" version)) | |
3555 | (sha256 | |
3556 | (base32 | |
b7ddf0f0 | 3557 | "0cbjm7cxjfrkwqhcrrh93w0zf3skmi2p9hyx7acg0ym5fz0ic51r")))) |
59d331f1 RW |
3558 | (properties `((upstream-name . "abseqR"))) |
3559 | (build-system r-build-system) | |
3560 | (inputs | |
3561 | `(("pandoc" ,ghc-pandoc))) | |
3562 | (propagated-inputs | |
3563 | `(("r-biocparallel" ,r-biocparallel) | |
3564 | ("r-biocstyle" ,r-biocstyle) | |
3565 | ("r-circlize" ,r-circlize) | |
3566 | ("r-flexdashboard" ,r-flexdashboard) | |
3567 | ("r-ggcorrplot" ,r-ggcorrplot) | |
3568 | ("r-ggdendro" ,r-ggdendro) | |
3569 | ("r-ggplot2" ,r-ggplot2) | |
3570 | ("r-gridextra" ,r-gridextra) | |
3571 | ("r-knitr" ,r-knitr) | |
3572 | ("r-plotly" ,r-plotly) | |
3573 | ("r-plyr" ,r-plyr) | |
3574 | ("r-png" ,r-png) | |
3575 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
3576 | ("r-reshape2" ,r-reshape2) | |
3577 | ("r-rmarkdown" ,r-rmarkdown) | |
3578 | ("r-stringr" ,r-stringr) | |
3579 | ("r-vegan" ,r-vegan) | |
3580 | ("r-venndiagram" ,r-venndiagram))) | |
3581 | (home-page "https://github.com/malhamdoosh/abseqR") | |
3582 | (synopsis "Reporting and data analysis for Rep-Seq datasets of antibody libraries") | |
3583 | (description | |
3584 | "AbSeq is a comprehensive bioinformatic pipeline for the analysis of | |
3585 | sequencing datasets generated from antibody libraries and abseqR is one of its | |
3586 | packages. AbseqR empowers the users of abseqPy with plotting and reporting | |
3587 | capabilities and allows them to generate interactive HTML reports for the | |
3588 | convenience of viewing and sharing with other researchers. Additionally, | |
3589 | abseqR extends abseqPy to compare multiple repertoire analyses and perform | |
3590 | further downstream analysis on its output.") | |
3591 | (license license:gpl3))) | |
41aab7d1 RW |
3592 | |
3593 | (define-public r-bacon | |
3594 | (package | |
3595 | (name "r-bacon") | |
e33c25ff | 3596 | (version "1.12.0") |
41aab7d1 RW |
3597 | (source |
3598 | (origin | |
3599 | (method url-fetch) | |
3600 | (uri (bioconductor-uri "bacon" version)) | |
3601 | (sha256 | |
3602 | (base32 | |
e33c25ff | 3603 | "1p6h348kwbsan6dwviclwxx02jcdmf580g5f95w2sgn4jnfv7q1q")))) |
41aab7d1 RW |
3604 | (build-system r-build-system) |
3605 | (propagated-inputs | |
3606 | `(("r-biocparallel" ,r-biocparallel) | |
3607 | ("r-ellipse" ,r-ellipse) | |
3608 | ("r-ggplot2" ,r-ggplot2))) | |
3609 | (home-page "https://bioconductor.org/packages/bacon/") | |
3610 | (synopsis "Controlling bias and inflation in association studies") | |
3611 | (description | |
3612 | "Bacon can be used to remove inflation and bias often observed in | |
3613 | epigenome- and transcriptome-wide association studies. To this end bacon | |
3614 | constructs an empirical null distribution using a Gibbs Sampling algorithm by | |
3615 | fitting a three-component normal mixture on z-scores.") | |
3616 | (license license:gpl2+))) | |
051e8e1a RW |
3617 | |
3618 | (define-public r-rgadem | |
3619 | (package | |
3620 | (name "r-rgadem") | |
93f8a009 | 3621 | (version "2.32.0") |
051e8e1a RW |
3622 | (source |
3623 | (origin | |
3624 | (method url-fetch) | |
3625 | (uri (bioconductor-uri "rGADEM" version)) | |
3626 | (sha256 | |
3627 | (base32 | |
93f8a009 | 3628 | "1zf8ayllf1i79wc39vyln2hii1bgg88sw6h1hngkqx4phyvl9q18")))) |
051e8e1a RW |
3629 | (properties `((upstream-name . "rGADEM"))) |
3630 | (build-system r-build-system) | |
3631 | (propagated-inputs | |
3632 | `(("r-biostrings" ,r-biostrings) | |
3633 | ("r-bsgenome" ,r-bsgenome) | |
3634 | ("r-iranges" ,r-iranges) | |
3635 | ("r-seqlogo" ,r-seqlogo))) | |
3636 | (home-page "https://bioconductor.org/packages/rGADEM/") | |
3637 | (synopsis "De novo sequence motif discovery") | |
3638 | (description | |
3639 | "rGADEM is an efficient de novo motif discovery tool for large-scale | |
3640 | genomic sequence data.") | |
3641 | (license license:artistic2.0))) | |
229f97c3 RW |
3642 | |
3643 | (define-public r-motiv | |
3644 | (package | |
3645 | (name "r-motiv") | |
f7a495b1 | 3646 | (version "1.40.0") |
229f97c3 RW |
3647 | (source |
3648 | (origin | |
3649 | (method url-fetch) | |
3650 | (uri (bioconductor-uri "MotIV" version)) | |
3651 | (sha256 | |
3652 | (base32 | |
f7a495b1 | 3653 | "088z3vyx5h2c4ll4sway01cd4h0x2ayhbv55f6l2kss71v6k6byf")))) |
229f97c3 RW |
3654 | (properties `((upstream-name . "MotIV"))) |
3655 | (build-system r-build-system) | |
3656 | (inputs | |
3657 | `(("gsl" ,gsl))) | |
3658 | (propagated-inputs | |
3659 | `(("r-biocgenerics" ,r-biocgenerics) | |
3660 | ("r-biostrings" ,r-biostrings) | |
3661 | ("r-iranges" ,r-iranges) | |
3662 | ("r-lattice" ,r-lattice) | |
3663 | ("r-rgadem" ,r-rgadem) | |
3664 | ("r-s4vectors" ,r-s4vectors))) | |
3665 | (home-page "https://bioconductor.org/packages/MotIV/") | |
3666 | (synopsis "Motif identification and validation") | |
3667 | (description | |
3668 | "This package is used for the identification and validation of sequence | |
3669 | motifs. It makes use of STAMP for comparing a set of motifs to a given | |
3670 | database (e.g. JASPAR). It can also be used to visualize motifs, motif | |
3671 | distributions, modules and filter motifs.") | |
3672 | (license license:gpl2))) | |
2a72ef56 RW |
3673 | |
3674 | (define-public r-motifstack | |
3675 | (package | |
3676 | (name "r-motifstack") | |
aa0ebfd2 | 3677 | (version "1.28.0") |
2a72ef56 RW |
3678 | (source |
3679 | (origin | |
3680 | (method url-fetch) | |
3681 | (uri (bioconductor-uri "motifStack" version)) | |
3682 | (sha256 | |
3683 | (base32 | |
aa0ebfd2 | 3684 | "0qbv5pvn1g9xfn221vqjmp9vfxpkda1wxkn0kyn2nqyb80d4jf9f")))) |
2a72ef56 RW |
3685 | (properties `((upstream-name . "motifStack"))) |
3686 | (build-system r-build-system) | |
3687 | (propagated-inputs | |
3688 | `(("r-ade4" ,r-ade4) | |
3689 | ("r-biostrings" ,r-biostrings) | |
aa0ebfd2 | 3690 | ("r-grimport2" ,r-grimport2) |
2a72ef56 RW |
3691 | ("r-htmlwidgets" ,r-htmlwidgets) |
3692 | ("r-motiv" ,r-motiv) | |
3693 | ("r-scales" ,r-scales) | |
3694 | ("r-xml" ,r-xml))) | |
3695 | (home-page "https://bioconductor.org/packages/motifStack/") | |
3696 | (synopsis "Plot stacked logos for DNA, RNA and amino acid sequences") | |
3697 | (description | |
3698 | "The motifStack package is designed for graphic representation of | |
3699 | multiple motifs with different similarity scores. It works with both DNA/RNA | |
3700 | sequence motifs and amino acid sequence motifs. In addition, it provides the | |
3701 | flexibility for users to customize the graphic parameters such as the font | |
3702 | type and symbol colors.") | |
3703 | (license license:gpl2+))) | |
e5bff307 RW |
3704 | |
3705 | (define-public r-genomicscores | |
3706 | (package | |
3707 | (name "r-genomicscores") | |
3c944fda | 3708 | (version "1.8.1") |
e5bff307 RW |
3709 | (source |
3710 | (origin | |
3711 | (method url-fetch) | |
3712 | (uri (bioconductor-uri "GenomicScores" version)) | |
3713 | (sha256 | |
3714 | (base32 | |
3c944fda | 3715 | "0xgv5h6hwr4p2p05z8vzhivy97gfirm4rj1ihb5c8fhgc5vp85dy")))) |
e5bff307 RW |
3716 | (properties `((upstream-name . "GenomicScores"))) |
3717 | (build-system r-build-system) | |
3718 | (propagated-inputs | |
3719 | `(("r-annotationhub" ,r-annotationhub) | |
3720 | ("r-biobase" ,r-biobase) | |
3721 | ("r-biocgenerics" ,r-biocgenerics) | |
3722 | ("r-biostrings" ,r-biostrings) | |
3723 | ("r-bsgenome" ,r-bsgenome) | |
3724 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3725 | ("r-genomicranges" ,r-genomicranges) | |
3726 | ("r-iranges" ,r-iranges) | |
3727 | ("r-s4vectors" ,r-s4vectors) | |
3728 | ("r-xml" ,r-xml))) | |
3729 | (home-page "https://github.com/rcastelo/GenomicScores/") | |
3730 | (synopsis "Work with genome-wide position-specific scores") | |
3731 | (description | |
3732 | "This package provides infrastructure to store and access genome-wide | |
3733 | position-specific scores within R and Bioconductor.") | |
3734 | (license license:artistic2.0))) | |
32e0f906 RW |
3735 | |
3736 | (define-public r-atacseqqc | |
3737 | (package | |
3738 | (name "r-atacseqqc") | |
fbe5a087 | 3739 | (version "1.8.5") |
32e0f906 RW |
3740 | (source |
3741 | (origin | |
3742 | (method url-fetch) | |
3743 | (uri (bioconductor-uri "ATACseqQC" version)) | |
3744 | (sha256 | |
3745 | (base32 | |
fbe5a087 | 3746 | "1i8f0vs0z4jbc2yvj1diay7jhcmb1a82zv96xllk771f25nvmmxp")))) |
32e0f906 RW |
3747 | (properties `((upstream-name . "ATACseqQC"))) |
3748 | (build-system r-build-system) | |
3749 | (propagated-inputs | |
3750 | `(("r-biocgenerics" ,r-biocgenerics) | |
3751 | ("r-biostrings" ,r-biostrings) | |
3752 | ("r-bsgenome" ,r-bsgenome) | |
3753 | ("r-chippeakanno" ,r-chippeakanno) | |
bcc233c1 | 3754 | ("r-edger" ,r-edger) |
32e0f906 RW |
3755 | ("r-genomeinfodb" ,r-genomeinfodb) |
3756 | ("r-genomicalignments" ,r-genomicalignments) | |
3757 | ("r-genomicranges" ,r-genomicranges) | |
3758 | ("r-genomicscores" ,r-genomicscores) | |
3759 | ("r-iranges" ,r-iranges) | |
3760 | ("r-kernsmooth" ,r-kernsmooth) | |
3761 | ("r-limma" ,r-limma) | |
3762 | ("r-motifstack" ,r-motifstack) | |
3763 | ("r-preseqr" ,r-preseqr) | |
3764 | ("r-randomforest" ,r-randomforest) | |
3765 | ("r-rsamtools" ,r-rsamtools) | |
3766 | ("r-rtracklayer" ,r-rtracklayer) | |
3767 | ("r-s4vectors" ,r-s4vectors))) | |
3768 | (home-page "https://bioconductor.org/packages/ATACseqQC/") | |
3769 | (synopsis "ATAC-seq quality control") | |
3770 | (description | |
3771 | "ATAC-seq, an assay for Transposase-Accessible Chromatin using | |
3772 | sequencing, is a rapid and sensitive method for chromatin accessibility | |
3773 | analysis. It was developed as an alternative method to MNase-seq, FAIRE-seq | |
3774 | and DNAse-seq. The ATACseqQC package was developed to help users to quickly | |
3775 | assess whether their ATAC-seq experiment is successful. It includes | |
3776 | diagnostic plots of fragment size distribution, proportion of mitochondria | |
3777 | reads, nucleosome positioning pattern, and CTCF or other Transcript Factor | |
3778 | footprints.") | |
3779 | (license license:gpl2+))) | |
3972cfce RW |
3780 | |
3781 | (define-public r-gofuncr | |
3782 | (package | |
3783 | (name "r-gofuncr") | |
bab06a6f | 3784 | (version "1.4.0") |
3972cfce RW |
3785 | (source |
3786 | (origin | |
3787 | (method url-fetch) | |
3788 | (uri (bioconductor-uri "GOfuncR" version)) | |
3789 | (sha256 | |
3790 | (base32 | |
bab06a6f | 3791 | "1znnkh96yyv6rkbjxx2942nixw4ixdll1f72v92wzsxdcbwkgqdm")))) |
3972cfce RW |
3792 | (properties `((upstream-name . "GOfuncR"))) |
3793 | (build-system r-build-system) | |
3794 | (propagated-inputs | |
3795 | `(("r-annotationdbi" ,r-annotationdbi) | |
3796 | ("r-genomicranges" ,r-genomicranges) | |
3797 | ("r-gtools" ,r-gtools) | |
3798 | ("r-iranges" ,r-iranges) | |
3799 | ("r-mapplots" ,r-mapplots) | |
3800 | ("r-rcpp" ,r-rcpp) | |
3801 | ("r-vioplot" ,r-vioplot))) | |
3802 | (home-page "https://bioconductor.org/packages/GOfuncR/") | |
3803 | (synopsis "Gene ontology enrichment using FUNC") | |
3804 | (description | |
3805 | "GOfuncR performs a gene ontology enrichment analysis based on the | |
3806 | ontology enrichment software FUNC. GO-annotations are obtained from | |
3807 | OrganismDb or OrgDb packages (@code{Homo.sapiens} by default); the GO-graph is | |
3808 | included in the package and updated regularly. GOfuncR provides the standard | |
3809 | candidate vs background enrichment analysis using the hypergeometric test, as | |
3810 | well as three additional tests: | |
3811 | ||
3812 | @enumerate | |
3813 | @item the Wilcoxon rank-sum test that is used when genes are ranked, | |
3814 | @item a binomial test that is used when genes are associated with two counts, | |
3815 | and | |
3816 | @item a Chi-square or Fisher's exact test that is used in cases when genes are | |
3817 | associated with four counts. | |
3818 | @end enumerate | |
3819 | ||
3820 | To correct for multiple testing and interdependency of the tests, family-wise | |
3821 | error rates are computed based on random permutations of the gene-associated | |
3822 | variables. GOfuncR also provides tools for exploring the ontology graph and | |
3823 | the annotations, and options to take gene-length or spatial clustering of | |
3824 | genes into account. It is also possible to provide custom gene coordinates, | |
3825 | annotations and ontologies.") | |
3826 | (license license:gpl2+))) | |
9bf4bb19 RW |
3827 | |
3828 | (define-public r-abaenrichment | |
3829 | (package | |
3830 | (name "r-abaenrichment") | |
d6158ecb | 3831 | (version "1.14.1") |
9bf4bb19 RW |
3832 | (source |
3833 | (origin | |
3834 | (method url-fetch) | |
3835 | (uri (bioconductor-uri "ABAEnrichment" version)) | |
3836 | (sha256 | |
3837 | (base32 | |
d6158ecb | 3838 | "1w322wsp6bd3gyfwzgdf088cvfmpq774knr57d0dj420ljf4xn48")))) |
9bf4bb19 RW |
3839 | (properties `((upstream-name . "ABAEnrichment"))) |
3840 | (build-system r-build-system) | |
3841 | (propagated-inputs | |
3842 | `(("r-abadata" ,r-abadata) | |
3843 | ("r-data-table" ,r-data-table) | |
3844 | ("r-gofuncr" ,r-gofuncr) | |
3845 | ("r-gplots" ,r-gplots) | |
3846 | ("r-gtools" ,r-gtools) | |
3847 | ("r-rcpp" ,r-rcpp))) | |
3848 | (home-page "https://bioconductor.org/packages/ABAEnrichment/") | |
3849 | (synopsis "Gene expression enrichment in human brain regions") | |
3850 | (description | |
3851 | "The package ABAEnrichment is designed to test for enrichment of user | |
3852 | defined candidate genes in the set of expressed genes in different human brain | |
3853 | regions. The core function @code{aba_enrich} integrates the expression of the | |
3854 | candidate gene set (averaged across donors) and the structural information of | |
3855 | the brain using an ontology, both provided by the Allen Brain Atlas project.") | |
3856 | (license license:gpl2+))) | |
0b91b7b9 RW |
3857 | |
3858 | (define-public r-annotationfuncs | |
3859 | (package | |
3860 | (name "r-annotationfuncs") | |
69a2ec54 | 3861 | (version "1.34.0") |
0b91b7b9 RW |
3862 | (source |
3863 | (origin | |
3864 | (method url-fetch) | |
3865 | (uri (bioconductor-uri "AnnotationFuncs" version)) | |
3866 | (sha256 | |
3867 | (base32 | |
69a2ec54 | 3868 | "12vh07x8s9y74h65q1pnjlma752pz29bmyyhlnqaiy83gsg26hm3")))) |
0b91b7b9 RW |
3869 | (properties |
3870 | `((upstream-name . "AnnotationFuncs"))) | |
3871 | (build-system r-build-system) | |
3872 | (propagated-inputs | |
3873 | `(("r-annotationdbi" ,r-annotationdbi) | |
3874 | ("r-dbi" ,r-dbi))) | |
3875 | (home-page "https://www.iysik.com/r/annotationfuncs") | |
3876 | (synopsis "Annotation translation functions") | |
3877 | (description | |
3878 | "This package provides functions for handling translating between | |
3879 | different identifieres using the Biocore Data Team data-packages (e.g. | |
3880 | @code{org.Bt.eg.db}).") | |
3881 | (license license:gpl2))) | |
adf7d813 RW |
3882 | |
3883 | (define-public r-annotationtools | |
3884 | (package | |
3885 | (name "r-annotationtools") | |
ee1a45d7 | 3886 | (version "1.58.0") |
adf7d813 RW |
3887 | (source |
3888 | (origin | |
3889 | (method url-fetch) | |
3890 | (uri (bioconductor-uri "annotationTools" version)) | |
3891 | (sha256 | |
3892 | (base32 | |
ee1a45d7 | 3893 | "148fi8bv1m0y81psm0jv1nqvjhvr461drnl0krqd7skcf0mb0fc1")))) |
adf7d813 RW |
3894 | (properties |
3895 | `((upstream-name . "annotationTools"))) | |
3896 | (build-system r-build-system) | |
3897 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
3898 | (home-page "https://bioconductor.org/packages/annotationTools/") | |
3899 | (synopsis "Annotate microarrays and perform gene expression analyses") | |
3900 | (description | |
3901 | "This package provides functions to annotate microarrays, find orthologs, | |
3902 | and integrate heterogeneous gene expression profiles using annotation and | |
3903 | other molecular biology information available as flat file database (plain | |
3904 | text files).") | |
3905 | ;; Any version of the GPL. | |
3906 | (license (list license:gpl2+)))) | |
f31e10f8 RW |
3907 | |
3908 | (define-public r-allelicimbalance | |
3909 | (package | |
3910 | (name "r-allelicimbalance") | |
9da2021f | 3911 | (version "1.22.0") |
f31e10f8 RW |
3912 | (source |
3913 | (origin | |
3914 | (method url-fetch) | |
3915 | (uri (bioconductor-uri "AllelicImbalance" version)) | |
3916 | (sha256 | |
3917 | (base32 | |
9da2021f | 3918 | "1f51y8zjgz0wdd33qbs1gpnadbprixr4wcfvff6v3s09rmnr8fng")))) |
f31e10f8 RW |
3919 | (properties |
3920 | `((upstream-name . "AllelicImbalance"))) | |
3921 | (build-system r-build-system) | |
3922 | (propagated-inputs | |
3923 | `(("r-annotationdbi" ,r-annotationdbi) | |
3924 | ("r-biocgenerics" ,r-biocgenerics) | |
3925 | ("r-biostrings" ,r-biostrings) | |
3926 | ("r-bsgenome" ,r-bsgenome) | |
3927 | ("r-genomeinfodb" ,r-genomeinfodb) | |
3928 | ("r-genomicalignments" ,r-genomicalignments) | |
3929 | ("r-genomicfeatures" ,r-genomicfeatures) | |
3930 | ("r-genomicranges" ,r-genomicranges) | |
3931 | ("r-gridextra" ,r-gridextra) | |
3932 | ("r-gviz" ,r-gviz) | |
3933 | ("r-iranges" ,r-iranges) | |
3934 | ("r-lattice" ,r-lattice) | |
3935 | ("r-latticeextra" ,r-latticeextra) | |
3936 | ("r-nlme" ,r-nlme) | |
3937 | ("r-rsamtools" ,r-rsamtools) | |
3938 | ("r-s4vectors" ,r-s4vectors) | |
3939 | ("r-seqinr" ,r-seqinr) | |
3940 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
3941 | ("r-variantannotation" ,r-variantannotation))) | |
3942 | (home-page "https://github.com/pappewaio/AllelicImbalance") | |
3943 | (synopsis "Investigate allele-specific expression") | |
3944 | (description | |
3945 | "This package provides a framework for allele-specific expression | |
3946 | investigation using RNA-seq data.") | |
3947 | (license license:gpl3))) | |
ffe7029b RW |
3948 | |
3949 | (define-public r-aucell | |
3950 | (package | |
3951 | (name "r-aucell") | |
61730c3d | 3952 | (version "1.6.1") |
ffe7029b RW |
3953 | (source |
3954 | (origin | |
3955 | (method url-fetch) | |
3956 | (uri (bioconductor-uri "AUCell" version)) | |
3957 | (sha256 | |
3958 | (base32 | |
61730c3d | 3959 | "1vd8w6dygn1b5bwlha09mm6fbwyj07pmawpv53agcg1y7jlxs31b")))) |
ffe7029b RW |
3960 | (properties `((upstream-name . "AUCell"))) |
3961 | (build-system r-build-system) | |
3962 | (propagated-inputs | |
3963 | `(("r-data-table" ,r-data-table) | |
3964 | ("r-gseabase" ,r-gseabase) | |
3965 | ("r-mixtools" ,r-mixtools) | |
3966 | ("r-r-utils" ,r-r-utils) | |
3967 | ("r-shiny" ,r-shiny) | |
3968 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
3969 | (home-page "https://bioconductor.org/packages/AUCell/") | |
3970 | (synopsis "Analysis of gene set activity in single-cell RNA-seq data") | |
3971 | (description | |
3972 | "AUCell allows to identify cells with active gene sets (e.g. signatures, | |
3973 | gene modules, etc) in single-cell RNA-seq data. AUCell uses the @dfn{Area | |
3974 | Under the Curve} (AUC) to calculate whether a critical subset of the input | |
3975 | gene set is enriched within the expressed genes for each cell. The | |
3976 | distribution of AUC scores across all the cells allows exploring the relative | |
3977 | expression of the signature. Since the scoring method is ranking-based, | |
3978 | AUCell is independent of the gene expression units and the normalization | |
3979 | procedure. In addition, since the cells are evaluated individually, it can | |
3980 | easily be applied to bigger datasets, subsetting the expression matrix if | |
3981 | needed.") | |
3982 | (license license:gpl3))) | |
5cfa4bff RW |
3983 | |
3984 | (define-public r-ebimage | |
3985 | (package | |
3986 | (name "r-ebimage") | |
2a6d8383 | 3987 | (version "4.26.0") |
5cfa4bff RW |
3988 | (source |
3989 | (origin | |
3990 | (method url-fetch) | |
3991 | (uri (bioconductor-uri "EBImage" version)) | |
3992 | (sha256 | |
3993 | (base32 | |
2a6d8383 | 3994 | "0c8rfi40959rbpbizpiizkq21az3lfwf2azlj55yz5m61qp7mgsq")))) |
5cfa4bff RW |
3995 | (properties `((upstream-name . "EBImage"))) |
3996 | (build-system r-build-system) | |
3997 | (propagated-inputs | |
3998 | `(("r-abind" ,r-abind) | |
3999 | ("r-biocgenerics" ,r-biocgenerics) | |
4000 | ("r-fftwtools" ,r-fftwtools) | |
4001 | ("r-htmltools" ,r-htmltools) | |
4002 | ("r-htmlwidgets" ,r-htmlwidgets) | |
4003 | ("r-jpeg" ,r-jpeg) | |
4004 | ("r-locfit" ,r-locfit) | |
4005 | ("r-png" ,r-png) | |
4006 | ("r-rcurl" ,r-rcurl) | |
4007 | ("r-tiff" ,r-tiff))) | |
4008 | (native-inputs | |
4009 | `(("r-knitr" ,r-knitr))) ; for vignettes | |
4010 | (home-page "https://github.com/aoles/EBImage") | |
4011 | (synopsis "Image processing and analysis toolbox for R") | |
4012 | (description | |
4013 | "EBImage provides general purpose functionality for image processing and | |
4014 | analysis. In the context of (high-throughput) microscopy-based cellular | |
4015 | assays, EBImage offers tools to segment cells and extract quantitative | |
4016 | cellular descriptors. This allows the automation of such tasks using the R | |
4017 | programming language and facilitates the use of other tools in the R | |
4018 | environment for signal processing, statistical modeling, machine learning and | |
4019 | visualization with image data.") | |
4020 | ;; Any version of the LGPL. | |
4021 | (license license:lgpl2.1+))) | |
51e98f7e RW |
4022 | |
4023 | (define-public r-yamss | |
4024 | (package | |
4025 | (name "r-yamss") | |
1269a926 | 4026 | (version "1.10.0") |
51e98f7e RW |
4027 | (source |
4028 | (origin | |
4029 | (method url-fetch) | |
4030 | (uri (bioconductor-uri "yamss" version)) | |
4031 | (sha256 | |
4032 | (base32 | |
1269a926 | 4033 | "00756szrmfm1jdayl90jgblydn6sick9nagdf77pn7wzh6wlaj23")))) |
51e98f7e RW |
4034 | (build-system r-build-system) |
4035 | (propagated-inputs | |
4036 | `(("r-biocgenerics" ,r-biocgenerics) | |
4037 | ("r-data-table" ,r-data-table) | |
4038 | ("r-ebimage" ,r-ebimage) | |
4039 | ("r-iranges" ,r-iranges) | |
4040 | ("r-limma" ,r-limma) | |
4041 | ("r-matrix" ,r-matrix) | |
4042 | ("r-mzr" ,r-mzr) | |
4043 | ("r-s4vectors" ,r-s4vectors) | |
4044 | ("r-summarizedexperiment" | |
4045 | ,r-summarizedexperiment))) | |
4046 | (home-page "https://github.com/hansenlab/yamss") | |
4047 | (synopsis "Tools for high-throughput metabolomics") | |
4048 | (description | |
4049 | "This package provides tools to analyze and visualize high-throughput | |
9b19734c | 4050 | metabolomics data acquired using chromatography-mass spectrometry. These tools |
51e98f7e RW |
4051 | preprocess data in a way that enables reliable and powerful differential |
4052 | analysis.") | |
4053 | (license license:artistic2.0))) | |
398c4a93 RW |
4054 | |
4055 | (define-public r-gtrellis | |
4056 | (package | |
4057 | (name "r-gtrellis") | |
f8fb5b75 | 4058 | (version "1.16.1") |
398c4a93 RW |
4059 | (source |
4060 | (origin | |
4061 | (method url-fetch) | |
4062 | (uri (bioconductor-uri "gtrellis" version)) | |
4063 | (sha256 | |
4064 | (base32 | |
f8fb5b75 | 4065 | "069hln9vflyxic24bxrlmdmz9h3jdd2qaqy898rgk5bn0gqwcjix")))) |
398c4a93 RW |
4066 | (build-system r-build-system) |
4067 | (propagated-inputs | |
4068 | `(("r-circlize" ,r-circlize) | |
4069 | ("r-genomicranges" ,r-genomicranges) | |
4070 | ("r-getoptlong" ,r-getoptlong) | |
4071 | ("r-iranges" ,r-iranges))) | |
4072 | (home-page "https://github.com/jokergoo/gtrellis") | |
4073 | (synopsis "Genome level Trellis layout") | |
4074 | (description | |
4075 | "Genome level Trellis graph visualizes genomic data conditioned by | |
4076 | genomic categories (e.g. chromosomes). For each genomic category, multiple | |
4077 | dimensional data which are represented as tracks describe different features | |
4078 | from different aspects. This package provides high flexibility to arrange | |
4079 | genomic categories and to add self-defined graphics in the plot.") | |
4080 | (license license:expat))) | |
28098414 RW |
4081 | |
4082 | (define-public r-somaticsignatures | |
4083 | (package | |
4084 | (name "r-somaticsignatures") | |
3cdc5d1a | 4085 | (version "2.20.0") |
28098414 RW |
4086 | (source |
4087 | (origin | |
4088 | (method url-fetch) | |
4089 | (uri (bioconductor-uri "SomaticSignatures" version)) | |
4090 | (sha256 | |
4091 | (base32 | |
3cdc5d1a | 4092 | "0wc4ddwngvkc9jhihzaxx8yazqncl1kbgkx8vqn5gd4w2hx0h5bx")))) |
28098414 RW |
4093 | (properties |
4094 | `((upstream-name . "SomaticSignatures"))) | |
4095 | (build-system r-build-system) | |
4096 | (propagated-inputs | |
4097 | `(("r-biobase" ,r-biobase) | |
4098 | ("r-biostrings" ,r-biostrings) | |
4099 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4100 | ("r-genomicranges" ,r-genomicranges) | |
4101 | ("r-ggbio" ,r-ggbio) | |
4102 | ("r-ggplot2" ,r-ggplot2) | |
4103 | ("r-iranges" ,r-iranges) | |
4104 | ("r-nmf" ,r-nmf) | |
4105 | ("r-pcamethods" ,r-pcamethods) | |
4106 | ("r-proxy" ,r-proxy) | |
4107 | ("r-reshape2" ,r-reshape2) | |
4108 | ("r-s4vectors" ,r-s4vectors) | |
4109 | ("r-variantannotation" ,r-variantannotation))) | |
4110 | (home-page "https://github.com/juliangehring/SomaticSignatures") | |
4111 | (synopsis "Somatic signatures") | |
4112 | (description | |
4113 | "This package identifies mutational signatures of @dfn{single nucleotide | |
4114 | variants} (SNVs). It provides a infrastructure related to the methodology | |
4115 | described in Nik-Zainal (2012, Cell), with flexibility in the matrix | |
4116 | decomposition algorithms.") | |
4117 | (license license:expat))) | |
303f2ed1 RW |
4118 | |
4119 | (define-public r-yapsa | |
4120 | (package | |
4121 | (name "r-yapsa") | |
edba69b2 | 4122 | (version "1.10.0") |
303f2ed1 RW |
4123 | (source |
4124 | (origin | |
4125 | (method url-fetch) | |
4126 | (uri (bioconductor-uri "YAPSA" version)) | |
4127 | (sha256 | |
4128 | (base32 | |
edba69b2 | 4129 | "0rfjn2x6hsqiigd53bnl7z5ix5s2mbpr9glsyihsa7i6iazh3n1q")))) |
303f2ed1 RW |
4130 | (properties `((upstream-name . "YAPSA"))) |
4131 | (build-system r-build-system) | |
4132 | (propagated-inputs | |
4133 | `(("r-circlize" ,r-circlize) | |
4134 | ("r-complexheatmap" ,r-complexheatmap) | |
4135 | ("r-corrplot" ,r-corrplot) | |
4136 | ("r-dendextend" ,r-dendextend) | |
4137 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4138 | ("r-genomicranges" ,r-genomicranges) | |
4139 | ("r-getoptlong" ,r-getoptlong) | |
4140 | ("r-ggplot2" ,r-ggplot2) | |
4141 | ("r-gridextra" ,r-gridextra) | |
4142 | ("r-gtrellis" ,r-gtrellis) | |
4143 | ("r-keggrest" ,r-keggrest) | |
4144 | ("r-lsei" ,r-lsei) | |
4145 | ("r-pmcmr" ,r-pmcmr) | |
4146 | ("r-reshape2" ,r-reshape2) | |
4147 | ("r-somaticsignatures" ,r-somaticsignatures) | |
4148 | ("r-variantannotation" ,r-variantannotation))) | |
4149 | (home-page "https://bioconductor.org/packages/YAPSA/") | |
4150 | (synopsis "Yet another package for signature analysis") | |
4151 | (description | |
4152 | "This package provides functions and routines useful in the analysis of | |
4153 | somatic signatures (cf. L. Alexandrov et al., Nature 2013). In particular, | |
4154 | functions to perform a signature analysis with known signatures and a | |
4155 | signature analysis on @dfn{stratified mutational catalogue} (SMC) are | |
4156 | provided.") | |
4157 | (license license:gpl3))) | |
e99380d6 RW |
4158 | |
4159 | (define-public r-gcrma | |
4160 | (package | |
4161 | (name "r-gcrma") | |
56576bea | 4162 | (version "2.56.0") |
e99380d6 RW |
4163 | (source |
4164 | (origin | |
4165 | (method url-fetch) | |
4166 | (uri (bioconductor-uri "gcrma" version)) | |
4167 | (sha256 | |
4168 | (base32 | |
56576bea | 4169 | "1wazr3f4hwzpd0cjs2nlnzifr2g1r8a692pxap9xnmrw66zq94s4")))) |
e99380d6 RW |
4170 | (build-system r-build-system) |
4171 | (propagated-inputs | |
4172 | `(("r-affy" ,r-affy) | |
4173 | ("r-affyio" ,r-affyio) | |
4174 | ("r-biobase" ,r-biobase) | |
4175 | ("r-biocmanager" ,r-biocmanager) | |
4176 | ("r-biostrings" ,r-biostrings) | |
4177 | ("r-xvector" ,r-xvector))) | |
4178 | (home-page "https://bioconductor.org/packages/gcrma/") | |
4179 | (synopsis "Background adjustment using sequence information") | |
4180 | (description | |
4181 | "Gcrma adjusts for background intensities in Affymetrix array data which | |
4182 | include optical noise and @dfn{non-specific binding} (NSB). The main function | |
4183 | @code{gcrma} converts background adjusted probe intensities to expression | |
4184 | measures using the same normalization and summarization methods as a | |
4185 | @dfn{Robust Multiarray Average} (RMA). Gcrma uses probe sequence information | |
4186 | to estimate probe affinity to NSB. The sequence information is summarized in | |
4187 | a more complex way than the simple GC content. Instead, the base types (A, T, | |
4188 | G or C) at each position along the probe determine the affinity of each probe. | |
4189 | The parameters of the position-specific base contributions to the probe | |
4190 | affinity is estimated in an NSB experiment in which only NSB but no | |
4191 | gene-specific bidning is expected.") | |
4192 | ;; Any version of the LGPL | |
4193 | (license license:lgpl2.1+))) | |
4675b3cf RW |
4194 | |
4195 | (define-public r-simpleaffy | |
4196 | (package | |
4197 | (name "r-simpleaffy") | |
38c5d13a | 4198 | (version "2.60.0") |
4675b3cf RW |
4199 | (source |
4200 | (origin | |
4201 | (method url-fetch) | |
4202 | (uri (bioconductor-uri "simpleaffy" version)) | |
4203 | (sha256 | |
4204 | (base32 | |
38c5d13a | 4205 | "0zjpbjkk27w56mrxsxynkqc298xxsarsnzbd7injg6zakhlmhy6a")))) |
4675b3cf RW |
4206 | (build-system r-build-system) |
4207 | (propagated-inputs | |
4208 | `(("r-affy" ,r-affy) | |
4209 | ("r-biobase" ,r-biobase) | |
4210 | ("r-biocgenerics" ,r-biocgenerics) | |
4211 | ("r-gcrma" ,r-gcrma) | |
4212 | ("r-genefilter" ,r-genefilter))) | |
4213 | (home-page "https://bioconductor.org/packages/simpleaffy/") | |
4214 | (synopsis "Very simple high level analysis of Affymetrix data") | |
4215 | (description | |
4216 | "This package provides high level functions for reading Affy @file{.CEL} | |
4217 | files, phenotypic data, and then computing simple things with it, such as | |
4218 | t-tests, fold changes and the like. It makes heavy use of the @code{affy} | |
4219 | library. It also has some basic scatter plot functions and mechanisms for | |
4220 | generating high resolution journal figures.") | |
4221 | (license license:gpl2+))) | |
f562c90a RW |
4222 | |
4223 | (define-public r-yaqcaffy | |
4224 | (package | |
4225 | (name "r-yaqcaffy") | |
f48e29da | 4226 | (version "1.44.0") |
f562c90a RW |
4227 | (source |
4228 | (origin | |
4229 | (method url-fetch) | |
4230 | (uri (bioconductor-uri "yaqcaffy" version)) | |
4231 | (sha256 | |
4232 | (base32 | |
f48e29da | 4233 | "1v12mbai6gf7wpxbyz4clvr7w1mlbv3scjf4kydfin8wwrrzq670")))) |
f562c90a RW |
4234 | (build-system r-build-system) |
4235 | (propagated-inputs | |
4236 | `(("r-simpleaffy" ,r-simpleaffy))) | |
4237 | (home-page "https://bioconductor.org/packages/yaqcaffy/") | |
4238 | (synopsis "Affymetrix quality control and reproducibility analysis") | |
4239 | (description | |
4240 | "This is a package that can be used for quality control of Affymetrix | |
4241 | GeneChip expression data and reproducibility analysis of human whole genome | |
4242 | chips with the MAQC reference datasets.") | |
4243 | (license license:artistic2.0))) | |
59cf2629 RW |
4244 | |
4245 | (define-public r-quantro | |
4246 | (package | |
4247 | (name "r-quantro") | |
2feea2d2 | 4248 | (version "1.18.0") |
59cf2629 RW |
4249 | (source |
4250 | (origin | |
4251 | (method url-fetch) | |
4252 | (uri (bioconductor-uri "quantro" version)) | |
4253 | (sha256 | |
4254 | (base32 | |
2feea2d2 | 4255 | "0zfb2s410ijp0didapnq7q4gn2d26wy785cygxyvg8sq6mlw2cab")))) |
59cf2629 RW |
4256 | (build-system r-build-system) |
4257 | (propagated-inputs | |
4258 | `(("r-biobase" ,r-biobase) | |
4259 | ("r-doparallel" ,r-doparallel) | |
4260 | ("r-foreach" ,r-foreach) | |
4261 | ("r-ggplot2" ,r-ggplot2) | |
4262 | ("r-iterators" ,r-iterators) | |
4263 | ("r-minfi" ,r-minfi) | |
4264 | ("r-rcolorbrewer" ,r-rcolorbrewer))) | |
4265 | (home-page "https://bioconductor.org/packages/quantro/") | |
4266 | (synopsis "Test for when to use quantile normalization") | |
4267 | (description | |
4268 | "This package provides a data-driven test for the assumptions of quantile | |
4269 | normalization using raw data such as objects that inherit eSets (e.g. | |
4270 | ExpressionSet, MethylSet). Group level information about each sample (such as | |
4271 | Tumor / Normal status) must also be provided because the test assesses if | |
4272 | there are global differences in the distributions between the user-defined | |
4273 | groups.") | |
4274 | (license license:gpl3+))) | |
98a2af31 RW |
4275 | |
4276 | (define-public r-yarn | |
4277 | (package | |
4278 | (name "r-yarn") | |
7f4957b2 | 4279 | (version "1.10.0") |
98a2af31 RW |
4280 | (source |
4281 | (origin | |
4282 | (method url-fetch) | |
4283 | (uri (bioconductor-uri "yarn" version)) | |
4284 | (sha256 | |
4285 | (base32 | |
7f4957b2 | 4286 | "00gmwylpdmssz8xpd91d8fsiyglr7f9vc9bdalpa7w5vg4c6d2f6")))) |
98a2af31 RW |
4287 | (build-system r-build-system) |
4288 | (propagated-inputs | |
4289 | `(("r-biobase" ,r-biobase) | |
4290 | ("r-biomart" ,r-biomart) | |
4291 | ("r-downloader" ,r-downloader) | |
4292 | ("r-edger" ,r-edger) | |
4293 | ("r-gplots" ,r-gplots) | |
4294 | ("r-limma" ,r-limma) | |
4295 | ("r-matrixstats" ,r-matrixstats) | |
4296 | ("r-preprocesscore" ,r-preprocesscore) | |
4297 | ("r-quantro" ,r-quantro) | |
4298 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
4299 | ("r-readr" ,r-readr))) | |
4300 | (home-page "https://bioconductor.org/packages/yarn/") | |
4301 | (synopsis "Robust multi-condition RNA-Seq preprocessing and normalization") | |
4302 | (description | |
4303 | "Expedite large RNA-Seq analyses using a combination of previously | |
4304 | developed tools. YARN is meant to make it easier for the user in performing | |
4305 | basic mis-annotation quality control, filtering, and condition-aware | |
4306 | normalization. YARN leverages many Bioconductor tools and statistical | |
4307 | techniques to account for the large heterogeneity and sparsity found in very | |
4308 | large RNA-seq experiments.") | |
4309 | (license license:artistic2.0))) | |
a6e1eb1a RW |
4310 | |
4311 | (define-public r-roar | |
4312 | (package | |
4313 | (name "r-roar") | |
0334b203 | 4314 | (version "1.20.0") |
a6e1eb1a RW |
4315 | (source |
4316 | (origin | |
4317 | (method url-fetch) | |
4318 | (uri (bioconductor-uri "roar" version)) | |
4319 | (sha256 | |
4320 | (base32 | |
0334b203 | 4321 | "11ib5vr2vrrqsqcikph528c56bp52myyfdlwkklp8m0r15kwpxr7")))) |
a6e1eb1a RW |
4322 | (build-system r-build-system) |
4323 | (propagated-inputs | |
4324 | `(("r-biocgenerics" ,r-biocgenerics) | |
4325 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4326 | ("r-genomicalignments" ,r-genomicalignments) | |
4327 | ("r-genomicranges" ,r-genomicranges) | |
4328 | ("r-iranges" ,r-iranges) | |
4329 | ("r-rtracklayer" ,r-rtracklayer) | |
4330 | ("r-s4vectors" ,r-s4vectors) | |
4331 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
4332 | (home-page "https://github.com/vodkatad/roar/") | |
4333 | (synopsis "Identify differential APA usage from RNA-seq alignments") | |
4334 | (description | |
4335 | "This package provides tools for identifying preferential usage of APA | |
4336 | sites, comparing two biological conditions, starting from known alternative | |
4337 | sites and alignments obtained from standard RNA-seq experiments.") | |
4338 | (license license:gpl3))) | |
50d91770 RW |
4339 | |
4340 | (define-public r-xbseq | |
4341 | (package | |
4342 | (name "r-xbseq") | |
88469def | 4343 | (version "1.16.0") |
50d91770 RW |
4344 | (source |
4345 | (origin | |
4346 | (method url-fetch) | |
4347 | (uri (bioconductor-uri "XBSeq" version)) | |
4348 | (sha256 | |
4349 | (base32 | |
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50d91770 RW |
4351 | (properties `((upstream-name . "XBSeq"))) |
4352 | (build-system r-build-system) | |
4353 | (propagated-inputs | |
4354 | `(("r-biobase" ,r-biobase) | |
4355 | ("r-deseq2" ,r-deseq2) | |
4356 | ("r-dplyr" ,r-dplyr) | |
4357 | ("r-ggplot2" ,r-ggplot2) | |
4358 | ("r-locfit" ,r-locfit) | |
4359 | ("r-magrittr" ,r-magrittr) | |
4360 | ("r-matrixstats" ,r-matrixstats) | |
4361 | ("r-pracma" ,r-pracma) | |
4362 | ("r-roar" ,r-roar))) | |
4363 | (home-page "https://github.com/Liuy12/XBSeq") | |
4364 | (synopsis "Test for differential expression for RNA-seq data") | |
4365 | (description | |
4366 | "XBSeq is a novel algorithm for testing RNA-seq @dfn{differential | |
4367 | expression} (DE), where a statistical model was established based on the | |
4368 | assumption that observed signals are the convolution of true expression | |
4369 | signals and sequencing noises. The mapped reads in non-exonic regions are | |
4370 | considered as sequencing noises, which follows a Poisson distribution. Given | |
4371 | measurable observed signal and background noise from RNA-seq data, true | |
4372 | expression signals, assuming governed by the negative binomial distribution, | |
4373 | can be delineated and thus the accurate detection of differential expressed | |
4374 | genes.") | |
4375 | (license license:gpl3+))) | |
c8310056 RW |
4376 | |
4377 | (define-public r-massspecwavelet | |
4378 | (package | |
4379 | (name "r-massspecwavelet") | |
7c888138 | 4380 | (version "1.50.0") |
c8310056 RW |
4381 | (source |
4382 | (origin | |
4383 | (method url-fetch) | |
4384 | (uri (bioconductor-uri "MassSpecWavelet" version)) | |
4385 | (sha256 | |
4386 | (base32 | |
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c8310056 RW |
4388 | (properties |
4389 | `((upstream-name . "MassSpecWavelet"))) | |
4390 | (build-system r-build-system) | |
4391 | (propagated-inputs | |
4392 | `(("r-waveslim" ,r-waveslim))) | |
4393 | (home-page "https://bioconductor.org/packages/MassSpecWavelet/") | |
4394 | (synopsis "Mass spectrum processing by wavelet-based algorithms") | |
4395 | (description | |
4396 | "The MassSpecWavelet package aims to process @dfn{Mass Spectrometry} (MS) | |
4397 | data mainly through the use of wavelet transforms. It supports peak detection | |
4398 | based on @dfn{Continuous Wavelet Transform} (CWT).") | |
4399 | (license license:lgpl2.0+))) | |
ec12e537 RW |
4400 | |
4401 | (define-public r-xcms | |
4402 | (package | |
4403 | (name "r-xcms") | |
40b2f7bc | 4404 | (version "3.6.1") |
ec12e537 RW |
4405 | (source |
4406 | (origin | |
4407 | (method url-fetch) | |
4408 | (uri (bioconductor-uri "xcms" version)) | |
4409 | (sha256 | |
4410 | (base32 | |
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ec12e537 RW |
4412 | (build-system r-build-system) |
4413 | (propagated-inputs | |
4414 | `(("r-biobase" ,r-biobase) | |
4415 | ("r-biocgenerics" ,r-biocgenerics) | |
4416 | ("r-biocparallel" ,r-biocparallel) | |
4417 | ("r-lattice" ,r-lattice) | |
4418 | ("r-massspecwavelet" ,r-massspecwavelet) | |
4419 | ("r-msnbase" ,r-msnbase) | |
4420 | ("r-multtest" ,r-multtest) | |
4421 | ("r-mzr" ,r-mzr) | |
4422 | ("r-plyr" ,r-plyr) | |
4423 | ("r-protgenerics" ,r-protgenerics) | |
4424 | ("r-rann" ,r-rann) | |
4425 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
4426 | ("r-robustbase" ,r-robustbase) | |
4427 | ("r-s4vectors" ,r-s4vectors))) | |
4428 | (home-page "https://bioconductor.org/packages/xcms/") | |
4429 | (synopsis "LC/MS and GC/MS mass spectrometry data analysis") | |
4430 | (description | |
4431 | "This package provides a framework for processing and visualization of | |
4432 | chromatographically separated and single-spectra mass spectral data. It | |
4433 | imports from AIA/ANDI NetCDF, mzXML, mzData and mzML files. It preprocesses | |
4434 | data for high-throughput, untargeted analyte profiling.") | |
4435 | (license license:gpl2+))) | |
8830664d RW |
4436 | |
4437 | (define-public r-wrench | |
4438 | (package | |
4439 | (name "r-wrench") | |
07597c85 | 4440 | (version "1.2.0") |
8830664d RW |
4441 | (source |
4442 | (origin | |
4443 | (method url-fetch) | |
4444 | (uri (bioconductor-uri "Wrench" version)) | |
4445 | (sha256 | |
4446 | (base32 | |
07597c85 | 4447 | "1js4dsgpgwq552r4ay78awd5vhzlmva0v8xvn3dy9v18y4j9k94i")))) |
8830664d RW |
4448 | (properties `((upstream-name . "Wrench"))) |
4449 | (build-system r-build-system) | |
4450 | (propagated-inputs | |
4451 | `(("r-limma" ,r-limma) | |
4452 | ("r-locfit" ,r-locfit) | |
4453 | ("r-matrixstats" ,r-matrixstats))) | |
4454 | (home-page "https://github.com/HCBravoLab/Wrench") | |
4455 | (synopsis "Wrench normalization for sparse count data") | |
4456 | (description | |
4457 | "Wrench is a package for normalization sparse genomic count data, like | |
4458 | that arising from 16s metagenomic surveys.") | |
4459 | (license license:artistic2.0))) | |
b9b8b447 RW |
4460 | |
4461 | (define-public r-wiggleplotr | |
4462 | (package | |
4463 | (name "r-wiggleplotr") | |
a6edf335 | 4464 | (version "1.8.0") |
b9b8b447 RW |
4465 | (source |
4466 | (origin | |
4467 | (method url-fetch) | |
4468 | (uri (bioconductor-uri "wiggleplotr" version)) | |
4469 | (sha256 | |
4470 | (base32 | |
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b9b8b447 RW |
4472 | (build-system r-build-system) |
4473 | (propagated-inputs | |
4474 | `(("r-assertthat" ,r-assertthat) | |
4475 | ("r-cowplot" ,r-cowplot) | |
4476 | ("r-dplyr" ,r-dplyr) | |
4477 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4478 | ("r-genomicranges" ,r-genomicranges) | |
4479 | ("r-ggplot2" ,r-ggplot2) | |
4480 | ("r-iranges" ,r-iranges) | |
4481 | ("r-purrr" ,r-purrr) | |
4482 | ("r-rtracklayer" ,r-rtracklayer) | |
4483 | ("r-s4vectors" ,r-s4vectors))) | |
4484 | (home-page "https://bioconductor.org/packages/wiggleplotr/") | |
4485 | (synopsis "Make read coverage plots from BigWig files") | |
4486 | (description | |
4487 | "This package provides tools to visualize read coverage from sequencing | |
4488 | experiments together with genomic annotations (genes, transcripts, peaks). | |
4489 | Introns of long transcripts can be rescaled to a fixed length for better | |
4490 | visualization of exonic read coverage.") | |
4491 | (license license:asl2.0))) | |
7b5101c5 RW |
4492 | |
4493 | (define-public r-widgettools | |
4494 | (package | |
4495 | (name "r-widgettools") | |
c881b9ef | 4496 | (version "1.62.0") |
7b5101c5 RW |
4497 | (source |
4498 | (origin | |
4499 | (method url-fetch) | |
4500 | (uri (bioconductor-uri "widgetTools" version)) | |
4501 | (sha256 | |
4502 | (base32 | |
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7b5101c5 RW |
4504 | (properties `((upstream-name . "widgetTools"))) |
4505 | (build-system r-build-system) | |
4506 | (home-page "https://bioconductor.org/packages/widgetTools/") | |
4507 | (synopsis "Tools for creating interactive tcltk widgets") | |
4508 | (description | |
337bdc17 | 4509 | "This package contains tools to support the construction of tcltk |
7b5101c5 RW |
4510 | widgets in R.") |
4511 | ;; Any version of the LGPL. | |
4512 | (license license:lgpl3+))) | |
6b12f213 RW |
4513 | |
4514 | (define-public r-webbioc | |
4515 | (package | |
4516 | (name "r-webbioc") | |
67bc9255 | 4517 | (version "1.56.0") |
6b12f213 RW |
4518 | (source |
4519 | (origin | |
4520 | (method url-fetch) | |
4521 | (uri (bioconductor-uri "webbioc" version)) | |
4522 | (sha256 | |
4523 | (base32 | |
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6b12f213 RW |
4525 | (build-system r-build-system) |
4526 | (inputs | |
4527 | `(("netpbm" ,netpbm) | |
4528 | ("perl" ,perl))) | |
4529 | (propagated-inputs | |
4530 | `(("r-affy" ,r-affy) | |
4531 | ("r-annaffy" ,r-annaffy) | |
4532 | ("r-biobase" ,r-biobase) | |
4533 | ("r-biocmanager" ,r-biocmanager) | |
4534 | ("r-gcrma" ,r-gcrma) | |
4535 | ("r-multtest" ,r-multtest) | |
4536 | ("r-qvalue" ,r-qvalue) | |
4537 | ("r-vsn" ,r-vsn))) | |
4538 | (home-page "https://www.bioconductor.org/") | |
4539 | (synopsis "Bioconductor web interface") | |
4540 | (description | |
4541 | "This package provides an integrated web interface for doing microarray | |
4542 | analysis using several of the Bioconductor packages. It is intended to be | |
4543 | deployed as a centralized bioinformatics resource for use by many users. | |
4544 | Currently only Affymetrix oligonucleotide analysis is supported.") | |
4545 | (license license:gpl2+))) | |
9800d859 RW |
4546 | |
4547 | (define-public r-zfpkm | |
4548 | (package | |
4549 | (name "r-zfpkm") | |
02530c28 | 4550 | (version "1.6.0") |
9800d859 RW |
4551 | (source |
4552 | (origin | |
4553 | (method url-fetch) | |
4554 | (uri (bioconductor-uri "zFPKM" version)) | |
4555 | (sha256 | |
4556 | (base32 | |
02530c28 | 4557 | "14knxp8cjjp9fhc6py66c7hrckf112jamz3gl1v60l1f2l1hmfvz")))) |
9800d859 RW |
4558 | (properties `((upstream-name . "zFPKM"))) |
4559 | (build-system r-build-system) | |
4560 | (propagated-inputs | |
4561 | `(("r-checkmate" ,r-checkmate) | |
4562 | ("r-dplyr" ,r-dplyr) | |
4563 | ("r-ggplot2" ,r-ggplot2) | |
4564 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
4565 | ("r-tidyr" ,r-tidyr))) | |
4566 | (home-page "https://github.com/ronammar/zFPKM/") | |
4567 | (synopsis "Functions to facilitate zFPKM transformations") | |
4568 | (description | |
4569 | "This is a package to perform the zFPKM transform on RNA-seq FPKM data. | |
4570 | This algorithm is based on the publication by Hart et al., 2013 (Pubmed ID | |
4571 | 24215113).") | |
4572 | (license license:gpl3))) | |
2bdc88fc RW |
4573 | |
4574 | (define-public r-rbowtie2 | |
4575 | (package | |
4576 | (name "r-rbowtie2") | |
7d33d36c | 4577 | (version "1.6.0") |
2bdc88fc RW |
4578 | (source |
4579 | (origin | |
4580 | (method url-fetch) | |
4581 | (uri (bioconductor-uri "Rbowtie2" version)) | |
4582 | (sha256 | |
4583 | (base32 | |
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2bdc88fc RW |
4585 | (properties `((upstream-name . "Rbowtie2"))) |
4586 | (build-system r-build-system) | |
4587 | (inputs | |
4588 | `(("zlib" ,zlib))) | |
4589 | (home-page "https://bioconductor.org/packages/Rbowtie2/") | |
4590 | (synopsis "R wrapper for Bowtie2 and AdapterRemoval") | |
4591 | (description | |
4592 | "This package provides an R wrapper of the popular @code{bowtie2} | |
4593 | sequencing reads aligner and @code{AdapterRemoval}, a convenient tool for | |
4594 | rapid adapter trimming, identification, and read merging.") | |
4595 | (license license:gpl3+))) | |
5622628f RW |
4596 | |
4597 | (define-public r-progeny | |
4598 | (package | |
4599 | (name "r-progeny") | |
c2bfb978 | 4600 | (version "1.6.0") |
5622628f RW |
4601 | (source |
4602 | (origin | |
4603 | (method url-fetch) | |
4604 | (uri (bioconductor-uri "progeny" version)) | |
4605 | (sha256 | |
4606 | (base32 | |
c2bfb978 | 4607 | "03rm90vfb9ivxhapvs3h5yggfazf8bf5vh1krknvb3xyw27br9dw")))) |
5622628f RW |
4608 | (build-system r-build-system) |
4609 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
4610 | (home-page "https://github.com/saezlab/progeny") | |
4611 | (synopsis "Pathway responsive gene activity inference") | |
4612 | (description | |
4613 | "This package provides a function to infer pathway activity from gene | |
4614 | expression. It contains the linear model inferred in the publication | |
4615 | \"Perturbation-response genes reveal signaling footprints in cancer gene | |
4616 | expression\".") | |
4617 | (license license:asl2.0))) | |
307586c1 RW |
4618 | |
4619 | (define-public r-arrmnormalization | |
4620 | (package | |
4621 | (name "r-arrmnormalization") | |
c24adbbf | 4622 | (version "1.24.0") |
307586c1 RW |
4623 | (source |
4624 | (origin | |
4625 | (method url-fetch) | |
4626 | (uri (bioconductor-uri "ARRmNormalization" version)) | |
4627 | (sha256 | |
4628 | (base32 | |
c24adbbf | 4629 | "05m7hy1qd4lr1ylb0ld30dirdl9jfp1zhvifl6wvj40x74b6h2d1")))) |
307586c1 RW |
4630 | (properties |
4631 | `((upstream-name . "ARRmNormalization"))) | |
4632 | (build-system r-build-system) | |
4633 | (propagated-inputs `(("r-arrmdata" ,r-arrmdata))) | |
4634 | (home-page "https://bioconductor.org/packages/ARRmNormalization/") | |
4635 | (synopsis "Adaptive robust regression normalization for methylation data") | |
4636 | (description | |
4637 | "This is a package to perform the @dfn{Adaptive Robust Regression | |
4638 | method} (ARRm) for the normalization of methylation data from the Illumina | |
4639 | Infinium HumanMethylation 450k assay.") | |
4640 | (license license:artistic2.0))) | |
fbf34949 RW |
4641 | |
4642 | (define-public r-biocfilecache | |
4643 | (package | |
4644 | (name "r-biocfilecache") | |
4645 | (version "1.8.0") | |
4646 | (source | |
4647 | (origin | |
4648 | (method url-fetch) | |
4649 | (uri (bioconductor-uri "BiocFileCache" version)) | |
4650 | (sha256 | |
4651 | (base32 | |
4652 | "1mi8p8hvrdxim8lqsid2cb7284imyjf9rlzsrdlzdjac7dp9bpdb")))) | |
4653 | (properties `((upstream-name . "BiocFileCache"))) | |
4654 | (build-system r-build-system) | |
4655 | (propagated-inputs | |
4656 | `(("r-curl" ,r-curl) | |
4657 | ("r-dbi" ,r-dbi) | |
4658 | ("r-dbplyr" ,r-dbplyr) | |
4659 | ("r-dplyr" ,r-dplyr) | |
4660 | ("r-httr" ,r-httr) | |
4661 | ("r-rappdirs" ,r-rappdirs) | |
4662 | ("r-rsqlite" ,r-rsqlite))) | |
4663 | (home-page "https://bioconductor.org/packages/BiocFileCache/") | |
4664 | (synopsis "Manage files across sessions") | |
4665 | (description | |
4666 | "This package creates a persistent on-disk cache of files that the user | |
4667 | can add, update, and retrieve. It is useful for managing resources (such as | |
4668 | custom Txdb objects) that are costly or difficult to create, web resources, | |
4669 | and data files used across sessions.") | |
4670 | (license license:artistic2.0))) | |
8c42f8f6 RW |
4671 | |
4672 | (define-public r-iclusterplus | |
4673 | (package | |
4674 | (name "r-iclusterplus") | |
4675 | (version "1.20.0") | |
4676 | (source | |
4677 | (origin | |
4678 | (method url-fetch) | |
4679 | (uri (bioconductor-uri "iClusterPlus" version)) | |
4680 | (sha256 | |
4681 | (base32 | |
4682 | "14x43jjhbp4zwb4dv9rwrm5l5p7h76bc1zkdbiikqip9bzph0viq")))) | |
4683 | (properties `((upstream-name . "iClusterPlus"))) | |
4684 | (build-system r-build-system) | |
4685 | (native-inputs `(("gfortran" ,gfortran))) | |
4686 | (home-page "https://bioconductor.org/packages/iClusterPlus/") | |
4687 | (synopsis "Integrative clustering of multi-type genomic data") | |
4688 | (description | |
4689 | "iClusterPlus is developed for integrative clustering analysis of | |
4690 | multi-type genomic data and is an enhanced version of iCluster proposed and | |
4691 | developed by Shen, Olshen and Ladanyi (2009). Multi-type genomic data arise | |
4692 | from the experiments where biological samples (e.g. tumor samples) are | |
4693 | analyzed by multiple techniques, for instance, @dfn{array comparative genomic | |
4694 | hybridization} (aCGH), gene expression microarray, RNA-seq and DNA-seq, and so | |
4695 | on. In the iClusterPlus model, binary observations such as somatic mutation | |
4696 | are modeled as Binomial processes; categorical observations such as copy | |
4697 | number states are realizations of Multinomial random variables; counts are | |
4698 | modeled as Poisson random processes; and continuous measures are modeled by | |
4699 | Gaussian distributions.") | |
4700 | (license license:gpl2+))) | |
4d06ef4b RW |
4701 | |
4702 | (define-public r-rbowtie | |
4703 | (package | |
4704 | (name "r-rbowtie") | |
4705 | (version "1.24.0") | |
4706 | (source | |
4707 | (origin | |
4708 | (method url-fetch) | |
4709 | (uri (bioconductor-uri "Rbowtie" version)) | |
4710 | (sha256 | |
4711 | (base32 | |
4712 | "1p8gbd2zn677lq8d009p2cplg1jm2jhn81lppipj638i9ynjh44f")))) | |
4713 | (properties `((upstream-name . "Rbowtie"))) | |
4714 | (build-system r-build-system) | |
4715 | (inputs | |
4716 | `(("zlib" ,zlib))) | |
4717 | (home-page "https://bioconductor.org/packages/Rbowtie/") | |
4718 | (synopsis "R bowtie wrapper") | |
4719 | (description | |
4720 | "This package provides an R wrapper around the popular bowtie short read | |
4721 | aligner and around SpliceMap, a de novo splice junction discovery and | |
4722 | alignment tool.") | |
4723 | (license license:artistic2.0))) | |
14441539 RW |
4724 | |
4725 | (define-public r-sgseq | |
4726 | (package | |
4727 | (name "r-sgseq") | |
4728 | (version "1.18.0") | |
4729 | (source | |
4730 | (origin | |
4731 | (method url-fetch) | |
4732 | (uri (bioconductor-uri "SGSeq" version)) | |
4733 | (sha256 | |
4734 | (base32 | |
4735 | "09c0hv74pl310wahyyp4x50g6sz30bvrg24p2j9h7glla5dh2z4s")))) | |
4736 | (properties `((upstream-name . "SGSeq"))) | |
4737 | (build-system r-build-system) | |
4738 | (propagated-inputs | |
4739 | `(("r-annotationdbi" ,r-annotationdbi) | |
4740 | ("r-biocgenerics" ,r-biocgenerics) | |
4741 | ("r-biostrings" ,r-biostrings) | |
4742 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4743 | ("r-genomicalignments" ,r-genomicalignments) | |
4744 | ("r-genomicfeatures" ,r-genomicfeatures) | |
4745 | ("r-genomicranges" ,r-genomicranges) | |
4746 | ("r-igraph" ,r-igraph) | |
4747 | ("r-iranges" ,r-iranges) | |
4748 | ("r-rsamtools" ,r-rsamtools) | |
4749 | ("r-rtracklayer" ,r-rtracklayer) | |
4750 | ("r-runit" ,r-runit) | |
4751 | ("r-s4vectors" ,r-s4vectors) | |
4752 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
4753 | (home-page "https://bioconductor.org/packages/SGSeq/") | |
4754 | (synopsis "Splice event prediction and quantification from RNA-seq data") | |
4755 | (description | |
4756 | "SGSeq is a package for analyzing splice events from RNA-seq data. Input | |
4757 | data are RNA-seq reads mapped to a reference genome in BAM format. Genes are | |
4758 | represented as a splice graph, which can be obtained from existing annotation | |
4759 | or predicted from the mapped sequence reads. Splice events are identified | |
4760 | from the graph and are quantified locally using structurally compatible reads | |
4761 | at the start or end of each splice variant. The software includes functions | |
4762 | for splice event prediction, quantification, visualization and | |
4763 | interpretation.") | |
4764 | (license license:artistic2.0))) | |
58656064 RW |
4765 | |
4766 | (define-public r-rhisat2 | |
4767 | (package | |
4768 | (name "r-rhisat2") | |
932a6c42 | 4769 | (version "1.0.3") |
58656064 RW |
4770 | (source |
4771 | (origin | |
4772 | (method url-fetch) | |
4773 | (uri (bioconductor-uri "Rhisat2" version)) | |
4774 | (sha256 | |
4775 | (base32 | |
932a6c42 | 4776 | "02ig9qci18n93vmya7q6bijrqsbfh69fyg8iqysf89ym2vd3x3c5")))) |
58656064 RW |
4777 | (properties `((upstream-name . "Rhisat2"))) |
4778 | (build-system r-build-system) | |
4779 | (native-inputs | |
4780 | `(("which" ,which))) | |
4781 | (propagated-inputs | |
4782 | `(("r-genomicfeatures" ,r-genomicfeatures) | |
4783 | ("r-genomicranges" ,r-genomicranges) | |
4784 | ("r-sgseq" ,r-sgseq))) | |
4785 | (home-page "https://github.com/fmicompbio/Rhisat2") | |
4786 | (synopsis "R Wrapper for HISAT2 sequence aligner") | |
4787 | (description | |
4788 | "This package provides an R interface to the HISAT2 spliced short-read | |
4789 | aligner by Kim et al. (2015). The package contains wrapper functions to | |
4790 | create a genome index and to perform the read alignment to the generated | |
4791 | index.") | |
4792 | (license license:gpl3))) | |
5e0241db RW |
4793 | |
4794 | (define-public r-quasr | |
4795 | (package | |
4796 | (name "r-quasr") | |
b3319f4c | 4797 | (version "1.24.2") |
5e0241db RW |
4798 | (source |
4799 | (origin | |
4800 | (method url-fetch) | |
4801 | (uri (bioconductor-uri "QuasR" version)) | |
4802 | (sha256 | |
4803 | (base32 | |
b3319f4c | 4804 | "1pshm41iba9nfq2pigk4dyldn5434w83rhgj99cdjnd0rszj7ajx")))) |
5e0241db RW |
4805 | (properties `((upstream-name . "QuasR"))) |
4806 | (build-system r-build-system) | |
4807 | (inputs | |
4808 | `(("zlib" ,zlib))) | |
4809 | (propagated-inputs | |
4810 | `(("r-annotationdbi" ,r-annotationdbi) | |
4811 | ("r-biobase" ,r-biobase) | |
4812 | ("r-biocgenerics" ,r-biocgenerics) | |
4813 | ("r-biocmanager" ,r-biocmanager) | |
4814 | ("r-biocparallel" ,r-biocparallel) | |
4815 | ("r-biostrings" ,r-biostrings) | |
4816 | ("r-bsgenome" ,r-bsgenome) | |
4817 | ("r-genomeinfodb" ,r-genomeinfodb) | |
4818 | ("r-genomicalignments" ,r-genomicalignments) | |
4819 | ("r-genomicfeatures" ,r-genomicfeatures) | |
4820 | ("r-genomicfiles" ,r-genomicfiles) | |
4821 | ("r-genomicranges" ,r-genomicranges) | |
4822 | ("r-iranges" ,r-iranges) | |
4823 | ("r-rbowtie" ,r-rbowtie) | |
4824 | ("r-rhisat2" ,r-rhisat2) | |
4825 | ("r-rhtslib" ,r-rhtslib) | |
4826 | ("r-rsamtools" ,r-rsamtools) | |
4827 | ("r-rtracklayer" ,r-rtracklayer) | |
4828 | ("r-s4vectors" ,r-s4vectors) | |
4829 | ("r-shortread" ,r-shortread))) | |
4830 | (home-page "https://bioconductor.org/packages/QuasR/") | |
4831 | (synopsis "Quantify and annotate short reads in R") | |
4832 | (description | |
4833 | "This package provides a framework for the quantification and analysis of | |
4834 | short genomic reads. It covers a complete workflow starting from raw sequence | |
4835 | reads, over creation of alignments and quality control plots, to the | |
4836 | quantification of genomic regions of interest.") | |
4837 | (license license:gpl2))) | |
496b024f RW |
4838 | |
4839 | (define-public r-rqc | |
4840 | (package | |
4841 | (name "r-rqc") | |
4842 | (version "1.18.0") | |
4843 | (source | |
4844 | (origin | |
4845 | (method url-fetch) | |
4846 | (uri (bioconductor-uri "Rqc" version)) | |
4847 | (sha256 | |
4848 | (base32 | |
4849 | "09kyn5nc2fqfdm3q07h0x2jyh24vsq5sxxm63ir1lvv250lmal4g")))) | |
4850 | (properties `((upstream-name . "Rqc"))) | |
4851 | (build-system r-build-system) | |
4852 | (propagated-inputs | |
4853 | `(("r-biocgenerics" ,r-biocgenerics) | |
4854 | ("r-biocparallel" ,r-biocparallel) | |
4855 | ("r-biocstyle" ,r-biocstyle) | |
4856 | ("r-biostrings" ,r-biostrings) | |
4857 | ("r-biovizbase" ,r-biovizbase) | |
4858 | ("r-genomicalignments" ,r-genomicalignments) | |
4859 | ("r-genomicfiles" ,r-genomicfiles) | |
4860 | ("r-ggplot2" ,r-ggplot2) | |
4861 | ("r-iranges" ,r-iranges) | |
4862 | ("r-knitr" ,r-knitr) | |
4863 | ("r-markdown" ,r-markdown) | |
4864 | ("r-plyr" ,r-plyr) | |
4865 | ("r-rcpp" ,r-rcpp) | |
4866 | ("r-reshape2" ,r-reshape2) | |
4867 | ("r-rsamtools" ,r-rsamtools) | |
4868 | ("r-s4vectors" ,r-s4vectors) | |
4869 | ("r-shiny" ,r-shiny) | |
4870 | ("r-shortread" ,r-shortread))) | |
4871 | (home-page "https://github.com/labbcb/Rqc") | |
4872 | (synopsis "Quality control tool for high-throughput sequencing data") | |
4873 | (description | |
4874 | "Rqc is an optimized tool designed for quality control and assessment of | |
4875 | high-throughput sequencing data. It performs parallel processing of entire | |
4876 | files and produces a report which contains a set of high-resolution | |
4877 | graphics.") | |
4878 | (license license:gpl2+))) | |
81e3de01 RW |
4879 | |
4880 | (define-public r-birewire | |
4881 | (package | |
4882 | (name "r-birewire") | |
4883 | (version "3.16.0") | |
4884 | (source | |
4885 | (origin | |
4886 | (method url-fetch) | |
4887 | (uri (bioconductor-uri "BiRewire" version)) | |
4888 | (sha256 | |
4889 | (base32 | |
4890 | "1gjb18l3gq3w8zl6r5d49hw0r1kfh9f7ghv9hz6y86aniprvb518")))) | |
4891 | (properties `((upstream-name . "BiRewire"))) | |
4892 | (build-system r-build-system) | |
4893 | (propagated-inputs | |
4894 | `(("r-igraph" ,r-igraph) | |
4895 | ("r-matrix" ,r-matrix) | |
4896 | ("r-slam" ,r-slam) | |
4897 | ("r-tsne" ,r-tsne))) | |
4898 | (home-page "https://bioconductor.org/packages/release/bioc/html/BiRewire.html") | |
4899 | (synopsis "Tools for randomization of bipartite graphs") | |
4900 | (description | |
4901 | "This package provides functions for bipartite network rewiring through N | |
4902 | consecutive switching steps and for the computation of the minimal number of | |
4903 | switching steps to be performed in order to maximise the dissimilarity with | |
4904 | respect to the original network. It includes functions for the analysis of | |
4905 | the introduced randomness across the switching steps and several other | |
4906 | routines to analyse the resulting networks and their natural projections.") | |
4907 | (license license:gpl3))) | |
1a24f855 RW |
4908 | |
4909 | (define-public r-birta | |
4910 | (package | |
4911 | (name "r-birta") | |
4912 | (version "1.28.0") | |
4913 | (source | |
4914 | (origin | |
4915 | (method url-fetch) | |
4916 | (uri (bioconductor-uri "birta" version)) | |
4917 | (sha256 | |
4918 | (base32 | |
4919 | "12xjyvgmh4h0b7hi4qg50kcpb9003gnh2xyfgncb8l9mzvsbkxc2")))) | |
4920 | (build-system r-build-system) | |
4921 | (propagated-inputs | |
4922 | `(("r-biobase" ,r-biobase) | |
4923 | ("r-limma" ,r-limma) | |
4924 | ("r-mass" ,r-mass))) | |
4925 | (home-page "https://bioconductor.org/packages/birta") | |
4926 | (synopsis "Bayesian inference of regulation of transcriptional activity") | |
4927 | (description | |
4928 | "Expression levels of mRNA molecules are regulated by different | |
4929 | processes, comprising inhibition or activation by transcription factors and | |
4930 | post-transcriptional degradation by microRNAs. @dfn{birta} (Bayesian | |
4931 | Inference of Regulation of Transcriptional Activity) uses the regulatory | |
4932 | networks of transcription factors and miRNAs together with mRNA and miRNA | |
4933 | expression data to predict switches in regulatory activity between two | |
4934 | conditions. A Bayesian network is used to model the regulatory structure and | |
4935 | Markov-Chain-Monte-Carlo is applied to sample the activity states.") | |
4936 | (license license:gpl2+))) | |
a9fac3f4 RW |
4937 | |
4938 | (define-public r-ropls | |
4939 | (package | |
4940 | (name "r-ropls") | |
4941 | (version "1.16.0") | |
4942 | (source | |
4943 | (origin | |
4944 | (method url-fetch) | |
4945 | (uri (bioconductor-uri "ropls" version)) | |
4946 | (sha256 | |
4947 | (base32 | |
4948 | "099nv9dgmw3avkxv7cd27r16yj56svjlp5q4i389yp1n0r5zhyl2")))) | |
4949 | (build-system r-build-system) | |
4950 | (propagated-inputs `(("r-biobase" ,r-biobase))) | |
4951 | (native-inputs | |
4952 | `(("r-knitr" ,r-knitr))) ; for vignettes | |
4953 | (home-page "https://dx.doi.org/10.1021/acs.jproteome.5b00354") | |
4954 | (synopsis "Multivariate analysis and feature selection of omics data") | |
4955 | (description | |
4956 | "Latent variable modeling with @dfn{Principal Component Analysis} (PCA) | |
4957 | and @dfn{Partial Least Squares} (PLS) are powerful methods for visualization, | |
4958 | regression, classification, and feature selection of omics data where the | |
4959 | number of variables exceeds the number of samples and with multicollinearity | |
4960 | among variables. @dfn{Orthogonal Partial Least Squares} (OPLS) enables to | |
4961 | separately model the variation correlated (predictive) to the factor of | |
4962 | interest and the uncorrelated (orthogonal) variation. While performing | |
4963 | similarly to PLS, OPLS facilitates interpretation. | |
4964 | ||
4965 | This package provides imlementations of PCA, PLS, and OPLS for multivariate | |
4966 | analysis and feature selection of omics data. In addition to scores, loadings | |
4967 | and weights plots, the package provides metrics and graphics to determine the | |
4968 | optimal number of components (e.g. with the R2 and Q2 coefficients), check the | |
4969 | validity of the model by permutation testing, detect outliers, and perform | |
4970 | feature selection (e.g. with Variable Importance in Projection or regression | |
4971 | coefficients).") | |
4972 | (license license:cecill))) | |
075a9094 RW |
4973 | |
4974 | (define-public r-biosigner | |
4975 | (package | |
4976 | (name "r-biosigner") | |
4977 | (version "1.12.0") | |
4978 | (source | |
4979 | (origin | |
4980 | (method url-fetch) | |
4981 | (uri (bioconductor-uri "biosigner" version)) | |
4982 | (sha256 | |
4983 | (base32 | |
4984 | "1643iya40v6whb7lw7y34w5sanbasvj4yhvcygbip667yhphyv5b")))) | |
4985 | (build-system r-build-system) | |
4986 | (propagated-inputs | |
4987 | `(("r-biobase" ,r-biobase) | |
4988 | ("r-e1071" ,r-e1071) | |
4989 | ("r-randomforest" ,r-randomforest) | |
4990 | ("r-ropls" ,r-ropls))) | |
4991 | (native-inputs | |
4992 | `(("r-knitr" ,r-knitr) | |
4993 | ("r-rmarkdown" ,r-rmarkdown) | |
4994 | ("pandoc" ,ghc-pandoc) | |
4995 | ("pandoc-citeproc" ,ghc-pandoc-citeproc))) ; all for vignettes | |
4996 | (home-page "https://bioconductor.org/packages/biosigner/") | |
4997 | (synopsis "Signature discovery from omics data") | |
4998 | (description | |
4999 | "Feature selection is critical in omics data analysis to extract | |
5000 | restricted and meaningful molecular signatures from complex and high-dimension | |
5001 | data, and to build robust classifiers. This package implements a method to | |
5002 | assess the relevance of the variables for the prediction performances of the | |
5003 | classifier. The approach can be run in parallel with the PLS-DA, Random | |
5004 | Forest, and SVM binary classifiers. The signatures and the corresponding | |
5005 | 'restricted' models are returned, enabling future predictions on new | |
5006 | datasets.") | |
5007 | (license license:cecill))) | |
ae6fa185 RW |
5008 | |
5009 | (define-public r-annotatr | |
5010 | (package | |
5011 | (name "r-annotatr") | |
5012 | (version "1.10.0") | |
5013 | (source | |
5014 | (origin | |
5015 | (method url-fetch) | |
5016 | (uri (bioconductor-uri "annotatr" version)) | |
5017 | (sha256 | |
5018 | (base32 | |
5019 | "1zlhy6swfgqjhhcqn8c6akxd4c4z8p85swfh095imji7hxnlhh1f")))) | |
5020 | (build-system r-build-system) | |
5021 | (propagated-inputs | |
5022 | `(("r-annotationdbi" ,r-annotationdbi) | |
5023 | ("r-annotationhub" ,r-annotationhub) | |
5024 | ("r-dplyr" ,r-dplyr) | |
5025 | ("r-genomeinfodb" ,r-genomeinfodb) | |
5026 | ("r-genomicfeatures" ,r-genomicfeatures) | |
5027 | ("r-genomicranges" ,r-genomicranges) | |
5028 | ("r-ggplot2" ,r-ggplot2) | |
5029 | ("r-iranges" ,r-iranges) | |
5030 | ("r-readr" ,r-readr) | |
5031 | ("r-regioner" ,r-regioner) | |
5032 | ("r-reshape2" ,r-reshape2) | |
5033 | ("r-rtracklayer" ,r-rtracklayer) | |
5034 | ("r-s4vectors" ,r-s4vectors))) | |
5035 | (home-page "https://bioconductor.org/packages/annotatr/") | |
5036 | (synopsis "Annotation of genomic regions to genomic annotations") | |
5037 | (description | |
5038 | "Given a set of genomic sites/regions (e.g. ChIP-seq peaks, CpGs, | |
5039 | differentially methylated CpGs or regions, SNPs, etc.) it is often of interest | |
5040 | to investigate the intersecting genomic annotations. Such annotations include | |
5041 | those relating to gene models (promoters, 5'UTRs, exons, introns, and 3'UTRs), | |
5042 | CpGs (CpG islands, CpG shores, CpG shelves), or regulatory sequences such as | |
5043 | enhancers. The annotatr package provides an easy way to summarize and | |
5044 | visualize the intersection of genomic sites/regions with genomic | |
5045 | annotations.") | |
5046 | (license license:gpl3))) | |
2cb738a6 RW |
5047 | |
5048 | (define-public r-rsubread | |
5049 | (package | |
5050 | (name "r-rsubread") | |
f791b1ee | 5051 | (version "1.34.7") |
2cb738a6 RW |
5052 | (source |
5053 | (origin | |
5054 | (method url-fetch) | |
5055 | (uri (bioconductor-uri "Rsubread" version)) | |
5056 | (sha256 | |
5057 | (base32 | |
f791b1ee | 5058 | "0z4ydk9296bp76ah5y6a7za5jyn4h238xngb789zragly902x83y")))) |
2cb738a6 RW |
5059 | (properties `((upstream-name . "Rsubread"))) |
5060 | (build-system r-build-system) | |
5061 | (inputs `(("zlib" ,zlib))) | |
5062 | (home-page "https://bioconductor.org/packages/Rsubread/") | |
5063 | (synopsis "Subread sequence alignment and counting for R") | |
5064 | (description | |
5065 | "This package provides tools for alignment, quantification and analysis | |
5066 | of second and third generation sequencing data. It includes functionality for | |
5067 | read mapping, read counting, SNP calling, structural variant detection and | |
5068 | gene fusion discovery. It can be applied to all major sequencing techologies | |
5069 | and to both short and long sequence reads.") | |
5070 | (license license:gpl3))) | |
a6fedf1f | 5071 | |
a0422d18 | 5072 | (define-public r-flowutils |
5073 | (package | |
5074 | (name "r-flowutils") | |
5075 | (version "1.48.0") | |
5076 | (source | |
5077 | (origin | |
5078 | (method url-fetch) | |
5079 | (uri (bioconductor-uri "flowUtils" version)) | |
5080 | (sha256 | |
5081 | (base32 | |
5082 | "1r7b0rszdzjq7jphh65p5m4x5ps0zbbagxl26gn2mapbjdyb47rm")))) | |
5083 | (properties `((upstream-name . "flowUtils"))) | |
5084 | (build-system r-build-system) | |
5085 | (propagated-inputs | |
5086 | `(("r-biobase" ,r-biobase) | |
5087 | ("r-corpcor" ,r-corpcor) | |
5088 | ("r-flowcore" ,r-flowcore) | |
5089 | ("r-graph" ,r-graph) | |
5090 | ("r-runit" ,r-runit) | |
5091 | ("r-xml" ,r-xml))) | |
5092 | (home-page "https://github.com/jspidlen/flowUtils") | |
5093 | (synopsis "Utilities for flow cytometry") | |
5094 | (description | |
5095 | "This package provides utilities for flow cytometry data.") | |
5096 | (license license:artistic2.0))) | |
5097 | ||
ed6f49fc | 5098 | (define-public r-consensusclusterplus |
5099 | (package | |
5100 | (name "r-consensusclusterplus") | |
5101 | (version "1.48.0") | |
5102 | (source | |
5103 | (origin | |
5104 | (method url-fetch) | |
5105 | (uri (bioconductor-uri "ConsensusClusterPlus" version)) | |
5106 | (sha256 | |
5107 | (base32 | |
5108 | "1mlcm3wq5n8s0gxs35j0ph9576fhbrbrrsj2xy84fy20prcfs4w8")))) | |
5109 | (properties | |
5110 | `((upstream-name . "ConsensusClusterPlus"))) | |
5111 | (build-system r-build-system) | |
5112 | (propagated-inputs | |
5113 | `(("r-all" ,r-all) | |
5114 | ("r-biobase" ,r-biobase) | |
5115 | ("r-cluster" ,r-cluster))) | |
5116 | (home-page "https://bioconductor.org/packages/ConsensusClusterPlus") | |
5117 | (synopsis "Clustering algorithm") | |
5118 | (description | |
5119 | "This package provides an implementation of an algorithm for determining | |
5120 | cluster count and membership by stability evidence in unsupervised analysis.") | |
5121 | (license license:gpl2))) | |
5122 | ||
a6fedf1f | 5123 | (define-public r-flowcore |
5124 | (package | |
5125 | (name "r-flowcore") | |
5126 | (version "1.50.0") | |
5127 | (source | |
5128 | (origin | |
5129 | (method url-fetch) | |
5130 | (uri (bioconductor-uri "flowCore" version)) | |
5131 | (sha256 | |
5132 | (base32 | |
5133 | "0pvcyzycsmgc8iw60q9xnhllfan6ihwpz3gvk8h1n9jmhpxzylan")))) | |
5134 | (properties `((upstream-name . "flowCore"))) | |
5135 | (build-system r-build-system) | |
5136 | (propagated-inputs | |
5137 | `(("r-bh" ,r-bh) | |
5138 | ("r-biobase" ,r-biobase) | |
5139 | ("r-biocgenerics" ,r-biocgenerics) | |
5140 | ("r-corpcor" ,r-corpcor) | |
5141 | ("r-graph" ,r-graph) | |
5142 | ("r-mass" ,r-mass) | |
5143 | ("r-matrixstats" ,r-matrixstats) | |
5144 | ("r-rcpp" ,r-rcpp) | |
5145 | ("r-rrcov" ,r-rrcov))) | |
5146 | (home-page "https://bioconductor.org/packages/flowCore") | |
5147 | (synopsis "Basic structures for flow cytometry data") | |
5148 | (description | |
5149 | "This package provides S4 data structures and basic functions to deal | |
5150 | with flow cytometry data.") | |
5151 | (license license:artistic2.0))) | |
e0cb053e | 5152 | |
5153 | (define-public r-flowmeans | |
5154 | (package | |
5155 | (name "r-flowmeans") | |
5156 | (version "1.44.0") | |
5157 | (source | |
5158 | (origin | |
5159 | (method url-fetch) | |
5160 | (uri (bioconductor-uri "flowMeans" version)) | |
5161 | (sha256 | |
5162 | (base32 | |
5163 | "0yp6y3mq5h4nf1d7ybqnriigwfmwanrqavpj3ry482sgiaip1hp2")))) | |
5164 | (properties `((upstream-name . "flowMeans"))) | |
5165 | (build-system r-build-system) | |
5166 | (propagated-inputs | |
5167 | `(("r-biobase" ,r-biobase) | |
5168 | ("r-feature" ,r-feature) | |
5169 | ("r-flowcore" ,r-flowcore) | |
5170 | ("r-rrcov" ,r-rrcov))) | |
5171 | (home-page "https://bioconductor.org/packages/flowMeans") | |
5172 | (synopsis "Non-parametric flow cytometry data gating") | |
5173 | (description | |
5174 | "This package provides tools to identify cell populations in Flow | |
5175 | Cytometry data using non-parametric clustering and segmented-regression-based | |
5176 | change point detection.") | |
5177 | (license license:artistic2.0))) | |
1502751b | 5178 | |
5179 | (define-public r-flowsom | |
5180 | (package | |
5181 | (name "r-flowsom") | |
5182 | (version "1.16.0") | |
5183 | (source | |
5184 | (origin | |
5185 | (method url-fetch) | |
5186 | (uri (bioconductor-uri "FlowSOM" version)) | |
5187 | (sha256 | |
5188 | (base32 | |
5189 | "03wl3xk7g7vajc4kkrqa0gsbjfxlqr918qi849h5nir31963398l")))) | |
5190 | (properties `((upstream-name . "FlowSOM"))) | |
5191 | (build-system r-build-system) | |
5192 | (propagated-inputs | |
5193 | `(("r-biocgenerics" ,r-biocgenerics) | |
5194 | ("r-consensusclusterplus" ,r-consensusclusterplus) | |
5195 | ("r-flowcore" ,r-flowcore) | |
5196 | ("r-flowutils" ,r-flowutils) | |
5197 | ("r-igraph" ,r-igraph) | |
5198 | ("r-tsne" ,r-tsne) | |
5199 | ("r-xml" ,r-xml))) | |
5200 | (home-page "https://bioconductor.org/packages/FlowSOM/") | |
5201 | (synopsis "Visualize and interpret cytometry data") | |
5202 | (description | |
5203 | "FlowSOM offers visualization options for cytometry data, by using | |
5204 | self-organizing map clustering and minimal spanning trees.") | |
5205 | (license license:gpl2+))) | |
1adb9cbc | 5206 | |
5207 | (define-public r-mixomics | |
5208 | (package | |
5209 | (name "r-mixomics") | |
11f973e0 | 5210 | (version "6.8.4") |
1adb9cbc | 5211 | (source |
5212 | (origin | |
5213 | (method url-fetch) | |
5214 | (uri (bioconductor-uri "mixOmics" version)) | |
5215 | (sha256 | |
5216 | (base32 | |
11f973e0 | 5217 | "0lw4c9lxcm83xrvl4y120i1z710qjbdqginhrw738azpr1f82hcg")))) |
1adb9cbc | 5218 | (properties `((upstream-name . "mixOmics"))) |
5219 | (build-system r-build-system) | |
5220 | (propagated-inputs | |
5221 | `(("r-corpcor" ,r-corpcor) | |
5222 | ("r-dplyr" ,r-dplyr) | |
5223 | ("r-ellipse" ,r-ellipse) | |
5224 | ("r-ggplot2" ,r-ggplot2) | |
5225 | ("r-gridextra" ,r-gridextra) | |
5226 | ("r-igraph" ,r-igraph) | |
5227 | ("r-lattice" ,r-lattice) | |
5228 | ("r-mass" ,r-mass) | |
5229 | ("r-matrixstats" ,r-matrixstats) | |
5230 | ("r-rarpack" ,r-rarpack) | |
5231 | ("r-rcolorbrewer" ,r-rcolorbrewer) | |
5232 | ("r-reshape2" ,r-reshape2) | |
5233 | ("r-tidyr" ,r-tidyr))) | |
5234 | (home-page "http://www.mixOmics.org") | |
5235 | (synopsis "Multivariate methods for exploration of biological datasets") | |
5236 | (description | |
5237 | "mixOmics offers a wide range of multivariate methods for the exploration | |
5238 | and integration of biological datasets with a particular focus on variable | |
5239 | selection. The package proposes several sparse multivariate models we have | |
5240 | developed to identify the key variables that are highly correlated, and/or | |
5241 | explain the biological outcome of interest. The data that can be analysed | |
5242 | with mixOmics may come from high throughput sequencing technologies, such as | |
5243 | omics data (transcriptomics, metabolomics, proteomics, metagenomics etc) but | |
5244 | also beyond the realm of omics (e.g. spectral imaging). The methods | |
5245 | implemented in mixOmics can also handle missing values without having to | |
5246 | delete entire rows with missing data.") | |
5247 | (license license:gpl2+))) | |
a0efa069 | 5248 | |
5249 | (define-public r-depecher | |
5250 | (package | |
5251 | (name "r-depecher") | |
5252 | (version "1.0.3") | |
5253 | (source | |
5254 | (origin | |
5255 | (method url-fetch) | |
5256 | (uri (bioconductor-uri "DepecheR" version)) | |
5257 | (sha256 | |
5258 | (base32 | |
5259 | "0qj2h2a50fncppvi2phh0mbivxkn1mv702mqpi9mvvkf3bzq8m0h")))) | |
5260 | (properties `((upstream-name . "DepecheR"))) | |
5261 | (build-system r-build-system) | |
5262 | (arguments | |
5263 | `(#:phases | |
5264 | (modify-phases %standard-phases | |
5265 | (add-after 'unpack 'fix-syntax-error | |
5266 | (lambda _ | |
5267 | (substitute* "src/Makevars" | |
5268 | ((" & ") " && ")) | |
5269 | #t))))) | |
5270 | (propagated-inputs | |
5271 | `(("r-beanplot" ,r-beanplot) | |
5272 | ("r-biocparallel" ,r-biocparallel) | |
5273 | ("r-dosnow" ,r-dosnow) | |
5274 | ("r-dplyr" ,r-dplyr) | |
5275 | ("r-foreach" ,r-foreach) | |
5276 | ("r-ggplot2" ,r-ggplot2) | |
5277 | ("r-gplots" ,r-gplots) | |
5278 | ("r-mass" ,r-mass) | |
5279 | ("r-matrixstats" ,r-matrixstats) | |
5280 | ("r-mixomics" ,r-mixomics) | |
5281 | ("r-moments" ,r-moments) | |
5282 | ("r-rcpp" ,r-rcpp) | |
5283 | ("r-rcppeigen" ,r-rcppeigen) | |
5284 | ("r-reshape2" ,r-reshape2) | |
5285 | ("r-viridis" ,r-viridis))) | |
5286 | (home-page "https://bioconductor.org/packages/DepecheR/") | |
5287 | (synopsis "Identify traits of clusters in high-dimensional entities") | |
5288 | (description | |
5289 | "The purpose of this package is to identify traits in a dataset that can | |
5290 | separate groups. This is done on two levels. First, clustering is performed, | |
5291 | using an implementation of sparse K-means. Secondly, the generated clusters | |
5292 | are used to predict outcomes of groups of individuals based on their | |
5293 | distribution of observations in the different clusters. As certain clusters | |
5294 | with separating information will be identified, and these clusters are defined | |
5295 | by a sparse number of variables, this method can reduce the complexity of | |
5296 | data, to only emphasize the data that actually matters.") | |
5297 | (license license:expat))) | |
b46a0ee7 | 5298 | |
bb88417f RW |
5299 | (define-public r-rcistarget |
5300 | (package | |
5301 | (name "r-rcistarget") | |
5302 | (version "1.4.0") | |
5303 | (source | |
5304 | (origin | |
5305 | (method url-fetch) | |
5306 | (uri (bioconductor-uri "RcisTarget" version)) | |
5307 | (sha256 | |
5308 | (base32 | |
5309 | "133x2vr86ifbk82q08x1c8q19zsk5za7b6qrzz77dhsyf4bhcvpd")))) | |
5310 | (properties `((upstream-name . "RcisTarget"))) | |
5311 | (build-system r-build-system) | |
5312 | (propagated-inputs | |
5313 | `(("r-aucell" ,r-aucell) | |
5314 | ("r-biocgenerics" ,r-biocgenerics) | |
5315 | ("r-data-table" ,r-data-table) | |
5316 | ("r-feather" ,r-feather) | |
5317 | ("r-gseabase" ,r-gseabase) | |
5318 | ("r-r-utils" ,r-r-utils) | |
5319 | ("r-summarizedexperiment" ,r-summarizedexperiment))) | |
5320 | (home-page "https://aertslab.org/#scenic") | |
5321 | (synopsis "Identify transcription factor binding motifs enriched on a gene list") | |
5322 | (description | |
5323 | "RcisTarget identifies @dfn{transcription factor binding motifs} (TFBS) | |
5324 | over-represented on a gene list. In a first step, RcisTarget selects DNA | |
5325 | motifs that are significantly over-represented in the surroundings of the | |
5326 | @dfn{transcription start site} (TSS) of the genes in the gene-set. This is | |
5327 | achieved by using a database that contains genome-wide cross-species rankings | |
5328 | for each motif. The motifs that are then annotated to TFs and those that have | |
5329 | a high @dfn{Normalized Enrichment Score} (NES) are retained. Finally, for | |
5330 | each motif and gene-set, RcisTarget predicts the candidate target genes (i.e. | |
5331 | genes in the gene-set that are ranked above the leading edge).") | |
5332 | (license license:gpl3))) | |
5333 | ||
b46a0ee7 RW |
5334 | (define-public r-cicero |
5335 | (package | |
5336 | (name "r-cicero") | |
5337 | (version "1.2.0") | |
5338 | (source | |
5339 | (origin | |
5340 | (method url-fetch) | |
5341 | (uri (bioconductor-uri "cicero" version)) | |
5342 | (sha256 | |
5343 | (base32 | |
5344 | "0f15l8zrh7l7nnvznb66116hvfk15djb9q240vbscm2w0y5fvkcr")))) | |
5345 | (build-system r-build-system) | |
5346 | (propagated-inputs | |
5347 | `(("r-assertthat" ,r-assertthat) | |
5348 | ("r-biobase" ,r-biobase) | |
5349 | ("r-biocgenerics" ,r-biocgenerics) | |
5350 | ("r-data-table" ,r-data-table) | |
5351 | ("r-dplyr" ,r-dplyr) | |
5352 | ("r-fnn" ,r-fnn) | |
5353 | ("r-genomicranges" ,r-genomicranges) | |
5354 | ("r-ggplot2" ,r-ggplot2) | |
5355 | ("r-glasso" ,r-glasso) | |
5356 | ("r-gviz" ,r-gviz) | |
5357 | ("r-igraph" ,r-igraph) | |
5358 | ("r-iranges" ,r-iranges) | |
5359 | ("r-matrix" ,r-matrix) | |
5360 | ("r-monocle" ,r-monocle) | |
5361 | ("r-plyr" ,r-plyr) | |
5362 | ("r-reshape2" ,r-reshape2) | |
5363 | ("r-s4vectors" ,r-s4vectors) | |
5364 | ("r-stringr" ,r-stringr) | |
5365 | ("r-tibble" ,r-tibble) | |
5366 | ("r-vgam" ,r-vgam))) | |
5367 | (home-page "https://bioconductor.org/packages/cicero/") | |
5368 | (synopsis "Predict cis-co-accessibility from single-cell data") | |
5369 | (description | |
5370 | "Cicero computes putative cis-regulatory maps from single-cell chromatin | |
5371 | accessibility data. It also extends the monocle package for use in chromatin | |
5372 | accessibility data.") | |
5373 | (license license:expat))) | |
14bb1c48 RW |
5374 | |
5375 | ;; This is the latest commit on the "monocle3" branch. | |
5376 | (define-public r-cicero-monocle3 | |
5377 | (let ((commit "fa2fb6515857a8cfc88bc9af044f34de1bcd2b7b") | |
5378 | (revision "1")) | |
5379 | (package (inherit r-cicero) | |
5380 | (name "r-cicero-monocle3") | |
5381 | (version (git-version "1.3.2" revision commit)) | |
5382 | (source | |
5383 | (origin | |
5384 | (method git-fetch) | |
5385 | (uri (git-reference | |
5386 | (url "https://github.com/cole-trapnell-lab/cicero-release.git") | |
5387 | (commit commit))) | |
5388 | (file-name (git-file-name name version)) | |
5389 | (sha256 | |
5390 | (base32 | |
5391 | "077yza93wdhi08n40md20jwk55k9lw1f3y0063qkk90cpz60wi0c")))) | |
5392 | (propagated-inputs | |
5393 | `(("r-monocle3" ,r-monocle3) | |
5394 | ,@(alist-delete "r-monocle" | |
5395 | (package-propagated-inputs r-cicero))))))) | |
a9815a6c RW |
5396 | |
5397 | (define-public r-cistopic | |
5398 | (let ((commit "29abd8df9afb60ff27ac3f0a590930debe926950") | |
5399 | (revision "0")) | |
5400 | (package | |
5401 | (name "r-cistopic") | |
5402 | (version (git-version "0.2.1" revision commit)) | |
5403 | (source | |
5404 | (origin | |
5405 | (method git-fetch) | |
5406 | (uri (git-reference | |
5407 | (url "https://github.com/aertslab/cisTopic.git") | |
5408 | (commit commit))) | |
5409 | (file-name (git-file-name name version)) | |
5410 | (sha256 | |
5411 | (base32 | |
5412 | "0s8irpsv5d2zcv4ihanvsf1vrpignzliscxnvs4519af3jmx78h8")))) | |
5413 | (build-system r-build-system) | |
5414 | (propagated-inputs | |
5415 | `(("r-aucell" ,r-aucell) | |
5416 | ("r-data-table" ,r-data-table) | |
5417 | ("r-dplyr" ,r-dplyr) | |
5418 | ("r-dosnow" ,r-dosnow) | |
5419 | ("r-dt" ,r-dt) | |
5420 | ("r-feather" ,r-feather) | |
5421 | ("r-fitdistrplus" ,r-fitdistrplus) | |
5422 | ("r-genomicranges" ,r-genomicranges) | |
5423 | ("r-ggplot2" ,r-ggplot2) | |
5424 | ("r-lda" ,r-lda) | |
5425 | ("r-matrix" ,r-matrix) | |
5426 | ("r-plyr" ,r-plyr) | |
5427 | ("r-rcistarget" ,r-rcistarget) | |
5428 | ("r-rtracklayer" ,r-rtracklayer) | |
5429 | ("r-s4vectors" ,r-s4vectors))) | |
5430 | (home-page "https://github.com/aertslab/cisTopic") | |
5431 | (synopsis "Modelling of cis-regulatory topics from single cell epigenomics data") | |
5432 | (description | |
5433 | "The sparse nature of single cell epigenomics data can be overruled using | |
5434 | probabilistic modelling methods such as @dfn{Latent Dirichlet | |
5435 | Allocation} (LDA). This package allows the probabilistic modelling of | |
5436 | cis-regulatory topics (cisTopics) from single cell epigenomics data, and | |
5437 | includes functionalities to identify cell states based on the contribution of | |
5438 | cisTopics and explore the nature and regulatory proteins driving them.") | |
5439 | (license license:gpl3)))) | |
d85c0f98 RW |
5440 | |
5441 | (define-public r-genie3 | |
5442 | (package | |
5443 | (name "r-genie3") | |
5444 | (version "1.6.0") | |
5445 | (source | |
5446 | (origin | |
5447 | (method url-fetch) | |
5448 | (uri (bioconductor-uri "GENIE3" version)) | |
5449 | (sha256 | |
5450 | (base32 | |
5451 | "0lvrpw4xn7xyinmn13f65i0vkzfzwdj5y8gsa8vyy8kcn83d28fx")))) | |
5452 | (properties `((upstream-name . "GENIE3"))) | |
5453 | (build-system r-build-system) | |
5454 | (propagated-inputs `(("r-reshape2" ,r-reshape2))) | |
5455 | (home-page "https://bioconductor.org/packages/GENIE3") | |
5456 | (synopsis "Gene network inference with ensemble of trees") | |
5457 | (description | |
5458 | "This package implements the GENIE3 algorithm for inferring gene | |
5459 | regulatory networks from expression data.") | |
5460 | (license license:gpl2+))) | |
db316d73 RW |
5461 | |
5462 | (define-public r-roc | |
5463 | (package | |
5464 | (name "r-roc") | |
5465 | (version "1.60.0") | |
5466 | (source | |
5467 | (origin | |
5468 | (method url-fetch) | |
5469 | (uri (bioconductor-uri "ROC" version)) | |
5470 | (sha256 | |
5471 | (base32 | |
5472 | "1sapnl8kyaldgvdc657wqcmyjb24nvrnaw7v94bbs8yf5pmfm71c")))) | |
5473 | (properties `((upstream-name . "ROC"))) | |
5474 | (build-system r-build-system) | |
5475 | (home-page "https://www.bioconductor.org/packages/ROC/") | |
5476 | (synopsis "Utilities for ROC curves") | |
5477 | (description | |
5478 | "This package provides utilities for @dfn{Receiver Operating | |
5479 | Characteristic} (ROC) curves, with a focus on micro arrays.") | |
5480 | (license license:artistic2.0))) | |
46721dea RW |
5481 | |
5482 | (define-public r-illuminahumanmethylation450kanno-ilmn12-hg19 | |
5483 | (package | |
5484 | (name "r-illuminahumanmethylation450kanno-ilmn12-hg19") | |
5485 | (version "0.6.0") | |
5486 | (source | |
5487 | (origin | |
5488 | (method url-fetch) | |
5489 | (uri (bioconductor-uri | |
5490 | "IlluminaHumanMethylation450kanno.ilmn12.hg19" | |
5491 | version 'annotation)) | |
5492 | (sha256 | |
5493 | (base32 | |
5494 | "059vlxsx3p3fcnywwirahsc6mlk813zpqnbv0jsrag6x5bb8z6r4")))) | |
5495 | (properties | |
5496 | `((upstream-name | |
5497 | . "IlluminaHumanMethylation450kanno.ilmn12.hg19"))) | |
5498 | (build-system r-build-system) | |
5499 | (propagated-inputs `(("r-minfi" ,r-minfi))) | |
5500 | (home-page | |
5501 | "https://bioconductor.org/packages/IlluminaHumanMethylation450kanno.ilmn12.hg19/") | |
5502 | (synopsis "Annotation for Illumina's 450k methylation arrays") | |
5503 | (description | |
5504 | "This package provides manifests and annotation for Illumina's 450k array | |
5505 | data.") | |
5506 | (license license:artistic2.0))) | |
38babeaa RW |
5507 | |
5508 | (define-public r-watermelon | |
5509 | (package | |
5510 | (name "r-watermelon") | |
5511 | (version "1.28.0") | |
5512 | (source | |
5513 | (origin | |
5514 | (method url-fetch) | |
5515 | (uri (bioconductor-uri "wateRmelon" version)) | |
5516 | (sha256 | |
5517 | (base32 | |
5518 | "0354ahmfvhqw3yfp17rmz35vlgjp262n4q3hr8qyccyrnk2dz17z")))) | |
5519 | (properties `((upstream-name . "wateRmelon"))) | |
5520 | (build-system r-build-system) | |
5521 | (propagated-inputs | |
5522 | `(("r-biobase" ,r-biobase) | |
5523 | ("r-illuminahumanmethylation450kanno-ilmn12-hg19" | |
5524 | ,r-illuminahumanmethylation450kanno-ilmn12-hg19) | |
5525 | ("r-illuminaio" ,r-illuminaio) | |
5526 | ("r-limma" ,r-limma) | |
5527 | ("r-lumi" ,r-lumi) | |
5528 | ("r-matrixstats" ,r-matrixstats) | |
5529 | ("r-methylumi" ,r-methylumi) | |
5530 | ("r-roc" ,r-roc))) | |
5531 | (home-page "https://bioconductor.org/packages/wateRmelon/") | |
5532 | (synopsis "Illumina 450 methylation array normalization and metrics") | |
5533 | (description | |
5534 | "The standard index of DNA methylation (beta) is computed from methylated | |
5535 | and unmethylated signal intensities. Betas calculated from raw signal | |
5536 | intensities perform well, but using 11 methylomic datasets we demonstrate that | |
5537 | quantile normalization methods produce marked improvement. The commonly used | |
5538 | procedure of normalizing betas is inferior to the separate normalization of M | |
5539 | and U, and it is also advantageous to normalize Type I and Type II assays | |
5540 | separately. This package provides 15 flavours of betas and three performance | |
5541 | metrics, with methods for objects produced by the @code{methylumi} and | |
5542 | @code{minfi} packages.") | |
5543 | (license license:gpl3))) | |
7d2cb646 RW |
5544 | |
5545 | (define-public r-gdsfmt | |
5546 | (package | |
5547 | (name "r-gdsfmt") | |
5548 | (version "1.20.0") | |
5549 | (source | |
5550 | (origin | |
5551 | (method url-fetch) | |
5552 | (uri (bioconductor-uri "gdsfmt" version)) | |
5553 | (sha256 | |
5554 | (base32 | |
5555 | "0h3hgwxq26dg09fyxqg545v9dg1dizsj58cf05rncr3jj4f8g0xy")) | |
5556 | (modules '((guix build utils))) | |
5557 | ;; Remove bundled sources of zlib, lz4, and xz. Don't attempt to build | |
5558 | ;; them and link with system libraries instead. | |
5559 | (snippet | |
5560 | '(begin | |
5561 | (for-each delete-file-recursively | |
5562 | '("src/LZ4" | |
5563 | "src/XZ" | |
5564 | "src/ZLIB")) | |
5565 | (substitute* "src/Makevars" | |
5566 | (("all: \\$\\(SHLIB\\)") "all:") | |
5567 | (("\\$\\(SHLIB\\): liblzma.a") "") | |
5568 | (("(ZLIB|LZ4)/.*") "") | |
5569 | (("CoreArray/dVLIntGDS.cpp.*") | |
5570 | "CoreArray/dVLIntGDS.cpp") | |
5571 | (("CoreArray/dVLIntGDS.o.*") | |
5572 | "CoreArray/dVLIntGDS.o") | |
5573 | (("PKG_LIBS = ./liblzma.a") | |
5574 | "PKG_LIBS = -llz4")) | |
5575 | (substitute* "src/CoreArray/dStream.h" | |
5576 | (("include \"../(ZLIB|LZ4|XZ/api)/(.*)\"" _ _ header) | |
5577 | (string-append "include <" header ">"))) | |
5578 | #t)))) | |
5579 | (properties `((upstream-name . "gdsfmt"))) | |
5580 | (build-system r-build-system) | |
5581 | (inputs | |
5582 | `(("lz4" ,lz4) | |
5583 | ("xz" ,xz) | |
5584 | ("zlib" ,zlib))) | |
5585 | (home-page "http://corearray.sourceforge.net/") | |
5586 | (synopsis | |
5587 | "R Interface to CoreArray Genomic Data Structure (GDS) Files") | |
5588 | (description | |
5589 | "This package provides a high-level R interface to CoreArray @dfn{Genomic | |
5590 | Data Structure} (GDS) data files, which are portable across platforms with | |
5591 | hierarchical structure to store multiple scalable array-oriented data sets | |
5592 | with metadata information. It is suited for large-scale datasets, especially | |
5593 | for data which are much larger than the available random-access memory. The | |
5594 | @code{gdsfmt} package offers efficient operations specifically designed for | |
5595 | integers of less than 8 bits, since a diploid genotype, like | |
5596 | @dfn{single-nucleotide polymorphism} (SNP), usually occupies fewer bits than a | |
5597 | byte. Data compression and decompression are available with relatively | |
5598 | efficient random access. It is also allowed to read a GDS file in parallel | |
5599 | with multiple R processes supported by the package @code{parallel}.") | |
5600 | (license license:lgpl3))) | |
6b5f59c7 RW |
5601 | |
5602 | (define-public r-bigmelon | |
5603 | (package | |
5604 | (name "r-bigmelon") | |
5605 | (version "1.10.0") | |
5606 | (source | |
5607 | (origin | |
5608 | (method url-fetch) | |
5609 | (uri (bioconductor-uri "bigmelon" version)) | |
5610 | (sha256 | |
5611 | (base32 | |
5612 | "0269kf3d34dbng3swk7pclpk02vy4k3askygmzi5my3fqyfzdkj9")))) | |
5613 | (properties `((upstream-name . "bigmelon"))) | |
5614 | (build-system r-build-system) | |
5615 | (propagated-inputs | |
5616 | `(("r-biobase" ,r-biobase) | |
5617 | ("r-biocgenerics" ,r-biocgenerics) | |
5618 | ("r-gdsfmt" ,r-gdsfmt) | |
5619 | ("r-geoquery" ,r-geoquery) | |
5620 | ("r-methylumi" ,r-methylumi) | |
5621 | ("r-minfi" ,r-minfi) | |
5622 | ("r-watermelon" ,r-watermelon))) | |
5623 | (home-page "https://bioconductor.org/packages/bigmelon/") | |
5624 | (synopsis "Illumina methylation array analysis for large experiments") | |
5625 | (description | |
5626 | "This package provides methods for working with Illumina arrays using the | |
5627 | @code{gdsfmt} package.") | |
5628 | (license license:gpl3))) | |
739b2d10 RW |
5629 | |
5630 | (define-public r-wavcluster | |
5631 | (package | |
5632 | (name "r-wavcluster") | |
5633 | (version "2.18.0") | |
5634 | (source | |
5635 | (origin | |
5636 | (method url-fetch) | |
5637 | (uri (bioconductor-uri "wavClusteR" version)) | |
5638 | (sha256 | |
5639 | (base32 | |
5640 | "02i53dskirzr9nls3dsmv7dqhvy3vikkpx7247zpy2qd9r5yvhy2")))) | |
5641 | (properties `((upstream-name . "wavClusteR"))) | |
5642 | (build-system r-build-system) | |
5643 | (propagated-inputs | |
5644 | `(("r-biocgenerics" ,r-biocgenerics) | |
5645 | ("r-biostrings" ,r-biostrings) | |
5646 | ("r-foreach" ,r-foreach) | |
5647 | ("r-genomicfeatures" ,r-genomicfeatures) | |
5648 | ("r-genomicranges" ,r-genomicranges) | |
5649 | ("r-ggplot2" ,r-ggplot2) | |
5650 | ("r-hmisc" ,r-hmisc) | |
5651 | ("r-iranges" ,r-iranges) | |
5652 | ("r-mclust" ,r-mclust) | |
5653 | ("r-rsamtools" ,r-rsamtools) | |
5654 | ("r-rtracklayer" ,r-rtracklayer) | |
5655 | ("r-s4vectors" ,r-s4vectors) | |
5656 | ("r-seqinr" ,r-seqinr) | |
5657 | ("r-stringr" ,r-stringr) | |
5658 | ("r-wmtsa" ,r-wmtsa))) | |
5659 | (home-page "https://bioconductor.org/packages/wavClusteR/") | |
5660 | (synopsis "Identification of RNA-protein interaction sites in PAR-CLIP data") | |
5661 | (description | |
5662 | "This package provides an integrated pipeline for the analysis of | |
5663 | PAR-CLIP data. PAR-CLIP-induced transitions are first discriminated from | |
5664 | sequencing errors, SNPs and additional non-experimental sources by a non- | |
5665 | parametric mixture model. The protein binding sites (clusters) are then | |
5666 | resolved at high resolution and cluster statistics are estimated using a | |
5667 | rigorous Bayesian framework. Post-processing of the results, data export for | |
5668 | UCSC genome browser visualization and motif search analysis are provided. In | |
5669 | addition, the package allows to integrate RNA-Seq data to estimate the False | |
5670 | Discovery Rate of cluster detection. Key functions support parallel multicore | |
5671 | computing. While wavClusteR was designed for PAR-CLIP data analysis, it can | |
5672 | be applied to the analysis of other NGS data obtained from experimental | |
5673 | procedures that induce nucleotide substitutions (e.g. BisSeq).") | |
5674 | (license license:gpl2))) | |
853211a5 RW |
5675 | |
5676 | (define-public r-timeseriesexperiment | |
5677 | (package | |
5678 | (name "r-timeseriesexperiment") | |
5679 | (version "1.2.0") | |
5680 | (source | |
5681 | (origin | |
5682 | (method url-fetch) | |
5683 | (uri (bioconductor-uri "TimeSeriesExperiment" version)) | |
5684 | (sha256 | |
5685 | (base32 | |
5686 | "1j11g7a2p0yk38fx6wd6152l1xynghj01pfxihalw601jwf1bl0y")))) | |
5687 | (properties | |
5688 | `((upstream-name . "TimeSeriesExperiment"))) | |
5689 | (build-system r-build-system) | |
5690 | (propagated-inputs | |
5691 | `(("r-deseq2" ,r-deseq2) | |
5692 | ("r-dplyr" ,r-dplyr) | |
5693 | ("r-dynamictreecut" ,r-dynamictreecut) | |
5694 | ("r-edger" ,r-edger) | |
5695 | ("r-ggplot2" ,r-ggplot2) | |
5696 | ("r-hmisc" ,r-hmisc) | |
5697 | ("r-limma" ,r-limma) | |
5698 | ("r-magrittr" ,r-magrittr) | |
5699 | ("r-proxy" ,r-proxy) | |
5700 | ("r-s4vectors" ,r-s4vectors) | |
5701 | ("r-summarizedexperiment" ,r-summarizedexperiment) | |
5702 | ("r-tibble" ,r-tibble) | |
5703 | ("r-tidyr" ,r-tidyr) | |
5704 | ("r-vegan" ,r-vegan) | |
5705 | ("r-viridis" ,r-viridis))) | |
5706 | (home-page "https://github.com/nlhuong/TimeSeriesExperiment/") | |
5707 | (synopsis "Analysis for short time-series data") | |
5708 | (description | |
5709 | "This package is a visualization and analysis toolbox for short time | |
5710 | course data which includes dimensionality reduction, clustering, two-sample | |
5711 | differential expression testing and gene ranking techniques. The package also | |
5712 | provides methods for retrieving enriched pathways.") | |
5713 | (license license:lgpl3+))) |