gnu: dealii: Update to 8.5.0.
[jackhill/guix/guix.git] / gnu / packages / bioinformatics.scm
index a9a25c2..c08297d 100644 (file)
@@ -4,7 +4,7 @@
 ;;; Copyright © 2015, 2016 Pjotr Prins <pjotr.guix@thebird.nl>
 ;;; Copyright © 2015 Andreas Enge <andreas@enge.fr>
 ;;; Copyright © 2016 Roel Janssen <roel@gnu.org>
-;;; Copyright © 2016 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2016, 2017 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2016 Marius Bakke <mbakke@fastmail.com>
 ;;; Copyright © 2016 Raoul Bonnal <ilpuccio.febo@gmail.com>
 ;;;
@@ -48,6 +48,7 @@
   #:use-module (gnu packages boost)
   #:use-module (gnu packages compression)
   #:use-module (gnu packages cpio)
+  #:use-module (gnu packages cran)
   #:use-module (gnu packages curl)
   #:use-module (gnu packages documentation)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages xml)
   #:use-module (gnu packages xorg)
   #:use-module (srfi srfi-1)
-  #:use-module (srfi srfi-26))
+  #:use-module (ice-9 match))
 
 (define-public r-ape
   (package
@@ -248,7 +249,7 @@ structure of the predicted RNA.")
        ("python-nose" ,python2-nose)
        ("python-pysam" ,python2-pysam)))
     (inputs
-     `(("htslib" ,htslib)
+     `(("htslib" ,htslib-1.3) ; At least one test fails on htslib-1.4+.
        ("samtools" ,samtools)
        ("bwa" ,bwa)
        ("grep" ,grep)
@@ -300,7 +301,7 @@ BAM files.")
 (define-public bcftools
   (package
     (name "bcftools")
-    (version "1.3.1")
+    (version "1.5")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -308,33 +309,27 @@ BAM files.")
                     version "/bcftools-" version ".tar.bz2"))
               (sha256
                (base32
-                "095ry68vmz9q5s1scjsa698dhgyvgw5aicz24c19iwfbai07mhqj"))
+                "0093hkkvxmbwfaa7905s6185jymynvg42kq6sxv7fili11l5mxwz"))
               (modules '((guix build utils)))
               (snippet
                ;; Delete bundled htslib.
-               '(delete-file-recursively "htslib-1.3.1"))))
+               '(delete-file-recursively "htslib-1.5"))))
     (build-system gnu-build-system)
     (arguments
      `(#:test-target "test"
+       #:configure-flags (list "--with-htslib=system")
        #:make-flags
        (list
         "USE_GPL=1"
+        "LIBS=-lgsl -lgslcblas"
         (string-append "prefix=" (assoc-ref %outputs "out"))
         (string-append "HTSDIR=" (assoc-ref %build-inputs "htslib") "/include")
-        (string-append "HTSLIB=" (assoc-ref %build-inputs "htslib") "/lib/libhts.a")
+        (string-append "HTSLIB=" (assoc-ref %build-inputs "htslib") "/lib/libhts.so")
         (string-append "BGZIP=" (assoc-ref %build-inputs "htslib") "/bin/bgzip")
-        (string-append "TABIX=" (assoc-ref %build-inputs "htslib") "/bin/tabix"))
+        (string-append "TABIX=" (assoc-ref %build-inputs "htslib") "/bin/tabix")
+        (string-append "PACKAGE_VERSION=" ,version))
        #:phases
        (modify-phases %standard-phases
-         (add-after 'unpack 'patch-Makefile
-           (lambda _
-             (substitute* "Makefile"
-               ;; Do not attempt to build htslib.
-               (("^include \\$\\(HTSDIR\\)/htslib\\.mk") "")
-               ;; Link against GSL cblas.
-               (("-lcblas") "-lgslcblas"))
-             #t))
-         (delete 'configure)
          (add-before 'check 'patch-tests
            (lambda _
              (substitute* "test/test.pl"
@@ -956,7 +951,7 @@ package provides command line tools using the Bio++ library.")
 (define-public blast+
   (package
     (name "blast+")
-    (version "2.4.0")
+    (version "2.6.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -964,13 +959,15 @@ package provides command line tools using the Bio++ library.")
                     version "/ncbi-blast-" version "+-src.tar.gz"))
               (sha256
                (base32
-                "14n9jik6vhiwjd3m7bach4xj1pzfn0szbsbyfxybd9l9cc43b6mb"))
+                "15n937pw5aqmyfjb6l387d18grqbb96l63d5xj4l7yyh0zbf2405"))
+              (patches (search-patches "blast+-fix-makefile.patch"))
               (modules '((guix build utils)))
               (snippet
                '(begin
-                  ;; Remove bundled bzip2 and zlib
+                  ;; Remove bundled bzip2, zlib and pcre.
                   (delete-file-recursively "c++/src/util/compress/bzip2")
                   (delete-file-recursively "c++/src/util/compress/zlib")
+                  (delete-file-recursively "c++/src/util/regexp")
                   (substitute* "c++/src/util/compress/Makefile.in"
                     (("bzip2 zlib api") "api"))
                   ;; Remove useless msbuild directory
@@ -979,9 +976,8 @@ package provides command line tools using the Bio++ library.")
                   #t))))
     (build-system gnu-build-system)
     (arguments
-     `(;; There are three(!) tests for this massive library, and all fail with
+     `(;; There are two(!) tests for this massive library, and both fail with
        ;; "unparsable timing stats".
-       ;; ERR [127] --  [util/regexp] test_pcre.sh     (unparsable timing stats)
        ;; ERR [127] --  [serial/datatool] datatool.sh     (unparsable timing stats)
        ;; ERR [127] --  [serial/datatool] datatool_xml.sh     (unparsable timing stats)
        #:tests? #f
@@ -1014,6 +1010,7 @@ package provides command line tools using the Bio++ library.")
             ;; Rewrite hardcoded paths to various tools
             (substitute* (append '("src/build-system/configure.ac"
                                    "src/build-system/configure"
+                                   "src/build-system/helpers/run_with_lock.c"
                                    "scripts/common/impl/if_diff.sh"
                                    "scripts/common/impl/run_with_lock.sh"
                                    "src/build-system/Makefile.configurables.real"
@@ -1062,17 +1059,22 @@ package provides command line tools using the Bio++ library.")
                                              (assoc-ref inputs "bzip2"))
                               (string-append "--with-z="
                                              (assoc-ref inputs "zlib"))
+                              (string-append "--with-pcre="
+                                             (assoc-ref inputs "pcre"))
                               ;; Each library is built twice by default, once
                               ;; with "-static" in its name, and again
                               ;; without.
                               "--without-static"
                               "--with-dll"))))))))
-    (outputs '("out"       ;  19 MB
-               "lib"       ; 203 MB
-               "include")) ;  32 MB
+    (outputs '("out"       ;  21 MB
+               "lib"       ; 226 MB
+               "include")) ;  33 MB
     (inputs
      `(("bzip2" ,bzip2)
-       ("zlib" ,zlib)))
+       ("zlib" ,zlib)
+       ("pcre" ,pcre)
+       ("perl" ,perl)
+       ("python" ,python-wrapper)))
     (native-inputs
      `(("cpio" ,cpio)))
     (home-page "http://blast.ncbi.nlm.nih.gov")
@@ -1188,7 +1190,7 @@ errors at the end of reads.")
 (define-public bowtie
   (package
     (name "bowtie")
-    (version "2.2.9")
+    (version "2.3.2")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://github.com/BenLangmead/bowtie2/archive/v"
@@ -1196,7 +1198,7 @@ errors at the end of reads.")
               (file-name (string-append name "-" version ".tar.gz"))
               (sha256
                (base32
-                "1vp5db8i7is57iwjybcdg18f5ivyzlj5g1ix1nlvxainzivhz55g"))
+                "0hwa5r9qbglppb7sz5z79rlmmddr3n51n468jb3wh8rwjgn3yr90"))
               (modules '((guix build utils)))
               (snippet
                '(substitute* "Makefile"
@@ -1204,28 +1206,28 @@ errors at the end of reads.")
                   (("-DBUILD_HOST=.*") "-DBUILD_HOST=\"\\\"guix\\\"\"")
                   (("-DBUILD_TIME=.*") "-DBUILD_TIME=\"\\\"0\\\"\"")))))
     (build-system gnu-build-system)
-    (inputs `(("perl" ,perl)
-              ("perl-clone" ,perl-clone)
-              ("perl-test-deep" ,perl-test-deep)
-              ("perl-test-simple" ,perl-test-simple)
-              ("python" ,python-2)
-              ("tbb" ,tbb)))
+    (inputs
+     `(("perl" ,perl)
+       ("perl-clone" ,perl-clone)
+       ("perl-test-deep" ,perl-test-deep)
+       ("perl-test-simple" ,perl-test-simple)
+       ("python" ,python-2)
+       ("tbb" ,tbb)
+       ("zlib" ,zlib)))
     (arguments
      '(#:make-flags
        (list "allall"
              "WITH_TBB=1"
              (string-append "prefix=" (assoc-ref %outputs "out")))
        #:phases
-       (alist-delete
-        'configure
-        (alist-replace
-         'check
-         (lambda* (#:key outputs #:allow-other-keys)
-           (system* "perl"
-                    "scripts/test/simple_tests.pl"
-                    "--bowtie2=./bowtie2"
-                    "--bowtie2-build=./bowtie2-build"))
-         %standard-phases))))
+       (modify-phases %standard-phases
+         (delete 'configure)
+         (replace 'check
+           (lambda* (#:key outputs #:allow-other-keys)
+             (zero? (system* "perl"
+                             "scripts/test/simple_tests.pl"
+                             "--bowtie2=./bowtie2"
+                             "--bowtie2-build=./bowtie2-build")))))))
     (home-page "http://bowtie-bio.sourceforge.net/bowtie2/index.shtml")
     (synopsis "Fast and sensitive nucleotide sequence read aligner")
     (description
@@ -1417,7 +1419,7 @@ multiple sequence alignments.")
 (define-public python-pysam
   (package
     (name "python-pysam")
-    (version "0.10.0")
+    (version "0.11.2.2")
     (source (origin
               (method url-fetch)
               ;; Test data is missing on PyPi.
@@ -1427,7 +1429,7 @@ multiple sequence alignments.")
               (file-name (string-append name "-" version ".tar.gz"))
               (sha256
                (base32
-                "1mmvn91agr238kwz7226xq0i7k84lg2nxywn9712mzj7gvgqhfy8"))
+                "1cfqdxsqs3xhacns9n0271ck6wkc76px66ddjm91wfw2jxxfklvc"))
               (modules '((guix build utils)))
               (snippet
                ;; Drop bundled htslib. TODO: Also remove samtools and bcftools.
@@ -1526,13 +1528,13 @@ UCSC genome browser.")
 (define-public python-plastid
   (package
     (name "python-plastid")
-    (version "0.4.6")
+    (version "0.4.8")
     (source (origin
               (method url-fetch)
               (uri (pypi-uri "plastid" version))
               (sha256
                (base32
-                "1sqkz5d3b9kf688mp7k771c87ins42j7j0whmkb49cb3fsg8s8lj"))))
+                "0l24dd3q66if8yj042m4s0g95n6acn7im1imqd3p6h8ns43kxhj8"))))
     (build-system python-build-system)
     (arguments
      ;; Some test files are not included.
@@ -1562,15 +1564,16 @@ high-throughput sequencing data – with an emphasis on simplicity.")
 (define-public cd-hit
   (package
     (name "cd-hit")
-    (version "4.6.6")
+    (version "4.6.8")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://github.com/weizhongli/cdhit"
                                   "/releases/download/V" version
-                                  "/cd-hit-v" version "-2016-0711.tar.gz"))
+                                  "/cd-hit-v" version
+                                  "-2017-0621-source.tar.gz"))
               (sha256
                (base32
-                "1w8hd4fszgg29nqiz569fldwy012la77nljcmlhglgicws56z54p"))))
+                "1386dg2npx8p62wmv08mjzsd2z3waknb9j1gg3gkvblcy57hymnn"))))
     (build-system gnu-build-system)
     (arguments
      `(#:tests? #f ; there are no tests
@@ -1590,7 +1593,7 @@ high-throughput sequencing data – with an emphasis on simplicity.")
                (("__DATE__") "\"0\"")
                (("\", %s, \" __TIME__ \"\\\\n\", date") ""))
              #t))
-         ;; The "install" target does not create the target directory
+         ;; The "install" target does not create the target directory.
          (add-before 'install 'create-target-dir
            (lambda* (#:key outputs #:allow-other-keys)
              (mkdir-p (string-append (assoc-ref outputs "out") "/bin"))
@@ -1634,7 +1637,7 @@ databases.")
     (build-system python-build-system)
     (arguments `(#:python ,python-2)) ; only Python 2 is supported
     (inputs
-     `(("htseq" ,htseq)
+     `(("htseq" ,python2-htseq)
        ("python-pybedtools" ,python2-pybedtools)
        ("python-cython" ,python2-cython)
        ("python-scikit-learn" ,python2-scikit-learn)
@@ -2050,11 +2053,29 @@ trees (phylogenies) and characters.")
       (native-inputs `(("python2-nose" ,python2-nose)
                        ,@(package-native-inputs base))))))
 
+(define-public python-py2bit
+  (package
+    (name "python-py2bit")
+    (version "0.2.1")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "py2bit" version))
+       (sha256
+        (base32
+         "1cdf4qlmgwsh1f4k0wdv2sr8x9qn4366p0k3614vbd0fpqiarxrl"))))
+    (build-system python-build-system)
+    (home-page "https://github.com/dpryan79/py2bit")
+    (synopsis "Access 2bit files using lib2bit")
+    (description
+     "This package provides Python bindings for lib2bit to access 2bit files
+with Python.")
+    (license license:expat)))
 
 (define-public deeptools
   (package
     (name "deeptools")
-    (version "2.1.1")
+    (version "2.5.1")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://github.com/fidelram/deepTools/"
@@ -2062,22 +2083,20 @@ trees (phylogenies) and characters.")
               (file-name (string-append name "-" version ".tar.gz"))
               (sha256
                (base32
-                "1nmfin0zjdby3vay3r4flvz94dr6qjhj41ax4yz3vx13j6wz8izd"))))
+                "1q8i12l2gvk4n2s8lhyzwhh9g4qbc8lrk5l7maz00yvd5g6z5540"))))
     (build-system python-build-system)
-    (arguments
-     `(#:python ,python-2))
     (inputs
-     `(("python-scipy" ,python2-scipy)
-       ("python-numpy" ,python2-numpy)
-       ("python-numpydoc" ,python2-numpydoc)
-       ("python-matplotlib" ,python2-matplotlib)
-       ("python-bx-python" ,python2-bx-python)
-       ("python-pysam" ,python2-pysam)
-       ("python-pybigwig" ,python2-pybigwig)))
+     `(("python-scipy" ,python-scipy)
+       ("python-numpy" ,python-numpy)
+       ("python-numpydoc" ,python-numpydoc)
+       ("python-matplotlib" ,python-matplotlib)
+       ("python-pysam" ,python-pysam)
+       ("python-py2bit" ,python-py2bit)
+       ("python-pybigwig" ,python-pybigwig)))
     (native-inputs
-     `(("python-mock" ,python2-mock)   ;for tests
-       ("python-nose" ,python2-nose)   ;for tests
-       ("python-pytz" ,python2-pytz))) ;for tests
+     `(("python-mock" ,python-mock)   ;for tests
+       ("python-nose" ,python-nose)   ;for tests
+       ("python-pytz" ,python-pytz))) ;for tests
     (home-page "https://github.com/fidelram/deepTools")
     (synopsis "Tools for normalizing and visualizing deep-sequencing data")
     (description
@@ -2094,7 +2113,7 @@ identify enrichments with functional annotations of the genome.")
 (define-public diamond
   (package
     (name "diamond")
-    (version "0.9.8")
+    (version "0.9.9")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2103,7 +2122,7 @@ identify enrichments with functional annotations of the genome.")
               (file-name (string-append name "-" version ".tar.gz"))
               (sha256
                (base32
-                "04f501vj3i95i2b4n60831k00ljalifrq33419bbz0y3sjlmcnj3"))))
+                "04i03046g3l2vk9722z47r1p7j415g97vvz6d76ywmbawyiihcb1"))))
     (build-system cmake-build-system)
     (arguments
      '(#:tests? #f ; no "check" target
@@ -2711,7 +2730,8 @@ comment or quality sections.")
               (file-name (string-append name "-" version ".tar.gz"))
               (sha256
                (base32
-                "055ynn16gd12pf78n4vr2a9jlwsbwzajpdnf2y2yilg1krfff222"))))
+                "055ynn16gd12pf78n4vr2a9jlwsbwzajpdnf2y2yilg1krfff222"))
+              (patches (search-patches "gemma-intel-compat.patch"))))
     (inputs
      `(("gsl" ,gsl)
        ("lapack" ,lapack)
@@ -2719,11 +2739,13 @@ comment or quality sections.")
     (build-system gnu-build-system)
     (arguments
      `(#:make-flags
-       '(,@(if (any (cute string-prefix? <> (or (%current-system)
-                                                (%current-target-system)))
-                    '("x86_64" "mips64el" "aarch64"))
-             '("FORCE_DYNAMIC=1") ; use shared libs
-             '("FORCE_DYNAMIC=1" "FORCE_32BIT=1")))
+       '(,@(match (%current-system)
+         ("x86_64-linux"
+          '("FORCE_DYNAMIC=1"))
+         ("i686-linux"
+          '("FORCE_DYNAMIC=1" "FORCE_32BIT=1"))
+         (_
+          '("FORCE_DYNAMIC=1" "NO_INTEL_COMPAT=1"))))
        #:phases
        (modify-phases %standard-phases
          (delete 'configure)
@@ -2960,22 +2982,22 @@ HMMs).")
 (define-public htseq
   (package
     (name "htseq")
-    (version "0.6.1")
+    (version "0.9.1")
     (source (origin
               (method url-fetch)
-              (uri (string-append
-                    "https://pypi.python.org/packages/source/H/HTSeq/HTSeq-"
-                    version ".tar.gz"))
+              (uri (pypi-uri "HTSeq" version))
               (sha256
                (base32
-                "1i85ppf2j2lj12m0x690qq5nn17xxk23pbbx2c83r8ayb5wngzwv"))))
+                "11flgb1381xdhk43bzbfm3vhnszkpqg6jk76rpa5xd1zbrvvlnxg"))))
     (build-system python-build-system)
-    (arguments `(#:python ,python-2)) ; only Python 2 is supported
+    (native-inputs
+     `(("python-cython" ,python-cython)))
     ;; Numpy needs to be propagated when htseq is used as a Python library.
     (propagated-inputs
-     `(("python-numpy" ,python2-numpy)))
+     `(("python-numpy" ,python-numpy)))
     (inputs
-     `(("python-pysam" ,python2-pysam)))
+     `(("python-pysam" ,python-pysam)
+       ("python-matplotlib" ,python-matplotlib)))
     (home-page "http://www-huber.embl.de/users/anders/HTSeq/")
     (synopsis "Analysing high-throughput sequencing data with Python")
     (description
@@ -2983,6 +3005,9 @@ HMMs).")
 from high-throughput sequencing assays.")
     (license license:gpl3+)))
 
+(define-public python2-htseq
+  (package-with-python2 htseq))
+
 (define-public java-htsjdk
   (package
     (name "java-htsjdk")
@@ -3024,7 +3049,7 @@ manipulating HTS data.")
 (define-public htslib
   (package
     (name "htslib")
-    (version "1.3.1")
+    (version "1.5")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3032,7 +3057,7 @@ manipulating HTS data.")
                     version "/htslib-" version ".tar.bz2"))
               (sha256
                (base32
-                "1rja282fwdc25ql6izkhdyh8ppw8x2fs0w0js78zgkmqjlikmma9"))))
+                "0bcjmnbwp2bib1z1bkrp95w9v2syzdwdfqww10mkb1hxlmg52ax0"))))
     (build-system gnu-build-system)
     (arguments
      `(#:phases
@@ -3044,7 +3069,9 @@ manipulating HTS data.")
               (("/bin/bash") (which "bash")))
             #t)))))
     (inputs
-     `(("zlib" ,zlib)))
+     `(("openssl" ,openssl)
+       ("curl" ,curl)
+       ("zlib" ,zlib)))
     (native-inputs
      `(("perl" ,perl)))
     (home-page "http://www.htslib.org")
@@ -3056,6 +3083,20 @@ data.  It also provides the bgzip, htsfile, and tabix utilities.")
     ;; the rest is released under the Expat license
     (license (list license:expat license:bsd-3))))
 
+;; This package should be removed once no packages rely upon it.
+(define htslib-1.3
+  (package
+    (inherit htslib)
+    (version "1.3.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "https://github.com/samtools/htslib/releases/download/"
+                    version "/htslib-" version ".tar.bz2"))
+              (sha256
+               (base32
+                "1rja282fwdc25ql6izkhdyh8ppw8x2fs0w0js78zgkmqjlikmma9"))))))
+
 (define-public idr
   (package
     (name "idr")
@@ -3430,23 +3471,20 @@ form of assemblies or reads.")
                    license:cpl1.0))))     ; Open Bloom Filter
 
 (define-public metabat
-  ;; We package from a git commit because compilation of the released version
-  ;; fails.
-  (let ((commit "cbdca756993e66ae57e50a27970595dda9cbde1b"))
-    (package
-      (name "metabat")
-      (version (string-append "0.32.4-1." (string-take commit 8)))
-      (source
-       (origin
-         (method git-fetch)
-         (uri (git-reference
-               (url "https://bitbucket.org/berkeleylab/metabat.git")
-               (commit commit)))
-         (file-name (string-append name "-" version))
-         (sha256
-          (base32
-           "0byia8nsip6zvc4ha0qkxkxxyjf4x7jcvy48q2dvb0pzr989syzr"))
-         (patches (search-patches "metabat-remove-compilation-date.patch"))))
+  (package
+    (name "metabat")
+    (version "2.11.2")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (string-append "https://bitbucket.org/berkeleylab/metabat/get/v"
+                           version ".tar.gz"))
+       (file-name (string-append name "-" version ".tar.gz"))
+       (sha256
+        (base32
+         "0rws9r1ziv6way8cf49jg8bzj7x2131kfqkhj8byf0z5hnrq3bwv"))
+       (patches (search-patches "metabat-remove-compilation-date.patch"
+                                "metabat-fix-compilation.patch"))))
     (build-system gnu-build-system)
     (arguments
      `(#:phases
@@ -3463,35 +3501,35 @@ form of assemblies or reads.")
                 "#include \"htslib/kseq.h\""))
              #t))
          (add-after 'unpack 'fix-scons
-            (lambda* (#:key inputs #:allow-other-keys)
-              (substitute* "SConstruct"
-                (("^htslib_dir = 'samtools'")
-                 (string-append "hitslib_dir = '"
-                                (assoc-ref inputs "htslib")
-                                "'"))
-                (("^samtools_dir = 'samtools'")
-                 (string-append "samtools_dir = '"
-                                (assoc-ref inputs "htslib")
-                                "'"))
-                (("^findStaticOrShared\\('bam', hts_lib")
-                 (string-append "findStaticOrShared('bam', '"
-                                (assoc-ref inputs "samtools")
-                                "/lib'"))
-                ;; Do not distribute README.
-                (("^env\\.Install\\(idir_prefix, 'README\\.md'\\)") ""))
-              #t))
+           (lambda* (#:key inputs #:allow-other-keys)
+             (substitute* "SConstruct"
+               (("^htslib_dir += 'samtools'")
+                (string-append "htslib_dir = '"
+                               (assoc-ref inputs "htslib")
+                               "'"))
+               (("^samtools_dir = 'samtools'")
+                (string-append "samtools_dir = '"
+                               (assoc-ref inputs "samtools")
+                               "'"))
+               (("^findStaticOrShared\\('bam', hts_lib")
+                (string-append "findStaticOrShared('bam', '"
+                               (assoc-ref inputs "samtools")
+                               "/lib'"))
+               ;; Do not distribute README.
+               (("^env\\.Install\\(idir_prefix, 'README\\.md'\\)") ""))
+             #t))
          (delete 'configure)
          (replace 'build
-                  (lambda* (#:key inputs outputs #:allow-other-keys)
-                    (mkdir (assoc-ref outputs "out"))
-                    (zero? (system* "scons"
-                                    (string-append
-                                     "PREFIX="
-                                     (assoc-ref outputs "out"))
-                                    (string-append
-                                     "BOOST_ROOT="
-                                     (assoc-ref inputs "boost"))
-                                    "install"))))
+           (lambda* (#:key inputs outputs #:allow-other-keys)
+             (mkdir (assoc-ref outputs "out"))
+             (zero? (system* "scons"
+                             (string-append
+                              "PREFIX="
+                              (assoc-ref outputs "out"))
+                             (string-append
+                              "BOOST_ROOT="
+                              (assoc-ref inputs "boost"))
+                             "install"))))
          ;; Check and install are carried out during build phase.
          (delete 'check)
          (delete 'install))))
@@ -3512,8 +3550,10 @@ sequences to deconvolute complex microbial communities, or metagenome binning,
 enables the study of individual organisms and their interactions.  MetaBAT is
 an automated metagenome binning software, which integrates empirical
 probabilistic distances of genome abundance and tetranucleotide frequency.")
-   (license (license:non-copyleft "file://license.txt"
-                                  "See license.txt in the distribution.")))))
+    ;; The source code contains inline assembly.
+    (supported-systems '("x86_64-linux" "i686-linux"))
+    (license (license:non-copyleft "file://license.txt"
+                                   "See license.txt in the distribution."))))
 
 (define-public minced
   (package
@@ -4293,6 +4333,8 @@ extremely diverse sets of genomes.")
     (description
      "RAxML is a tool for phylogenetic analysis and post-analysis of large
 phylogenies.")
+    ;; The source includes x86 specific code
+    (supported-systems '("x86_64-linux" "i686-linux"))
     (license license:gpl2+)))
 
 (define-public rsem
@@ -4485,7 +4527,7 @@ to the user's query of interest.")
 (define-public samtools
   (package
     (name "samtools")
-    (version "1.3.1")
+    (version "1.5")
     (source
      (origin
        (method url-fetch)
@@ -4494,7 +4536,7 @@ to the user's query of interest.")
                        version "/samtools-" version ".tar.bz2"))
        (sha256
         (base32
-         "0znnnxc467jbf1as2dpskrjhfh8mbll760j6w6rdkwlwbqsp8gbc"))))
+         "1xidmv0jmfy7l0kb32hdnlshcxgzi1hmygvig0cqrq1fhckdlhl5"))))
     (build-system gnu-build-system)
     (arguments
      `(#:modules ((ice-9 ftw)
@@ -4502,36 +4544,35 @@ to the user's query of interest.")
                   (guix build gnu-build-system)
                   (guix build utils))
        #:make-flags (list (string-append "prefix=" (assoc-ref %outputs "out")))
-       #:configure-flags (list "--with-ncurses")
+       #:configure-flags (list "--with-ncurses" "--with-htslib=system")
        #:phases
-       (alist-cons-after
-        'unpack 'patch-tests
-        (lambda _
-          (substitute* "test/test.pl"
-            ;; The test script calls out to /bin/bash
-            (("/bin/bash") (which "bash")))
-          #t)
-        (alist-cons-after
-         'install 'install-library
-         (lambda* (#:key outputs #:allow-other-keys)
-           (let ((lib (string-append (assoc-ref outputs "out") "/lib")))
-             (install-file "libbam.a" lib)
+       (modify-phases %standard-phases
+         (add-after 'unpack 'patch-tests
+           (lambda _
+             (substitute* "test/test.pl"
+               ;; The test script calls out to /bin/bash
+               (("/bin/bash") (which "bash")))
              #t))
-         (alist-cons-after
-          'install 'install-headers
-          (lambda* (#:key outputs #:allow-other-keys)
-            (let ((include (string-append (assoc-ref outputs "out")
-                                          "/include/samtools/")))
-              (for-each (lambda (file)
-                          (install-file file include))
-                        (scandir "." (lambda (name) (string-match "\\.h$" name))))
-              #t))
-          %standard-phases)))))
+         (add-after 'install 'install-library
+           (lambda* (#:key outputs #:allow-other-keys)
+             (let ((lib (string-append (assoc-ref outputs "out") "/lib")))
+               (install-file "libbam.a" lib)
+               #t)))
+         (add-after 'install 'install-headers
+           (lambda* (#:key outputs #:allow-other-keys)
+             (let ((include (string-append (assoc-ref outputs "out")
+                                           "/include/samtools/")))
+               (for-each (lambda (file)
+                           (install-file file include))
+                         (scandir "." (lambda (name) (string-match "\\.h$" name))))
+               #t))))))
     (native-inputs `(("pkg-config" ,pkg-config)))
-    (inputs `(("ncurses" ,ncurses)
-              ("perl" ,perl)
-              ("python" ,python)
-              ("zlib" ,zlib)))
+    (inputs
+     `(("htslib" ,htslib)
+       ("ncurses" ,ncurses)
+       ("perl" ,perl)
+       ("python" ,python)
+       ("zlib" ,zlib)))
     (home-page "http://samtools.sourceforge.net")
     (synopsis "Utilities to efficiently manipulate nucleotide sequence alignments")
     (description
@@ -5289,6 +5330,8 @@ and operational taxonomic unit (OTU) picking of next generation
 sequencing (NGS) reads.  The core algorithm is based on approximate seeds and
 allows for fast and sensitive analyses of nucleotide sequences.  The main
 application of SortMeRNA is filtering rRNA from metatranscriptomic data.")
+    ;; The source includes x86 specific code
+    (supported-systems '("x86_64-linux" "i686-linux"))
     (license license:lgpl3)))
 
 (define-public star
@@ -5713,14 +5756,14 @@ high-throughput sequencing experiments.")
 (define-public r-deseq2
   (package
     (name "r-deseq2")
-    (version "1.16.0")
+    (version "1.16.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DESeq2" version))
        (sha256
         (base32
-         "0m0apn3xi4kdkinsj4xkw5cwysicyjr6xxlxhpa4scyv589am1s5"))))
+         "01pvyljxkwazxl510v7h0971nx65iqd2bdkbdhw3xzind0n9pdvq"))))
     (properties `((upstream-name . "DESeq2")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5750,14 +5793,14 @@ distribution.")
 (define-public r-annotationforge
   (package
     (name "r-annotationforge")
-    (version "1.18.0")
+    (version "1.18.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AnnotationForge" version))
        (sha256
         (base32
-         "01kd86vvgpa4a5zivcy4g6z8rhcykasdskrz8yqsqz211sd1xsr3"))))
+         "1366qvykd9cpcvwgc5g9mm9adw9rxw6p4814dd6l5fyb0pwpmysx"))))
     (properties
      `((upstream-name . "AnnotationForge")))
     (build-system r-build-system)
@@ -5828,14 +5871,14 @@ Enrichment Analysis} (GSEA).")
 (define-public r-category
   (package
     (name "r-category")
-    (version "2.42.0")
+    (version "2.42.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Category" version))
        (sha256
         (base32
-         "0swcmihyjg0fhaaydl9hm24aj9zffw3bibza9y6sqs6jaqd97f09"))))
+         "1w186nhc85bglcgmbcrsdbb8l6rph21pl5kdwjqwkp0jnr9z0ifn"))))
     (properties `((upstream-name . "Category")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6340,13 +6383,13 @@ also known as views, in a controlled vocabulary.")
 (define-public r-bookdown
   (package
   (name "r-bookdown")
-  (version "0.3")
+  (version "0.4")
   (source (origin
             (method url-fetch)
             (uri (cran-uri "bookdown" version))
             (sha256
              (base32
-              "0r9bchzg7im6psc3jphvshzbidc5bv5xaih1qg7b5518jy4iyvb9"))))
+              "1fp1k7hivrb7s2dwgrsqy9s7xg6pk9hczhrc149y1dwh901j6qvv"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-htmltools" ,r-htmltools)
@@ -6362,13 +6405,13 @@ authoring books and technical documents with R Markdown.")
 (define-public r-biocstyle
   (package
    (name "r-biocstyle")
-   (version "2.4.0")
+   (version "2.4.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocStyle" version))
               (sha256
                (base32
-                "1n2c8rj920wmk3q2khmjfnhn5i4b3lmhx1whnghk0zk3jf88hvbi"))))
+                "0bmgmsfll923v573g0kyzlmjd7gly5jwgd8vkrcwvbam1gz75f2c"))))
     (properties
      `((upstream-name . "BiocStyle")))
     (build-system r-build-system)
@@ -6456,14 +6499,14 @@ support for default values, positional argument support, etc.")
 (define-public r-optparse
   (package
     (name "r-optparse")
-    (version "1.3.2")
+    (version "1.4.4")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "optparse" version))
        (sha256
         (base32
-         "1g8as89r91xxi5j5azsd6vrfrhg84mnfx2683j7pacdp8s33radw"))))
+         "1ff4wmsszrb3spwfp7ynfs8w11qpy1sdzfxm1wk8dqqvdwris7qb"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-getopt" ,r-getopt)))
@@ -6479,13 +6522,13 @@ that accept short and long options.")
 (define-public r-dnacopy
   (package
     (name "r-dnacopy")
-    (version "1.50.0")
+    (version "1.50.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DNAcopy" version))
               (sha256
                (base32
-                "0112ry62z18m7rdyrn3gvbxq2f6m44cawhcfb1f02z9xzlsj0k28"))))
+                "0f0x83db7rm5xf9fg5pjhvs4i165qqaf01lbwb8kj13fsqpwx15p"))))
     (properties
      `((upstream-name . "DNAcopy")))
     (build-system r-build-system)
@@ -6501,13 +6544,13 @@ abnormal copy number.")
 (define-public r-s4vectors
   (package
     (name "r-s4vectors")
-    (version "0.14.0")
+    (version "0.14.3")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "S4Vectors" version))
               (sha256
                (base32
-                "0ywwrs4d752xfk0p0w122kvi0xvp6nmxnyynchbsa8zciqymhgv8"))))
+                "1r7s4pfw026qazzic090mhk8d9m39j2nwl87dyqcpdylyq7gq5qs"))))
     (properties
      `((upstream-name . "S4Vectors")))
     (build-system r-build-system)
@@ -6528,14 +6571,14 @@ S4Vectors package itself.")
 (define-public r-seqinr
   (package
     (name "r-seqinr")
-    (version "3.3-6")
+    (version "3.4-5")
     (source
       (origin
         (method url-fetch)
         (uri (cran-uri "seqinr" version))
         (sha256
           (base32
-            "13d0qxm2244wgdl2dy2s8vnrnf5fx4n47if9gkb49dqx6c0sx8s2"))))
+            "17zv0n5cji17izwmwg0jcbxbjl3w5rls91w15svcnlpxjms38ahn"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-ade4" ,r-ade4)
@@ -6553,13 +6596,13 @@ utilities for sequence data management under the ACNUC system.")
 (define-public r-iranges
   (package
     (name "r-iranges")
-    (version "2.10.0")
+    (version "2.10.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "IRanges" version))
               (sha256
                (base32
-                "0zp4mxm9h1p4krj7m7cinkvwa2ibqkq59jwpan97yvhb4z8q0d6n"))))
+                "1brmzs3rsf97gymridrh9c9r3vws8b3rpghaanxnniw36lmcajfy"))))
     (properties
      `((upstream-name . "IRanges")))
     (build-system r-build-system)
@@ -6605,13 +6648,13 @@ ID and species.  It is used by functions in the GenomeInfoDb package.")
 (define-public r-genomeinfodb
   (package
     (name "r-genomeinfodb")
-    (version "1.12.0")
+    (version "1.12.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomeInfoDb" version))
               (sha256
                (base32
-                "1bwwhscjl376a5p43mx8ijrqajxmgypbqhv049pgagl22hkkf0y3"))))
+                "1hjxgmcnrngp1307ipqaq9hgxz4j0ldn7d46knhzs30k2r4qnrfp"))))
     (properties
      `((upstream-name . "GenomeInfoDb")))
     (build-system r-build-system)
@@ -6660,13 +6703,13 @@ CAGE.")
 (define-public r-variantannotation
   (package
     (name "r-variantannotation")
-    (version "1.22.0")
+    (version "1.22.3")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "VariantAnnotation" version))
               (sha256
                (base32
-                "05hpm4as36kvpiqhgnkfjwfx0a05p304c21ggba29iac4nanm8b3"))))
+                "0sr3vdn85x5zdxh80cfwlpfdpi2hmjy3fwi00ac3jya4v145vawr"))))
     (properties
      `((upstream-name . "VariantAnnotation")))
     (inputs
@@ -6698,13 +6741,13 @@ coding changes and predict coding outcomes.")
 (define-public r-limma
   (package
     (name "r-limma")
-    (version "3.32.0")
+    (version "3.32.5")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "limma" version))
               (sha256
                (base32
-                "0q7rqm86nwq0rg4fjggfr7xqybjrxj425vni3cva70b4c8d1h425"))))
+                "0p2ayha9g9w5r8s7pgdf16mkmdbqwh6f35jh07g3b8gyra48gwiw"))))
     (build-system r-build-system)
     (home-page "http://bioinf.wehi.edu.au/limma")
     (synopsis "Package for linear models for microarray and RNA-seq data")
@@ -6753,13 +6796,13 @@ different technologies, including microarrays, RNA-seq, and quantitative PCR.")
 (define-public r-genomicranges
   (package
     (name "r-genomicranges")
-    (version "1.28.0")
+    (version "1.28.4")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicRanges" version))
               (sha256
                (base32
-                "10x9zx0b7j05d1j6p0xs4q4f4wzbhf3rq64wzi9cgv7f44q43a5n"))))
+                "1y15kg1q81h8rmga83ljiwr8whkajcargfjiljr212d6if17ys1z"))))
     (properties
      `((upstream-name . "GenomicRanges")))
     (build-system r-build-system)
@@ -6782,13 +6825,13 @@ manipulating genomic intervals and variables defined along a genome.")
 (define-public r-biobase
   (package
     (name "r-biobase")
-    (version "2.36.0")
+    (version "2.36.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Biobase" version))
               (sha256
                (base32
-                "0x7pf5xsdcj12dbf5qqki2c6bd5madqg2fbiq5xgisarpc9v6c1m"))))
+                "0sr48nqx5bqid4g6lr9zr9286xh842w717yvmssvddb5xxynib6f"))))
     (properties
      `((upstream-name . "Biobase")))
     (build-system r-build-system)
@@ -6804,13 +6847,13 @@ on Bioconductor or which replace R functions.")
 (define-public r-annotationdbi
   (package
     (name "r-annotationdbi")
-    (version "1.38.0")
+    (version "1.38.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AnnotationDbi" version))
               (sha256
                (base32
-                "1xffm98s817mfc827cnr0by6167nlrl1glxzjawzz0rkghs41g27"))))
+                "1lsamnbf07zzsy5asy5hn97n2a4layv58w2bzd90ikcdx0gmzarj"))))
     (properties
      `((upstream-name . "AnnotationDbi")))
     (build-system r-build-system)
@@ -6831,13 +6874,13 @@ annotation data packages using SQLite data storage.")
 (define-public r-biomart
   (package
     (name "r-biomart")
-    (version "2.32.0")
+    (version "2.32.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "biomaRt" version))
               (sha256
                (base32
-                "0knkxh23vl9pa0by03xr6dy9aiah714cmf54jl828k51l9wv5l2j"))))
+                "0fhpbjlsgbqxrpj6nzhhk9q3ph81n5x4p7mmd097xjjn6b05w1d8"))))
     (properties
      `((upstream-name . "biomaRt")))
     (build-system r-build-system)
@@ -6861,13 +6904,13 @@ powerful online queries from gene annotation to database mining.")
 (define-public r-biocparallel
   (package
     (name "r-biocparallel")
-    (version "1.10.0")
+    (version "1.10.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocParallel" version))
               (sha256
                (base32
-                "01ph0kq70b5gkd7n6a4myjlvwzgc0hi4xfwz8h17h06n9p5sdwa9"))))
+                "08mdfxyk9nwz77v0xhlvs19p2wj0phgm5c5b25vm0xh3749njsp0"))))
     (properties
      `((upstream-name . "BiocParallel")))
     (build-system r-build-system)
@@ -6885,13 +6928,13 @@ objects.")
 (define-public r-biostrings
   (package
     (name "r-biostrings")
-    (version "2.44.0")
+    (version "2.44.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Biostrings" version))
               (sha256
                (base32
-                "0ixgx12cx2z4n2khxq83crz9gc21qckj2v78y2p31567kfsw7clg"))))
+                "12c5abgshwq86357jr0r9039y6vl4d6ngysy89rsnr23ldnsirjp"))))
     (properties
      `((upstream-name . "Biostrings")))
     (build-system r-build-system)
@@ -6955,13 +6998,13 @@ files.")
 (define-public r-delayedarray
   (package
     (name "r-delayedarray")
-    (version "0.2.0")
+    (version "0.2.7")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DelayedArray" version))
               (sha256
                (base32
-                "0pcsk0f2dg2ldzprs1cccqrk53jrysmm6ccgjj5wh6z3x17g7g2r"))))
+                "02dfqp4md9xaqjj712ijc3jswghmipr5hwkd5hr0x1xi6l2fb69g"))))
     (properties
      `((upstream-name . "DelayedArray")))
     (build-system r-build-system)
@@ -6985,13 +7028,13 @@ array-like objects like @code{DataFrame} objects (typically with Rle columns),
 (define-public r-summarizedexperiment
   (package
     (name "r-summarizedexperiment")
-    (version "1.6.0")
+    (version "1.6.3")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "SummarizedExperiment" version))
               (sha256
                (base32
-                "1szjbzzz4pyip891nji71caalxh0rhqiv7rpv6q54swlrqpfkqkw"))))
+                "0j7xn7pk52d383fb1wplcggacl2586c4zi0alkgfc3wz7qq9w13s"))))
     (properties
      `((upstream-name . "SummarizedExperiment")))
     (build-system r-build-system)
@@ -7016,13 +7059,13 @@ samples.")
 (define-public r-genomicalignments
   (package
     (name "r-genomicalignments")
-    (version "1.12.0")
+    (version "1.12.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicAlignments" version))
               (sha256
                (base32
-                "1aagyrdk5309a7awg42lg0bpirp91i6i2ddvpmrs38pzriwahnjy"))))
+                "127690sys4i5q3l4vxnjg4xg8q19qlw2258vgs5d1156w9ypp04h"))))
     (properties
      `((upstream-name . "GenomicAlignments")))
     (build-system r-build-system)
@@ -7049,13 +7092,13 @@ alignments.")
 (define-public r-rtracklayer
   (package
     (name "r-rtracklayer")
-    (version "1.36.0")
+    (version "1.36.4")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "rtracklayer" version))
               (sha256
                (base32
-                "0dv7p3wzmx57inznf6fb06417zcm48g7fpazyahxny7bqgzwq0ig"))))
+                "050q1rv04w31168ljr975vxva31n9lqdx84rnmsk6zcr6p640ffp"))))
     (build-system r-build-system)
     (arguments
      `(#:phases
@@ -7094,13 +7137,13 @@ as well as query and modify the browser state, such as the current viewport.")
 (define-public r-genomicfeatures
   (package
     (name "r-genomicfeatures")
-    (version "1.28.0")
+    (version "1.28.4")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicFeatures" version))
               (sha256
                (base32
-                "1pjxlr34ygv8pvfwpyq268wpgqzphiwpij85fyhjqdwdp0a253ik"))))
+                "01ylvg275iy0cvsbxkbfxcf9pi9al597v5wnlqi2xdpmrcxyc3q0"))))
     (properties
      `((upstream-name . "GenomicFeatures")))
     (build-system r-build-system)
@@ -7773,7 +7816,7 @@ throughput genetic sequencing data sets using regression methods.")
 (define-public r-qtl
  (package
   (name "r-qtl")
-  (version "1.40-8")
+  (version "1.41-6")
   (source
    (origin
     (method url-fetch)
@@ -7781,7 +7824,7 @@ throughput genetic sequencing data sets using regression methods.")
                         version ".tar.gz"))
     (sha256
      (base32
-      "05bj1x2ry0i7yqiydlswb3d2h4pxg70z8w1072az1mrv1m54k8sp"))))
+      "067az4v432zxp6lxck8d7vlh9w4r13r0mvw5zsglyaqwsh3d9sad"))))
   (build-system r-build-system)
   (home-page "http://rqtl.org/")
   (synopsis "R package for analyzing QTL experiments in genetics")
@@ -8023,14 +8066,14 @@ in SNV base substitution data.")
 (define-public r-wgcna
   (package
     (name "r-wgcna")
-    (version "1.51")
+    (version "1.60")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "WGCNA" version))
        (sha256
         (base32
-         "0hzvnhw76vwg8bl8x368f0c5szpwb8323bmrb3bir93i5bmfjsxx"))))
+         "16mxhwzhh5q48wmz1iba2r21cp0n0v8g11am4pi52iv6g0663ixl"))))
     (properties `((upstream-name . "WGCNA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8540,14 +8583,14 @@ GenomicRanges Bioconductor package.")
 (define-public r-copywriter
   (package
     (name "r-copywriter")
-    (version "2.8.0")
+    (version "2.8.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "CopywriteR" version))
        (sha256
         (base32
-         "183nmrqmdf9syqljslvwv7mhs9ar5xizzq98imgsc80q0m25ncjf"))))
+         "0xgqnq5v5213b3nzvlmjysjb7w1bc0iblqpmzbjqn7n0ib0qyhbm"))))
     (properties `((upstream-name . "CopywriteR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8580,18 +8623,21 @@ number detection tools.")
 (define-public r-sva
   (package
     (name "r-sva")
-    (version "3.24.0")
+    (version "3.24.4")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "sva" version))
        (sha256
         (base32
-         "04pxl61iyc845wmqca1qv8kbb8zcp0qp72zgvgki3zzmrph9a362"))))
+         "0wcway4ai9im81xnrzb1vij2iidq5pw24qhjfgacmhxvx3dzhbsc"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-genefilter" ,r-genefilter)
-       ("r-mgcv" ,r-mgcv)))
+       ("r-mgcv" ,r-mgcv)
+       ("r-biocparallel" ,r-biocparallel)
+       ("r-matrixstats" ,r-matrixstats)
+       ("r-limma" ,r-limma)))
     (home-page "http://bioconductor.org/packages/sva")
     (synopsis "Surrogate variable analysis")
     (description
@@ -8607,14 +8653,14 @@ unmodeled, or latent sources of noise.")
 (define-public r-seqminer
   (package
     (name "r-seqminer")
-    (version "5.9")
+    (version "6.0")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "seqminer" version))
        (sha256
         (base32
-         "0sfkxrc9gy5a8fadzyzfzh7l5grasm8cj6cd2nnpv85ws6mqr6qd"))))
+         "057j1l6dip35l1aivilapl2zv9db677b3di2pb3sfgq2sxg0ps3l"))))
     (build-system r-build-system)
     (inputs
      `(("zlib" ,zlib)))