gnu: emacs-sly: Update to 20200228.
[jackhill/guix/guix.git] / gnu / packages / bioconductor.scm
index 89cdda2..167cb00 100644 (file)
@@ -1,5 +1,5 @@
 ;;; GNU Guix --- Functional package management for GNU
-;;; Copyright © 2016, 2017, 2018, 2019 Ricardo Wurmus <rekado@elephly.net>
+;;; Copyright © 2016, 2017, 2018, 2019, 2020 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2016, 2017, 2018 Roel Janssen <roel@gnu.org>
 ;;; Copyright © 2017, 2018, 2019 Tobias Geerinckx-Rice <me@tobias.gr>
 ;;; Copyright © 2019 Simon Tournier <zimon.toutoune@gmail.com>
@@ -224,6 +224,30 @@ Finder (TRF mask).  Only the AGAPS and AMB masks are \"active\" by default.")
 1000genomes phase2 reference genome sequence (hs37d5), based on NCBI GRCh37.")
     (license license:artistic2.0)))
 
+(define-public r-bsgenome-hsapiens-ncbi-grch38
+  (package
+    (name "r-bsgenome-hsapiens-ncbi-grch38")
+    (version "1.3.1000")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BSgenome.Hsapiens.NCBI.GRCh38"
+                              version 'annotation))
+       (sha256
+        (base32
+         "0y75qdq578fh6420vbvsbwmdw8jvr3g06qli2h3vj3pxmjykh9c1"))))
+    (properties `((upstream-name . "BSgenome.Hsapiens.NCBI.GRCh38")))
+    (build-system r-build-system)
+    (propagated-inputs `(("r-bsgenome" ,r-bsgenome)))
+    (home-page
+     "https://bioconductor.org/packages/release/data/annotation/html/\
+BSgenome.Hsapiens.NCBI.GRCh38.html")
+    (synopsis "Full genome sequences for Homo sapiens (GRCh38)")
+    (description
+     "This package provides full genome sequences for Homo sapiens (Human) as
+provided by NCBI (GRCh38, 2013-12-17) and stored in Biostrings objects.")
+    (license license:artistic2.0)))
+
 (define-public r-bsgenome-hsapiens-ucsc-hg19-masked
   (package
     (name "r-bsgenome-hsapiens-ucsc-hg19-masked")
@@ -297,7 +321,7 @@ provided by UCSC (mm9, July 2007) and stored in Biostrings objects.")
      `(("r-bsgenome" ,r-bsgenome)
        ("r-bsgenome-mmusculus-ucsc-mm9"
         ,r-bsgenome-mmusculus-ucsc-mm9)))
-    (home-page "http://bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9.masked/")
+    (home-page "https://bioconductor.org/packages/BSgenome.Mmusculus.UCSC.mm9.masked/")
     (synopsis "Full masked genome sequences for Mouse")
     (description
      "This package provides full genome sequences for Mus musculus (Mouse) as
@@ -594,14 +618,14 @@ database is exposed as a @code{TxDb} object.")
 (define-public r-txdb-mmusculus-ucsc-mm10-knowngene
   (package
     (name "r-txdb-mmusculus-ucsc-mm10-knowngene")
-    (version "3.4.7")
+    (version "3.10.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "TxDb.Mmusculus.UCSC.mm10.knownGene"
                                      version 'annotation))
               (sha256
                (base32
-                "04impkl8zh1gpwwrpbf19jqznsjrq2306yyhm6cmx6hr1401bd6b"))))
+                "0xs9npnhbwll7p62hibs02y4ac23jchdcr25i6a7qwq1kms82qk9"))))
     (properties
      `((upstream-name . "TxDb.Mmusculus.UCSC.mm10.knownGene")))
     (build-system r-build-system)
@@ -694,6 +718,77 @@ annotations.")
      "This is a manifest package for Illumina's EPIC methylation arrays.")
     (license license:artistic2.0)))
 
+;; This is a CRAN package, but it depends on r-bsgenome-hsapiens-ucsc-hg19
+;; from Bioconductor.
+(define-public r-deconstructsigs
+  (package
+    (name "r-deconstructsigs")
+    (version "1.8.0")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "deconstructSigs" version))
+              (sha256
+               (base32
+                "014x0nb23jb98666kaav2phkvmkr38pi38jv0dqd4jv7zp0gdf1a"))))
+    (properties
+     `((upstream-name . "deconstructSigs")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-bsgenome" ,r-bsgenome)
+       ("r-bsgenome-hsapiens-ucsc-hg19" ,r-bsgenome-hsapiens-ucsc-hg19)
+       ("r-genomeinfodb" ,r-genomeinfodb)
+       ("r-reshape2" ,r-reshape2)))
+    (home-page "https://github.com/raerose01/deconstructSigs")
+    (synopsis "Identifies signatures present in a tumor sample")
+    (description "This package takes sample information in the form of the
+fraction of mutations in each of 96 trinucleotide contexts and identifies
+the weighted combination of published signatures that, when summed, most
+closely reconstructs the mutational profile.")
+    (license license:gpl2+)))
+
+;; This is a CRAN package, but it depends on Bioconductor packages.
+(define-public r-nmf
+  (package
+    (name "r-nmf")
+    (version "0.22.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (cran-uri "NMF" version))
+       (sha256
+        (base32
+         "0b2ls3x1nkrnam45hagpys624nzxj3v7kxnp0q216yakvx5h57cq"))))
+    (properties `((upstream-name . "NMF")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-cluster" ,r-cluster)
+       ("r-biobase" ,r-biobase)
+       ("r-biocmanager" ,r-biocmanager)
+       ("r-bigmemory" ,r-bigmemory) ; suggested
+       ("r-synchronicity" ,r-synchronicity) ; suggested
+       ("r-colorspace" ,r-colorspace)
+       ("r-digest" ,r-digest)
+       ("r-doparallel" ,r-doparallel)
+       ("r-foreach" ,r-foreach)
+       ("r-ggplot2" ,r-ggplot2)
+       ("r-gridbase" ,r-gridbase)
+       ("r-pkgmaker" ,r-pkgmaker)
+       ("r-rcolorbrewer" ,r-rcolorbrewer)
+       ("r-registry" ,r-registry)
+       ("r-reshape2" ,r-reshape2)
+       ("r-rngtools" ,r-rngtools)
+       ("r-stringr" ,r-stringr)))
+    (home-page "http://renozao.github.io/NMF")
+    (synopsis "Algorithms and framework for nonnegative matrix factorization")
+    (description
+     "This package provides a framework to perform Non-negative Matrix
+Factorization (NMF).  The package implements a set of already published
+algorithms and seeding methods, and provides a framework to test, develop and
+plug new or custom algorithms.  Most of the built-in algorithms have been
+optimized in C++, and the main interface function provides an easy way of
+performing parallel computations on multicore machines.")
+    (license license:gpl2+)))
+
 (define-public r-do-db
   (package
     (name "r-do-db")
@@ -1053,14 +1148,14 @@ problems in CEL-level data to help evaluate performance of quality metrics.")
 (define-public r-affycoretools
   (package
     (name "r-affycoretools")
-    (version "1.58.2")
+    (version "1.58.4")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affycoretools" version))
        (sha256
         (base32
-         "0cgy9phwdk4x9lr11xh6zs7v8r5xq959fmsmzwrpnd50dr7hzkvd"))))
+         "1p283ysib04qzaayxmrpsmk5bq0jdq2rlky180jrlskpyg6risfw"))))
     (properties `((upstream-name . "affycoretools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1071,6 +1166,7 @@ problems in CEL-level data to help evaluate performance of quality metrics.")
        ("r-dbi" ,r-dbi)
        ("r-edger" ,r-edger)
        ("r-gcrma" ,r-gcrma)
+       ("r-glimma" ,r-glimma)
        ("r-ggplot2" ,r-ggplot2)
        ("r-gostats" ,r-gostats)
        ("r-gplots" ,r-gplots)
@@ -1165,14 +1261,14 @@ the Human Protein Atlas project.")
 (define-public r-regioner
   (package
     (name "r-regioner")
-    (version "1.18.0")
+    (version "1.18.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "regioneR" version))
        (sha256
         (base32
-         "0m073hrqp62zpd2blnqm5ka539hcilir05m8av14vdhzhjzp13ya"))))
+         "0if7r6njz3ahm545383z5mzmzw8fdvw80a9lfz160j5pcgpx2dq9"))))
     (properties `((upstream-name . "regioneR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1399,7 +1495,7 @@ problems in genomics, brain imaging, astrophysics, and data mining.")
        ("r-s4vectors" ,r-s4vectors)
        ("r-summarizedexperiment" ,r-summarizedexperiment)
        ("r-systempiper" ,r-systempiper)))
-    (home-page "http://bioconductor.org/packages/DiffBind")
+    (home-page "https://bioconductor.org/packages/DiffBind")
     (synopsis "Differential binding analysis of ChIP-Seq peak data")
     (description
      "This package computes differentially bound sites from multiple
@@ -1428,7 +1524,7 @@ occupancy (overlap) analysis and plotting functions.")
        ("r-rsamtools" ,r-rsamtools)
        ("r-genomicalignments" ,r-genomicalignments)
        ("r-rtracklayer" ,r-rtracklayer)))
-    (home-page "http://bioconductor.org/packages/RIPSeeker")
+    (home-page "https://bioconductor.org/packages/RIPSeeker")
     (synopsis
      "Identifying protein-associated transcripts from RIP-seq experiments")
     (description
@@ -1457,7 +1553,7 @@ processing to visualization and annotation.")
        ("r-biocgenerics" ,r-biocgenerics)
        ("r-biobase" ,r-biobase)
        ("r-mass" ,r-mass)))
-    (home-page "http://bioconductor.org/packages/multtest")
+    (home-page "https://bioconductor.org/packages/multtest")
     (synopsis "Resampling-based multiple hypothesis testing")
     (description
      "This package can do non-parametric bootstrap and permutation
@@ -1497,6 +1593,30 @@ expressed genes in DNA microarray experiments.")
      "This package implements some simple graph handling capabilities for R.")
     (license license:artistic2.0)))
 
+;; This is a CRAN package, but it depends on a Bioconductor package.
+(define-public r-ggm
+  (package
+    (name "r-ggm")
+    (version "2.5")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (cran-uri "ggm" version))
+       (sha256
+        (base32
+         "11wc6k2kj2ydy0dyks5mbvbhxm1r43id87anl1jg6dn0yv4m78di"))))
+    (properties `((upstream-name . "ggm")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-graph" ,r-graph)
+       ("r-igraph" ,r-igraph)))
+    (home-page "https://cran.r-project.org/package=ggm")
+    (synopsis "Functions for graphical Markov models")
+    (description
+     "This package provides functions and datasets for maximum likelihood
+fitting of some classes of graphical Markov models.")
+    (license license:gpl2+)))
+
 (define-public r-codedepends
   (package
     (name "r-codedepends")
@@ -1514,7 +1634,7 @@ expressed genes in DNA microarray experiments.")
      `(("r-codetools" ,r-codetools)
        ("r-graph" ,r-graph)
        ("r-xml" ,r-xml)))
-    (home-page "http://cran.r-project.org/web/packages/CodeDepends")
+    (home-page "https://cran.r-project.org/web/packages/CodeDepends")
     (synopsis "Analysis of R code for reproducible research and code comprehension")
     (description
      "This package provides tools for analyzing R expressions or blocks of
@@ -1528,14 +1648,14 @@ determining dependencies between variables, code improvement suggestions.")
 (define-public r-chippeakanno
   (package
     (name "r-chippeakanno")
-    (version "3.20.0")
+    (version "3.20.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ChIPpeakAnno" version))
        (sha256
         (base32
-         "0hp3s3shnrb55cxvx9wrdl67wqw9f55gdgx7262s4mahpxjswfsa"))))
+         "0kmfha4vprbi0z6n7v9w28xfrqcx5qad7yfr0b316j5aj8v9f4hc"))))
     (properties `((upstream-name . "ChIPpeakAnno")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1568,7 +1688,7 @@ determining dependencies between variables, code improvement suggestions.")
        ("r-seqinr" ,r-seqinr)
        ("r-summarizedexperiment" ,r-summarizedexperiment)
        ("r-venndiagram" ,r-venndiagram)))
-    (home-page "http://bioconductor.org/packages/ChIPpeakAnno")
+    (home-page "https://bioconductor.org/packages/ChIPpeakAnno")
     (synopsis "Peaks annotation from ChIP-seq and ChIP-chip experiments")
     (description
      "The package includes functions to retrieve the sequences around the peak,
@@ -1593,7 +1713,7 @@ enrichedGO (addGeneIDs).")
     (build-system r-build-system)
     (propagated-inputs
      `(("r-limma" ,r-limma)))
-    (home-page "http://bioconductor.org/packages/marray")
+    (home-page "https://bioconductor.org/packages/marray")
     (synopsis "Exploratory analysis for two-color spotted microarray data")
     (description "This package contains class definitions for two-color spotted
 microarray data.  It also includes functions for data input, diagnostic plots,
@@ -1614,7 +1734,7 @@ normalization and quality checking.")
    (propagated-inputs
     `(("r-biobase" ,r-biobase)
       ("r-marray" ,r-marray)))
-   (home-page "http://bioconductor.org/packages/CGHbase")
+   (home-page "https://bioconductor.org/packages/CGHbase")
    (synopsis "Base functions and classes for arrayCGH data analysis")
    (description "This package contains functions and classes that are needed by
 the @code{arrayCGH} packages.")
@@ -1637,7 +1757,7 @@ the @code{arrayCGH} packages.")
       ("r-impute" ,r-impute)
       ("r-dnacopy" ,r-dnacopy)
       ("r-snowfall" ,r-snowfall)))
-   (home-page "http://bioconductor.org/packages/CGHcall")
+   (home-page "https://bioconductor.org/packages/CGHcall")
    (synopsis "Base functions and classes for arrayCGH data analysis")
    (description "This package contains functions and classes that are needed by
 @code{arrayCGH} packages.")
@@ -1666,7 +1786,7 @@ the @code{arrayCGH} packages.")
        ("r-matrixstats" ,r-matrixstats)
        ("r-r-utils" ,r-r-utils)
        ("r-rsamtools" ,r-rsamtools)))
-    (home-page "http://bioconductor.org/packages/QDNAseq")
+    (home-page "https://bioconductor.org/packages/QDNAseq")
     (synopsis "Quantitative DNA sequencing for chromosomal aberrations")
     (description "The genome is divided into non-overlapping fixed-sized bins,
 number of sequence reads in each counted, adjusted with a simultaneous
@@ -1838,14 +1958,14 @@ experiments.")
 (define-public r-genomicinteractions
   (package
     (name "r-genomicinteractions")
-    (version "1.20.0")
+    (version "1.20.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GenomicInteractions" version))
        (sha256
         (base32
-         "10kwb70c9aq0bfqpq48h186lsbwgrg18m14r9z8x6n8l7cds5azc"))))
+         "140bp7c8p079xh5wwxmrq3a73pm6mdc9czq5w2gzjml7dgrca38a"))))
     (properties
      `((upstream-name . "GenomicInteractions")))
     (build-system r-build-system)
@@ -1999,14 +2119,14 @@ genes or proteins in these datasets.")
 (define-public r-inspect
   (package
     (name "r-inspect")
-    (version "1.16.0")
+    (version "1.16.3")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "INSPEcT" version))
        (sha256
         (base32
-         "043066zygf2y2jp6dvfwl56hkzcdvkmymhjx3gh4mhi48l71zqv9"))))
+         "0y4gpvrbmcipdnyz9lz9ywn0317xnpcriiisqvxygin05vgcpilp"))))
     (properties `((upstream-name . "INSPEcT")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2015,6 +2135,7 @@ genes or proteins in these datasets.")
        ("r-biocparallel" ,r-biocparallel)
        ("r-deseq2" ,r-deseq2)
        ("r-desolve" ,r-desolve)
+       ("r-gdata" ,r-gdata)
        ("r-genomeinfodb" ,r-genomeinfodb)
        ("r-genomicalignments" ,r-genomicalignments)
        ("r-genomicfeatures" ,r-genomicfeatures)
@@ -2095,14 +2216,14 @@ samples.")
 (define-public r-biocneighbors
   (package
     (name "r-biocneighbors")
-    (version "1.4.1")
+    (version "1.4.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocNeighbors" version))
        (sha256
         (base32
-         "05vi1cij37s8wgj92k3l6a3f3dwldj8jvijdp4695zczka6kypdf"))))
+         "1bx7i5pifj8w89fnhfgcfgcar2ik2ad8wqs2rix7yks90vz185i6"))))
     (properties `((upstream-name . "BiocNeighbors")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2126,14 +2247,14 @@ achieved for all methods using the BiocParallel framework.")
 (define-public r-biocsingular
   (package
     (name "r-biocsingular")
-    (version "1.2.0")
+    (version "1.2.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocSingular" version))
        (sha256
         (base32
-         "0qd7r2k56ym7ivjgapxbk7fyj2d7396f1ad1hkgnicgyw1an5q1r"))))
+         "1282fdwxrpga87y8xflr0sl8ajwawgn2i9i65my8mbg5vrixs407"))))
     (properties `((upstream-name . "BiocSingular")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2158,14 +2279,14 @@ possible, parallelization is achieved using the BiocParallel framework.")
 (define-public r-destiny
   (package
     (name "r-destiny")
-    (version "3.0.0")
+    (version "3.0.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "destiny" version))
        (sha256
         (base32
-         "0vj9nk8g6i4vzm6cnzvbsqcvyk6fhmx0a0nxxrciarffyhqk81yz"))))
+         "1hzg53p1cz21bvnfyyz40bpvjhg89zi3rahlqf0c4w85iwc1i4vi"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biobase" ,r-biobase)
@@ -2425,7 +2546,7 @@ gene and isoform level using RNA-seq data")
        ("zlib" ,zlib)))
     (native-inputs
      `(("pkg-config" ,pkg-config)))
-    (home-page "http://r-forge.r-project.org/projects/rsymphony")
+    (home-page "https://r-forge.r-project.org/projects/rsymphony")
     (synopsis "Symphony integer linear programming solver in R")
     (description
      "This package was derived from Rsymphony.  The package provides an R
@@ -3100,27 +3221,20 @@ surface of a flowcell.")
 (define-public r-gkmsvm
   (package
     (name "r-gkmsvm")
-    (version "0.79.0")
+    (version "0.80.0")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "gkmSVM" version))
        (sha256
         (base32
-         "04dakbgfvfalz4rm4fvvybp506dn5fbj5g86ybfhrc6wywjllsz3"))))
+         "0ljcga246ad0ql8x3drvrdsyp0f20mgp3p6lnl79xb76qgfdnm0p"))))
     (properties `((upstream-name . "gkmSVM")))
     (build-system r-build-system)
     (propagated-inputs
-     `(("r-biocgenerics" ,r-biocgenerics)
-       ("r-biostrings" ,r-biostrings)
-       ("r-genomeinfodb" ,r-genomeinfodb)
-       ("r-genomicranges" ,r-genomicranges)
-       ("r-iranges" ,r-iranges)
-       ("r-kernlab" ,r-kernlab)
+     `(("r-kernlab" ,r-kernlab)
        ("r-rcpp" ,r-rcpp)
        ("r-rocr" ,r-rocr)
-       ("r-rtracklayer" ,r-rtracklayer)
-       ("r-s4vectors" ,r-s4vectors)
        ("r-seqinr" ,r-seqinr)))
     (home-page "https://cran.r-project.org/web/packages/gkmSVM")
     (synopsis "Gapped-kmer support vector machine")
@@ -3163,14 +3277,14 @@ are standardized and usable by the accompanying mutossGUI package.")
 (define-public r-metap
   (package
     (name "r-metap")
-    (version "1.2")
+    (version "1.3")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "metap" version))
        (sha256
         (base32
-         "0pfbcixjrzx81l9wqhlp55khg9k63zf8pvg2n39c19akr4ppzhvf"))))
+         "1jmmmmjiklaxfl604hwqil193ydaghvd5jv8xsr4bx3pzn5i9kvz"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-lattice" ,r-lattice)
@@ -3254,14 +3368,14 @@ gmapR.")
 (define-public r-heatplus
   (package
     (name "r-heatplus")
-    (version "2.32.0")
+    (version "2.32.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Heatplus" version))
        (sha256
         (base32
-         "0hx5gqgh4xrkx37ccprq7azj9jziff137bdk0gvrixcx52ws6h89"))))
+         "1ldxj2hasg6ysh70sc73mz2v4h3n8gf3lii09c3sqc4wmz5h7rp1"))))
     (properties `((upstream-name . "Heatplus")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3423,14 +3537,14 @@ data.")
 (define-public r-enrichplot
   (package
     (name "r-enrichplot")
-    (version "1.6.0")
+    (version "1.6.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "enrichplot" version))
        (sha256
         (base32
-         "1jblx00b869xhx1c4n9m2g1hqr00rm9ywr1hrlx42bdd8k5ax1xh"))))
+         "0707f5ll58psh7pr001cmmk5di7dprnbry1cy2mw20vn8p24nf3x"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-annotationdbi" ,r-annotationdbi)
@@ -3458,14 +3572,14 @@ All the visualization methods are developed based on ggplot2 graphics.")
 (define-public r-clusterprofiler
   (package
     (name "r-clusterprofiler")
-    (version "3.14.0")
+    (version "3.14.3")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "clusterProfiler" version))
        (sha256
         (base32
-         "0mm9iafrsjb8sj27k9mg40ab13vq4rmrzhaajm6g1wdkb2jqikjk"))))
+         "08pd7bmqmyxncj09ilz8yb9sf1pv9ni98y8b93pz2giy7pl407hg"))))
     (properties
      `((upstream-name . "clusterProfiler")))
     (build-system r-build-system)
@@ -3491,14 +3605,14 @@ profiles (GO and KEGG) of gene and gene clusters.")
 (define-public r-mlinterfaces
   (package
     (name "r-mlinterfaces")
-    (version "1.66.0")
+    (version "1.66.4")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MLInterfaces" version))
        (sha256
         (base32
-         "1vnzqd3y3jk1wgxybckzrcgwk0ly7zgcz5ki1ib0bk1jwv6xk5x8"))))
+         "19hlicdndy2p45y7w91gnwi3wgq5s465a646z3qqk8gmn5sn614q"))))
     (properties `((upstream-name . "MLInterfaces")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3516,7 +3630,6 @@ profiles (GO and KEGG) of gene and gene clusters.")
        ("r-mlbench" ,r-mlbench)
        ("r-pls" ,r-pls)
        ("r-rcolorbrewer" ,r-rcolorbrewer)
-       ("r-rda" ,r-rda)
        ("r-rpart" ,r-rpart)
        ("r-sfsmisc" ,r-sfsmisc)
        ("r-shiny" ,r-shiny)
@@ -3792,19 +3905,20 @@ fitting a three-component normal mixture on z-scores.")
 (define-public r-rgadem
   (package
     (name "r-rgadem")
-    (version "2.34.0")
+    (version "2.34.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "rGADEM" version))
        (sha256
         (base32
-         "14ylbrzb9haqwfdd9g813mzhll6gwvqf2r7cmbaxz5lkl0j0nglx"))))
+         "12xm4p4qsczf57kip8bvi6pr8sb5gvn11dnbz7lbh6sc03sx3q2h"))))
     (properties `((upstream-name . "rGADEM")))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biostrings" ,r-biostrings)
        ("r-bsgenome" ,r-bsgenome)
+       ("r-genomicranges" ,r-genomicranges)
        ("r-iranges" ,r-iranges)
        ("r-seqlogo" ,r-seqlogo)))
     (home-page "https://bioconductor.org/packages/rGADEM/")
@@ -3912,14 +4026,14 @@ position-specific scores within R and Bioconductor.")
 (define-public r-atacseqqc
   (package
     (name "r-atacseqqc")
-    (version "1.10.1")
+    (version "1.10.3")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ATACseqQC" version))
        (sha256
         (base32
-         "12ix0bvwk50d48z85f3453k7szm1j27gk4qgw56az4fxra472rlh"))))
+         "18zf90iksglbs13cwr4jjwsv332a19lf4bpdmy69jz8bpwrklv22"))))
     (properties `((upstream-name . "ATACseqQC")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3941,6 +4055,8 @@ position-specific scores within R and Bioconductor.")
        ("r-rsamtools" ,r-rsamtools)
        ("r-rtracklayer" ,r-rtracklayer)
        ("r-s4vectors" ,r-s4vectors)))
+    (native-inputs
+     `(("r-knitr" ,r-knitr)))
     (home-page "https://bioconductor.org/packages/ATACseqQC/")
     (synopsis "ATAC-seq quality control")
     (description
@@ -4201,14 +4317,14 @@ visualization with image data.")
 (define-public r-yamss
   (package
     (name "r-yamss")
-    (version "1.12.0")
+    (version "1.12.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "yamss" version))
        (sha256
         (base32
-         "1n49a2vg1667wycrjww29xfafngllvpb5nq5wy6pgn0akva91nky"))))
+         "12jr7hbrwhb1gfjadj1024hv80ra22miy46dn40nmsrbklkfn3rw"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biocgenerics" ,r-biocgenerics)
@@ -4579,14 +4695,14 @@ based on @dfn{Continuous Wavelet Transform} (CWT).")
 (define-public r-xcms
   (package
     (name "r-xcms")
-    (version "3.8.1")
+    (version "3.8.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "xcms" version))
        (sha256
         (base32
-         "18iglvlvlxrdwn2apdvihj9jxmx0kwm5z37rml67xcj9sfdi3bjb"))))
+         "0bfl56v3l6k31i11l09nx1yqfjy6z5yragm6k83z4w0mpgk18y7g"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biobase" ,r-biobase)
@@ -5162,14 +5278,14 @@ packages.")
 (define-public r-ropls
   (package
     (name "r-ropls")
-    (version "1.18.0")
+    (version "1.18.8")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ropls" version))
        (sha256
         (base32
-         "05w1zrq92w3jfwq5sdyj27m5qjg4zv7acywia8vd6y5fbgcnyzlp"))))
+         "033i39r4037nd54jnp5zdn1vpzh61r671vmq0sf8dqrfblhm4w7a"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biobase" ,r-biobase)
@@ -5275,14 +5391,14 @@ annotations.")
 (define-public r-rsubread
   (package
     (name "r-rsubread")
-    (version "2.0.0")
+    (version "2.0.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rsubread" version))
        (sha256
         (base32
-         "0l8q9y2a4m1di0w5nlxhq9jgliinhgr2fwjpm5ixnqx5j3iprlwd"))))
+         "0pdkx9mhvzw3a4ff725qvda9bxvs9vh2ppb29cc5jrivgjndv5cy"))))
     (properties `((upstream-name . "Rsubread")))
     (build-system r-build-system)
     (inputs `(("zlib" ,zlib)))
@@ -5584,14 +5700,14 @@ for other R packages to compile and link against.")
 (define-public r-flowworkspace
   (package
     (name "r-flowworkspace")
-    (version "3.34.0")
+    (version "3.34.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowWorkspace" version))
        (sha256
         (base32
-         "0hvbkxyylsygra31l1lxyvbsr5hc50lqy1y7gwrfgrfil4a2m762"))))
+         "1ijbc6z9ljhrw3cqr02smgplhrfg44gzrb1dq4gbrpq3nj4khhpn"))))
     (properties `((upstream-name . "flowWorkspace")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5787,14 +5903,14 @@ self-organizing map clustering and minimal spanning trees.")
 (define-public r-mixomics
   (package
     (name "r-mixomics")
-    (version "6.10.6")
+    (version "6.10.8")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "mixOmics" version))
        (sha256
         (base32
-         "18jwrdyc4pnx917y1kskxz3fqvlrkyy4ny0xqrfcidz0j7p0b7wr"))))
+         "0307vhx9ck24rxqbvq15815ssxcc226sl2la060n204b51wi9jaa"))))
     (properties `((upstream-name . "mixOmics")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5829,14 +5945,14 @@ delete entire rows with missing data.")
 (define-public r-depecher
   (package
     (name "r-depecher")
-    (version "1.2.0")
+    (version "1.2.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DepecheR" version))
        (sha256
         (base32
-         "1f6zbc0fq7xjflh3mkjx1n83mpppw663dj22rlpxzwp1kpmf6wm5"))))
+         "199j2kw0xnw7y4v1gakm2jgyc7zzlj8xh0570f2yjq55gp1kggbm"))))
     (properties `((upstream-name . "DepecheR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5856,6 +5972,8 @@ delete entire rows with missing data.")
        ("r-reshape2" ,r-reshape2)
        ("r-robustbase" ,r-robustbase)
        ("r-viridis" ,r-viridis)))
+    (native-inputs
+     `(("r-knitr" ,r-knitr)))
     (home-page "https://bioconductor.org/packages/DepecheR/")
     (synopsis "Identify traits of clusters in high-dimensional entities")
     (description
@@ -5907,14 +6025,14 @@ genes in the gene-set that are ranked above the leading edge).")
 (define-public r-cicero
   (package
     (name "r-cicero")
-    (version "1.4.0")
+    (version "1.4.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "cicero" version))
        (sha256
         (base32
-         "0mmm7vvzq50b5fayid0bw82b5lar3xm9fwl2ya30q0p4db2y6wnz"))))
+         "154djqd32w87814ycfmfz27ikp17bnampvmvw5hzi5p2x9l3h82r"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-assertthat" ,r-assertthat)
@@ -5936,6 +6054,7 @@ genes in the gene-set that are ranked above the leading edge).")
        ("r-s4vectors" ,r-s4vectors)
        ("r-stringr" ,r-stringr)
        ("r-tibble" ,r-tibble)
+       ("r-tidyr" ,r-tidyr)
        ("r-vgam" ,r-vgam)))
     (home-page "https://bioconductor.org/packages/cicero/")
     (synopsis "Predict cis-co-accessibility from single-cell data")
@@ -6449,14 +6568,14 @@ arrays based on fast wavelet-based functional models.")
 (define-public r-variancepartition
   (package
     (name "r-variancepartition")
-    (version "1.16.0")
+    (version "1.16.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "variancePartition" version))
        (sha256
         (base32
-         "1ygx7f2sp4b7ilgspm6vqcbjxs7br9s6g3gwcdb978kx03ymp4i8"))))
+         "02pzsff14j4am2d949mh8xgi0c7k44g09q4lr6nqm08vf92brb6g"))))
     (properties
      `((upstream-name . "variancePartition")))
     (build-system r-build-system)
@@ -7038,3 +7157,370 @@ visualize bioinformatics analyses.")
 and automates the conversion of node identifiers (e.g. from Entrez IDs to gene
 symbols).")
     (license license:agpl3+)))
+
+(define-public r-reactomepa
+  (package
+    (name "r-reactomepa")
+    (version "1.30.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "ReactomePA" version))
+       (sha256
+        (base32
+         "1vwc9kj1l4yi7c4f4lnq0i3wl2nrmmhcxyakz8qak122fi92z3j1"))))
+    (properties `((upstream-name . "ReactomePA")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-annotationdbi" ,r-annotationdbi)
+       ("r-dose" ,r-dose)
+       ("r-enrichplot" ,r-enrichplot)
+       ("r-ggplot2" ,r-ggplot2)
+       ("r-ggraph" ,r-ggraph)
+       ("r-graphite" ,r-graphite)
+       ("r-igraph" ,r-igraph)
+       ("r-reactome-db" ,r-reactome-db)))
+    (home-page "https://guangchuangyu.github.io/software/ReactomePA")
+    (synopsis "Reactome pathway analysis")
+    (description
+     "This package provides functions for pathway analysis based on the
+REACTOME pathway database.  It implements enrichment analysis, gene set
+enrichment analysis and several functions for visualization.")
+    (license license:gpl2)))
+
+(define-public r-ebarrays
+  (package
+    (name "r-ebarrays")
+    (version "2.50.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "EBarrays" version))
+       (sha256
+        (base32
+         "063rhsdp8x0f881kslq06zxfp6b2qabrz4vmfrn8a4v3pd3n7s13"))))
+    (properties `((upstream-name . "EBarrays")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biobase" ,r-biobase)
+       ("r-cluster" ,r-cluster)
+       ("r-lattice" ,r-lattice)))
+    (home-page "https://bioconductor.org/packages/EBarrays/")
+    (synopsis "Gene clustering and differential expression identification")
+    (description
+     "EBarrays provides tools for the analysis of replicated/unreplicated
+microarray data.")
+    (license license:gpl2+)))
+
+(define-public r-bioccasestudies
+  (package
+    (name "r-bioccasestudies")
+    (version "1.48.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BiocCaseStudies" version))
+       (sha256
+        (base32
+         "1sg9vxs24zfz3dg9y0qlrdsq43y0pbahbvcfxzlxjzjw80xzxpbd"))))
+    (properties
+     `((upstream-name . "BiocCaseStudies")))
+    (build-system r-build-system)
+    (propagated-inputs `(("r-biobase" ,r-biobase)))
+    (home-page "https://bioconductor.org/packages/BiocCaseStudies")
+    (synopsis "Support for the case studies monograph")
+    (description
+     "This package provides software and data to support the case studies
+monograph.")
+    (license license:artistic2.0)))
+
+(define-public r-biocgraph
+  (package
+    (name "r-biocgraph")
+    (version "1.48.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "biocGraph" version))
+       (sha256
+        (base32
+         "1rv2lwiqwg7h7za23n896fs4dpla3xhw6kzwghb6iw5nlm2m61yw"))))
+    (properties `((upstream-name . "biocGraph")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biocgenerics" ,r-biocgenerics)
+       ("r-geneplotter" ,r-geneplotter)
+       ("r-graph" ,r-graph)
+       ("r-rgraphviz" ,r-rgraphviz)))
+    (home-page "https://bioconductor.org/packages/biocGraph/")
+    (synopsis "Graph examples and use cases in Bioinformatics")
+    (description
+     "This package provides examples and code that make use of the
+different graph related packages produced by Bioconductor.")
+    (license license:artistic2.0)))
+
+(define-public r-experimenthub
+  (package
+    (name "r-experimenthub")
+    (version "1.12.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "ExperimentHub" version))
+       (sha256
+        (base32
+         "054w2lkyirbmhgia0rp4nk9zzw3zphz6jxg6fc9zlarp90g64z24"))))
+    (properties `((upstream-name . "ExperimentHub")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-annotationhub" ,r-annotationhub)
+       ("r-biocfilecache" ,r-biocfilecache)
+       ("r-biocgenerics" ,r-biocgenerics)
+       ("r-biocmanager" ,r-biocmanager)
+       ("r-curl" ,r-curl)
+       ("r-rappdirs" ,r-rappdirs)
+       ("r-s4vectors" ,r-s4vectors)))
+    (home-page "https://bioconductor.org/packages/ExperimentHub/")
+    (synopsis "Client to access ExperimentHub resources")
+    (description
+     "This package provides a client for the Bioconductor ExperimentHub web
+resource.  ExperimentHub provides a central location where curated data from
+experiments, publications or training courses can be accessed.  Each resource
+has associated metadata, tags and date of modification.  The client creates
+and manages a local cache of files retrieved enabling quick and reproducible
+access.")
+    (license license:artistic2.0)))
+
+(define-public r-multiassayexperiment
+  (package
+    (name "r-multiassayexperiment")
+    (version "1.12.4")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "MultiAssayExperiment" version))
+       (sha256
+        (base32
+         "01cnp00y5bk551c8gqgqp5468dvccg72i0rvh5cxgbx1c42zy6xn"))))
+    (properties
+     `((upstream-name . "MultiAssayExperiment")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biobase" ,r-biobase)
+       ("r-biocgenerics" ,r-biocgenerics)
+       ("r-genomicranges" ,r-genomicranges)
+       ("r-iranges" ,r-iranges)
+       ("r-s4vectors" ,r-s4vectors)
+       ("r-summarizedexperiment" ,r-summarizedexperiment)
+       ("r-tidyr" ,r-tidyr)))
+    (home-page "https://waldronlab.io/MultiAssayExperiment/")
+    (synopsis "Integration of multi-omics experiments in Bioconductor")
+    (description
+     "MultiAssayExperiment harmonizes data management of multiple assays
+performed on an overlapping set of specimens.  It provides a familiar
+Bioconductor user experience by extending concepts from
+@code{SummarizedExperiment}, supporting an open-ended mix of standard data
+classes for individual assays, and allowing subsetting by genomic ranges or
+rownames.")
+    (license license:artistic2.0)))
+
+(define-public r-bioconcotk
+  (package
+    (name "r-bioconcotk")
+    (version "1.6.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BiocOncoTK" version))
+       (sha256
+        (base32
+         "0rnah6c01a33yb9663jim9iclan61rpcwprb56mykgn1pf5hywbj"))))
+    (properties `((upstream-name . "BiocOncoTK")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-bigrquery" ,r-bigrquery)
+       ("r-car" ,r-car)
+       ("r-complexheatmap" ,r-complexheatmap)
+       ("r-curatedtcgadata" ,r-curatedtcgadata)
+       ("r-dbi" ,r-dbi)
+       ("r-dplyr" ,r-dplyr)
+       ("r-dt" ,r-dt)
+       ("r-genomicfeatures" ,r-genomicfeatures)
+       ("r-genomicranges" ,r-genomicranges)
+       ("r-ggplot2" ,r-ggplot2)
+       ("r-ggpubr" ,r-ggpubr)
+       ("r-graph" ,r-graph)
+       ("r-httr" ,r-httr)
+       ("r-iranges" ,r-iranges)
+       ("r-magrittr" ,r-magrittr)
+       ("r-plyr" ,r-plyr)
+       ("r-rgraphviz" ,r-rgraphviz)
+       ("r-rjson" ,r-rjson)
+       ("r-s4vectors" ,r-s4vectors)
+       ("r-scales" ,r-scales)
+       ("r-shiny" ,r-shiny)
+       ("r-summarizedexperiment" ,r-summarizedexperiment)))
+    (home-page "https://bioconductor.org/packages/BiocOncoTK")
+    (synopsis "Bioconductor components for general cancer genomics")
+    (description
+     "The purpose of this package is to provide a central interface to various
+tools for genome-scale analysis of cancer studies.")
+    (license license:artistic2.0)))
+
+(define-public r-biocor
+  (package
+    (name "r-biocor")
+    (version "1.10.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BioCor" version))
+       (sha256
+        (base32
+         "1bjw02rwmz2d715sgpfp08njb15200ch7cmipsf9hd5835ppg1jl"))))
+    (properties `((upstream-name . "BioCor")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biocparallel" ,r-biocparallel)
+       ("r-gseabase" ,r-gseabase)
+       ("r-matrix" ,r-matrix)))
+    (home-page "https://llrs.github.io/BioCor/")
+    (synopsis "Functional similarities")
+    (description
+     "This package provides tools to calculate functional similarities based
+on the pathways described on KEGG and REACTOME or in gene sets.  These
+similarities can be calculated for pathways or gene sets, genes, or clusters
+and combined with other similarities.  They can be used to improve networks,
+gene selection, testing relationships, and so on.")
+    (license license:expat)))
+
+(define-public r-biocpkgtools
+  (package
+    (name "r-biocpkgtools")
+    (version "1.4.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BiocPkgTools" version))
+       (sha256
+        (base32
+         "0gyhb3071pxmvaxla7cxy9k97s3z3ynl62jnqz9jnkd53c7jnd53"))))
+    (properties `((upstream-name . "BiocPkgTools")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biocmanager" ,r-biocmanager)
+       ("r-biocviews" ,r-biocviews)
+       ("r-dplyr" ,r-dplyr)
+       ("r-dt" ,r-dt)
+       ("r-gh" ,r-gh)
+       ("r-graph" ,r-graph)
+       ("r-htmltools" ,r-htmltools)
+       ("r-htmlwidgets" ,r-htmlwidgets)
+       ("r-httr" ,r-httr)
+       ("r-igraph" ,r-igraph)
+       ("r-jsonlite" ,r-jsonlite)
+       ("r-magrittr" ,r-magrittr)
+       ("r-rbgl" ,r-rbgl)
+       ("r-readr" ,r-readr)
+       ("r-rex" ,r-rex)
+       ("r-rvest" ,r-rvest)
+       ("r-stringr" ,r-stringr)
+       ("r-tibble" ,r-tibble)
+       ("r-tidyr" ,r-tidyr)
+       ("r-xml2" ,r-xml2)))
+    (home-page "https://github.com/seandavi/BiocPkgTools")
+    (synopsis "Collection of tools for learning about Bioconductor packages")
+    (description
+     "Bioconductor has a rich ecosystem of metadata around packages, usage,
+and build status.  This package is a simple collection of functions to access
+that metadata from R.  The goal is to expose metadata for data mining and
+value-added functionality such as package searching, text mining, and
+analytics on packages.")
+    (license license:expat)))
+
+(define-public r-biocset
+  (package
+    (name "r-biocset")
+    (version "1.0.1")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BiocSet" version))
+       (sha256
+        (base32
+         "1xcksnvjflrdarn8xqmgf0n6wbsjkq9jazqwp35i52vqcq4ic1j9"))))
+    (properties `((upstream-name . "BiocSet")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-annotationdbi" ,r-annotationdbi)
+       ("r-dplyr" ,r-dplyr)
+       ("r-keggrest" ,r-keggrest)
+       ("r-plyr" ,r-plyr)
+       ("r-rlang" ,r-rlang)
+       ("r-rtracklayer" ,r-rtracklayer)
+       ("r-tibble" ,r-tibble)))
+    (home-page
+     "https://bioconductor.org/packages/BiocSet")
+    (synopsis
+     "Representing Different Biological Sets")
+    (description
+     "BiocSet displays different biological sets in a triple tibble format.
+These three tibbles are @code{element}, @code{set}, and @code{elementset}.
+The user has the ability to activate one of these three tibbles to perform
+common functions from the @code{dplyr} package.  Mapping functionality and
+accessing web references for elements/sets are also available in BiocSet.")
+    (license license:artistic2.0)))
+
+(define-public r-biocworkflowtools
+  (package
+    (name "r-biocworkflowtools")
+    (version "1.12.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BiocWorkflowTools" version))
+       (sha256
+        (base32
+         "1v4bhnpdkmllm7aghms9b7369hkrgz7mn69wbrqg1x42pgkf30ad"))))
+    (properties
+     `((upstream-name . "BiocWorkflowTools")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biocstyle" ,r-biocstyle)
+       ("r-bookdown" ,r-bookdown)
+       ("r-git2r" ,r-git2r)
+       ("r-httr" ,r-httr)
+       ("r-knitr" ,r-knitr)
+       ("r-rmarkdown" ,r-rmarkdown)
+       ("r-rstudioapi" ,r-rstudioapi)
+       ("r-stringr" ,r-stringr)
+       ("r-usethis" ,r-usethis)))
+    (home-page "https://bioconductor.org/packages/BiocWorkflowTools/")
+    (synopsis "Tools to aid the development of Bioconductor Workflow packages")
+    (description
+     "This package provides functions to ease the transition between
+Rmarkdown and LaTeX documents when authoring a Bioconductor Workflow.")
+    (license license:expat)))
+
+(define-public r-biodist
+  (package
+    (name "r-biodist")
+    (version "1.58.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "bioDist" version))
+       (sha256
+        (base32
+         "0iabw07px3ybdgbbab0vv350051cm4aq8w47rz9dnmzx4kil9h5q"))))
+    (properties `((upstream-name . "bioDist")))
+    (build-system r-build-system)
+    (propagated-inputs
+     `(("r-biobase" ,r-biobase)
+       ("r-kernsmooth" ,r-kernsmooth)))
+    (home-page "https://bioconductor.org/packages/bioDist/")
+    (synopsis "Different distance measures")
+    (description
+     "This package provides a collection of software tools for calculating
+distance measures.")
+    (license license:artistic2.0)))