+(define-public r-gage
+ (package
+ (name "r-gage")
+ (version "2.28.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "gage" version))
+ (sha256
+ (base32
+ "1r14p88q3y736pkqm4pdimf1izy1xy3xgivmj3cr4dv65kjny1zk"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-graph" ,r-graph)
+ ("r-keggrest" ,r-keggrest)))
+ (home-page "http://www.biomedcentral.com/1471-2105/10/161")
+ (synopsis "Generally applicable gene-set enrichment for pathway analysis")
+ (description
+ "GAGE is a published method for gene set (enrichment or GSEA) or pathway
+analysis. GAGE is generally applicable independent of microarray or RNA-Seq
+data attributes including sample sizes, experimental designs, assay platforms,
+and other types of heterogeneity. The gage package provides functions for
+basic GAGE analysis, result processing and presentation. In addition, it
+provides demo microarray data and commonly used gene set data based on KEGG
+pathways and GO terms. These funtions and data are also useful for gene set
+analysis using other methods.")
+ (license license:gpl2+)))
+
+(define-public r-genomicfiles
+ (package
+ (name "r-genomicfiles")
+ (version "1.14.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "GenomicFiles" version))
+ (sha256
+ (base32
+ "0r0wmrs5jycf1kckhnc2sgjmp336srlcjdkpbb1ymm7kazdd0s9n"))))
+ (properties `((upstream-name . "GenomicFiles")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-biocgenerics" ,r-biocgenerics)
+ ("r-biocparallel" ,r-biocparallel)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicalignments" ,r-genomicalignments)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-iranges" ,r-iranges)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "https://bioconductor.org/packages/GenomicFiles")
+ (synopsis "Distributed computing by file or by range")
+ (description
+ "This package provides infrastructure for parallel computations
+distributed by file or by range. User defined mapper and reducer functions
+provide added flexibility for data combination and manipulation.")
+ (license license:artistic2.0)))
+
+(define-public r-complexheatmap
+ (package
+ (name "r-complexheatmap")
+ (version "1.17.1")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "ComplexHeatmap" version))
+ (sha256
+ (base32
+ "1x6kp55iqqsd8bhdl3qch95nfiy2y46ldbbsx1sj1v8f0b0ywwcy"))))
+ (properties
+ `((upstream-name . "ComplexHeatmap")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-circlize" ,r-circlize)
+ ("r-colorspace" ,r-colorspace)
+ ("r-getoptlong" ,r-getoptlong)
+ ("r-globaloptions" ,r-globaloptions)
+ ("r-rcolorbrewer" ,r-rcolorbrewer)))
+ (home-page
+ "https://github.com/jokergoo/ComplexHeatmap")
+ (synopsis "Making Complex Heatmaps")
+ (description
+ "Complex heatmaps are efficient to visualize associations between
+different sources of data sets and reveal potential structures. This package
+provides a highly flexible way to arrange multiple heatmaps and supports
+self-defined annotation graphics.")
+ (license license:gpl2+)))
+
+(define-public r-dirichletmultinomial
+ (package
+ (name "r-dirichletmultinomial")
+ (version "1.20.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "DirichletMultinomial" version))
+ (sha256
+ (base32
+ "1c4s6x0qm20556grcd1xys9kkpnlzpasaai474malwcg6qvgi4x1"))))
+ (properties
+ `((upstream-name . "DirichletMultinomial")))
+ (build-system r-build-system)
+ (inputs
+ `(("gsl" ,gsl)))
+ (propagated-inputs
+ `(("r-biocgenerics" ,r-biocgenerics)
+ ("r-iranges" ,r-iranges)
+ ("r-s4vectors" ,r-s4vectors)))
+ (home-page "https://bioconductor.org/packages/DirichletMultinomial")
+ (synopsis "Dirichlet-Multinomial mixture models for microbiome data")
+ (description
+ "Dirichlet-multinomial mixture models can be used to describe variability
+in microbial metagenomic data. This package is an interface to code
+originally made available by Holmes, Harris, and Quince, 2012, PLoS ONE 7(2):
+1-15.")
+ (license license:lgpl3)))
+
+(define-public r-ensembldb
+ (package
+ (name "r-ensembldb")
+ (version "2.2.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "ensembldb" version))
+ (sha256
+ (base32
+ "1w0lca3ws5j770bmls91cn93lznvv2pc8s42nybdzz3vdxjvb4m1"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-annotationfilter" ,r-annotationfilter)
+ ("r-annotationhub" ,r-annotationhub)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biostrings" ,r-biostrings)
+ ("r-curl" ,r-curl)
+ ("r-dbi" ,r-dbi)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-iranges" ,r-iranges)
+ ("r-protgenerics" ,r-protgenerics)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-rsqlite" ,r-rsqlite)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)))
+ (home-page "https://github.com/jotsetung/ensembldb")
+ (synopsis "Utilities to create and use Ensembl-based annotation databases")
+ (description
+ "The package provides functions to create and use transcript-centric
+annotation databases/packages. The annotation for the databases are directly
+fetched from Ensembl using their Perl API. The functionality and data is
+similar to that of the TxDb packages from the @code{GenomicFeatures} package,
+but, in addition to retrieve all gene/transcript models and annotations from
+the database, the @code{ensembldb} package also provides a filter framework
+allowing to retrieve annotations for specific entries like genes encoded on a
+chromosome region or transcript models of lincRNA genes.")
+ ;; No version specified
+ (license license:lgpl3+)))
+
+(define-public r-organismdbi
+ (package
+ (name "r-organismdbi")
+ (version "1.20.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "OrganismDbi" version))
+ (sha256
+ (base32
+ "0yxvhwn0m53wfwp0zi81x96argdf7cf1lpymc2as51apvfcnjdl8"))))
+ (properties `((upstream-name . "OrganismDbi")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biocinstaller" ,r-biocinstaller)
+ ("r-dbi" ,r-dbi)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-graph" ,r-graph)
+ ("r-iranges" ,r-iranges)
+ ("r-rbgl" ,r-rbgl)
+ ("r-s4vectors" ,r-s4vectors)))
+ (home-page "https://bioconductor.org/packages/OrganismDbi")
+ (synopsis "Software to enable the smooth interfacing of database packages")
+ (description "The package enables a simple unified interface to several
+annotation packages each of which has its own schema by taking advantage of
+the fact that each of these packages implements a select methods.")
+ (license license:artistic2.0)))
+
+(define-public r-biovizbase
+ (package
+ (name "r-biovizbase")
+ (version "1.26.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "biovizBase" version))
+ (sha256
+ (base32
+ "14l4vhj0a4ssr9m9zdzz3qpd4qw1mhgq5bmxq7jhrq3j9kmd6i2f"))))
+ (properties `((upstream-name . "biovizBase")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-annotationfilter" ,r-annotationfilter)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biostrings" ,r-biostrings)
+ ("r-dichromat" ,r-dichromat)
+ ("r-ensembldb" ,r-ensembldb)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicalignments" ,r-genomicalignments)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-hmisc" ,r-hmisc)
+ ("r-iranges" ,r-iranges)
+ ("r-rcolorbrewer" ,r-rcolorbrewer)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-scales" ,r-scales)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "https://bioconductor.org/packages/biovizBase")
+ (synopsis "Basic graphic utilities for visualization of genomic data")
+ (description
+ "The biovizBase package is designed to provide a set of utilities, color
+schemes and conventions for genomic data. It serves as the base for various
+high-level packages for biological data visualization. This saves development
+effort and encourages consistency.")
+ (license license:artistic2.0)))
+
+(define-public r-ggbio
+ (package
+ (name "r-ggbio")
+ (version "1.26.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "ggbio" version))
+ (sha256
+ (base32
+ "1bqxfqy0hff87ax92z4lfbjz01ndrz7x8pzm6dlkdmi52p30krm9"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-annotationfilter" ,r-annotationfilter)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biostrings" ,r-biostrings)
+ ("r-biovizbase" ,r-biovizbase)
+ ("r-bsgenome" ,r-bsgenome)
+ ("r-ensembldb" ,r-ensembldb)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicalignments" ,r-genomicalignments)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-ggally" ,r-ggally)
+ ("r-ggplot2" ,r-ggplot2)
+ ("r-gridextra" ,r-gridextra)
+ ("r-gtable" ,r-gtable)
+ ("r-hmisc" ,r-hmisc)
+ ("r-iranges" ,r-iranges)
+ ("r-organismdbi" ,r-organismdbi)
+ ("r-reshape2" ,r-reshape2)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-scales" ,r-scales)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "http://www.tengfei.name/ggbio/")
+ (synopsis "Visualization tools for genomic data")
+ (description
+ "The ggbio package extends and specializes the grammar of graphics for
+biological data. The graphics are designed to answer common scientific
+questions, in particular those often asked of high throughput genomics data.
+All core Bioconductor data structures are supported, where appropriate. The
+package supports detailed views of particular genomic regions, as well as
+genome-wide overviews. Supported overviews include ideograms and grand linear
+views. High-level plots include sequence fragment length, edge-linked
+interval to data view, mismatch pileup, and several splicing summaries.")
+ (license license:artistic2.0)))
+
+(define-public r-gprofiler
+ (package
+ (name "r-gprofiler")
+ (version "0.6.1")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (cran-uri "gProfileR" version))
+ (sha256
+ (base32
+ "1qix15d0wa9nspdclcawml94mng4qmr2jciv7d24py315wfsvv8p"))))
+ (properties `((upstream-name . "gProfileR")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-plyr" ,r-plyr)
+ ("r-rcurl" ,r-rcurl)))
+ (home-page "http://cran.r-project.org/web/packages/gProfileR/")
+ (synopsis "Interface to the g:Profiler toolkit")
+ (description
+ "This package provides tools for functional enrichment analysis,
+gene identifier conversion and mapping homologous genes across related
+organisms via the @code{g:Profiler} toolkit.")
+ (license license:gpl2+)))
+
+(define-public r-gqtlbase
+ (package
+ (name "r-gqtlbase")
+ (version "1.10.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "gQTLBase" version))
+ (sha256
+ (base32
+ "1756vfcj2dkkgcmfkkg7qdaig36dv9gfvpypn9rbrky56wm1p035"))))
+ (properties `((upstream-name . "gQTLBase")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-batchjobs" ,r-batchjobs)
+ ("r-bbmisc" ,r-bbmisc)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-bit" ,r-bit)
+ ("r-doparallel" ,r-doparallel)
+ ("r-ff" ,r-ff)
+ ("r-ffbase" ,r-ffbase)
+ ("r-foreach" ,r-foreach)
+ ("r-genomicfiles" ,r-genomicfiles)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)))
+ (home-page "https://bioconductor.org/packages/gQTLBase")
+ (synopsis "Infrastructure for eQTL, mQTL and similar studies")
+ (description
+ "The purpose of this package is to simplify the storage and interrogation
+of @dfn{quantitative trait loci} (QTL) archives, such as eQTL, mQTL, dsQTL,
+and more.")
+ (license license:artistic2.0)))
+
+(define-public r-snpstats
+ (package
+ (name "r-snpstats")
+ (version "1.28.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "snpStats" version))
+ (sha256
+ (base32
+ "1x9qwynh2hwl24vq02naf4mchpch7xi2pkdrlgw896k28kx0lvir"))))
+ (properties `((upstream-name . "snpStats")))
+ (build-system r-build-system)
+ (inputs `(("zlib" ,zlib)))
+ (propagated-inputs
+ `(("r-biocgenerics" ,r-biocgenerics)
+ ("r-matrix" ,r-matrix)
+ ("r-survival" ,r-survival)
+ ("r-zlibbioc" ,r-zlibbioc)))
+ (home-page "https://bioconductor.org/packages/snpStats")
+ (synopsis "Methods for SNP association studies")
+ (description
+ "This package provides classes and statistical methods for large
+@dfn{single-nucleotide polymorphism} (SNP) association studies. This extends
+the earlier snpMatrix package, allowing for uncertainty in genotypes.")
+ (license license:gpl3)))
+
+(define-public r-homo-sapiens
+ (package
+ (name "r-homo-sapiens")
+ (version "1.3.1")
+ (source (origin
+ (method url-fetch)
+ ;; We cannot use bioconductor-uri here because this tarball is
+ ;; located under "data/annotation/" instead of "bioc/".
+ (uri (string-append "http://www.bioconductor.org/packages/"
+ "release/data/annotation/src/contrib/"
+ "Homo.sapiens_"
+ version ".tar.gz"))
+ (sha256
+ (base32
+ "151vj7h5p1c8yd5swrchk46z469p135wk50hvkl0nhgndvy0jj01"))))
+ (properties
+ `((upstream-name . "Homo.sapiens")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-go-db" ,r-go-db)
+ ("r-org-hs-eg-db" ,r-org-hs-eg-db)
+ ("r-txdb-hsapiens-ucsc-hg19-knowngene" ,r-txdb-hsapiens-ucsc-hg19-knowngene)
+ ("r-organismdbi" ,r-organismdbi)
+ ("r-annotationdbi" ,r-annotationdbi)))
+ (home-page "https://bioconductor.org/packages/Homo.sapiens/")
+ (synopsis "Annotation package for the Homo.sapiens object")
+ (description
+ "This package contains the Homo.sapiens object to access data from
+several related annotation packages.")
+ (license license:artistic2.0)))
+
+(define-public r-erma
+ (package
+ (name "r-erma")
+ (version "0.10.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "erma" version))
+ (sha256
+ (base32
+ "0gcfs9g8vvdv5vmq9b21kd8sq5mizjj49nfzd4in9zvp4b9v7x1g"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-foreach" ,r-foreach)
+ ("r-genomicfiles" ,r-genomicfiles)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-ggplot2" ,r-ggplot2)
+ ("r-homo-sapiens" ,r-homo-sapiens)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-shiny" ,r-shiny)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)))
+ (home-page "https://bioconductor.org/packages/erma")
+ (synopsis "Epigenomic road map adventures")
+ (description
+ "The epigenomics road map describes locations of epigenetic marks in DNA
+from a variety of cell types. Of interest are locations of histone
+modifications, sites of DNA methylation, and regions of accessible chromatin.
+This package presents a selection of elements of the road map including
+metadata and outputs of the ChromImpute procedure applied to ENCODE cell lines
+by Ernst and Kellis.")
+ (license license:artistic2.0)))
+
+(define-public r-ldblock
+ (package
+ (name "r-ldblock")
+ (version "1.8.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "ldblock" version))
+ (sha256
+ (base32
+ "18nfsixh6d2wfrb9laqsgly5w1frzihhak683k0p8fdf51h4aqba"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-erma" ,r-erma)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicfiles" ,r-genomicfiles)
+ ("r-go-db" ,r-go-db)
+ ("r-homo-sapiens" ,r-homo-sapiens)
+ ("r-matrix" ,r-matrix)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-snpstats" ,r-snpstats)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "https://bioconductor.org/packages/ldblock")
+ (synopsis "Data structures for linkage disequilibrium measures in populations")
+ (description
+ "This package defines data structures for @dfn{linkage
+disequilibrium} (LD) measures in populations. Its purpose is to simplify
+handling of existing population-level data for the purpose of flexibly
+defining LD blocks.")
+ (license license:artistic2.0)))
+
+(define-public r-gqtlstats
+ (package
+ (name "r-gqtlstats")
+ (version "1.10.1")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "gQTLstats" version))
+ (sha256
+ (base32
+ "0gvq1sf2zjbkk431x40z6wql3c1rpclnnwa2f1hvykb8mmw70kmq"))))
+ (properties `((upstream-name . "gQTLstats")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-batchjobs" ,r-batchjobs)
+ ("r-bbmisc" ,r-bbmisc)
+ ("r-beeswarm" ,r-beeswarm)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-doparallel" ,r-doparallel)
+ ("r-dplyr" ,r-dplyr)
+ ("r-erma" ,r-erma)
+ ("r-ffbase" ,r-ffbase)
+ ("r-foreach" ,r-foreach)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicfiles" ,r-genomicfiles)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-ggbeeswarm" ,r-ggbeeswarm)
+ ("r-ggplot2" ,r-ggplot2)
+ ("r-gqtlbase" ,r-gqtlbase)
+ ("r-hardyweinberg" ,r-hardyweinberg)
+ ("r-iranges" ,r-iranges)
+ ("r-ldblock" ,r-ldblock)
+ ("r-limma" ,r-limma)
+ ("r-mgcv" ,r-mgcv)
+ ("r-plotly" ,r-plotly)
+ ("r-reshape2" ,r-reshape2)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-shiny" ,r-shiny)
+ ("r-snpstats" ,r-snpstats)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "https://bioconductor.org/packages/gQTLstats")
+ (synopsis "Computationally efficient analysis for eQTL and allied studies")
+ (description
+ "This package provides tools for the computationally efficient analysis
+of @dfn{quantitative trait loci} (QTL) data, including eQTL, mQTL, dsQTL, etc.
+The software in this package aims to support refinements and functional
+interpretation of members of a collection of association statistics on a
+family of feature/genome hypotheses.")
+ (license license:artistic2.0)))
+
+(define-public r-gviz
+ (package
+ (name "r-gviz")
+ (version "1.22.2")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "Gviz" version))
+ (sha256
+ (base32
+ "173n99mc95sij2vb8n3xd016x7mxhjs961q3l29xkg1lrnnm2sva"))))
+ (properties `((upstream-name . "Gviz")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-biobase" ,r-biobase)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biomart" ,r-biomart)
+ ("r-biostrings" ,r-biostrings)
+ ("r-biovizbase" ,r-biovizbase)
+ ("r-bsgenome" ,r-bsgenome)
+ ("r-digest" ,r-digest)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicalignments" ,r-genomicalignments)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-iranges" ,r-iranges)
+ ("r-lattice" ,r-lattice)
+ ("r-latticeextra" ,r-latticeextra)
+ ("r-matrixstats" ,r-matrixstats)
+ ("r-rcolorbrewer" ,r-rcolorbrewer)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-xvector" ,r-xvector)))
+ (home-page "https://bioconductor.org/packages/Gviz")
+ (synopsis "Plotting data and annotation information along genomic coordinates")
+ (description
+ "Genomic data analyses requires integrated visualization of known genomic
+information and new experimental data. Gviz uses the biomaRt and the
+rtracklayer packages to perform live annotation queries to Ensembl and UCSC
+and translates this to e.g. gene/transcript structures in viewports of the
+grid graphics package. This results in genomic information plotted together
+with your data.")
+ (license license:artistic2.0)))
+
+(define-public r-gwascat
+ (package
+ (name "r-gwascat")
+ (version "2.10.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "gwascat" version))
+ (sha256
+ (base32
+ "0n5x5i5v6a8wpn5mxmlpkl34b4kyypmymiwww6g61zch7xqrgywi"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-annotationdbi" ,r-annotationdbi)
+ ("r-annotationhub" ,r-annotationhub)
+ ("r-biocgenerics" ,r-biocgenerics)
+ ("r-biostrings" ,r-biostrings)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicfeatures" ,r-genomicfeatures)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-ggbio" ,r-ggbio)
+ ("r-ggplot2" ,r-ggplot2)
+ ("r-gqtlstats" ,r-gqtlstats)
+ ("r-graph" ,r-graph)
+ ("r-gviz" ,r-gviz)
+ ("r-homo-sapiens" ,r-homo-sapiens)
+ ("r-iranges" ,r-iranges)
+ ("r-rsamtools" ,r-rsamtools)
+ ("r-rtracklayer" ,r-rtracklayer)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-snpstats" ,r-snpstats)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)
+ ("r-variantannotation" ,r-variantannotation)))
+ (home-page "https://bioconductor.org/packages/gwascat")
+ (synopsis "Tools for data in the EMBL-EBI GWAS catalog")
+ (description
+ "This package provides tools for representing and modeling data in the
+EMBL-EBI GWAS catalog.")
+ (license license:artistic2.0)))
+
+(define-public r-sushi
+ (package
+ (name "r-sushi")
+ (version "1.16.0")
+ (source (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "Sushi" version))
+ (sha256
+ (base32
+ "0axaqm480z8d0b2ldgxwm0swava1p4irc62bpl17p2k8k78g687g"))))
+ (properties `((upstream-name . "Sushi")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-biomart" ,r-biomart)
+ ("r-zoo" ,r-zoo)))
+ (home-page "https://bioconductor.org/packages/Sushi")
+ (synopsis "Tools for visualizing genomics data")
+ (description
+ "This package provides flexible, quantitative, and integrative genomic
+visualizations for publication-quality multi-panel figures.")
+ (license license:gpl2+)))
+
+(define-public r-fithic
+ (package
+ (name "r-fithic")
+ (version "1.4.0")
+ (source (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "FitHiC" version))
+ (sha256
+ (base32
+ "12ylhrppi051m7nqsgq95kzd9g9wmp34i0zzfi55cjqawlpx7c6n"))))
+ (properties `((upstream-name . "FitHiC")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-data-table" ,r-data-table)
+ ("r-fdrtool" ,r-fdrtool)
+ ("r-rcpp" ,r-rcpp)))
+ (home-page "https://bioconductor.org/packages/FitHiC")
+ (synopsis "Confidence estimation for intra-chromosomal contact maps")
+ (description
+ "Fit-Hi-C is a tool for assigning statistical confidence estimates to
+intra-chromosomal contact maps produced by genome-wide genome architecture
+assays such as Hi-C.")
+ (license license:gpl2+)))
+
+(define-public r-hitc
+ (package
+ (name "r-hitc")
+ (version "1.22.0")
+ (source (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "HiTC" version))
+ (sha256
+ (base32
+ "0288xa1jy6nzvz2ha07csmp6dirjw5r7p9vy69q2wsbyzr02ymkp"))))
+ (properties `((upstream-name . "HiTC")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-biostrings" ,r-biostrings)
+ ("r-genomeinfodb" ,r-genomeinfodb)
+ ("r-genomicranges" ,r-genomicranges)
+ ("r-iranges" ,r-iranges)
+ ("r-matrix" ,r-matrix)
+ ("r-rcolorbrewer" ,r-rcolorbrewer)
+ ("r-rtracklayer" ,r-rtracklayer)))
+ (home-page "https://bioconductor.org/packages/HiTC")
+ (synopsis "High throughput chromosome conformation capture analysis")
+ (description
+ "The HiTC package was developed to explore high-throughput \"C\" data
+such as 5C or Hi-C. Dedicated R classes as well as standard methods for
+quality controls, normalization, visualization, and further analysis are also
+provided.")
+ (license license:artistic2.0)))
+
+(define-public r-qvalue
+ (package
+ (name "r-qvalue")
+ (version "2.10.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "qvalue" version))
+ (sha256
+ (base32
+ "1rd9rnf16kh8wc076kahd9hsb9rfwsbzmz3kjmp0pj6rbiq0051i"))))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-ggplot2" ,r-ggplot2)
+ ("r-reshape2" ,r-reshape2)))
+ (home-page "http://github.com/jdstorey/qvalue")
+ (synopsis "Q-value estimation for false discovery rate control")
+ (description
+ "This package takes a list of p-values resulting from the simultaneous
+testing of many hypotheses and estimates their q-values and local @dfn{false
+discovery rate} (FDR) values. The q-value of a test measures the proportion
+of false positives incurred when that particular test is called significant.
+The local FDR measures the posterior probability the null hypothesis is true
+given the test's p-value. Various plots are automatically generated, allowing
+one to make sensible significance cut-offs. The software can be applied to
+problems in genomics, brain imaging, astrophysics, and data mining.")
+ ;; Any version of the LGPL.
+ (license license:lgpl3+)))
+
+(define htslib-for-sambamba
+ (let ((commit "2f3c3ea7b301f9b45737a793c0b2dcf0240e5ee5"))
+ (package
+ (inherit htslib)
+ (name "htslib-for-sambamba")
+ (version (string-append "1.3.1-1." (string-take commit 9)))
+ (source
+ (origin
+ (method git-fetch)
+ (uri (git-reference
+ (url "https://github.com/lomereiter/htslib.git")